%This file sets the weights for isosteric subfamilies
%The symbol appearing at the start of this line is the comment symbol

%Suggested1: wI=3; wNI=2; wH=-1; wF=-2; wG1=-2; wG2=-3;
%Suggested2: wI=2; wNI=1; wF=-2;

%wI is score for Isosteric substitutions
%wNI is score for Nearly-Isosteric substitutions
%wH is score for Heterosteric substitutions
%wF is score for Forbidden substitutions
%wG1 is score for gap on one side
%wG2 is score for gap on both sides

%Write each weight on a new line
%Separate by ";"
%white spaces or extra lines do not matter
%If a value is missing, zero is used in its place 


%Next is the actual formula now applied, change it as you like:

wI=2; wNI=1; wH=-1; wF=-5; wG1=-2; wG2=-3;

