Changes in PDB files used for clustering

Release 1.13 has 231 PDB files, release 1.14 has 236 PDB files, 230 of them are identical.

1 equivalence classes changed representatives: 3V2F4NVV.

5 new structures in release 1.14: 1VW3, 1VW4, 4KR6, 4KR7, 4OOG.

Obsolete: 3V2F4V8I.

Help Every Motif Atlas release is based on a representative set of PDB files. When comparing two releases, it's important to know how the input data changed.

Representative sets are quite stable in time, but PDB files from the older releases can be replaced by newer PDB files or removed from the set altogether if the structure is obsoleted by PDB without replacement.

PDB files from the newer release either replace representatives in the existing equivalence classes or come from new equivalence classes.

Redistribution of motif instances

Loading the Sankey diagram...

Changes in motif groups

Release 1.13 has 253 motif groups, release 1.14 has 264 motif groups, 181 of them are identical.

45 motif groups were updated, 27 groups are present only in release 1.13, 38 groups are only in release 1.14.

Help The Sankey diagram shows redistribution of motif instances (loops) between two releases. The rectangles represent the motif groups and are colored as follows:

Added motif groups: green
Removed motif groups: grey
Updated motif groups: orange
Added motif instances: green
Removed motif instances: grey

Hover over the links connecting the motif groups to see which motif instances were exchanged.


Identical motif groups

#Motif idInstancesDescription
1HL_74465.513tRNA Anti-Codon loop
2HL_27271.212LSU Helix 96 (H96) Hairpin Loop
3HL_48039.211MS2 virus RNA Hairpin
4HL_15603.29U1A protein-binding Hairpin Loop.
5HL_82294.38SSU Helix 37 (h37) Hairpin loop.
6HL_42677.27
7HL_06643.36tRNA D-loop. Sec tRNA
8HL_57514.26Two base, cross-stacked hairpin loop
9HL_72543.25LSU Helix 43 (H43) Hairpin Loop. T-loop Like.
10HL_95720.15Double tSH (double sheared) with bulged base | LSU Helix 71 (H71) Hairpin Loop. | Double tSH (double sheared) with bulged base
11HL_72273.15tRNA D-loop
12HL_45018.35Hairpin-Hairpin Interacting HL
13HL_66174.15cHS GU/cWS Double Platform creates Intercalation site
14HL_55718.14UNCG-like. cWW Closing pair. | UNCG-like. cWW Closing pair. | LSU: Part of IL/3WJ between H55 and H56.
15HL_64543.24SSU Helix 31 (h31) Hairpin Loop
16HL_62881.14RNase P Structured Hairpin Loop
17HL_98523.24GNRA-like. Closed by tSH UC.
18HL_25124.24tSW GA closed tetraloops
19HL_86115.14
20HL_61547.54LSU Helix 12 (H12) Hairpin Loop. GNRA-like with altered stacking
21HL_11376.14LSU Helix 8 (H8) Hairpin Loop
22HL_98833.33
23HL_23182.13
24HL_78361.13
25HL_41827.13
26HL_80492.23tRNA D-loop
27HL_76766.43
28HL_33875.13SSU Helix 43 (h43) Hairpin Loop from T.th. T-loop like.
29HL_58083.23
30HL_19905.33LSU: Part of IL/3WJ between H55 and H56.
31HL_13707.23cSH AA Platform containing Hairpin Loop
32HL_06997.23
33HL_19221.23
34HL_93771.12tRNA T-loop distorted by RS binding
35HL_23290.12
36HL_26495.12
37HL_42553.12
38HL_90542.12
39HL_06122.12
40HL_24473.32tRNA D-loop
41HL_33451.12
42HL_87554.12
43HL_86398.12
44HL_74505.12
45HL_86123.22SSU Helix 42 (h42) Hairpin Loop. T-loop like.
46HL_17790.12UNCG-like. cWW Closing pair.
47HL_50312.12
48HL_23129.12
49HL_91872.12
50HL_60200.12
51HL_38130.22
52HL_94578.12
53HL_19528.12
54HL_74559.12Two base, cross-stacked hairpin loop
55HL_65924.12
56HL_24711.12
57HL_65249.12
58HL_19399.12
59HL_42436.12Kissing Hairpin from di-GMP-II riboswitch
60HL_62967.12
61HL_65347.12SSU Helix 43 (h43) Hairpin Loop E.coli | 16S helix 23 and 24 hairpin loops
62HL_98577.12
63HL_44467.12
64HL_18587.12
65HL_42094.12
66HL_05361.12
67HL_99633.12
68HL_96915.12
69HL_54751.22
70HL_49210.12
71HL_85044.11LSU Helix 10 (H10) Hairpin E.coli
72HL_37962.11
73HL_65071.11
74HL_44522.11
75HL_30731.11
76HL_70912.11
77HL_13786.11
78HL_55272.11
79HL_78420.11
80HL_90102.11Kink-turn-like Hairpin Loop
81HL_19452.11tRNA D-loop
82HL_08203.11
83HL_20920.11
84HL_84768.11
85HL_77692.11tRNA D-loop
86HL_65802.11
87HL_24707.11
88HL_57217.11cHS platform Intercalation Site
89HL_39422.11
90HL_79902.11
91HL_68579.11
92HL_53015.11
93HL_25175.11
94HL_95716.11
95HL_10116.11Kink-turn-like Hairpin Loop
96HL_98233.11
97HL_30008.11
98HL_38138.11
99HL_25197.11
100HL_48480.11
101HL_99779.11
102HL_52540.11
103HL_57843.11
104HL_91613.11
105HL_03785.11LSU Helix 8 (H8) Hairpin Loop
106HL_93530.11
107HL_46570.11
108HL_73465.11
109HL_42345.11
110HL_56775.11
111HL_52116.11
112HL_19226.11
113HL_95049.11Two base, cross-stacked hairpin loop
114HL_05113.11
115HL_19132.11
116HL_67000.11
117HL_62970.11
118HL_04194.11
119HL_82243.11
120HL_83865.11
121HL_79038.11LSU Helix 12 (H12) Hairpin Loop. GNRA-like with altered stacking
122HL_96994.11
123HL_55202.11U2B"-U2A" binding hairpin loop
124HL_73972.11
125HL_93567.11
126HL_57923.11
127HL_30366.11LSU Helix 10 (H10) Hairpin E.coli
128HL_45358.11Double hairpin loop based on GGA triple
129HL_84888.11T-loop like but without tWH UA
130HL_88960.11
131HL_93263.11
132HL_62880.11
133HL_78228.11
134HL_69403.11GNRA-like
135HL_23195.11
136HL_01418.11
137HL_24108.11
138HL_38898.11
139HL_59610.11
140HL_38897.11S8 operon binding Hairpin Loop. T-loop like with purine stacking.
141HL_35865.11
142HL_45411.11
143HL_20806.11
144HL_60203.11
145HL_68435.11
146HL_66877.11cSH GU/cWS double platform, intercalation site
147HL_44390.11
148HL_50059.11LSU Helix 35 (H35) Hairpin Loop from Yeast
149HL_75850.11
150HL_82288.11
151HL_49492.11Forms 7-BP PseudoKnot. Has embedded sarcin-like motif
152HL_20028.11
153HL_59182.11
154HL_17008.11Nova-2 KH3 domain binding hairpin
155HL_33640.11
156HL_78507.11
157HL_87223.11
158HL_58223.11
159HL_66880.11
160HL_56809.11
161HL_00090.11
162HL_10378.11Double 5'-stacked purine Hairpin Loop from Eukaryal LSU
163HL_99207.11Tetrahymena LSU hairpin poorly modeled
164HL_17537.11
165HL_59225.11
166HL_53789.11
167HL_25195.11
168HL_97499.11
169HL_00721.11
170HL_26579.11
171HL_84289.11
172HL_27397.11
173HL_12706.11
174HL_67761.11
175HL_63304.11
176HL_47337.11
177HL_68733.11LSU Yeast Hairpin Loop
178HL_97784.11
179HL_85018.11
180HL_99584.11
181HL_29196.11

Updated motif groups

#Motif idInstancesDescription
1HL_67042.13238GNRA Hairpin motifs
2HL_72498.1367T-loops with two bulged bases
3HL_39895.735UNCG Hairpin motifs
4HL_18781.521Double sheared (tSH) with U-turn
5HL_91226.417Kissing Hairpin motif
6HL_97270.415T-loops with 1 bulged base
7HL_52574.415LSU Helix 92 (H92) A-site Loop. GNRA-like with extra stacked base.
8HL_49036.412LSU Helix 11 (H11) Hairpin Loop. GNRA-like. | GNRA with one bulged base
9HL_56824.311LSU Helix 60A. LSU Helix 63A.
10HL_46175.31116S helix 23 and 24 hairpin loops
11HL_17723.510LSU Helix 22 (H22) Hairpin Loop. Forms Pseudknot.
12HL_68081.410LSU Helix 20 Hairpin loop
13HL_75759.510
14HL_80459.49
15HL_33402.49LSU Helix 13 (H13) Hairpin loop. GNRA-like.
16HL_24544.38LSU Helix 53 (H53) Hairpin Loop. T-loop like.
17HL_87844.38LSU Helix 11 (H11) Hairpin Loop. GNRA-like.
18HL_11547.38LSU Helix 80 (H80) P-site Hairpin Loop.
19HL_34027.385S Loop C - Upper part of Hairpin Loop.
20HL_34108.37LSU Helix 37 (H37) Hairpin Loop.
21HL_46489.37LSU H89 Hairpin Loop
22HL_18156.37LSU Helix 72 (H72) Hairpin Loop
23HL_39872.37LSU Helix 99A (H99A) Hairpin Loop. Closed by cSW AA.
24HL_70420.37LSU Helix 97 Hairpin loop
25HL_87136.37LSU Helix 39A Hairpin loop
26HL_01926.47LSU Helix 71 (H71) Hairpin Loop.
27HL_39942.37LSU Helix 91 (H91) Hairpin Loop
28HL_41833.37LSU Helix 81 (H81) Hairpin Loop
29HL_85534.26LSU Helix 65 (H65) Hairpin Loop. T-loop like.
30HL_75579.36
31HL_88311.36LSU Helix 35 (H35) Hairpin Loop
32HL_11509.36LSU Helix 6 (H6) Hairpin Loop.
33HL_62228.46LSU Helix 35A (H35A) Hairpin Loop
34HL_82538.25LSU Helix 12 (H12) Hairpin Loop. GNRA-like with altered stacking
35HL_78731.25LSU Helix 7 (H7) Hairpin Loop. Forms Pseudo-knot
36HL_48116.34GNRA-like with 5'-stacking of first unpaired base.
37HL_08382.34
38HL_35619.33
39HL_48254.23LSU Helix 84 (H84) Hairpin Loop.
40HL_68697.33
41HL_21545.23LSU Helix 96 (H96) Hairpin Loop
42HL_27429.43
43HL_64371.33SSU Central Pseudoknot (forms helix 2)
44HL_91693.23
45HL_42077.32LSU Helix 28 (H28) Hairpin Loop

Removed motif groups

#Motif idInstancesDescription
1HL_29831.14GNRA-like with bulged base.
2HL_47784.24SSU Central Pseudoknot (forms helix 2)
3HL_76036.33LSU Helix 8 (H8) Hairpin Loop
4HL_90579.33LSU Helix 69 (H69) Hairpin Loop
5HL_74686.13SSU Central Pseudoknot (forms helix 2)
6HL_32644.22LSU Helix 69 (H69) Hairpin Loop
7HL_84353.12
8HL_63941.12
9HL_16770.12
10HL_21675.32LSU Helix 12 (H12) Hairpin Loop. GNRA-like with altered stacking
11HL_66948.12LSU Helix 71 (H71) Hairpin Loop. | Double tSH (double sheared) with bulged base
12HL_42969.11
13HL_30128.11
14HL_76585.11
15HL_58601.11
16HL_76679.11
17HL_33277.11
18HL_59604.11
19HL_07915.11
20HL_34440.11
21HL_35200.11
22HL_66467.11
23HL_94697.11LSU Helix 84 (H84) Hairpin Loop. E.coli.
24HL_36842.11
25HL_97971.11
26HL_28676.11
27HL_39486.11

Added motif groups

#Motif idInstancesDescription
1HL_89236.16LSU Helix 69 (H69) Hairpin Loop
2HL_31318.15SSU Central Pseudoknot (forms helix 2)
3HL_86077.15GNRA with one bulged base | GNRA-like with bulged base.
4HL_99908.14LSU Helix 69 (H69) Hairpin Loop
5HL_82418.14LSU Helix 8 (H8) Hairpin Loop
6HL_79956.13GNRA-like with 5'-stacking of first unpaired base.
7HL_84258.13LSU Helix 28 (H28) Hairpin Loop | LSU Helix 12 (H12) Hairpin Loop. GNRA-like with altered stacking
8HL_16643.13LSU Helix 71 (H71) Hairpin Loop. | Double tSH (double sheared) with bulged base
9HL_16728.12LSU Helix 71 (H71) Hairpin Loop. | Double tSH (double sheared) with bulged base
10HL_81510.12LSU Helix 12 (H12) Hairpin Loop. GNRA-like with altered stacking
11HL_92635.12
12HL_50461.12
13HL_94309.12GNRA with one bulged base
14HL_53745.12
15HL_95756.12
16HL_38964.12LSU Helix 84 (H84) Hairpin Loop. E.coli.
17HL_46903.12
18HL_78660.12
19HL_86889.12SSU Central Pseudoknot (forms helix 2)
20HL_49998.11
21HL_19363.11
22HL_50018.11
23HL_99932.11
24HL_23080.11
25HL_93428.11
26HL_27236.11
27HL_53116.11
28HL_82622.11SSU Central Pseudoknot (forms helix 2)
29HL_04305.11
30HL_10075.11
31HL_59982.11
32HL_85982.11
33HL_96012.11
34HL_10894.11
35HL_46055.11
36HL_63997.11
37HL_97022.11
38HL_99612.11