Changes in PDB files used for clustering

Release 1.0 has 199 PDB files, release 1.1 has 199 PDB files, 197 of them are identical.

1 equivalence classes changed representatives: 2ZJR4IOA.

1 new structures in release 1.1: 3ZP8.

Obsolete: 3ZD33ZP8.

Help Every Motif Atlas release is based on a representative set of PDB files. When comparing two releases, it's important to know how the input data changed.

Representative sets are quite stable in time, but PDB files from the older releases can be replaced by newer PDB files or removed from the set altogether if the structure is obsoleted by PDB without replacement.

PDB files from the newer release either replace representatives in the existing equivalence classes or come from new equivalence classes.

Redistribution of motif instances

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Changes in motif groups

Release 1.0 has 267 motif groups, release 1.1 has 271 motif groups, 179 of them are identical.

51 motif groups were updated, 37 groups are present only in release 1.0, 41 groups are only in release 1.1.

Help The Sankey diagram shows redistribution of motif instances (loops) between two releases. The rectangles represent the motif groups and are colored as follows:

Added motif groups: green
Removed motif groups: grey
Updated motif groups: orange
Added motif instances: green
Removed motif instances: grey

Hover over the links connecting the motif groups to see which motif instances were exchanged.


Identical motif groups

#Motif idInstancesDescription
1IL_31555.315Tandem sheared with inserted, unpaired purine.
2IL_02809.29REV element IL with syn G | Tandem cWW pairs (Not AU or GC)
3IL_47444.39SRP Loop E-like motif
4IL_92114.39GAAA loop receptor "platform" motif
5IL_73000.27cHS-cWS
6IL_83451.27cHS-cWS triple and Wobble. SSU Helix 44 (h44) IL1.
7IL_70237.36
8IL_54420.16
9IL_92484.15
10IL_82188.15LSU H68 IL from H.m.
11IL_25300.1516S h19 IL and 23S H41 IL
12IL_71288.15Leadzyme Motif. LSU H101 IL2. SSU Decoding site.
13IL_77263.15Kink-turn from U4
14IL_78732.35Double S-turn motif
15IL_31066.24SSU Helix 44 (h44) extension
16IL_47758.14REV element IL with syn G | Tandem cWW pairs (Not AU or GC)
17IL_71565.24
18IL_22732.14tSH-inserted-tHS
19IL_39526.44
20IL_28572.1416S h18 kink-turn like motif
21IL_05723.13
22IL_30840.13
23IL_75447.13
24IL_79955.23SSU Helix (23) h23 IL1
25IL_82563.13Thi-box riboswitch T-loop
26IL_95150.33
27IL_80494.23LSU H58 IL2 H.m.
28IL_95652.23SSU Helix 27 (h27) IL Sarcin-Ricin motif
29IL_43946.13
30IL_52173.13
31IL_58586.23
32IL_34628.23Kink-turn
33IL_37053.13Kink-turn from 23S H58
34IL_74876.23Double-sheared with two unpaired, stacked As. LSU Helix 68 IL4.
35IL_28942.12
36IL_37197.12
37IL_46435.12
38IL_78744.12Quadruple Sheared (tSH-tSH-tHS-tHS)
39IL_09882.12
40IL_25271.12SSU Helix 8 (h8) IL E.c. and Yeast
41IL_40892.12
42IL_70280.12Double sheared with wobble cWW.
43IL_90057.12
44IL_94744.12Sarcin-ricin motif with extra cWW GA pair
45IL_98566.12
46IL_15840.22Triple Sheared with unpaired, inserted A
47IL_37406.12
48IL_57785.52SSU Decoding Site -- Human. Bulge-cSW-tHS
49IL_76095.32Motif from Hairpin Ribozyme
50IL_11751.12
51IL_16252.3223S H91 IL
52IL_21495.12
53IL_80093.12
54IL_16330.12
55IL_31707.12Vitamin B12 aptamer
56IL_50521.12
57IL_65137.12Kink-turn like motif in Group I Intron
58IL_77076.12
59IL_00998.12
60IL_12211.12
61IL_16415.12SSU Helix 23 (h23) Kink-turn T. thermophilus
62IL_23414.12
63IL_87548.12
64IL_01054.12
65IL_27892.12
66IL_45794.12
67IL_07300.12
68IL_52940.12
69IL_55287.12
70IL_89231.12LSU H77
71IL_97833.12
72IL_05462.11
73IL_09333.11SSU Helix 8 (h8) IL T. thermophilus
74IL_13682.11
75IL_20775.11tSH-inserted
76IL_25181.11
77IL_40845.11
78IL_52958.11
79IL_55649.11
80IL_60643.11
81IL_75415.11Pseudo-knot forming internal loop
82IL_82113.11
83IL_83920.11
84IL_89794.11
85IL_97842.11
86IL_02835.11
87IL_15205.11
88IL_21254.11SSU Helix 11 (h11) IL Kink-turn T. thermophilus
89IL_37347.11
90IL_53323.11
91IL_56513.11
92IL_60649.11Kink-turn
93IL_78809.11
94IL_85510.11
95IL_02957.11
96IL_06306.11
97IL_11302.11
98IL_21421.11
99IL_41139.11
100IL_47687.11
101IL_53988.11
102IL_61730.11
103IL_85805.11
104IL_91044.11
105IL_94973.11Sarcin-Ricin from Group II Intron with inserted base and poor modeling:
106IL_98655.11Part of H71 Junction in 26S rRNA from Yeast
107IL_03110.11
108IL_06468.1116S h40 3WJ E.c.
109IL_25307.11
110IL_37715.11
111IL_41791.11
112IL_57977.11
113IL_63952.11
114IL_76486.11Sarcin-ricin motif with syn G
115IL_82601.11Tandem cWW water-inserted CU pairs
116IL_86059.11
117IL_91078.11
118IL_98924.11
119IL_03282.11
120IL_06471.11
121IL_11778.11
122IL_26868.11
123IL_37990.11
124IL_43316.11
125IL_54450.11
126IL_58454.11
127IL_71685.11Sarcin-like with an intercalated basepair
128IL_82650.11
129IL_86981.11Sarcin-ricin motif with CC BIfurcated pair. H.m. LSU H18.
130IL_91089.11
131IL_03741.11
132IL_06808.11Double sheared (tSH-tSH) one bulged base.
133IL_26971.11
134IL_31754.11Sarcin-ricin H95 23S rRNA E.c.
135IL_39324.11
136IL_54576.11
137IL_65788.11
138IL_71942.11
139IL_80505.11
140IL_83250.1116S h40 3WJ T.th.
141IL_91904.11
142IL_97073.11
143IL_03931.1116S h19 IL and 23S H41 IL
144IL_06847.11Group II Intron IL
145IL_12486.11
146IL_17603.11
147IL_23639.11tWH-tHS-L-cWW
148IL_52509.11
149IL_54954.11Sarcin-Ricin with extra tSH UA basepair. Yeast LSU H11.
150IL_59529.11
151IL_66744.11SSU Helix 21 (h21) IL2 E.coli
152IL_77296.11
153IL_80652.11
154IL_88367.11
155IL_97191.11Sarcin-ricin motif with cWW UU instead of tSH basepair.
156IL_02690.11
157IL_05221.11
158IL_12507.11
159IL_17682.11Sarcin-ricin motif from Eukaryal LSU Helix 11
160IL_25082.11
161IL_40527.11Kink-turn
162IL_46306.11
163IL_59934.11SSU Helix 23 (h23) Kink-turn E. coli
164IL_67735.11
165IL_81398.11
166IL_83856.11
167IL_92280.11

Updated motif groups

#Motif idInstancesDescription
1IL_97217.62391-3 bulged nucleotides, same chain | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
2IL_47174.6201cWW AG or water inserted cWW Y-Y.
3IL_39199.354Hoogsteen-edge Platform, Single bulged base
4IL_41766.349Tandem cWW pairs (Not AU or GC)
5IL_56465.346Single, unpaired intercalated base, consensus A
6IL_44540.343Sugar-edge, 1-base platform, consensus tHS
7IL_87904.431Triple sheared (tSH-tHS-tHS) no inserted bases
8IL_06390.326cWH basepair with syn base
9IL_13959.324Double Sheared (tSH-tHS)
10IL_65553.522Kink-turn
11IL_93424.322tSH-inserted-tHW
12IL_73276.220C-loop
13IL_55938.318LSU Helix 89 (H89) IL2. cSH Platform.
14IL_92027.31716S h21 S8 binding site
15IL_24982.416SSU helix 20 (h20) IL. Prokaryal 5S Loop E Sub-motif
16IL_85647.316Sarcin-ricin parent motif with 15 Nts
17IL_94430.41516S h32-h33-h34 3WJ
18IL_49493.314Sarcin-ricin Parent Motif - bacterial LSU H95 IL
19IL_46648.21123S H91 IL | Single-Base Intercalation Site
20IL_21304.211Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
21IL_40090.31116S h34 ILa : Part of larger motif
22IL_24546.31023S H41 IL and 16S h18 IL : Has large bulge on one side
23IL_58291.39Recurrent Sub-motif found in junctions
24IL_90459.39cWW AG or UU
25IL_92321.37Triple sheared (tSH-tHS-tHS) with cWW Wobble base flanking motif
26IL_97057.36
27IL_90133.26
28IL_72158.36LSU Helix 62 (H62) IL
29IL_53635.36LSU Helix 32 (H32) IL
30IL_44067.36Quadruple sheared (tSH-tHS-tHS-tHS). LSU Helix 2 (H2).
31IL_13069.36LSU 3WJ H32-H33-H35A
32IL_25230.36Bacterial 5S rRNA Loop E
33IL_45262.35
34IL_02359.35
35IL_08926.2523S H91 IL
36IL_79083.35
37IL_86357.35LSU Helix 61 IL2
38IL_16166.3423S H91 IL
39IL_34363.24Kink-turn from 23S H42
40IL_38807.34
41IL_21333.24tSH-tHW-bulge
42IL_98591.34
43IL_93568.24Triple Sheared (tSH-tHS-tHS) with wobble cWW.
44IL_34156.63cWW AG or UU
45IL_62499.63
46IL_89028.53Part of Helix 71 (H71) junction in 23S rRNA E.c. H.m. and Tetrahymena | Part of H71 junction in 23S rRNA from T.th.
47IL_48918.23Kink-turn variant
48IL_98421.33SSU Helix 12 (h12) IL
49IL_09520.23Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW
50IL_23262.42
51IL_09348.52Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW

Removed motif groups

#Motif idInstancesDescription
1IL_91487.12116S h19 IL and 23S H41 IL | cWW-bulge-cWW
2IL_06429.315cWW-bulge-cWW
3IL_27618.21123S H73 ILa : Part of larger Motif
4IL_10007.27Single sheared with bulged bases
5IL_38960.16Double-sheared with two unpaired, stacked As. LSU Helix 68 IL4.
6IL_01239.15
7IL_98556.44
8IL_87218.1423S H91 IL
9IL_40387.44LSU Helix 89 (H89) IL2
10IL_53774.13Single sheared with bulged bases
11IL_36254.13
12IL_57216.13tHS tHH bulge with S-turn
13IL_79870.12tHS tHH bulge with S-turn
14IL_06635.12
15IL_81441.12
16IL_16377.12
17IL_87336.12LSU Eukaryal Helix 96 (H96) IL1
18IL_41397.22LSU Helix 96 (H96) IL2
19IL_64648.12tHS tHH bulge with S-turn
20IL_42397.12
21IL_25174.12
22IL_91132.12
23IL_31241.11
24IL_55934.11kink-turn-like
25IL_82519.11Part of Helix 71 (H71) junction in 23S rRNA E.c. H.m. and Tetrahymena
26IL_98688.11
27IL_11869.11
28IL_61991.11
29IL_63837.11tHS tHH bulge with S-turn
30IL_18755.11
31IL_88403.11
32IL_22579.11
33IL_75688.11Part of Helix 71 (H71) junction in 23S of D.r.
34IL_90880.11
35IL_03914.11
36IL_44803.11
37IL_77195.11

Added motif groups

#Motif idInstancesDescription
1IL_28947.12123S H91 IL | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
2IL_92109.115cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
3IL_43124.11123S H73 ILa : Part of larger Motif | Single sheared with bulged bases
4IL_39585.16Double-sheared with two unpaired, stacked As. LSU Helix 68 IL4.
5IL_16207.15Single sheared with bulged bases
6IL_01080.14
7IL_42251.14
8IL_08559.14LSU Helix 89 (H89) IL2
9IL_92267.1323S H73 ILa : Part of larger Motif
10IL_10647.13tHS tHH bulge with S-turn
11IL_56077.13
12IL_80348.1323S H91 IL
13IL_09587.12
14IL_24358.12
15IL_33964.12
16IL_49550.12tHS tHH bulge with S-turn
17IL_09901.12tHS tHH bulge with S-turn
18IL_69536.12LSU Helix 96 (H96) IL2
19IL_19898.12
20IL_88180.12cWW-bulge-cWW
21IL_33925.12
22IL_91273.12
23IL_28468.11Single sheared with bulged bases
24IL_34868.11LSU Eukaryal Helix 96 (H96) IL1
25IL_52610.11
26IL_28644.11
27IL_95774.11tHS tHH bulge with S-turn
28IL_13434.11
29IL_41341.11Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
30IL_64589.11
31IL_15674.11Part of Helix 71 (H71) junction in 23S rRNA E.c. H.m. and Tetrahymena | Part of H71 junction in 23S rRNA from T.th.
32IL_30067.11
33IL_04550.11tHS tHH bulge with S-turn
34IL_30354.11
35IL_31290.11
36IL_46721.11
37IL_09491.11
38IL_21221.11SSU Helix 12 (h12) IL
39IL_47732.11
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