Changes in PDB files used for clustering

Release 1.12 has 217 PDB files, release 1.13 has 219 PDB files, 216 of them are identical.

1 equivalence classes changed representatives: 3SD34LVZ.

2 new structures in release 1.13: 4JK0, 4NGF.

No equivalence class representatives have been obsoleted.

Help Every Motif Atlas release is based on a representative set of PDB files. When comparing two releases, it's important to know how the input data changed.

Representative sets are quite stable in time, but PDB files from the older releases can be replaced by newer PDB files or removed from the set altogether if the structure is obsoleted by PDB without replacement.

PDB files from the newer release either replace representatives in the existing equivalence classes or come from new equivalence classes.

Redistribution of motif instances

Loading the Sankey diagram...

Changes in motif groups

Release 1.12 has 276 motif groups, release 1.13 has 278 motif groups, 271 of them are identical.

2 motif groups were updated, 3 groups are present only in release 1.12, 5 groups are only in release 1.13.

Help The Sankey diagram shows redistribution of motif instances (loops) between two releases. The rectangles represent the motif groups and are colored as follows:

Added motif groups: green
Removed motif groups: grey
Updated motif groups: orange
Added motif instances: green
Removed motif instances: grey

Hover over the links connecting the motif groups to see which motif instances were exchanged.


Identical motif groups

#Motif idInstancesDescription
1IL_41766.654Tandem cWW pairs (Not AU or GC)
2IL_39199.453Hoogsteen-edge Platform, Single bulged base
3IL_56465.447Single, unpaired intercalated base, consensus A
4IL_44540.443Sugar-edge, 1-base platform, consensus tHS
5IL_87904.531Triple sheared (tSH-tHS-tHS) no inserted bases
6IL_82444.129cWH basepair with syn base | cWW AG or water inserted cWW Y-Y. | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif
7IL_13959.426Double Sheared (tSH-tHS)
8IL_65553.823Kink-turn
9IL_73276.522C-loop
10IL_28947.22223S H91 IL | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW | LSU H77 | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
11IL_93424.421tSH-inserted-tHW
12IL_55938.418LSU Helix 89 (H89) IL2. cSH Platform.
13IL_92027.31716S h21 S8 binding site
14IL_24982.516SSU helix 20 (h20) IL. Prokaryal 5S Loop E Sub-motif
15IL_94430.51616S h32-h33-h34 3WJ
16IL_85647.316Sarcin-ricin parent motif with 15 Nts
17IL_92109.315cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
18IL_31555.513Tandem sheared with inserted, unpaired purine.
19IL_49493.413Sarcin-ricin Parent Motif - bacterial LSU H95 IL
20IL_46648.61323S H91 IL | Single-Base Intercalation Site
21IL_37104.311Single sheared with bulged bases | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 23S H73 ILa : Part of larger Motif | Single sheared with bulged bases | Single sheared with bulged bases | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
22IL_17212.211cWW AG or UU | cWH basepair with syn base | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif
23IL_43124.21123S H73 ILa : Part of larger Motif | Single sheared with bulged bases
24IL_24546.41023S H41 IL and 16S h18 IL : Has large bulge on one side
25IL_58291.410Recurrent Sub-motif found in junctions
26IL_02809.39REV element IL with syn G | Tandem cWW pairs (Not AU or GC)
27IL_90459.39cWW AG or UU
28IL_92114.39GAAA loop receptor "platform" motif
29IL_47444.39SRP Loop E-like motif
30IL_46301.17Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW | Leadzyme Motif. LSU H101 IL2. SSU Decoding site. | Tandem sheared with inserted, unpaired purine. | cHS-cWS triple and Wobble. SSU Helix 44 (h44) IL1.
31IL_25300.3716S h19 IL and 23S H41 IL
32IL_92321.47Triple sheared (tSH-tHS-tHS) with cWW Wobble base flanking motif
33IL_73000.27cHS-cWS
34IL_97057.36
35IL_70173.16Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif | cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
36IL_77263.26Kink-turn from U4
37IL_53635.36LSU Helix 32 (H32) IL
38IL_08926.3623S H91 IL
39IL_13069.36LSU 3WJ H32-H33-H35A
40IL_90133.36
41IL_72158.36LSU Helix 62 (H62) IL
42IL_70237.36
43IL_39585.16Double-sheared with two unpaired, stacked As. LSU Helix 68 IL4.
44IL_25230.36Bacterial 5S rRNA Loop E
45IL_25380.16LSU Helix 89 (H89) IL2
46IL_44067.45Quadruple sheared (tSH-tHS-tHS-tHS). LSU Helix 2 (H2).
47IL_86357.35LSU Helix 61 IL2
48IL_05684.15tHS tHH bulge with S-turn | Double S-turn motif
49IL_79083.35
50IL_02359.35
51IL_34363.24Kink-turn from 23S H42
52IL_45262.44
53IL_97296.14Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW | Leadzyme Motif. LSU H101 IL2. SSU Decoding site.
54IL_28572.2416S h18 kink-turn like motif
55IL_95652.34SSU Helix 27 (h27) IL Sarcin-Ricin motif
56IL_21333.24tSH-tHW-bulge
57IL_31066.34SSU Helix 44 (h44) extension
58IL_39980.14
59IL_47758.24REV element IL with syn G | Tandem cWW pairs (Not AU or GC)
60IL_54966.14cHS-cWS triple and Wobble. SSU Helix 44 (h44) IL1.
61IL_98591.34
62IL_01080.14
63IL_82188.24LSU H68 IL from H.m.
64IL_93568.24Triple Sheared (tSH-tHS-tHS) with wobble cWW.
65IL_09530.14Double S-turn motif
66IL_48918.34Kink-turn variant
67IL_22732.14tSH-inserted-tHS
68IL_94403.54LSU H77
69IL_42251.14
70IL_38807.34
71IL_31663.1423S H73 ILa : Part of larger Motif
72IL_39526.44
73IL_16415.23SSU Helix 23 (h23) Kink-turn T. thermophilus
74IL_95150.63
75IL_62499.73
76IL_28003.13
77IL_06180.13tHS tHH bulge with S-turn
78IL_30840.23
79IL_80348.3323S H91 IL
80IL_47875.13LSU H77 | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
81IL_35043.13cWW AG or UU | cWH basepair with syn base | cWH basepair with syn base
82IL_16166.4323S H91 IL
83IL_43946.13
84IL_98421.43SSU Helix 12 (h12) IL
85IL_05723.13
86IL_89028.63Part of Helix 71 (H71) junction in 23S rRNA E.c. H.m. and Tetrahymena | Part of H71 junction in 23S rRNA from T.th.
87IL_07300.23
88IL_06211.33
89IL_52173.13
90IL_58586.23
91IL_82563.13Thi-box riboswitch T-loop
92IL_87065.1323S H91 IL | Single-Base Intercalation Site
93IL_34628.23Kink-turn
94IL_80494.23LSU H58 IL2 H.m.
95IL_25271.23SSU Helix 8 (h8) IL E.c. and Yeast
96IL_74876.23Double-sheared with two unpaired, stacked As. LSU Helix 68 IL4.
97IL_79955.23SSU Helix (23) h23 IL1
98IL_37053.13Kink-turn from 23S H58
99IL_52940.12
100IL_09882.12
101IL_77076.12
102IL_21495.12
103IL_37406.12
104IL_46990.12
105IL_43877.12Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif | cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
106IL_90735.12
107IL_40892.12
108IL_33964.12
109IL_78744.12Quadruple Sheared (tSH-tSH-tHS-tHS)
110IL_11751.12
111IL_90057.12
112IL_98566.12
113IL_12211.12
114IL_15840.22Triple Sheared with unpaired, inserted A
115IL_65137.12Kink-turn like motif in Group I Intron
116IL_69106.12Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW
117IL_23262.42
118IL_69536.12LSU Helix 96 (H96) IL2
119IL_94744.12Sarcin-ricin motif with extra cWW GA pair
120IL_23414.12
121IL_39355.12SSU Helix 12 (h12) IL | LSU Eukaryal Helix 96 (H96) IL1
122IL_31707.12Vitamin B12 aptamer
123IL_97833.12
124IL_57785.52SSU Decoding Site -- Human. Bulge-cSW-tHS
125IL_24293.1223S H73 ILa : Part of larger Motif | Single sheared with bulged bases | 23S H73 ILa : Part of larger Motif | Single sheared with bulged bases | Single sheared with bulged bases | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
126IL_46034.32
127IL_76095.32Motif from Hairpin Ribozyme
128IL_30381.12tHS tHH bulge with S-turn
129IL_31039.12
130IL_67887.12
131IL_21639.12
132IL_70401.12
133IL_80093.12
134IL_00998.12
135IL_37197.12
136IL_33842.12
137IL_50521.12
138IL_09587.12
139IL_97509.12Double sheared with wobble cWW.
140IL_45794.12
141IL_87548.12
142IL_96206.32
143IL_46435.12
144IL_16330.12
145IL_87507.12tHS tHH bulge with S-turn
146IL_63952.11
147IL_86059.11
148IL_43316.11
149IL_12507.11
150IL_69799.11
151IL_47687.11
152IL_80652.11
153IL_54450.11
154IL_37347.11
155IL_46306.11
156IL_82601.11Tandem cWW water-inserted CU pairs
157IL_91089.11
158IL_60649.11Kink-turn
159IL_47732.11
160IL_09333.11SSU Helix 8 (h8) IL T. thermophilus
161IL_80505.11
162IL_22909.11
163IL_55649.11
164IL_31754.11Sarcin-ricin H95 23S rRNA E.c.
165IL_31224.1123S H91 IL
166IL_05221.11
167IL_06471.11
168IL_68767.11
169IL_17603.11
170IL_17682.11Sarcin-ricin motif from Eukaryal LSU Helix 11
171IL_99397.11cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
172IL_77296.11
173IL_13777.11cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
174IL_21254.11SSU Helix 11 (h11) IL Kink-turn T. thermophilus
175IL_06177.11cWW AG or UU
176IL_82650.11
177IL_26868.11
178IL_25082.11
179IL_53323.11
180IL_26971.11
181IL_56513.11
182IL_15205.11
183IL_87523.11
184IL_03282.11
185IL_46721.11
186IL_40845.11
187IL_25307.11
188IL_11302.11
189IL_89794.11
190IL_28644.11
191IL_52509.11
192IL_75415.11Pseudo-knot forming internal loop
193IL_88119.11
194IL_98924.11
195IL_59529.11
196IL_91904.11
197IL_21421.11
198IL_85510.11
199IL_21077.11
200IL_94973.11Sarcin-Ricin from Group II Intron with inserted base and poor modeling:
201IL_41153.11
202IL_03110.11
203IL_02835.11
204IL_76263.11
205IL_66744.11SSU Helix 21 (h21) IL2 E.coli
206IL_53988.11
207IL_61730.11
208IL_71685.11Sarcin-like with an intercalated basepair
209IL_25181.11
210IL_09491.11
211IL_58454.11
212IL_88367.11
213IL_49527.11
214IL_30067.11
215IL_50911.1116S h34 ILa : Part of larger motif
216IL_80714.11
217IL_86981.11Sarcin-ricin motif with CC BIfurcated pair. H.m. LSU H18.
218IL_41791.11
219IL_68827.11Reverse Kink-Turn
220IL_83920.11
221IL_59934.11SSU Helix 23 (h23) Kink-turn E. coli
222IL_11778.11
223IL_91078.11
224IL_06306.11
225IL_54954.11Sarcin-Ricin with extra tSH UA basepair. Yeast LSU H11.
226IL_23639.11tWH-tHS-L-cWW
227IL_02957.11
228IL_18675.11cWW-bulge-cWW
229IL_40527.11Kink-turn
230IL_49976.11
231IL_52610.11
232IL_85805.11
233IL_57977.11
234IL_39324.11
235IL_02897.11Part of Helix 71 (H71) junction in 23S rRNA E.c. H.m. and Tetrahymena | Part of H71 junction in 23S rRNA from T.th.
236IL_97191.11Sarcin-ricin motif with cWW UU instead of tSH basepair.
237IL_06421.11Single sheared with bulged bases
238IL_20775.11tSH-inserted
239IL_83856.11
240IL_76486.11Sarcin-ricin motif with syn G
241IL_70299.11
242IL_57364.11LSU Helix 89 (H89) IL2
243IL_41139.11
244IL_91044.11
245IL_87394.11
246IL_05513.11
247IL_83250.1116S h40 3WJ T.th.
248IL_63253.11LSU H77 | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
249IL_06468.1116S h40 3WJ E.c.
250IL_52958.11
251IL_06808.11Double sheared (tSH-tSH) one bulged base.
252IL_71942.11
253IL_86336.11
254IL_81398.11
255IL_97842.11
256IL_98655.11Part of H71 Junction in 26S rRNA from Yeast
257IL_64589.11
258IL_54470.11tHS tHH bulge with S-turn
259IL_06847.11Group II Intron IL
260IL_42891.11
261IL_78513.11

Updated motif groups

#Motif idInstancesDescription
1IL_97217.112481-3 bulged nucleotides, same chain | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
2IL_47174.11219cWW AG or water inserted cWW Y-Y.

Removed motif groups

#Motif idInstancesDescription
1IL_21644.12Single sheared with bulged bases | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
2IL_12024.12
3IL_03741.11

Added motif groups

#Motif idInstancesDescription
1IL_12147.12Single sheared with bulged bases | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
2IL_27640.11
3IL_37325.11
4IL_63133.11Single sheared with bulged bases | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
5IL_17066.11