Changes in PDB files used for clustering

Release 1.13 has 219 PDB files, release 1.14 has 222 PDB files, 218 of them are identical.

1 equivalence classes changed representatives: 3V2F4NVV.

3 new structures in release 1.14: 1VW3, 4KR6, 4KR7.

Obsolete: 3V2F4V8I.

Help Every Motif Atlas release is based on a representative set of PDB files. When comparing two releases, it's important to know how the input data changed.

Representative sets are quite stable in time, but PDB files from the older releases can be replaced by newer PDB files or removed from the set altogether if the structure is obsoleted by PDB without replacement.

PDB files from the newer release either replace representatives in the existing equivalence classes or come from new equivalence classes.

Redistribution of motif instances

Loading the Sankey diagram...

Changes in motif groups

Release 1.13 has 278 motif groups, release 1.14 has 282 motif groups, 172 of them are identical.

53 motif groups were updated, 53 groups are present only in release 1.13, 57 groups are only in release 1.14.

Help The Sankey diagram shows redistribution of motif instances (loops) between two releases. The rectangles represent the motif groups and are colored as follows:

Added motif groups: green
Removed motif groups: grey
Updated motif groups: orange
Added motif instances: green
Removed motif instances: grey

Hover over the links connecting the motif groups to see which motif instances were exchanged.


Identical motif groups

#Motif idInstancesDescription
1IL_47444.39SRP Loop E-like motif
2IL_02809.39REV element IL with syn G | Tandem cWW pairs (Not AU or GC)
3IL_92114.39GAAA loop receptor "platform" motif
4IL_73000.27cHS-cWS
5IL_92321.47Triple sheared (tSH-tHS-tHS) with cWW Wobble base flanking motif
6IL_77263.26Kink-turn from U4
7IL_22732.14tSH-inserted-tHS
8IL_82188.24LSU H68 IL from H.m.
9IL_31663.1423S H73 ILa : Part of larger Motif
10IL_28572.2416S h18 kink-turn like motif
11IL_42251.14
12IL_47758.24REV element IL with syn G | Tandem cWW pairs (Not AU or GC)
13IL_95652.34SSU Helix 27 (h27) IL Sarcin-Ricin motif
14IL_01080.14
15IL_39526.44
16IL_48918.34Kink-turn variant
17IL_39980.14
18IL_34363.24Kink-turn from 23S H42
19IL_31066.34SSU Helix 44 (h44) extension
20IL_74876.23Double-sheared with two unpaired, stacked As. LSU Helix 68 IL4.
21IL_79955.23SSU Helix (23) h23 IL1
22IL_82563.13Thi-box riboswitch T-loop
23IL_80348.3323S H91 IL
24IL_43946.13
25IL_06180.13tHS tHH bulge with S-turn
26IL_07300.23
27IL_25271.23SSU Helix 8 (h8) IL E.c. and Yeast
28IL_06211.33
29IL_30840.23
30IL_34628.23Kink-turn
31IL_52173.13
32IL_37053.13Kink-turn from 23S H58
33IL_09587.12
34IL_37197.12
35IL_78744.12Quadruple Sheared (tSH-tSH-tHS-tHS)
36IL_90057.12
37IL_94744.12Sarcin-ricin motif with extra cWW GA pair
38IL_09882.12
39IL_16330.12
40IL_52940.12
41IL_90735.12
42IL_23414.12
43IL_31707.12Vitamin B12 aptamer
44IL_65137.12Kink-turn like motif in Group I Intron
45IL_76095.32Motif from Hairpin Ribozyme
46IL_80093.12
47IL_11751.12
48IL_33842.12
49IL_77076.12
50IL_87548.12
51IL_97833.12
52IL_12147.12Single sheared with bulged bases | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
53IL_30381.12tHS tHH bulge with S-turn
54IL_45794.12
55IL_50521.12
56IL_70401.12
57IL_12211.12
58IL_21495.12
59IL_98566.12
60IL_21639.12
61IL_40892.12
62IL_46435.12
63IL_03110.11
64IL_06421.11Single sheared with bulged bases
65IL_15205.11
66IL_26971.11
67IL_31224.1123S H91 IL
68IL_41139.11
69IL_52610.11
70IL_55649.11
71IL_63952.11
72IL_86059.11
73IL_98924.11
74IL_03282.11
75IL_06468.1116S h40 3WJ E.c.
76IL_22909.11
77IL_27640.11
78IL_37347.11
79IL_41791.11
80IL_47687.11
81IL_57977.11
82IL_64589.11
83IL_75415.11Pseudo-knot forming internal loop
84IL_86336.11
85IL_94973.11Sarcin-Ricin from Group II Intron with inserted base and poor modeling:
86IL_05221.11
87IL_06471.11
88IL_11302.11
89IL_17682.11Sarcin-ricin motif from Eukaryal LSU Helix 11
90IL_39324.11
91IL_52958.11
92IL_59529.11
93IL_82601.11Tandem cWW water-inserted CU pairs
94IL_86981.11Sarcin-ricin motif with CC BIfurcated pair. H.m. LSU H18.
95IL_91044.11
96IL_05513.11
97IL_06808.11Double sheared (tSH-tSH) one bulged base.
98IL_20775.11tSH-inserted
99IL_23639.11tWH-tHS-L-cWW
100IL_28644.11
101IL_31754.11Sarcin-ricin H95 23S rRNA E.c.
102IL_43316.11
103IL_53323.11
104IL_59934.11SSU Helix 23 (h23) Kink-turn E. coli
105IL_66744.11SSU Helix 21 (h21) IL2 E.coli
106IL_76486.11Sarcin-ricin motif with syn G
107IL_82650.11
108IL_87523.11
109IL_91078.11
110IL_97191.11Sarcin-ricin motif with cWW UU instead of tSH basepair.
111IL_06177.11cWW AG or UU
112IL_06847.11Group II Intron IL
113IL_11778.11
114IL_21077.11
115IL_25082.11
116IL_30067.11
117IL_49527.11
118IL_53988.11
119IL_60649.11Kink-turn
120IL_68767.11
121IL_80505.11
122IL_83250.1116S h40 3WJ T.th.
123IL_91089.11
124IL_02835.11
125IL_21254.11SSU Helix 11 (h11) IL Kink-turn T. thermophilus
126IL_40527.11Kink-turn
127IL_54450.11
128IL_61730.11
129IL_80652.11
130IL_83920.11
131IL_88119.11
132IL_91904.11
133IL_97842.11
134IL_02897.11Part of Helix 71 (H71) junction in 23S rRNA E.c. H.m. and Tetrahymena | Part of H71 junction in 23S rRNA from T.th.
135IL_09333.11SSU Helix 8 (h8) IL T. thermophilus
136IL_25307.11
137IL_40845.11
138IL_46306.11
139IL_54470.11tHS tHH bulge with S-turn
140IL_63133.11Single sheared with bulged bases | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
141IL_71685.11Sarcin-like with an intercalated basepair
142IL_77296.11
143IL_80714.11
144IL_85510.11
145IL_88367.11
146IL_02957.11
147IL_06306.11
148IL_09491.11
149IL_12507.11
150IL_26868.11
151IL_52509.11
152IL_54954.11Sarcin-Ricin with extra tSH UA basepair. Yeast LSU H11.
153IL_63253.11LSU H77 | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
154IL_78513.11
155IL_81398.11
156IL_85805.11
157IL_89794.11
158IL_98655.11Part of H71 Junction in 26S rRNA from Yeast

Updated motif groups

#Motif idInstancesDescription
1IL_97217.122621-3 bulged nucleotides, same chain | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
2IL_41766.757Tandem cWW pairs (Not AU or GC)
3IL_39199.556Hoogsteen-edge Platform, Single bulged base
4IL_56465.551Single, unpaired intercalated base, consensus A
5IL_44540.545Sugar-edge, 1-base platform, consensus tHS
6IL_87904.632Triple sheared (tSH-tHS-tHS) no inserted bases
7IL_82444.228cWW AG or UU | cWH basepair with syn base | cWH basepair with syn base | cWH basepair with syn base | cWW AG or water inserted cWW Y-Y. | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif
8IL_13959.527Double Sheared (tSH-tHS)
9IL_73276.624C-loop
10IL_28947.32423S H91 IL | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW | LSU H77 | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
11IL_65553.923Kink-turn
12IL_93424.522tSH-inserted-tHW
13IL_92027.41916S h21 S8 binding site
14IL_85647.418Sarcin-ricin parent motif with 15 Nts
15IL_55938.517LSU Helix 89 (H89) IL2. cSH Platform.
16IL_24982.616SSU helix 20 (h20) IL. Prokaryal 5S Loop E Sub-motif
17IL_49493.515Sarcin-ricin Parent Motif - bacterial LSU H95 IL
18IL_46648.71423S H91 IL | Single-Base Intercalation Site
19IL_94430.61416S h32-h33-h34 3WJ
20IL_31555.613Tandem sheared with inserted, unpaired purine. | Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW | Leadzyme Motif. LSU H101 IL2. SSU Decoding site. | Tandem sheared with inserted, unpaired purine. | cHS-cWS triple and Wobble. SSU Helix 44 (h44) IL1.
21IL_37104.413Single sheared with bulged bases | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 23S H73 ILa : Part of larger Motif | Single sheared with bulged bases | Single sheared with bulged bases | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
22IL_43124.31323S H73 ILa : Part of larger Motif | Single sheared with bulged bases
23IL_24546.51023S H41 IL and 16S h18 IL : Has large bulge on one side
24IL_58291.510Recurrent Sub-motif found in junctions
25IL_08926.4723S H91 IL
26IL_53635.47LSU Helix 32 (H32) IL
27IL_97057.47
28IL_25230.46Bacterial 5S rRNA Loop E
29IL_13069.46LSU 3WJ H32-H33-H35A
30IL_93568.36Triple Sheared (tSH-tHS-tHS) with wobble cWW.
31IL_86357.46LSU Helix 61 IL2
32IL_70237.46
33IL_72158.46LSU Helix 62 (H62) IL
34IL_44067.55Quadruple sheared (tSH-tHS-tHS-tHS). LSU Helix 2 (H2).
35IL_90133.45
36IL_09530.25Double S-turn motif
37IL_79083.45
38IL_02359.45
39IL_16166.5423S H91 IL
40IL_87065.2423S H91 IL | Single-Base Intercalation Site
41IL_58586.33
42IL_62499.83
43IL_97509.23Double sheared with wobble cWW.
44IL_98421.53SSU Helix 12 (h12) IL | SSU Helix 12 (h12) IL | LSU Eukaryal Helix 96 (H96) IL1
45IL_67887.23
46IL_69106.23Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW | Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW | Leadzyme Motif. LSU H101 IL2. SSU Decoding site.
47IL_94403.63LSU H77
48IL_69536.23LSU Helix 96 (H96) IL2
49IL_05723.23
50IL_28003.22
51IL_80494.32LSU H58 IL2 H.m.
52IL_16415.32SSU Helix 23 (h23) Kink-turn T. thermophilus
53IL_95150.72

Removed motif groups

#Motif idInstancesDescription
1IL_47174.11219cWW AG or water inserted cWW Y-Y.
2IL_92109.315cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
3IL_17212.211cWW AG or UU | cWH basepair with syn base | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif
4IL_90459.39cWW AG or UU
5IL_46301.17Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW | Leadzyme Motif. LSU H101 IL2. SSU Decoding site. | Tandem sheared with inserted, unpaired purine. | cHS-cWS triple and Wobble. SSU Helix 44 (h44) IL1.
6IL_25300.3716S h19 IL and 23S H41 IL
7IL_25380.16LSU Helix 89 (H89) IL2
8IL_39585.16Double-sheared with two unpaired, stacked As. LSU Helix 68 IL4.
9IL_70173.16Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif | cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
10IL_05684.15tHS tHH bulge with S-turn | Double S-turn motif
11IL_97296.14Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW | Leadzyme Motif. LSU H101 IL2. SSU Decoding site.
12IL_54966.14cHS-cWS triple and Wobble. SSU Helix 44 (h44) IL1.
13IL_98591.34
14IL_38807.34
15IL_21333.24tSH-tHW-bulge
16IL_45262.44
17IL_89028.63Part of Helix 71 (H71) junction in 23S rRNA E.c. H.m. and Tetrahymena | Part of H71 junction in 23S rRNA from T.th.
18IL_47875.13LSU H77 | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
19IL_35043.13cWW AG or UU | cWH basepair with syn base | cWH basepair with syn base
20IL_23262.42
21IL_46034.32
22IL_15840.22Triple Sheared with unpaired, inserted A
23IL_24293.1223S H73 ILa : Part of larger Motif | Single sheared with bulged bases | 23S H73 ILa : Part of larger Motif | Single sheared with bulged bases | Single sheared with bulged bases | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
24IL_37406.12
25IL_39355.12SSU Helix 12 (h12) IL | LSU Eukaryal Helix 96 (H96) IL1
26IL_46990.12
27IL_87507.12tHS tHH bulge with S-turn
28IL_57785.52SSU Decoding Site -- Human. Bulge-cSW-tHS
29IL_31039.12
30IL_00998.12
31IL_33964.12
32IL_43877.12Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif | cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
33IL_96206.32
34IL_13777.11cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
35IL_37325.11
36IL_50911.1116S h34 ILa : Part of larger motif
37IL_70299.11
38IL_71942.11
39IL_17066.11
40IL_25181.11
41IL_46721.11
42IL_56513.11
43IL_83856.11
44IL_99397.11cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
45IL_57364.11LSU Helix 89 (H89) IL2
46IL_17603.11
47IL_18675.11cWW-bulge-cWW
48IL_41153.11
49IL_47732.11
50IL_58454.11
51IL_69799.11
52IL_21421.11
53IL_49976.11

Added motif groups

#Motif idInstancesDescription
1IL_78141.1228cWW AG or UU | cWW AG or water inserted cWW Y-Y. | cWH basepair with syn base | cWW AG or water inserted cWW Y-Y. | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif
2IL_37056.1161-3 bulged nucleotides, same chain | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
3IL_67813.115cWW AG or water inserted cWW Y-Y. | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif | cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | cWW AG or UU | cWH basepair with syn base | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif | 16S h34 ILa : Part of larger motif
4IL_65554.18cHS-cWS triple and Wobble. SSU Helix 44 (h44) IL1. | Tandem sheared with inserted, unpaired purine. | Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW | Leadzyme Motif. LSU H101 IL2. SSU Decoding site. | Tandem sheared with inserted, unpaired purine. | cHS-cWS triple and Wobble. SSU Helix 44 (h44) IL1.
5IL_55214.18Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW | Leadzyme Motif. LSU H101 IL2. SSU Decoding site.
6IL_74856.18LSU Helix 89 (H89) IL2
7IL_71837.18cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif | cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | cWH basepair with syn base | cWW AG or water inserted cWW Y-Y. | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif | cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
8IL_64847.17Double-sheared with two unpaired, stacked As. LSU Helix 68 IL4.
9IL_04397.15
10IL_48183.15tSH-tHW-bulge
11IL_59864.15
12IL_82133.15SSU Decoding Site -- Human. Bulge-cSW-tHS | Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW | Leadzyme Motif. LSU H101 IL2. SSU Decoding site. | Tandem sheared with inserted, unpaired purine. | cHS-cWS triple and Wobble. SSU Helix 44 (h44) IL1.
13IL_16029.15cWW AG or water inserted cWW Y-Y. | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif | cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
14IL_71229.15
15IL_46960.1516S h19 IL and 23S H41 IL | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
16IL_55114.14tHS tHH bulge with S-turn | Double S-turn motif
17IL_08763.14LSU H77 | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL
18IL_66654.14Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif | cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif | cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | cWW AG or UU | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
19IL_56594.14cWW AG or UU
20IL_15123.14Part of Helix 71 (H71) junction in 23S rRNA E.c. H.m. and Tetrahymena | Part of H71 junction in 23S rRNA from T.th.
21IL_32261.14LSU Helix 89 (H89) IL2
22IL_37171.13LSU H58 IL2 H.m.
23IL_72641.13cWW AG or UU | cWH basepair with syn base | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75) | 16S h34 ILa : Part of larger motif
24IL_95908.13LSU H77 | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW | cWW-bulge-cWW | 16S h19 IL and 23S H41 IL | cWW-bulge-cWW
25IL_89252.13
26IL_90877.12
27IL_05641.12
28IL_25541.12Triple Sheared with unpaired, inserted A
29IL_39175.12
30IL_92422.12
31IL_92576.12
32IL_12204.12
33IL_67024.12
34IL_30534.12
35IL_43545.12Leadzyme Motif. SSU Decoding site motif, extended. | cWW-L-cWW-cWW | Leadzyme Motif. LSU H101 IL2. SSU Decoding site. | Tandem sheared with inserted, unpaired purine. | cHS-cWS triple and Wobble. SSU Helix 44 (h44) IL1.
36IL_60613.12
37IL_16977.12
38IL_87064.12tHS tHH bulge with S-turn
39IL_25420.11
40IL_73656.11
41IL_25771.11
42IL_41027.11
43IL_26448.11
44IL_41516.11
45IL_96920.11SSU Helix 12 (h12) IL
46IL_45432.11
47IL_86453.1123S H73 ILa : Part of larger Motif | Single sheared with bulged bases | 23S H73 ILa : Part of larger Motif | Single sheared with bulged bases | Single sheared with bulged bases | Single sheared (tHS) with bulged bases. LSU Helix 75 (H75)
48IL_99937.11
49IL_03625.11
50IL_36006.11
51IL_46151.11Triple Sheared with unpaired, inserted A
52IL_62296.11
53IL_03808.11
54IL_23302.11
55IL_64213.11SSU Helix 12 (h12) IL | LSU Eukaryal Helix 96 (H96) IL1
56IL_72293.11