#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. ÅDate
18GLP|1|L5+ 8GLP|1|L8 (rep)Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)Electron microscopy1.672023-04-19
28A3D|1|A+ 8A3D|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human mature large subunit of the ribosome with eIF6 and homoharringtonine boundElectron microscopy1.672023-03-08
38G5Y|1|L5+ 8G5Y|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)Electron microscopy2.292023-04-19
47XNY|1|L1+ 7XNY|1|L3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsElectron microscopy2.52023-04-05
56ZMI|1|L5+ 6ZMI|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complexElectron microscopy2.62020-08-19
67OW7|1|A+ 7OW7|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002EIF6-bound large subunit of the human ribosomeElectron microscopy2.22022-10-05
76ZM7|1|L5+ 6ZM7|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complexElectron microscopy2.72020-07-29
88G60|1|L5+ 8G60|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)Electron microscopy2.542023-04-19
97XNX|1|L1+ 7XNX|1|L3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cellsElectron microscopy2.72023-04-05
108G5Z|1|L5+ 8G5Z|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)Electron microscopy2.642023-04-19
117F5S|1|L5+ 7F5S|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human delta-METTL18 60S ribosomeElectron microscopy2.722022-06-22
128FL3|1|L3+ 8FL3|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State I2)Electron microscopy2.532023-07-12
136Y6X|1|L5+ 6Y6X|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Tetracenomycin X bound to the human ribosomeElectron microscopy2.82020-07-08
146Z6N|1|L5+ 6Z6N|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)Electron microscopy2.92020-07-29
158FLE|1|L3+ 8FLE|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State L2)Electron microscopy2.482023-07-12
168FLB|1|L3+ 8FLB|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State K2)Electron microscopy2.552023-07-12
178FL7|1|L3+ 8FL7|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State J2)Electron microscopy2.552023-07-12
188G6J|1|L5+ 8G6J|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)Electron microscopy2.82023-04-19
196QZP|1|L5+ 6QZP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA (3773-MER), 5.8S rRNA (156-MER)Homo sapiensEukaryaRF02543 + RF00002High-resolution cryo-EM structure of the human 80S ribosomeElectron microscopy2.92019-04-24
206ZME|1|L5+ 6ZME|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complexElectron microscopy32020-08-12
216Z6L|1|L5+ 6Z6L|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human CCDC124 bound to 80S ribosomesElectron microscopy32020-07-29
227QVP|1|L5+ 7QVP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human collided disome (di-ribosome) stalled on XBP1 mRNAElectron microscopy32022-10-12
238FLD|1|L3+ 8FLD|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State L1)Electron microscopy2.582023-07-12
248FL6|1|L3+ 8FL6|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State J1)Electron microscopy2.622023-07-12
258FLA|1|L3+ 8FLA|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State K1)Electron microscopy2.632023-07-12
268FL2|1|L3+ 8FL2|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State I1)Electron microscopy2.672023-07-12
277QVP|1|L6+ 7QVP|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human collided disome (di-ribosome) stalled on XBP1 mRNAElectron microscopy32022-10-12
286XA1|1|L5+ 6XA1|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Structure of a drug-like compound stalled human translation termination complexElectron microscopy2.82020-10-07
296ZMO|1|L5+ 6ZMO|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complexElectron microscopy3.12020-08-19
306Z6M|1|L5+ 6Z6M|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1Electron microscopy3.12020-07-29
318FLF|1|L3+ 8FLF|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State L3)Electron microscopy2.652023-07-12
328G61|1|L5+ 8G61|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)Electron microscopy2.942023-04-19
338FL9|1|L3+ 8FL9|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State J3)Electron microscopy2.752023-07-12
348FLC|1|L3+ 8FLC|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State K3)Electron microscopy2.762023-07-12
356OLE|1|t+ 6OLE|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAsElectron microscopy3.12019-06-19
366OM0|1|t+ 6OM0|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAsElectron microscopy3.12019-06-19
376Y2L|1|L5+ 6Y2L|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in POST stateElectron microscopy32020-04-15
388FL4|1|L3+ 8FL4|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State I3)Electron microscopy2.892023-07-12
396LQM|1|2+ 6LQM|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state CElectron microscopy3.092020-08-26
406Y0G|1|L5+ 6Y0G|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in classical-PRE stateElectron microscopy3.22020-04-15
417BHP|1|L5+ 7BHP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human Ebp1 - 80S ribosomeElectron microscopy3.32021-02-03
426LU8|1|2+ 6LU8|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a human pre-60S ribosomal subunit - state AElectron microscopy3.132020-08-26
436LSR|1|2+ 6LSR|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state BElectron microscopy3.132020-08-26
446LSS|1|2+ 6LSS|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state preAElectron microscopy3.232020-08-26
458FKY|1|L3+ 8FKY|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State F)Electron microscopy2.672023-07-12
466OLI|1|t+ 6OLI|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)Electron microscopy3.52019-06-19
476OLG|1|A2+ 6OLG|1|A3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)Electron microscopy3.42019-06-19
488FKW|1|L3+ 8FKW|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State D2)Electron microscopy2.52023-07-12
498FKV|1|L3+ 8FKV|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State D1)Electron microscopy2.472023-07-12
506Y57|1|L5+ 6Y57|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in hybrid-PRE stateElectron microscopy3.52020-04-15
518FKX|1|L3+ 8FKX|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State E)Electron microscopy2.592023-07-12
525T2C|1|A+ 5T2C|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002CryoEM structure of the human ribosome at 3.6 Angstrom resolutionElectron microscopy3.62017-01-25
538FKZ|1|L3+ 8FKZ|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State G)Electron microscopy3.042023-07-12
546OM7|1|t+ 6OM7|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAsElectron microscopy3.72019-06-19
554UG0|1|L5+ 4UG0|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002STRUCTURE OF THE HUMAN 80S RIBOSOMEElectron microscopy3.62015-06-10
566OLF|1|t+ 6OLF|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAsElectron microscopy3.92019-06-19
576W6L|1|t+ 6W6L|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human ribosome-TMCO1 transloconElectron microscopy3.842020-09-02
588FKU|1|L3+ 8FKU|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State C2)Electron microscopy2.822023-07-12
598FKT|1|L3+ 8FKT|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State C1)Electron microscopy2.812023-07-12
606IP5|1|1A+ 6IP5|1|1CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)Electron microscopy3.92019-05-29
616IP8|1|1A+ 6IP8|1|1CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)Electron microscopy3.92019-05-29
626OLZ|1|A2+ 6OLZ|1|A3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNAElectron microscopy3.92019-06-19
635AJ0|1|A2+ 5AJ0|1|A3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo electron microscopy of actively translating human polysomes (POST state).Electron microscopy3.52015-05-20
648FKS|1|L3+ 8FKS|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State B2)Electron microscopy2.882023-07-12
658FKR|1|L3+ 8FKR|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State B1)Electron microscopy2.892023-07-12
668FKQ|1|L3+ 8FKQ|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State A2)Electron microscopy2.762023-07-12
678FKP|1|L3+ 8FKP|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State A1)Electron microscopy2.852023-07-12
688FL0|1|L3Large subunit ribosomal RNA28S rRNAHomo sapiensEukaryaRF02543Human nucleolar pre-60S ribosomal subunit (State H)Electron microscopy2.912023-07-12
695LKS|1|L5+ 5LKS|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure-function insights reveal the human ribosome as a cancer target for antibioticsElectron microscopy3.62017-04-26
706IP6|1|1A+ 6IP6|1|1CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii)Electron microscopy4.52019-05-29
714V6X|1|A5+ 4V6X|1|A8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of the human 80S ribosomeElectron microscopy52014-07-09
726SXO|1|L5Large subunit ribosomal RNA28S ribosomal RNA including ES27L-B (2839-3265)Homo sapiensEukaryaRF02543Cryo-EM structure of the human Ebp1-ribosome complexElectron microscopy3.32020-02-19
737ZFW|1|L5Large subunit ribosomal RNARNA (615-MER)Homo sapiensEukaryaRF02543Structure of human 80S ribosome obtained from ssDNA coated gridElectron microscopy3.82022-11-23
745A8L|1|ALarge subunit ribosomal RNA28S RIBOSOMAL RNAHomo sapiensEukaryaRF02543Human eRF1 and the hCMV nascent peptide in the translation termination complexElectron microscopy3.82015-12-02

Release history

Release3.2913.2923.2933.294
Date2023-07-122023-07-192023-07-262023-08-02

Parents

This classParent classesRelease idIntersectionAdded to this classOnly in parent
NR_20.0_65061.20NR_20.0_65061.193.291(50) 6QZP|1|L5+6QZP|1|L8, 6LQM|1|2+6LQM|1|8, 6ZM7|1|L5+6ZM7|1|L8, 7XNY|1|L1+7XNY|1|L3, 5A8L|1|A, 6OLE|1|t+6OLE|1|D, 6Y0G|1|L5+6Y0G|1|L8, 7BHP|1|L5+7BHP|1|L8, 8G5Z|1|L5+8G5Z|1|L8, 6IP5|1|1A+6IP5|1|1C, 6OLZ|1|A2+6OLZ|1|A3, 6Z6L|1|L5+6Z6L|1|L8, 7QVP|1|L6+7QVP|1|L1, 8GLP|1|L5+8GLP|1|L8, 4UG0|1|L5+4UG0|1|L8, 6LSR|1|2+6LSR|1|8, 6SXO|1|L5, 6ZME|1|L5+6ZME|1|L8, 8A3D|1|A+8A3D|1|C, 5LKS|1|L5+5LKS|1|L8, 6OLF|1|t+6OLF|1|D, 6Y2L|1|L5+6Y2L|1|L8, 7F5S|1|L5+7F5S|1|L8, 8G61|1|L5+8G61|1|L8, 6OM0|1|t+6OM0|1|D, 6IP8|1|1A+6IP8|1|1C, 6Z6M|1|L5+6Z6M|1|L8, 7XNX|1|L1+7XNX|1|L3, 4V6X|1|A5+4V6X|1|A8, 6LU8|1|2+6LU8|1|8, 6W6L|1|t+6W6L|1|D, 6ZMI|1|L5+6ZMI|1|L8, 8G5Y|1|L5+8G5Y|1|L8, 5T2C|1|A+5T2C|1|C, 6OLI|1|t+6OLI|1|D, 6Y57|1|L5+6Y57|1|L8, 7OW7|1|A+7OW7|1|C, 8G6J|1|L5+8G6J|1|L8, 6Z6N|1|L5+6Z6N|1|L8, 6ZMO|1|L5+6ZMO|1|L8, 5AJ0|1|A2+5AJ0|1|A3, 7QVP|1|L5+7QVP|1|L8, 6IP6|1|1A+6IP6|1|1C, 6LSS|1|2+6LSS|1|8, 7ZFW|1|L5, 8G60|1|L5+8G60|1|L8, 6OLG|1|A2+6OLG|1|A3, 6OM7|1|t+6OM7|1|D, 6XA1|1|L5+6XA1|1|L8, 6Y6X|1|L5+6Y6X|1|L8(24) 8FKT|1|L3+8FKT|1|L1, 8FKZ|1|L3+8FKZ|1|L1, 8FKP|1|L3+8FKP|1|L1, 8FLA|1|L3+8FLA|1|L1, 8FL7|1|L3+8FL7|1|L1, 8FKV|1|L3+8FKV|1|L1, 8FKR|1|L3+8FKR|1|L1, 8FLC|1|L3+8FLC|1|L1, 8FL2|1|L3+8FL2|1|L1, 8FKX|1|L3+8FKX|1|L1, 8FLE|1|L3+8FLE|1|L1, 8FL4|1|L3+8FL4|1|L1, 8FKY|1|L3+8FKY|1|L1, 8FLF|1|L3+8FLF|1|L1, 8FL9|1|L3+8FL9|1|L1, 8FL6|1|L3+8FL6|1|L1, 8FKU|1|L3+8FKU|1|L1, 8FKQ|1|L3+8FKQ|1|L1, 8FLB|1|L3+8FLB|1|L1, 8FL0|1|L3, 8FKW|1|L3+8FKW|1|L1, 8FLD|1|L3+8FLD|1|L1, 8FL3|1|L3+8FL3|1|L1, 8FKS|1|L3+8FKS|1|L1(0)

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. Instances are ordered to put similar structures near each other. The colorbar ranges from 0 to the maximum observed discrepancy, up to 0.5

#S - ordering by similarity (same as in the heat map).
#SPDBTitleMethodResolutionLength
15A8L|1|AHuman eRF1 and the hCMV nascent peptide in the translation termination complexELECTRON MICROSCOPY3.8253
24V6X|1|A5+4V6X|1|A8Structure of the human 80S ribosomeELECTRON MICROSCOPY54298
34UG0|1|L5+4UG0|1|L8STRUCTURE OF THE HUMAN 80S RIBOSOMEELECTRON MICROSCOPY3.63776
45T2C|1|A+5T2C|1|CCryoEM structure of the human ribosome at 3.6 Angstrom resolutionELECTRON MICROSCOPY3.63776
55LKS|1|L5+5LKS|1|L8Structure-function insights reveal the human ribosome as a cancer target for antibioticsELECTRON MICROSCOPY3.63776
65AJ0|1|A2+5AJ0|1|A3Cryo electron microscopy of actively translating human polysomes (POST state).ELECTRON MICROSCOPY3.53612
76OLG|1|A2+6OLG|1|A3Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)ELECTRON MICROSCOPY3.43612
86OLZ|1|A2+6OLZ|1|A3Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNAELECTRON MICROSCOPY3.93643
96OM7|1|t+6OM7|1|DHuman ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAsELECTRON MICROSCOPY3.73607
106OLF|1|t+6OLF|1|DHuman ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAsELECTRON MICROSCOPY3.93607
116OLI|1|t+6OLI|1|DStructure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)ELECTRON MICROSCOPY3.53607
126OLE|1|t+6OLE|1|DHuman ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAsELECTRON MICROSCOPY3.13607
136OM0|1|t+6OM0|1|DHuman ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAsELECTRON MICROSCOPY3.13607
146W6L|1|t+6W6L|1|DCryo-EM structure of the human ribosome-TMCO1 transloconELECTRON MICROSCOPY3.843510
158G61|1|L5+8G61|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)ELECTRON MICROSCOPY2.943528
168G5Y|1|L5+8G5Y|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)ELECTRON MICROSCOPY2.293594
178GLP|1|L5+8GLP|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)ELECTRON MICROSCOPY1.673418
188G5Z|1|L5+8G5Z|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)ELECTRON MICROSCOPY2.643560
198G6J|1|L5+8G6J|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)ELECTRON MICROSCOPY2.83559
206XA1|1|L5+6XA1|1|L8Structure of a drug-like compound stalled human translation termination complexELECTRON MICROSCOPY2.83390
216IP8|1|1A+6IP8|1|1CCryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)ELECTRON MICROSCOPY3.93667
226IP5|1|1A+6IP5|1|1CCryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)ELECTRON MICROSCOPY3.93717
236IP6|1|1A+6IP6|1|1CCryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii)ELECTRON MICROSCOPY4.53667
247BHP|1|L5+7BHP|1|L8Cryo-EM structure of the human Ebp1 - 80S ribosomeELECTRON MICROSCOPY3.33644
257QVP|1|L6+7QVP|1|L1Human collided disome (di-ribosome) stalled on XBP1 mRNAELECTRON MICROSCOPY33572
266Y57|1|L5+6Y57|1|L8Structure of human ribosome in hybrid-PRE stateELECTRON MICROSCOPY3.53574
276QZP|1|L5+6QZP|1|L8High-resolution cryo-EM structure of the human 80S ribosomeELECTRON MICROSCOPY2.93696
287XNX|1|L1+7XNX|1|L3High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cellsELECTRON MICROSCOPY2.73686
297XNY|1|L1+7XNY|1|L3High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsELECTRON MICROSCOPY2.53686
306ZM7|1|L5+6ZM7|1|L8SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complexELECTRON MICROSCOPY2.73773
316ZMI|1|L5+6ZMI|1|L8SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complexELECTRON MICROSCOPY2.63773
326ZMO|1|L5+6ZMO|1|L8SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complexELECTRON MICROSCOPY3.13773
336ZME|1|L5+6ZME|1|L8SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complexELECTRON MICROSCOPY33773
346Z6M|1|L5+6Z6M|1|L8Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1ELECTRON MICROSCOPY3.13772
356Z6L|1|L5+6Z6L|1|L8Cryo-EM structure of human CCDC124 bound to 80S ribosomesELECTRON MICROSCOPY33772
366Z6N|1|L5+6Z6N|1|L8Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)ELECTRON MICROSCOPY2.93772
376Y6X|1|L5+6Y6X|1|L8Tetracenomycin X bound to the human ribosomeELECTRON MICROSCOPY2.83773
386Y0G|1|L5+6Y0G|1|L8Structure of human ribosome in classical-PRE stateELECTRON MICROSCOPY3.23644
397QVP|1|L5+7QVP|1|L8Human collided disome (di-ribosome) stalled on XBP1 mRNAELECTRON MICROSCOPY33611
406Y2L|1|L5+6Y2L|1|L8Structure of human ribosome in POST stateELECTRON MICROSCOPY33613
417F5S|1|L5+7F5S|1|L8human delta-METTL18 60S ribosomeELECTRON MICROSCOPY2.723575
428G60|1|L5+8G60|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)ELECTRON MICROSCOPY2.543509
438A3D|1|A+8A3D|1|CHuman mature large subunit of the ribosome with eIF6 and homoharringtonine boundELECTRON MICROSCOPY1.673190
447OW7|1|A+7OW7|1|CEIF6-bound large subunit of the human ribosomeELECTRON MICROSCOPY2.23190
456LQM|1|2+6LQM|1|8Cryo-EM structure of a pre-60S ribosomal subunit - state CELECTRON MICROSCOPY3.093433
466LSR|1|2+6LSR|1|8Cryo-EM structure of a pre-60S ribosomal subunit - state BELECTRON MICROSCOPY3.133384
476LU8|1|2+6LU8|1|8Cryo-EM structure of a human pre-60S ribosomal subunit - state AELECTRON MICROSCOPY3.133386
486LSS|1|2+6LSS|1|8Cryo-EM structure of a pre-60S ribosomal subunit - state preAELECTRON MICROSCOPY3.233383
498FLF|1|L3+8FLF|1|L1Human nuclear pre-60S ribosomal subunit (State L3)ELECTRON MICROSCOPY2.653219
508FLE|1|L3+8FLE|1|L1Human nuclear pre-60S ribosomal subunit (State L2)ELECTRON MICROSCOPY2.483266
518FLD|1|L3+8FLD|1|L1Human nuclear pre-60S ribosomal subunit (State L1)ELECTRON MICROSCOPY2.583266
528FL7|1|L3+8FL7|1|L1Human nuclear pre-60S ribosomal subunit (State J2)ELECTRON MICROSCOPY2.553306
538FL6|1|L3+8FL6|1|L1Human nuclear pre-60S ribosomal subunit (State J1)ELECTRON MICROSCOPY2.623302
548FLA|1|L3+8FLA|1|L1Human nuclear pre-60S ribosomal subunit (State K1)ELECTRON MICROSCOPY2.633316
558FLB|1|L3+8FLB|1|L1Human nuclear pre-60S ribosomal subunit (State K2)ELECTRON MICROSCOPY2.553316
568FL9|1|L3+8FL9|1|L1Human nuclear pre-60S ribosomal subunit (State J3)ELECTRON MICROSCOPY2.753258
578FLC|1|L3+8FLC|1|L1Human nuclear pre-60S ribosomal subunit (State K3)ELECTRON MICROSCOPY2.763269
588FL4|1|L3+8FL4|1|L1Human nuclear pre-60S ribosomal subunit (State I3)ELECTRON MICROSCOPY2.893361
598FL3|1|L3+8FL3|1|L1Human nuclear pre-60S ribosomal subunit (State I2)ELECTRON MICROSCOPY2.533369
608FL2|1|L3+8FL2|1|L1Human nuclear pre-60S ribosomal subunit (State I1)ELECTRON MICROSCOPY2.673370
618FKZ|1|L3+8FKZ|1|L1Human nucleolar pre-60S ribosomal subunit (State G)ELECTRON MICROSCOPY3.042833
628FKY|1|L3+8FKY|1|L1Human nucleolar pre-60S ribosomal subunit (State F)ELECTRON MICROSCOPY2.672585
638FKX|1|L3+8FKX|1|L1Human nucleolar pre-60S ribosomal subunit (State E)ELECTRON MICROSCOPY2.592250
648FKU|1|L3+8FKU|1|L1Human nucleolar pre-60S ribosomal subunit (State C2)ELECTRON MICROSCOPY2.822185
658FKW|1|L3+8FKW|1|L1Human nucleolar pre-60S ribosomal subunit (State D2)ELECTRON MICROSCOPY2.52277
668FKV|1|L3+8FKV|1|L1Human nucleolar pre-60S ribosomal subunit (State D1)ELECTRON MICROSCOPY2.472213
678FKT|1|L3+8FKT|1|L1Human nucleolar pre-60S ribosomal subunit (State C1)ELECTRON MICROSCOPY2.812125
688FKR|1|L3+8FKR|1|L1Human nucleolar pre-60S ribosomal subunit (State B1)ELECTRON MICROSCOPY2.891767
698FKP|1|L3+8FKP|1|L1Human nucleolar pre-60S ribosomal subunit (State A1)ELECTRON MICROSCOPY2.851507
708FKQ|1|L3+8FKQ|1|L1Human nucleolar pre-60S ribosomal subunit (State A2)ELECTRON MICROSCOPY2.761565
718FKS|1|L3+8FKS|1|L1Human nucleolar pre-60S ribosomal subunit (State B2)ELECTRON MICROSCOPY2.881824
728FL0|1|L3Human nucleolar pre-60S ribosomal subunit (State H)ELECTRON MICROSCOPY2.911558
737ZFW|1|L5Structure of human 80S ribosome obtained from ssDNA coated gridELECTRON MICROSCOPY3.8612
746SXO|1|L5Cryo-EM structure of the human Ebp1-ribosome complexELECTRON MICROSCOPY3.3268
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