Equivalence class NR_20.0_73426.2 Obsolete
| # | IFE | Standardized name | Molecule | Organism | Source | Rfam | Title | Method | Res. Å | Date |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 7Q4O|1|2+ 7Q4O|1|h (rep) | U2 splicesomal small nuclear RNA | BPS oligo, U2 snRNA | Homo sapiens | Eukarya | RF00004 | Substrate-bound A-like U2 snRNP | Electron microscopy | 2.2 | 2022-03-30 |
| 2 | 7Q4P|1|2 | U2 splicesomal small nuclear RNA | U2 snRNA | Homo sapiens | Eukarya | RF00004 | U2 snRNP after ATP-dependent remodelling snRNP | Electron microscopy | 2.2 | 2022-03-30 |
| 3 | 7Q3L|1|2 | U2 splicesomal small nuclear RNA | U2 snRNA | Homo sapiens | Eukarya | RF00004 | Human 17S U2 snRNP 5' domain | Electron microscopy | 2.3 | 2022-03-30 |
| 4 | 6QX9|1|2 | U2 splicesomal small nuclear RNA | AdML pre-mRNA, U2 snRNA, U6 snRNA | Homo sapiens | Eukarya | RF00004 | Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). | Electron microscopy | 3.28 | 2019-04-17 |
| 5 | 6Y50|1|2 | U2 splicesomal small nuclear RNA | U2 snRNA | Homo sapiens | Eukarya | RF00004 | 5'domain of human 17S U2 snRNP | Electron microscopy | 4.1 | 2020-07-01 |
| 6 | 7ABH|1|2 | U2 splicesomal small nuclear RNA | MINX M3 pre-mRNA, U2 snRNA | Homo sapiens | Eukarya | RF00004 | Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion) | Electron microscopy | 4.5 | 2020-12-09 |
| 7 | 5Z58|1|H+ 5Z58|1|F | U2 splicesomal small nuclear RNA + U6 spliceosomal RNA | pre-mRNA, U2 snRNA, U6 snRNA | Homo sapiens | Eukarya | RF00004 + RF00026 | Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom. | Electron microscopy | 4.9 | 2018-09-19 |
| 8 | 5MQF|1|2+ 5MQF|1|6 | U2 splicesomal small nuclear RNA + U6 spliceosomal RNA | Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), small nuclear RNA, Human gene for small nuclear RNA U2 (snRNA U2), MINX pre-mRNA (intron) | Homo sapiens | Eukarya | RF00004 + RF00026 | Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) | Electron microscopy | 5.9 | 2017-03-22 |
| 9 | 5Z56|1|H+ 5Z56|1|F | U2 splicesomal small nuclear RNA + U6 spliceosomal RNA | pre-mRNA, U2 snRNA, U6 snRNA | Homo sapiens | Eukarya | RF00004 + RF00026 | cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom. | Electron microscopy | 5.1 | 2018-09-19 |
| 10 | 6Y5Q|1|2 | U2 splicesomal small nuclear RNA | U2snRNA | Homo sapiens | Eukarya | RF00004 | human 17S U2 snRNP | Electron microscopy | 7.1 | 2020-06-17 |
| 11 | 6Y53|1|2 | U2 splicesomal small nuclear RNA | U2 snRNA | Homo sapiens | Eukarya | RF00004 | human 17S U2 snRNP low resolution part | Electron microscopy | 7.1 | 2020-06-17 |
| 12 | 5Z57|1|H+ 5Z57|1|F | U2 splicesomal small nuclear RNA + U6 spliceosomal RNA | pre-mRNA, U2 snRNA, U6 snRNA | Homo sapiens | Eukarya | RF00004 + RF00026 | Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom | Electron microscopy | 6.5 | 2018-09-19 |
| 13 | 7ABI|1|2+ 7ABI|1|6 | U2 splicesomal small nuclear RNA + U6 spliceosomal RNA | MINX M3 pre-mRNA, U2 snRNA, U6 snRNA | Homo sapiens | Eukarya | RF00004 + RF00026 | Human pre-Bact-2 spliceosome | Electron microscopy | 8 | 2021-02-10 |
Release history
Parents
| This class | Parent classes | Release id | Intersection | Added to this class | Only in parent |
|---|---|---|---|---|---|
| NR_20.0_73426.2 | NR_20.0_73426.1 | 3.224 | (10) 5MQF|1|2+5MQF|1|6, 5Z56|1|H+5Z56|1|F, 5Z57|1|H+5Z57|1|F, 5Z58|1|H+5Z58|1|F, 6QX9|1|2, 6Y50|1|2, 6Y53|1|2, 6Y5Q|1|2, 7ABH|1|2, 7ABI|1|2+7ABI|1|6 | (3) 7Q3L|1|2, 7Q4O|1|2+7Q4O|1|h, 7Q4P|1|2 | (0) |
Children
| This class | Descendant classes | Release id | Intersection | Only in this class | Added to child |
|---|---|---|---|---|---|
| NR_20.0_73426.2 | NR_20.0_73426.3 | 3.242 | (13) 5MQF|1|2+5MQF|1|6, 5Z56|1|H+5Z56|1|F, 5Z57|1|H+5Z57|1|F, 5Z58|1|H+5Z58|1|F, 6QX9|1|2, 6Y50|1|2, 6Y53|1|2, 6Y5Q|1|2, 7ABH|1|2, 7ABI|1|2+7ABI|1|6, 7Q3L|1|2, 7Q4O|1|2+7Q4O|1|h, 7Q4P|1|2 | (0) | (1) 7EVO|1|H |
Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well.
| #S | PDB | Title | Method | Resolution | Length |
|---|---|---|---|---|---|
| 1 | 7Q4P|1|2 | U2 snRNP after ATP-dependent remodelling snRNP | ELECTRON MICROSCOPY | 2.2 | 31 |
| 2 | 7Q4O|1|2+7Q4O|1|h | Substrate-bound A-like U2 snRNP | ELECTRON MICROSCOPY | 2.2 | 24 |
| 3 | 5Z56|1|H+5Z56|1|F | cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom. | ELECTRON MICROSCOPY | 5.1 | 136 |
| 4 | 5Z57|1|H+5Z57|1|F | Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom | ELECTRON MICROSCOPY | 6.5 | 136 |
| 5 | 5Z58|1|H+5Z58|1|F | Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom. | ELECTRON MICROSCOPY | 4.9 | 136 |
| 6 | 7ABI|1|2+7ABI|1|6 | Human pre-Bact-2 spliceosome | ELECTRON MICROSCOPY | 8 | 164 |
| 7 | 7ABH|1|2 | Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion) | ELECTRON MICROSCOPY | 4.5 | 37 |
| 8 | 6QX9|1|2 | Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). | ELECTRON MICROSCOPY | 3.28 | 94 |
| 9 | 7Q3L|1|2 | Human 17S U2 snRNP 5' domain | ELECTRON MICROSCOPY | 2.3 | 41 |
| 10 | 6Y50|1|2 | 5'domain of human 17S U2 snRNP | ELECTRON MICROSCOPY | 4.1 | 50 |
| 11 | 6Y5Q|1|2 | human 17S U2 snRNP | ELECTRON MICROSCOPY | 7.1 | 148 |
| 12 | 6Y53|1|2 | human 17S U2 snRNP low resolution part | ELECTRON MICROSCOPY | 7.1 | 98 |
| 13 | 5MQF|1|2+5MQF|1|6 | Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) | ELECTRON MICROSCOPY | 5.9 | 140 |
Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.
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