Equivalence class NR_20.0_73426.4 Obsolete
| # | IFE | Standardized name | Molecule | Organism | Source | Rfam | Title | Method | Res. Å | Date |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 7EVO|1|H (rep) | U2 splicesomal small nuclear RNA | U2 snRNA | Homo sapiens | Eukarya | RF00004 | The cryo-EM structure of the human 17S U2 snRNP | Electron microscopy | 2.5 | 2022-08-03 |
| 2 | 8HK1|1|H | U2 splicesomal small nuclear RNA | U2 snRNA | Homo sapiens | Eukarya | RF00004 | The cryo-EM structure of human pre-17S U2 snRNP | Electron microscopy | 2.7 | 2023-03-08 |
| 3 | 7Q4O|1|2+ 7Q4O|1|h | U2 splicesomal small nuclear RNA | U2 snRNA, BPS oligo | Homo sapiens | Eukarya | RF00004 | Substrate-bound A-like U2 snRNP | Electron microscopy | 2.2 | 2022-03-30 |
| 4 | 7Q4P|1|2 | U2 splicesomal small nuclear RNA | U2 snRNA | Homo sapiens | Eukarya | RF00004 | U2 snRNP after ATP-dependent remodelling snRNP | Electron microscopy | 2.2 | 2022-03-30 |
| 5 | 7Q3L|1|2 | U2 splicesomal small nuclear RNA | U2 snRNA | Homo sapiens | Eukarya | RF00004 | Human 17S U2 snRNP 5' domain | Electron microscopy | 2.3 | 2022-03-30 |
| 6 | 6QX9|1|2 | U2 splicesomal small nuclear RNA | U2 snRNA, U6 snRNA, AdML pre-mRNA | Homo sapiens | Eukarya | RF00004 | Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). | Electron microscopy | 3.28 | 2019-04-17 |
| 7 | 6Y50|1|2 | U2 splicesomal small nuclear RNA | U2 snRNA | Homo sapiens | Eukarya | RF00004 | 5'domain of human 17S U2 snRNP | Electron microscopy | 4.1 | 2020-07-01 |
| 8 | 7ABH|1|2 | U2 splicesomal small nuclear RNA | U2 snRNA, MINX M3 pre-mRNA | Homo sapiens | Eukarya | RF00004 | Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion) | Electron microscopy | 4.5 | 2020-12-09 |
| 9 | 5Z58|1|H+ 5Z58|1|F | U2 splicesomal small nuclear RNA + U6 spliceosomal RNA | U2 snRNA, U6 snRNA, pre-mRNA | Homo sapiens | Eukarya | RF00004 + RF00026 | Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom. | Electron microscopy | 4.9 | 2018-09-19 |
| 10 | 5MQF|1|2+ 5MQF|1|6 | U2 splicesomal small nuclear RNA + U6 spliceosomal RNA | Human gene for small nuclear RNA U2 (snRNA U2), Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), small nuclear RNA, MINX pre-mRNA (intron) | Homo sapiens | Eukarya | RF00004 + RF00026 | Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) | Electron microscopy | 5.9 | 2017-03-22 |
| 11 | 5Z56|1|H+ 5Z56|1|F | U2 splicesomal small nuclear RNA + U6 spliceosomal RNA | U2 snRNA, U6 snRNA, pre-mRNA | Homo sapiens | Eukarya | RF00004 + RF00026 | cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom. | Electron microscopy | 5.1 | 2018-09-19 |
| 12 | 6Y5Q|1|2 | U2 splicesomal small nuclear RNA | U2snRNA | Homo sapiens | Eukarya | RF00004 | human 17S U2 snRNP | Electron microscopy | 7.1 | 2020-06-17 |
| 13 | 6Y53|1|2 | U2 splicesomal small nuclear RNA | U2 snRNA | Homo sapiens | Eukarya | RF00004 | human 17S U2 snRNP low resolution part | Electron microscopy | 7.1 | 2020-06-17 |
| 14 | 5Z57|1|H+ 5Z57|1|F | U2 splicesomal small nuclear RNA + U6 spliceosomal RNA | U2 snRNA, U6 snRNA, pre-mRNA | Homo sapiens | Eukarya | RF00004 + RF00026 | Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom | Electron microscopy | 6.5 | 2018-09-19 |
| 15 | 7ABI|1|2+ 7ABI|1|6 | U2 splicesomal small nuclear RNA + U6 spliceosomal RNA | U2 snRNA, U6 snRNA, MINX M3 pre-mRNA | Homo sapiens | Eukarya | RF00004 + RF00026 | Human pre-Bact-2 spliceosome | Electron microscopy | 8 | 2021-02-10 |
Release history
Parents
| This class | Parent classes | Release id | Intersection | Added to this class | Only in parent |
|---|---|---|---|---|---|
| NR_20.0_73426.4 | NR_20.0_73426.3 | 3.273 | (14) 7Q4P|1|2, 7Q4O|1|2+7Q4O|1|h, 7Q3L|1|2, 7EVO|1|H, 7ABI|1|2+7ABI|1|6, 7ABH|1|2, 6Y5Q|1|2, 6Y53|1|2, 6Y50|1|2, 6QX9|1|2, 5Z58|1|H+5Z58|1|F, 5Z57|1|H+5Z57|1|F, 5Z56|1|H+5Z56|1|F, 5MQF|1|2+5MQF|1|6 | (1) 8HK1|1|H | (0) |
Children
| This class | Descendant classes | Release id | Intersection | Only in this class | Added to child |
|---|---|---|---|---|---|
| NR_20.0_73426.4 | NR_20.0_73426.5 | 3.281 | (15) 6Y50|1|2, 7Q4P|1|2, 6QX9|1|2, 7Q4O|1|2+7Q4O|1|h, 5Z58|1|H+5Z58|1|F, 7Q3L|1|2, 5Z57|1|H+5Z57|1|F, 7EVO|1|H, 5Z56|1|H+5Z56|1|F, 7ABI|1|2+7ABI|1|6, 5MQF|1|2+5MQF|1|6, 7ABH|1|2, 6Y5Q|1|2, 6Y53|1|2, 8HK1|1|H | (0) | (2) 7ONB|1|H, 7VPX|1|H |
Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. Instances are ordered to put similar structures near each other. The colorbar ranges from 0 to the maximum observed discrepancy, up to 0.5
#S - ordering by similarity (same as in the heat map).| #S | PDB | Title | Method | Resolution | Length |
|---|---|---|---|---|---|
| 1 | 5MQF|1|2+5MQF|1|6 | Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) | ELECTRON MICROSCOPY | 5.9 | 140 |
| 2 | 6Y53|1|2 | human 17S U2 snRNP low resolution part | ELECTRON MICROSCOPY | 7.1 | 98 |
| 3 | 7EVO|1|H | The cryo-EM structure of the human 17S U2 snRNP | ELECTRON MICROSCOPY | 2.5 | 148 |
| 4 | 8HK1|1|H | The cryo-EM structure of human pre-17S U2 snRNP | ELECTRON MICROSCOPY | 2.7 | 148 |
| 5 | 6Y5Q|1|2 | human 17S U2 snRNP | ELECTRON MICROSCOPY | 7.1 | 148 |
| 6 | 6Y50|1|2 | 5'domain of human 17S U2 snRNP | ELECTRON MICROSCOPY | 4.1 | 50 |
| 7 | 7Q3L|1|2 | Human 17S U2 snRNP 5' domain | ELECTRON MICROSCOPY | 2.3 | 41 |
| 8 | 6QX9|1|2 | Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). | ELECTRON MICROSCOPY | 3.28 | 94 |
| 9 | 7ABH|1|2 | Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion) | ELECTRON MICROSCOPY | 4.5 | 37 |
| 10 | 7ABI|1|2+7ABI|1|6 | Human pre-Bact-2 spliceosome | ELECTRON MICROSCOPY | 8 | 164 |
| 11 | 5Z57|1|H+5Z57|1|F | Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom | ELECTRON MICROSCOPY | 6.5 | 136 |
| 12 | 5Z56|1|H+5Z56|1|F | cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom. | ELECTRON MICROSCOPY | 5.1 | 136 |
| 13 | 5Z58|1|H+5Z58|1|F | Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom. | ELECTRON MICROSCOPY | 4.9 | 136 |
| 14 | 7Q4O|1|2+7Q4O|1|h | Substrate-bound A-like U2 snRNP | ELECTRON MICROSCOPY | 2.2 | 24 |
| 15 | 7Q4P|1|2 | U2 snRNP after ATP-dependent remodelling snRNP | ELECTRON MICROSCOPY | 2.2 | 31 |
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