#PDBTitleRNA source organismCompoundsMethodResolutionDate
12D2K|1|D+2D2K|1|C+2D2K|1|A+2D2K|1|B (rep)Crystal Structure of a minimal, native (U39) all-RNA hairpin ribozyme5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*UP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'X-RAY DIFFRACTION2.652005-11-01
23I2R|1|CCrystal structure of the hairpin ribozyme with a 2',5'-linked substrate with N1-deazaadenosine at position A95'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', DNA/RNA (30-MER), 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'X-RAY DIFFRACTION2.82009-11-03
33I2U|1|CCrystal structure of the haiprin ribozyme with a 2',5'-linked substrate and N1-deazaadenosine at position A105'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', DNA/RNA (30-MER), 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'X-RAY DIFFRACTION2.82009-11-03
43I2Q|1|CCrystal structure of the hairpin ribozyme with 2'OMe substrate strand and N1-deazaadenosine at position A95'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', DNA/RNA (30-MER), 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'X-RAY DIFFRACTION2.92009-11-03
53CQS|1|CA 3'-OH, 2',5'-phosphodiester substitution in the hairpin ribozyme active site reveals similarities with protein ribonucleases13-mer substrate strand with 3'-OH, 2',5'-phosphodiester covalently linking 5th and 6th nucleotides, 29-mer ribozyme strand with S9L synthetic linker at 13th position, 19-mer ribozyme strandX-RAY DIFFRACTION2.82008-05-20
63CR1|1|Ccrystal structure of a minimal, mutant, all-RNA hairpin ribozyme (A38C, A-1OMA) grown from MgCl2RNA (5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3'), loop A and B ribozyme strand, RNA (5'-R(*UP*CP*GP*UP*GP*GP*UP*CP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3')X-RAY DIFFRACTION2.252008-08-26
73I2S|1|CCrystal structure of the hairpin ribozyme with a 2'OMe substrate and N1-deazaadenosine at position A105'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', DNA/RNA (30-MER), 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'X-RAY DIFFRACTION2.752009-11-03
83GS8|1|D+3GS8|1|C+3GS8|1|A+3GS8|1|BAn all-RNA hairpin ribozyme A38N1dA38 variant with a transition-state mimic substrate strandRNA (5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3'), RNA (5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3'), RNA (5'-R(P*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3'), RNA (5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3')X-RAY DIFFRACTION2.852009-04-21
91ZFV|1|D+1ZFV|1|C+1ZFV|1|A+1ZFV|1|BThe structure of an all-RNA minimal Hairpin Ribozyme with Mutation G8A at the cleavage site5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*CP*GP*GP*UP*GP*AP*AP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'X-RAY DIFFRACTION2.42006-02-14
104G6R|1|D+4G6R|1|C+4G6R|1|A+4G6R|1|BMinimal Hairpin Ribozyme in the Transition State with G8I VariationLoop A Substrate strand, Loop A Ribozyme strand, Loop B Ribozyme Strand, Loop B S-turn strandX-RAY DIFFRACTION2.832012-08-15
112P7D|1|D+2P7D|1|C+2P7D|1|PA Minimal, 'Hinged' Hairpin Ribozyme Construct Solved with Mimics of the Product Strands at 2.25 Angstroms Resolution5' substrate strand, pentameric fragment, Ribozyme strand I, Ribozyme strand II, Ribozyme strand III, 3' substrate strand, octameric fragmentX-RAY DIFFRACTION2.252007-05-22
121X9K|1|D+1X9K|1|C+1X9K|1|A+1X9K|1|BAn all-RNA Hairpin Ribozyme with mutation U39C5'-R(*UP*CP*GP*CP*AP*GP*UP*CP*CP*UP*AP*UP*U)-3', 5'-R(*AP*AP*UP*AP*GP*AP*GP*AP*AP*GP*CP*GP*A)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'X-RAY DIFFRACTION3.172005-11-22
132NPZ|1|D+2NPZ|1|C+2NPZ|1|A+2NPZ|1|BCrystal structure of junctioned hairpin ribozyme incorporating synthetic propyl linker5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'X-RAY DIFFRACTION3.352007-08-14
141X9C|1|D+1X9C|1|C+1X9C|1|A+1X9C|1|BAn all-RNA Hairpin Ribozyme with mutation U39C5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'X-RAY DIFFRACTION2.192005-11-22
153GS1|1|D+3GS1|1|C+3GS1|1|A+3GS1|1|BAn all-RNA Hairpin Ribozyme with mutation A38N1dARNA (5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3'), RNA (5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3'), RNA (5'-R(P*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3'), RNA (5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3')X-RAY DIFFRACTION2.852009-05-12
162BCZ|1|D+2BCZ|1|C+2BCZ|1|A+2BCZ|1|BCrystal Structure of a minimal, mutant all-RNA hairpin ribozyme (U39C, G8I, 2'deoxy A-1)5'-R(*UP*CP*CP*CP*(DA)P*GP*UP*CP*CP*AP*CP*CP*G)-3'), 5'-R(*CP*GP*GP*UP*GP*AP*IP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'X-RAY DIFFRACTION2.42006-02-14
172NPY|1|D+2NPY|1|C+2NPY|1|A+2NPY|1|BCrystal Structure of a junctioned hairpin ribozyme incorporating 9atom linker and 2'-deoxy 2'-amino U at A-15'-R(*UP*CP*CP*CP*(U2N)P*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'X-RAY DIFFRACTION2.652007-08-14
182OUE|1|D+2OUE|1|C+2OUE|1|A+2OUE|1|BCrystal structure of a junctionless all-RNA hairpin ribozyme at 2.05 angstroms resolutionSubstrate strand - Minimal Junctionless Hairpin Ribozyme, Loop A ribozyme strand, Loop B ribozyme strand, Loop B S-turn strandX-RAY DIFFRACTION2.052007-03-06
192BCY|1|D+2BCY|1|C+2BCY|1|A+2BCY|1|BCrystal Structure of a minimal, mutant all-RNA hairpin ribozyme (U39C, G8MTU)5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*CP*GP*GP*UP*GP*AP*(MTU)P*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'X-RAY DIFFRACTION2.72006-02-14
201ZFT|1|D+1ZFT|1|C+1ZFT|1|A+1ZFT|1|BThe crystal structure of an all-RNA minimal Hairpin Ribozyme with mutant G8I at the cleavage site5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*CP*GP*GP*UP*GP*AP*IP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'X-RAY DIFFRACTION2.332006-02-14
212FGP|1|D+2FGP|1|C+2FGP|1|A+2FGP|1|BCrystal structure of a minimal, all RNA hairpin ribozyme with modifications (g8dap, u39c) at ph 8.65'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*CP*GP*GP*UP*GP*AP*(N6G)P*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C) -3'X-RAY DIFFRACTION2.42006-02-14
221ZFX|1|D+1ZFX|1|C+1ZFX|1|A+1ZFX|1|BThe Structure of a minimal all-RNA Hairpin Ribozyme with the mutant G8U at the cleavage site5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*CP*GP*GP*UP*GP*AP*UP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'X-RAY DIFFRACTION2.382006-02-14
232P7F|1|D+2P7F|1|C+2P7F|1|A+2P7F|1|BThe Novel Use of a 2',5'-Phosphodiester Linkage as a Reaction Intermediate at the Active Site of a Small Ribozymesubstrate strand, Loop A ribozyme strand, Loop B ribozyme strand, Loop B S-turn strandX-RAY DIFFRACTION2.352007-05-22
242P7E|1|D+2P7E|1|C+2P7E|1|PVanadate at the Active Site of a Small Ribozyme Suggests a Role for Water in Transition-State Stabilization5' substrate strand, pentameric fragment, Ribozyme strand I, Ribozyme strand II, Ribozyme strand III, 3' substrate strand, octameric fragmentX-RAY DIFFRACTION2.052007-05-22
252D2L|1|D+2D2L|1|C+2D2L|1|A+2D2L|1|BCrystal Structure of a minimal, all-RNA hairpin ribozyme with a propyl linker (C3) at position U395'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*(P1P)P*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3'X-RAY DIFFRACTION2.52005-11-01

Release history

Release2.02.12.22.32.42.52.62.72.82.92.102.112.122.132.142.152.162.172.182.192.202.212.222.232.242.252.262.272.282.292.302.312.322.332.342.352.362.372.382.392.402.412.422.432.442.452.462.472.482.492.502.512.522.532.542.552.562.572.582.592.602.612.622.632.642.652.662.672.682.692.702.712.722.732.742.752.762.772.782.792.802.812.822.832.842.852.862.872.882.892.902.912.922.932.942.952.962.972.982.992.1002.1012.1022.1032.1042.1052.1062.1072.1082.1092.1102.1112.1122.1132.1142.1152.1162.1172.1182.1192.1202.1212.1222.1232.1242.1252.1262.1272.1282.1292.1302.1312.1322.1332.1342.1352.1362.1372.1382.1392.1402.1412.1422.1432.1442.1452.146
Date2014-12-052014-12-122014-12-192014-12-262015-01-022015-01-092015-01-162015-01-232015-01-302015-02-062015-02-132015-02-202015-02-272015-03-062015-03-132015-03-202015-03-272015-04-032015-04-102015-04-172015-04-242015-05-012015-05-082015-05-152015-05-222015-05-292015-06-052015-06-122015-06-192015-06-262015-07-032015-07-102015-07-172015-07-242015-07-312015-08-072015-08-142015-08-212015-08-282015-09-042015-09-112015-09-182015-09-252015-10-022015-10-092015-10-162015-10-232015-10-302015-11-062015-11-132015-11-202015-11-272015-12-042015-12-112015-12-182015-12-252016-01-012016-01-082016-01-152016-01-222016-01-292016-02-052016-02-122016-02-192016-02-262016-03-042016-03-112016-03-182016-03-252016-04-012016-04-082016-04-152016-04-222016-04-292016-05-062016-05-132016-05-202016-05-272016-06-032016-06-102016-06-172016-06-242016-07-012016-07-082016-07-152016-07-222016-07-292016-08-052016-08-122016-08-192016-08-262016-09-022016-09-092016-09-162016-09-232016-09-302016-10-072016-10-142016-10-212016-10-282016-11-042016-11-112016-11-182016-11-252016-12-022016-12-092016-12-162016-12-232016-12-302017-01-062017-01-132017-01-202017-01-272017-02-032017-02-102017-02-172017-02-242017-03-032017-03-102017-03-172017-03-242017-03-312017-04-112017-04-152017-04-262017-04-292017-05-092017-05-152017-05-202017-05-272017-06-072017-06-112017-06-212017-06-242017-06-282017-07-042017-07-102017-07-152017-07-262017-07-312017-08-052017-08-122017-08-192017-08-262017-09-032017-09-092017-09-16

Parents

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Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. Instances are ordered to put similar structures near each other. The colorbar ranges from 0 to the maximum observed discrepancy, up to 0.5

#S - ordering by similarity (same as in the heat map).
#SPDBTitleMethodResolutionLength
12D2K|1|D+2D2K|1|C+2D2K|1|A+2D2K|1|BCrystal Structure of a minimal, native (U39) all-RNA hairpin ribozymeX-RAY DIFFRACTION2.6522
23I2R|1|CCrystal structure of the hairpin ribozyme with a 2',5'-linked substrate with N1-deazaadenosine at position A9X-RAY DIFFRACTION2.819
33I2U|1|CCrystal structure of the haiprin ribozyme with a 2',5'-linked substrate and N1-deazaadenosine at position A10X-RAY DIFFRACTION2.819
43I2Q|1|CCrystal structure of the hairpin ribozyme with 2'OMe substrate strand and N1-deazaadenosine at position A9X-RAY DIFFRACTION2.919
53CQS|1|CA 3'-OH, 2',5'-phosphodiester substitution in the hairpin ribozyme active site reveals similarities with protein ribonucleasesX-RAY DIFFRACTION2.819
63CR1|1|Ccrystal structure of a minimal, mutant, all-RNA hairpin ribozyme (A38C, A-1OMA) grown from MgCl2X-RAY DIFFRACTION2.2519
73I2S|1|CCrystal structure of the hairpin ribozyme with a 2'OMe substrate and N1-deazaadenosine at position A10X-RAY DIFFRACTION2.7519
83GS8|1|D+3GS8|1|C+3GS8|1|A+3GS8|1|BAn all-RNA hairpin ribozyme A38N1dA38 variant with a transition-state mimic substrate strandX-RAY DIFFRACTION2.8519
91ZFV|1|D+1ZFV|1|C+1ZFV|1|A+1ZFV|1|BThe structure of an all-RNA minimal Hairpin Ribozyme with Mutation G8A at the cleavage siteX-RAY DIFFRACTION2.419
104G6R|1|D+4G6R|1|C+4G6R|1|A+4G6R|1|BMinimal Hairpin Ribozyme in the Transition State with G8I VariationX-RAY DIFFRACTION2.8319
112P7D|1|D+2P7D|1|C+2P7D|1|PA Minimal, 'Hinged' Hairpin Ribozyme Construct Solved with Mimics of the Product Strands at 2.25 Angstroms ResolutionX-RAY DIFFRACTION2.2519
121X9K|1|D+1X9K|1|C+1X9K|1|A+1X9K|1|BAn all-RNA Hairpin Ribozyme with mutation U39CX-RAY DIFFRACTION3.1719
132NPZ|1|D+2NPZ|1|C+2NPZ|1|A+2NPZ|1|BCrystal structure of junctioned hairpin ribozyme incorporating synthetic propyl linkerX-RAY DIFFRACTION3.3519
141X9C|1|D+1X9C|1|C+1X9C|1|A+1X9C|1|BAn all-RNA Hairpin Ribozyme with mutation U39CX-RAY DIFFRACTION2.1919
153GS1|1|D+3GS1|1|C+3GS1|1|A+3GS1|1|BAn all-RNA Hairpin Ribozyme with mutation A38N1dAX-RAY DIFFRACTION2.8519
162BCZ|1|D+2BCZ|1|C+2BCZ|1|A+2BCZ|1|BCrystal Structure of a minimal, mutant all-RNA hairpin ribozyme (U39C, G8I, 2'deoxy A-1)X-RAY DIFFRACTION2.419
172NPY|1|D+2NPY|1|C+2NPY|1|A+2NPY|1|BCrystal Structure of a junctioned hairpin ribozyme incorporating 9atom linker and 2'-deoxy 2'-amino U at A-1X-RAY DIFFRACTION2.6519
182OUE|1|D+2OUE|1|C+2OUE|1|A+2OUE|1|BCrystal structure of a junctionless all-RNA hairpin ribozyme at 2.05 angstroms resolutionX-RAY DIFFRACTION2.0519
192BCY|1|D+2BCY|1|C+2BCY|1|A+2BCY|1|BCrystal Structure of a minimal, mutant all-RNA hairpin ribozyme (U39C, G8MTU)X-RAY DIFFRACTION2.719
201ZFT|1|D+1ZFT|1|C+1ZFT|1|A+1ZFT|1|BThe crystal structure of an all-RNA minimal Hairpin Ribozyme with mutant G8I at the cleavage siteX-RAY DIFFRACTION2.3319
212FGP|1|D+2FGP|1|C+2FGP|1|A+2FGP|1|BCrystal structure of a minimal, all RNA hairpin ribozyme with modifications (g8dap, u39c) at ph 8.6X-RAY DIFFRACTION2.419
221ZFX|1|D+1ZFX|1|C+1ZFX|1|A+1ZFX|1|BThe Structure of a minimal all-RNA Hairpin Ribozyme with the mutant G8U at the cleavage siteX-RAY DIFFRACTION2.3819
232P7F|1|D+2P7F|1|C+2P7F|1|A+2P7F|1|BThe Novel Use of a 2',5'-Phosphodiester Linkage as a Reaction Intermediate at the Active Site of a Small RibozymeX-RAY DIFFRACTION2.3519
242P7E|1|D+2P7E|1|C+2P7E|1|PVanadate at the Active Site of a Small Ribozyme Suggests a Role for Water in Transition-State StabilizationX-RAY DIFFRACTION2.0519
252D2L|1|D+2D2L|1|C+2D2L|1|A+2D2L|1|BCrystal Structure of a minimal, all-RNA hairpin ribozyme with a propyl linker (C3) at position U39X-RAY DIFFRACTION2.518