#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. ÅDate
16QW6|1|5 (rep)U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution.Electron microscopy2.922019-04-17
26QX9|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).Electron microscopy3.282019-04-17
36QDV|1|5U5 spliceosomal RNALigated exons: MINX mRNA, U5 snRNAHomo sapiensEukaryaRF00020Human post-catalytic P complex spliceosomeElectron microscopy3.32019-02-20
46ZYM|1|5U5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Human C Complex Spliceosome - High-resolution COREElectron microscopy3.42020-10-14
56ICZ|1|BU5 spliceosomal RNApre-mRNA, U5snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstromElectron microscopy32019-03-13
66FF4|1|5U5 spliceosomal RNApre mRNA, U2 snRNA, U5 snRNAHomo sapiensEukaryaRF00020human Bact spliceosome core structureElectron microscopy3.42018-08-29
76ID0|1|BU5 spliceosomal RNAU5snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolutionElectron microscopy2.92019-03-13
85XJC|1|BU5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstromElectron microscopy3.62017-07-05
96ID1|1|BU5 spliceosomal RNAU5snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolutionElectron microscopy2.862019-03-13
107AAV|1|5U5 spliceosomal RNAMINX M3 pre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Human pre-Bact-2 spliceosome core structureElectron microscopy4.22020-12-09
115YZG|1|BU5 spliceosomal RNAPre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolutionElectron microscopy4.12018-08-08
126AHD|1|BU5 spliceosomal RNApre-mRNA, U5snRNAHomo sapiensEukaryaRF00020The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolutionElectron microscopy3.82018-11-14
135O9Z|1|5U5 spliceosomal RNAHomo sapiens U5 A small nuclear RNA, MINX pre-mRNAHomo sapiensEukaryaRF00020Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex)Electron microscopy4.52017-08-16
146FF7|1|5U5 spliceosomal RNApre-mRNA, U2 snRNA, U5 snRNAHomo sapiensEukaryaRF00020human Bact spliceosome core structureElectron microscopy4.52019-03-13
157ABF|1|5U5 spliceosomal RNAMINX M3 RNA, U5 small nuclear RNAHomo sapiensEukaryaRF00020Human pre-Bact-1 spliceosome core structureElectron microscopy3.92020-12-09
165Z58|1|BU5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom.Electron microscopy4.92018-09-19
177A5P|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Human C Complex Spliceosome - Medium-resolution PERIPHERYElectron microscopy52020-10-14
185Z56|1|BU5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom.Electron microscopy5.12018-09-19
196AH0|1|BU5 spliceosomal RNAU5snRNAHomo sapiensEukaryaRF00020The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex)Electron microscopy5.72018-11-14
205MQF|1|5U5 spliceosomal RNAHomo sapiens U5 A small nuclear RNA, MINX pre-mRNA (intron)Homo sapiensEukaryaRF00020Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex)Electron microscopy5.92017-03-22
215Z57|1|BU5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstromElectron microscopy6.52018-09-19
223JCR|1|HU5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF000203D structure determination of the human*U4/U6.U5* tri-snRNP complexElectron microscopy72016-03-09

Release history

Release3.1563.157
Date2020-12-092020-12-16

Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.

#SViewPDBTitleMethodResolutionLength
15Z58|1|BCryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom.ELECTRON MICROSCOPY4.984
25Z57|1|BCryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstromELECTRON MICROSCOPY6.584
35Z56|1|Bcryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom.ELECTRON MICROSCOPY5.184
45YZG|1|BThe Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolutionELECTRON MICROSCOPY4.184
55XJC|1|BCryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstromELECTRON MICROSCOPY3.684
66ID1|1|BCryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolutionELECTRON MICROSCOPY2.8698
76ID0|1|BCryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolutionELECTRON MICROSCOPY2.998
86ICZ|1|BCryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstromELECTRON MICROSCOPY397
97ABF|1|5Human pre-Bact-1 spliceosome core structureELECTRON MICROSCOPY3.958
107AAV|1|5Human pre-Bact-2 spliceosome core structureELECTRON MICROSCOPY4.269
116FF7|1|5human Bact spliceosome core structureELECTRON MICROSCOPY4.570
126FF4|1|5human Bact spliceosome core structureELECTRON MICROSCOPY3.470
136ZYM|1|5Human C Complex Spliceosome - High-resolution COREELECTRON MICROSCOPY3.474
146QDV|1|5Human post-catalytic P complex spliceosomeELECTRON MICROSCOPY3.375
156QX9|1|5Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).ELECTRON MICROSCOPY3.28104
166QW6|1|5Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution.ELECTRON MICROSCOPY2.92104
176AHD|1|BThe Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolutionELECTRON MICROSCOPY3.8115
186AH0|1|BThe Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex)ELECTRON MICROSCOPY5.7115
195O9Z|1|5Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex)ELECTRON MICROSCOPY4.5114
205MQF|1|5Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex)ELECTRON MICROSCOPY5.9114
217A5P|1|5Human C Complex Spliceosome - Medium-resolution PERIPHERYELECTRON MICROSCOPY540
223JCR|1|H3D structure determination of the human*U4/U6.U5* tri-snRNP complexELECTRON MICROSCOPY763

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


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