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Equivalence class NR_20.0_73426.8 Obsolete

#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. ÅDate
17EVO|1|H (rep)U2 splicesomal small nuclear RNAU2 snRNAHomo sapiensEukaryaRF00004The cryo-EM structure of the human 17S U2 snRNPElectron microscopy2.52022-08-03
28HK1|1|HU2 splicesomal small nuclear RNAU2 snRNAHomo sapiensEukaryaRF00004The cryo-EM structure of human pre-17S U2 snRNPElectron microscopy2.72023-03-08
38H6L|1|2AU2 splicesomal small nuclear RNApre-mRNA, U2 snRNA, U6 snRNAHomo sapiensEukaryaRF00004Cryo-EM structure of human exon-defined spliceosome in the early B state.Electron microscopy2.62024-05-01
47Q4O|1|2+ 7Q4O|1|hU2 splicesomal small nuclear RNABPS oligo, U2 snRNAHomo sapiensEukaryaRF00004Substrate-bound A-like U2 snRNPElectron microscopy2.22022-03-30
58H6K|1|2AU2 splicesomal small nuclear RNApre-mRNA, U2 snRNA, U6 snRNAHomo sapiensEukaryaRF00004Cryo-EM structure of human exon-defined spliceosome in the mature B state.Electron microscopy2.72024-05-01
67Q4P|1|2U2 splicesomal small nuclear RNAU2 snRNAHomo sapiensEukaryaRF00004U2 snRNP after ATP-dependent remodelling snRNPElectron microscopy2.22022-03-30
77Q3L|1|2U2 splicesomal small nuclear RNAU2 snRNAHomo sapiensEukaryaRF00004Human 17S U2 snRNP 5' domainElectron microscopy2.32022-03-30
87VPX|1|HU2 splicesomal small nuclear RNApre-mRNA, U2 snRNAHomo sapiensEukaryaRF00004The cryo-EM structure of the human pre-A complexElectron microscopy32023-05-03
98H6E|1|2AU2 splicesomal small nuclear RNApre-mRNA, U2 snRNA, U6 snRNAHomo sapiensEukaryaRF00004Cryo-EM structure of human exon-defined spliceosome in the late pre-B state.Electron microscopy3.22024-05-01
108H6J|1|2AU2 splicesomal small nuclear RNApre-mRNA, U2 snRNA, U6 snRNAHomo sapiensEukaryaRF00004Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state.Electron microscopy3.252024-05-01
116QX9|1|2U2 splicesomal small nuclear RNAAdML pre-mRNA, U2 snRNA, U6 snRNAHomo sapiensEukaryaRF00004Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).Electron microscopy3.282019-04-17
127ONB|1|HU2 splicesomal small nuclear RNAMINX, RNU2Homo sapiensEukaryaRF00004Structure of the U2 5' module of the A3'-SSA complexElectron microscopy3.12021-08-04
136Y50|1|2U2 splicesomal small nuclear RNAU2 snRNAHomo sapiensEukaryaRF000045'domain of human 17S U2 snRNPElectron microscopy4.12020-07-01
147ABH|1|2U2 splicesomal small nuclear RNAMINX M3 pre-mRNA, U2 snRNAHomo sapiensEukaryaRF00004Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion)Electron microscopy4.52020-12-09
158QO9|1|2U2 splicesomal small nuclear RNAU2 snRNAHomo sapiensEukaryaRF00004Cryo-EM structure of a human spliceosomal B complex protomerElectron microscopy5.292024-01-24
168CH6|1|f+ 8CH6|1|dU2 splicesomal small nuclear RNA + U6 spliceosomal RNAMINX-M3, RNU2-1, RNU6-1Homo sapiensEukaryaRF00004 + RF00026Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).Electron microscopy5.92023-05-10
175Z58|1|H+ 5Z58|1|FU2 splicesomal small nuclear RNA + U6 spliceosomal RNApre-mRNA, U2 snRNA, U6 snRNAHomo sapiensEukaryaRF00004 + RF00026Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom.Electron microscopy4.92018-09-19
185MQF|1|2+ 5MQF|1|6U2 splicesomal small nuclear RNA + U6 spliceosomal RNAHomo sapiens RNA, U6 small nuclear 1 (RNU6-1), small nuclear RNA, Human gene for small nuclear RNA U2 (snRNA U2), MINX pre-mRNA (intron)Homo sapiensEukaryaRF00004 + RF00026Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex)Electron microscopy5.92017-03-22
195Z56|1|H+ 5Z56|1|FU2 splicesomal small nuclear RNA + U6 spliceosomal RNApre-mRNA, U2 snRNA, U6 snRNAHomo sapiensEukaryaRF00004 + RF00026cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom.Electron microscopy5.12018-09-19
206Y5Q|1|2U2 splicesomal small nuclear RNAU2snRNAHomo sapiensEukaryaRF00004human 17S U2 snRNPElectron microscopy7.12020-06-17
216Y53|1|2U2 splicesomal small nuclear RNAU2 snRNAHomo sapiensEukaryaRF00004human 17S U2 snRNP low resolution partElectron microscopy7.12020-06-17
225Z57|1|H+ 5Z57|1|FU2 splicesomal small nuclear RNA + U6 spliceosomal RNApre-mRNA, U2 snRNA, U6 snRNAHomo sapiensEukaryaRF00004 + RF00026Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstromElectron microscopy6.52018-09-19
237ABI|1|2+ 7ABI|1|6U2 splicesomal small nuclear RNA + U6 spliceosomal RNAMINX M3 pre-mRNA, U2 snRNA, U6 snRNAHomo sapiensEukaryaRF00004 + RF00026Human pre-Bact-2 spliceosomeElectron microscopy82021-02-10

Release history

Release3.3333.3343.3353.3363.3373.338
Date2024-05-012024-05-082024-05-152024-05-222024-05-292024-06-05

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Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.

#SViewPDBTitleMethodResolutionLength
17Q4P|1|2U2 snRNP after ATP-dependent remodelling snRNPELECTRON MICROSCOPY2.231
27Q4O|1|2+ 7Q4O|1|hSubstrate-bound A-like U2 snRNPELECTRON MICROSCOPY2.224
38QO9|1|2Cryo-EM structure of a human spliceosomal B complex protomerELECTRON MICROSCOPY5.2998
48H6L|1|2ACryo-EM structure of human exon-defined spliceosome in the early B state.ELECTRON MICROSCOPY2.6109
58H6K|1|2ACryo-EM structure of human exon-defined spliceosome in the mature B state.ELECTRON MICROSCOPY2.7109
68H6E|1|2ACryo-EM structure of human exon-defined spliceosome in the late pre-B state.ELECTRON MICROSCOPY3.2109
78H6J|1|2ACryo-EM structure of human exon-defined spliceosome in the mature pre-B state.ELECTRON MICROSCOPY3.25109
87ABH|1|2Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion)ELECTRON MICROSCOPY4.537
98CH6|1|f+ 8CH6|1|dStructure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).ELECTRON MICROSCOPY5.9137
105Z58|1|H+ 5Z58|1|FCryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom.ELECTRON MICROSCOPY4.9136
115Z57|1|H+ 5Z57|1|FCryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstromELECTRON MICROSCOPY6.5136
125Z56|1|H+ 5Z56|1|Fcryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom.ELECTRON MICROSCOPY5.1136
137ABI|1|2+ 7ABI|1|6Human pre-Bact-2 spliceosomeELECTRON MICROSCOPY8164
147VPX|1|HThe cryo-EM structure of the human pre-A complexELECTRON MICROSCOPY3130
157ONB|1|HStructure of the U2 5' module of the A3'-SSA complexELECTRON MICROSCOPY3.132
166QX9|1|2Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).ELECTRON MICROSCOPY3.2894
177Q3L|1|2Human 17S U2 snRNP 5' domainELECTRON MICROSCOPY2.341
186Y50|1|25'domain of human 17S U2 snRNPELECTRON MICROSCOPY4.150
196Y5Q|1|2human 17S U2 snRNPELECTRON MICROSCOPY7.1148
208HK1|1|HThe cryo-EM structure of human pre-17S U2 snRNPELECTRON MICROSCOPY2.7148
217EVO|1|HThe cryo-EM structure of the human 17S U2 snRNPELECTRON MICROSCOPY2.5148
226Y53|1|2human 17S U2 snRNP low resolution partELECTRON MICROSCOPY7.198
235MQF|1|2+ 5MQF|1|6Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex)ELECTRON MICROSCOPY5.9140

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


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