#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. ÅDate
18H6L|1|5A (rep)U5 spliceosomal RNApre-mRNA, U5 snRNA, U6 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of human exon-defined spliceosome in the early B state.Electron microscopy2.62024-05-01
28H6K|1|5AU5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of human exon-defined spliceosome in the mature B state.Electron microscopy2.72024-05-01
38C6J|1|5U5 spliceosomal RNAPM5 5' Exon, U5 snRNAHomo sapiensEukaryaRF00020Human spliceosomal PM5 C* complexElectron microscopy2.82023-07-12
46QW6|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution.Electron microscopy2.922019-04-17
57DVQ|1|BU5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex)Electron microscopy2.892021-03-31
67QTT|1|eU5 spliceosomal RNAMINX, U5 snRNAHomo sapiensEukaryaRF00020Structural organization of a late activated human spliceosome (Baqr, core region)Electron microscopy3.12023-05-10
78QPE|1|5U5 spliceosomal RNAoligo1, oligo2, U5 snRNA, U6 snRNAHomo sapiensEukaryaRF00020Cryo-EM Structure of Pre-B-like Complex (core part)Electron microscopy3.12024-05-22
88Q7N|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)Electron microscopy3.12024-01-24
98H6E|1|5AU5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of human exon-defined spliceosome in the late pre-B state.Electron microscopy3.22024-05-01
108H6J|1|5AU5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state.Electron microscopy3.252024-05-01
118Q7Q|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 2)Electron microscopy3.22024-04-17
128Q91|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the human 20S U5 snRNP coreElectron microscopy3.12024-03-27
136QX9|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).Electron microscopy3.282019-04-17
148RC0|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the human 20S U5 snRNPElectron microscopy3.22024-03-27
158QOZ|1|5U5 spliceosomal RNA5'ss RNA oligo, U5 snRNA, U6 snRNAHomo sapiensEukaryaRF00020Cryo-EM Structure of Pre-B+5'ss+ATPgammaS Complex (core part)Electron microscopy3.12024-05-22
166QDV|1|5U5 spliceosomal RNALigated exons: MINX mRNA, U5 snRNAHomo sapiensEukaryaRF00020Human post-catalytic P complex spliceosomeElectron microscopy3.32019-02-20
176ZYM|1|5U5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Human C Complex Spliceosome - High-resolution COREElectron microscopy3.42020-10-14
188Y6O|1|BU5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP partElectron microscopy3.382024-03-20
196ICZ|1|BU5 spliceosomal RNApre-mRNA, U5snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstromElectron microscopy32019-03-13
208QP8|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Cryo-EM Structure of Pre-B Complex (core part)Electron microscopy3.52024-05-22
216FF4|1|5U5 spliceosomal RNApre mRNA, U2 snRNA, U5 snRNAHomo sapiensEukaryaRF00020human Bact spliceosome core structureElectron microscopy3.42018-08-29
226ID0|1|BU5 spliceosomal RNAU5snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolutionElectron microscopy2.92019-03-13
236ID1|1|BU5 spliceosomal RNAU5snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolutionElectron microscopy2.862019-03-13

Release history

Release3.3363.3373.3383.3393.3403.3413.342
Date2024-05-222024-05-292024-06-052024-06-122024-06-192024-06-262024-07-03

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Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.

#SViewPDBTitleMethodResolutionLength
17QTT|1|eStructural organization of a late activated human spliceosome (Baqr, core region)ELECTRON MICROSCOPY3.198
26FF4|1|5human Bact spliceosome core structureELECTRON MICROSCOPY3.470
36ZYM|1|5Human C Complex Spliceosome - High-resolution COREELECTRON MICROSCOPY3.474
48H6L|1|5ACryo-EM structure of human exon-defined spliceosome in the early B state.ELECTRON MICROSCOPY2.6115
58H6K|1|5ACryo-EM structure of human exon-defined spliceosome in the mature B state.ELECTRON MICROSCOPY2.7115
68QPE|1|5Cryo-EM Structure of Pre-B-like Complex (core part)ELECTRON MICROSCOPY3.1115
78QOZ|1|5Cryo-EM Structure of Pre-B+5'ss+ATPgammaS Complex (core part)ELECTRON MICROSCOPY3.179
88Q7N|1|5cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)ELECTRON MICROSCOPY3.1115
98H6E|1|5ACryo-EM structure of human exon-defined spliceosome in the late pre-B state.ELECTRON MICROSCOPY3.2114
108H6J|1|5ACryo-EM structure of human exon-defined spliceosome in the mature pre-B state.ELECTRON MICROSCOPY3.25114
118QP8|1|5Cryo-EM Structure of Pre-B Complex (core part)ELECTRON MICROSCOPY3.571
126QW6|1|5Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution.ELECTRON MICROSCOPY2.92104
136QX9|1|5Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).ELECTRON MICROSCOPY3.28104
148Q91|1|5Structure of the human 20S U5 snRNP coreELECTRON MICROSCOPY3.1104
158RC0|1|5Structure of the human 20S U5 snRNPELECTRON MICROSCOPY3.2104
168Q7Q|1|5Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 2)ELECTRON MICROSCOPY3.2104
178Y6O|1|BCryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP partELECTRON MICROSCOPY3.38109
188C6J|1|5Human spliceosomal PM5 C* complexELECTRON MICROSCOPY2.8113
196QDV|1|5Human post-catalytic P complex spliceosomeELECTRON MICROSCOPY3.375
207DVQ|1|BCryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex)ELECTRON MICROSCOPY2.8990
216ICZ|1|BCryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstromELECTRON MICROSCOPY397
226ID0|1|BCryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolutionELECTRON MICROSCOPY2.998
236ID1|1|BCryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolutionELECTRON MICROSCOPY2.8698

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


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