#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. ÅDate
15B2T|1|A (rep)Guide RNAStreptococcus pyogenesCrystal structure of the Streptococcus pyogenes Cas9 VRER variant in complex with sgRNA and target DNA (TGCG PAM)X-ray diffraction2.22016-03-23
25B2R|1|AGuide RNAStreptococcus pyogenesCrystal structure of the Streptococcus pyogenes Cas9 VQR variant in complex with sgRNA and target DNA (TGA PAM)X-ray diffraction22016-03-23
35B2S|1|AGuide RNAStreptococcus pyogenesCrystal structure of the Streptococcus pyogenes Cas9 EQR variant in complex with sgRNA and target DNA (TGAG PAM)X-ray diffraction2.22016-03-23
44OO8|1|BRNA (97-MER)Crystal structure of Streptococcus pyogenes Cas9 in complex with guide RNA and target DNAX-ray diffraction2.52014-02-26
54OO8|1|ERNA (97-MER)Crystal structure of Streptococcus pyogenes Cas9 in complex with guide RNA and target DNAX-ray diffraction2.52014-02-26
66AI6|1|BRNA (81-MER)Streptococcus pyogenesCrystal structure of SpCas9-NGX-ray diffraction2.72018-10-31
75XBL|1|BRNA (98-MER)Streptococcus pyogenesStructure of nuclease in complex with associated proteinX-ray diffraction3.052017-06-14
86IFO|1|CRNA (99-MER)Streptococcus pyogenesCrystal structure of AcrIIA2-SpyCas9-sgRNA ternary complexX-ray diffraction3.312019-01-23
96IFO|1|DRNA (99-MER)Streptococcus pyogenesCrystal structure of AcrIIA2-SpyCas9-sgRNA ternary complexX-ray diffraction3.312019-01-23
108SRS|1|BgRNAStreptococcus pyogenesSpRY-Cas9:gRNA complex targeting TAC PAM DNAElectron microscopy2.792024-05-01
118T7S|1|BgRNAStreptococcus pyogenesSpRYmer bound to NAC PAM DNAElectron microscopy3.012024-05-01
128T6X|1|BgRNAStreptococcus pyogenesSpRY-Cas9:gRNA complex targeting TAC PAM DNA with 18 bp R-loopElectron microscopy3.082024-05-01
138T6T|1|BgRNAStreptococcus pyogenesSpRY-Cas9:gRNA complex targeting TAC PAM DNA with 13 bp R-loopElectron microscopy3.042024-05-01
148SPQ|1|BgRNAStreptococcus pyogenesSpRY-Cas9:gRNA complex targeting TGG PAM DNAElectron microscopy3.262024-05-01
158T6Y|1|BgRNAStreptococcus pyogenesSpRY-Cas9:gRNA complex bound to non-target DNA with 1 bp R-loopElectron microscopy2.882024-05-01
168T78|1|BgRNAStreptococcus pyogenesSpRY-Cas9:gRNA complex bound to non-target DNA with 8 bp R-loopElectron microscopy3.022024-05-01
178T7S|1|HgRNAStreptococcus pyogenesSpRYmer bound to NAC PAM DNAElectron microscopy3.012024-05-01
188T6P|1|BgRNAStreptococcus pyogenesSpRY-Cas9:gRNA complex targeting TAC PAM DNA with 2 bp R-loopElectron microscopy3.152024-05-01
198T77|1|BgRNAStreptococcus pyogenesSpRY-Cas9:gRNA complex bound to non-target DNA with 6 bp R-loopElectron microscopy3.252024-05-01
208T6S|1|BgRNAStreptococcus pyogenesSpRY-Cas9:gRNA complex targeting TAC PAM DNA with 10 bp R-loopElectron microscopy3.282024-05-01
218SQH|1|BgRNAStreptococcus pyogenesSpRY-Cas9:gRNA complex targeting TTC PAM DNAElectron microscopy3.692024-05-01
228T76|1|BgRNAStreptococcus pyogenesSpRY-Cas9:gRNA complex targeting TAC PAM DNA with 3 bp R-loopElectron microscopy3.422024-05-01

Release history

Release3.333
Date2024-05-01

Parents

This classParent classesRelease idIntersectionAdded to this classOnly in parent

Children

This class Descendant classesRelease idIntersectionOnly in this classAdded to child

Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.

#SViewPDBTitleMethodResolutionLength
18T7S|1|HSpRYmer bound to NAC PAM DNAELECTRON MICROSCOPY3.0188
28T7S|1|BSpRYmer bound to NAC PAM DNAELECTRON MICROSCOPY3.0198
38T6X|1|BSpRY-Cas9:gRNA complex targeting TAC PAM DNA with 18 bp R-loopELECTRON MICROSCOPY3.0896
48SPQ|1|BSpRY-Cas9:gRNA complex targeting TGG PAM DNAELECTRON MICROSCOPY3.2698
58SRS|1|BSpRY-Cas9:gRNA complex targeting TAC PAM DNAELECTRON MICROSCOPY2.7998
68SQH|1|BSpRY-Cas9:gRNA complex targeting TTC PAM DNAELECTRON MICROSCOPY3.6998
78T6T|1|BSpRY-Cas9:gRNA complex targeting TAC PAM DNA with 13 bp R-loopELECTRON MICROSCOPY3.0495
88T76|1|BSpRY-Cas9:gRNA complex targeting TAC PAM DNA with 3 bp R-loopELECTRON MICROSCOPY3.4288
98T6P|1|BSpRY-Cas9:gRNA complex targeting TAC PAM DNA with 2 bp R-loopELECTRON MICROSCOPY3.1588
108T6S|1|BSpRY-Cas9:gRNA complex targeting TAC PAM DNA with 10 bp R-loopELECTRON MICROSCOPY3.2890
118T78|1|BSpRY-Cas9:gRNA complex bound to non-target DNA with 8 bp R-loopELECTRON MICROSCOPY3.0289
128T6Y|1|BSpRY-Cas9:gRNA complex bound to non-target DNA with 1 bp R-loopELECTRON MICROSCOPY2.8888
138T77|1|BSpRY-Cas9:gRNA complex bound to non-target DNA with 6 bp R-loopELECTRON MICROSCOPY3.2589
145XBL|1|BStructure of nuclease in complex with associated proteinX-RAY DIFFRACTION3.0588
156IFO|1|DCrystal structure of AcrIIA2-SpyCas9-sgRNA ternary complexX-RAY DIFFRACTION3.3190
166IFO|1|CCrystal structure of AcrIIA2-SpyCas9-sgRNA ternary complexX-RAY DIFFRACTION3.3188
174OO8|1|ECrystal structure of Streptococcus pyogenes Cas9 in complex with guide RNA and target DNAX-RAY DIFFRACTION2.597
185B2S|1|ACrystal structure of the Streptococcus pyogenes Cas9 EQR variant in complex with sgRNA and target DNA (TGAG PAM)X-RAY DIFFRACTION2.281
195B2R|1|ACrystal structure of the Streptococcus pyogenes Cas9 VQR variant in complex with sgRNA and target DNA (TGA PAM)X-RAY DIFFRACTION281
205B2T|1|ACrystal structure of the Streptococcus pyogenes Cas9 VRER variant in complex with sgRNA and target DNA (TGCG PAM)X-RAY DIFFRACTION2.281
216AI6|1|BCrystal structure of SpCas9-NGX-RAY DIFFRACTION2.781
224OO8|1|BCrystal structure of Streptococcus pyogenes Cas9 in complex with guide RNA and target DNAX-RAY DIFFRACTION2.597

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


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