#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. ÅDate
18H6L|1|5A (rep)U5 spliceosomal RNApre-mRNA, U5 snRNA, U6 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of human exon-defined spliceosome in the early B state.Electron microscopy2.62024-05-01
28H6K|1|5AU5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of human exon-defined spliceosome in the mature B state.Electron microscopy2.72024-05-01
38C6J|1|5U5 spliceosomal RNAPM5 5' Exon, U5 snRNAHomo sapiensEukaryaRF00020Human spliceosomal PM5 C* complexElectron microscopy2.82023-07-12
46QW6|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution.Electron microscopy2.922019-04-17
57DVQ|1|BU5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex)Electron microscopy2.892021-03-31
67QTT|1|eU5 spliceosomal RNAMINX, U5 snRNAHomo sapiensEukaryaRF00020Structural organization of a late activated human spliceosome (Baqr, core region)Electron microscopy3.12023-05-10
78QPE|1|5U5 spliceosomal RNAoligo1, oligo2, U5 snRNA, U6 snRNAHomo sapiensEukaryaRF00020Cryo-EM Structure of Pre-B-like Complex (core part)Electron microscopy3.12024-05-22
88Q7N|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)Electron microscopy3.12024-01-24
98H6E|1|5AU5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of human exon-defined spliceosome in the late pre-B state.Electron microscopy3.22024-05-01
108H6J|1|5AU5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state.Electron microscopy3.252024-05-01
118Q7Q|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 2)Electron microscopy3.22024-04-17
128Q91|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the human 20S U5 snRNP coreElectron microscopy3.12024-03-27
136QX9|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).Electron microscopy3.282019-04-17
148RC0|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the human 20S U5 snRNPElectron microscopy3.22024-03-27
158QOZ|1|5U5 spliceosomal RNA5'ss RNA oligo, U5 snRNA, U6 snRNAHomo sapiensEukaryaRF00020Cryo-EM Structure of Pre-B+5'ss+ATPgammaS Complex (core part)Electron microscopy3.12024-05-22
166QDV|1|5U5 spliceosomal RNALigated exons: MINX mRNA, U5 snRNAHomo sapiensEukaryaRF00020Human post-catalytic P complex spliceosomeElectron microscopy3.32019-02-20
176ZYM|1|5U5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Human C Complex Spliceosome - High-resolution COREElectron microscopy3.42020-10-14
188Y6O|1|BU5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP partElectron microscopy3.382024-03-20
196ICZ|1|BU5 spliceosomal RNApre-mRNA, U5snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstromElectron microscopy32019-03-13
207W59|1|BU5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020The cryo-EM structure of human pre-C*-I complexElectron microscopy3.62022-06-22
217W5A|1|BU5 spliceosomal RNAPre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020The cryo-EM structure of human pre-C*-II complexElectron microscopy3.62022-06-22
228QP8|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Cryo-EM Structure of Pre-B Complex (core part)Electron microscopy3.52024-05-22
236FF4|1|5U5 spliceosomal RNApre mRNA, U2 snRNA, U5 snRNAHomo sapiensEukaryaRF00020human Bact spliceosome core structureElectron microscopy3.42018-08-29
248Q7V|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 1)Electron microscopy3.82024-04-17
258QPA|1|5U5 spliceosomal RNA5'ss oligo, U5 snRNA, U6 snRNAHomo sapiensEukaryaRF00020Cryo-EM Structure of Pre-B+5'ssLNG Complex (core part)Electron microscopy3.72024-05-22
268QPB|1|5U5 spliceosomal RNA5'ss oligo, U5 snRNA, U6 snRNAHomo sapiensEukaryaRF00020Cryo-EM Structure of Pre-B+ATP Complex (core part)Electron microscopy3.72024-05-22
276ID0|1|BU5 spliceosomal RNAU5snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolutionElectron microscopy2.92019-03-13
285XJC|1|BU5 spliceosomal RNApre-mRNA, U5 snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstromElectron microscopy3.62017-07-05
298Q7W|1|5U5 spliceosomal RNAU5 snRNAHomo sapiensEukaryaRF00020Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 3)Electron microscopy3.92024-04-17
306ID1|1|BU5 spliceosomal RNAU5snRNAHomo sapiensEukaryaRF00020Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolutionElectron microscopy2.862019-03-13
316AHD|1|BU5 spliceosomal RNApre-mRNA, U5snRNAHomo sapiensEukaryaRF00020The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolutionElectron microscopy3.82018-11-14
327ABF|1|5U5 spliceosomal RNAMINX M3 RNA, U5 small nuclear RNAHomo sapiensEukaryaRF00020Human pre-Bact-1 spliceosome core structureElectron microscopy3.92020-12-09

Release history

Release3.3363.3373.3383.3393.3403.3413.342
Date2024-05-222024-05-292024-06-052024-06-122024-06-192024-06-262024-07-03

Parents

This classParent classesRelease idIntersectionAdded to this classOnly in parent

Children

This class Descendant classesRelease idIntersectionOnly in this classAdded to child

Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.

#SViewPDBTitleMethodResolutionLength
15XJC|1|BCryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstromELECTRON MICROSCOPY3.684
27QTT|1|eStructural organization of a late activated human spliceosome (Baqr, core region)ELECTRON MICROSCOPY3.198
38QPB|1|5Cryo-EM Structure of Pre-B+ATP Complex (core part)ELECTRON MICROSCOPY3.779
48QOZ|1|5Cryo-EM Structure of Pre-B+5'ss+ATPgammaS Complex (core part)ELECTRON MICROSCOPY3.179
58QPE|1|5Cryo-EM Structure of Pre-B-like Complex (core part)ELECTRON MICROSCOPY3.1115
68QPA|1|5Cryo-EM Structure of Pre-B+5'ssLNG Complex (core part)ELECTRON MICROSCOPY3.779
78Q7N|1|5cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)ELECTRON MICROSCOPY3.1115
86AHD|1|BThe Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolutionELECTRON MICROSCOPY3.8115
98H6K|1|5ACryo-EM structure of human exon-defined spliceosome in the mature B state.ELECTRON MICROSCOPY2.7115
108H6L|1|5ACryo-EM structure of human exon-defined spliceosome in the early B state.ELECTRON MICROSCOPY2.6115
117ABF|1|5Human pre-Bact-1 spliceosome core structureELECTRON MICROSCOPY3.958
126FF4|1|5human Bact spliceosome core structureELECTRON MICROSCOPY3.470
136ZYM|1|5Human C Complex Spliceosome - High-resolution COREELECTRON MICROSCOPY3.474
148H6E|1|5ACryo-EM structure of human exon-defined spliceosome in the late pre-B state.ELECTRON MICROSCOPY3.2114
158H6J|1|5ACryo-EM structure of human exon-defined spliceosome in the mature pre-B state.ELECTRON MICROSCOPY3.25114
168QP8|1|5Cryo-EM Structure of Pre-B Complex (core part)ELECTRON MICROSCOPY3.571
176QX9|1|5Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).ELECTRON MICROSCOPY3.28104
186QW6|1|5Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution.ELECTRON MICROSCOPY2.92104
198Q91|1|5Structure of the human 20S U5 snRNP coreELECTRON MICROSCOPY3.1104
208RC0|1|5Structure of the human 20S U5 snRNPELECTRON MICROSCOPY3.2104
218Q7W|1|5Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 3)ELECTRON MICROSCOPY3.9104
228Q7V|1|5Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 1)ELECTRON MICROSCOPY3.8104
238Q7Q|1|5Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 2)ELECTRON MICROSCOPY3.2104
248Y6O|1|BCryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP partELECTRON MICROSCOPY3.38109
257DVQ|1|BCryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex)ELECTRON MICROSCOPY2.8990
268C6J|1|5Human spliceosomal PM5 C* complexELECTRON MICROSCOPY2.8113
276QDV|1|5Human post-catalytic P complex spliceosomeELECTRON MICROSCOPY3.375
287W59|1|BThe cryo-EM structure of human pre-C*-I complexELECTRON MICROSCOPY3.684
297W5A|1|BThe cryo-EM structure of human pre-C*-II complexELECTRON MICROSCOPY3.684
306ID1|1|BCryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolutionELECTRON MICROSCOPY2.8698
316ID0|1|BCryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolutionELECTRON MICROSCOPY2.998
326ICZ|1|BCryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstromELECTRON MICROSCOPY397

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


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