#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. ÅDate
14ZT0|1|D (rep)single-guide RNAStreptococcus pyogenesCrystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolutionX-ray diffraction2.92015-07-08
24ZT0|1|Bsingle-guide RNAStreptococcus pyogenesCrystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolutionX-ray diffraction2.92015-07-08
34ZT9|1|Dsingle-guide RNAStreptococcus pyogenesNuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolutionX-ray diffraction3.12015-07-08
44ZT9|1|Bsingle-guide RNAStreptococcus pyogenesNuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolutionX-ray diffraction3.12015-07-08
57Z4D|1|AsgRNAsynthetic constructCrystal structure of SpCas9 bound to a 10 nucleotide complementary DNA substrateX-ray diffraction3.12022-08-31
67Z4D|1|FsgRNAsynthetic constructCrystal structure of SpCas9 bound to a 10 nucleotide complementary DNA substrateX-ray diffraction3.12022-08-31
77Z4L|1|AsgRNAsynthetic constructSpCas9 bound to 18-nucleotide complementary DNA substrate in the checkpoint stateElectron microscopy2.542022-08-31
87S4X|1|BgRNAsynthetic constructCas9:gRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformationElectron microscopy2.762022-03-02
97Z4J|1|AsgRNAsynthetic constructSpCas9 bound to 18-nucleotide complementary DNA substrate in the catalytic stateElectron microscopy2.992022-08-31
106O0X|1|Bsingle guide RNAsynthetic constructConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumElectron microscopy3.282019-07-10
117Z4I|1|AsgRNAsynthetic constructSpCas9 bound to 16-nucleotide complementary DNA substrateElectron microscopy3.122022-08-31
127S4V|1|BgRNAsynthetic constructCas9 bound to 12-14MM DNA, 60 min time-point, kinked conformationElectron microscopy3.282022-03-02
136O0Y|1|Bsingle guide RNAsynthetic constructConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumElectron microscopy3.372019-07-10
146O0Z|1|Bsingle guide RNAsynthetic constructConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumElectron microscopy3.32019-07-10
157Z4H|1|AsgRNAsynthetic constructSpCas9 bound to 14-nucleotide complementary DNA substrateElectron microscopy3.492022-08-31

Release history

Release3.2463.2473.2483.2493.2503.2513.2523.2533.2543.2553.2563.2573.2583.2593.2603.2613.2623.2633.2643.2653.2663.2673.2683.2693.2703.2713.2723.2733.2743.2753.2763.2773.2783.2793.2803.2813.2823.2833.2843.2853.2863.2873.2883.2893.2903.2913.2923.2933.2943.2953.2963.2973.2983.2993.3003.3013.3023.3033.3043.3053.3063.3073.3083.3093.3103.3113.3123.3133.3143.3153.3163.3173.3183.3193.3203.3213.3223.3233.3243.3253.3263.3273.3283.3293.3303.3313.332
Date2022-08-312022-09-072022-09-142022-09-212022-09-282022-10-052022-10-122022-10-192022-10-262022-11-022022-11-092022-11-162022-11-232022-11-302022-12-072022-12-142022-12-212022-12-282023-01-042023-01-112023-01-182023-01-252023-02-012023-02-082023-02-152023-02-222023-03-012023-03-082023-03-152023-03-222023-03-292023-04-052023-04-122023-04-192023-04-262023-05-032023-05-102023-05-172023-05-242023-05-312023-06-072023-06-142023-06-212023-06-282023-07-052023-07-122023-07-192023-07-262023-08-022023-08-092023-08-162023-08-232023-08-302023-09-062023-09-132023-09-202023-09-272023-10-042023-10-112023-10-182023-10-252023-11-012023-11-082023-11-152023-11-242023-11-292023-12-062023-12-132023-12-202023-12-272024-01-032024-01-102024-01-172024-01-242024-01-312024-02-072024-02-142024-02-212024-02-282024-03-062024-03-132024-03-202024-03-272024-04-032024-04-102024-04-172024-04-24

Parents

This classParent classesRelease idIntersectionAdded to this classOnly in parent
NR_3.5_20965.1NR_3.5_30925.23.246(9) 4ZT9|1|D, 7S4X|1|B, 4ZT9|1|B, 7S4V|1|B, 4ZT0|1|D, 6O0Z|1|B, 4ZT0|1|B, 6O0Y|1|B, 6O0X|1|B(6) 7Z4H|1|A, 7Z4J|1|A, 7Z4D|1|F, 7Z4I|1|A, 7Z4D|1|A, 7Z4L|1|A(0)

Children

This class Descendant classesRelease idIntersectionOnly in this classAdded to child

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. Instances are ordered to put similar structures near each other. The colorbar ranges from 0 to the maximum observed discrepancy, up to 0.5

#S - ordering by similarity (same as in the heat map).
#SPDBTitleMethodResolutionLength
17S4V|1|BCas9 bound to 12-14MM DNA, 60 min time-point, kinked conformationELECTRON MICROSCOPY3.2898
26O0Y|1|BConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.3798
36O0X|1|BConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.2898
46O0Z|1|BConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.396
57Z4H|1|ASpCas9 bound to 14-nucleotide complementary DNA substrateELECTRON MICROSCOPY3.4992
67Z4I|1|ASpCas9 bound to 16-nucleotide complementary DNA substrateELECTRON MICROSCOPY3.1296
77Z4L|1|ASpCas9 bound to 18-nucleotide complementary DNA substrate in the checkpoint stateELECTRON MICROSCOPY2.5496
87Z4J|1|ASpCas9 bound to 18-nucleotide complementary DNA substrate in the catalytic stateELECTRON MICROSCOPY2.9998
97S4X|1|BCas9:gRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformationELECTRON MICROSCOPY2.7698
107Z4D|1|ACrystal structure of SpCas9 bound to a 10 nucleotide complementary DNA substrateX-RAY DIFFRACTION3.175
117Z4D|1|FCrystal structure of SpCas9 bound to a 10 nucleotide complementary DNA substrateX-RAY DIFFRACTION3.177
124ZT9|1|BNuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolutionX-RAY DIFFRACTION3.172
134ZT0|1|BCrystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolutionX-RAY DIFFRACTION2.972
144ZT0|1|DCrystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolutionX-RAY DIFFRACTION2.972
154ZT9|1|DNuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolutionX-RAY DIFFRACTION3.172
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