1 | 8GLP|1|L5+ 8GLP|1|L8 (rep) | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure) | Electron microscopy | 1.67 | 2023-04-19 |
2 | 8QOI|1|L5+ 8QOI|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA (3773-MER), 5.8S rRNA (156-MER) | Homo sapiens | Eukarya | RF02543 + RF00002 | Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA | Electron microscopy | 1.9 | 2024-06-12 |
3 | 8YOO|1|L5+ 8YOO|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline | Electron microscopy | 2 | 2024-07-10 |
4 | 8A3D|1|A+ 8A3D|1|C | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S ribosomal RNA, 5.8S ribosomal RNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human mature large subunit of the ribosome with eIF6 and homoharringtonine bound | Electron microscopy | 1.67 | 2023-03-08 |
5 | 8YOP|1|L5+ 8YOP|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Cryo-EM structure of the human 80S ribosome with 4 um Tigecycline | Electron microscopy | 2.2 | 2024-07-10 |
6 | 8XSX|1|L5+ 8XSX|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 | Electron microscopy | 2.4 | 2024-07-10 |
7 | 8K2C|1|L5+ 8K2C|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Cryo-EM structure of the human 80S ribosome with Tigecycline | Electron microscopy | 2.4 | 2024-07-10 |
8 | 8G5Y|1|L5+ 8G5Y|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) | Electron microscopy | 2.29 | 2023-04-19 |
9 | 8JDK|1|D | Large subunit ribosomal RNA | 28S ribosomal RNA | Homo sapiens | Eukarya | RF02543 | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU) | Electron microscopy | 2.26 | 2023-12-06 |
10 | 7XNY|1|L1+ 7XNY|1|L3 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells | Electron microscopy | 2.5 | 2023-04-05 |
11 | 6ZMI|1|L5+ 6ZMI|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S ribosomal RNA, 5.8S ribosomal RNA | Homo sapiens | Eukarya | RF02543 + RF00002 | SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex | Electron microscopy | 2.6 | 2020-08-19 |
12 | 8IFE|1|1A+ 8IFE|1|1C | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S ribosomal RNA, 5.8S ribosomal RNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Arbekacin-added human 80S ribosome | Electron microscopy | 2.57 | 2024-02-14 |
13 | 8IFD|1|1A+ 8IFD|1|1C | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S ribosomal RNA, 5.8S ribosomal RNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Dibekacin-added human 80S ribosome | Electron microscopy | 2.59 | 2024-02-14 |
14 | 7OW7|1|A+ 7OW7|1|C | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S ribosomal RNA | Homo sapiens | Eukarya | RF02543 + RF00002 | EIF6-bound large subunit of the human ribosome | Electron microscopy | 2.2 | 2022-10-05 |
15 | 8QFD|1|5+ 8QFD|1|8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | UFL1 E3 ligase bound 60S ribosome | Electron microscopy | 2.2 | 2024-02-21 |
16 | 8JDL|1|D | Large subunit ribosomal RNA | 28S ribosomal RNA | Homo sapiens | Eukarya | RF02543 | Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state) | Electron microscopy | 2.42 | 2023-12-06 |
17 | 6ZM7|1|L5+ 6ZM7|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S ribosomal RNA, 5.8S ribosomal RNA | Homo sapiens | Eukarya | RF02543 + RF00002 | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex | Electron microscopy | 2.7 | 2020-07-29 |
18 | 8G60|1|L5+ 8G60|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) | Electron microscopy | 2.54 | 2023-04-19 |
19 | 7XNX|1|L1+ 7XNX|1|L3 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells | Electron microscopy | 2.7 | 2023-04-05 |
20 | 8JDJ|1|D | Large subunit ribosomal RNA | 28S ribosomal RNA | Homo sapiens | Eukarya | RF02543 | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU) | Electron microscopy | 2.5 | 2023-12-06 |
21 | 8G5Z|1|L5+ 8G5Z|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) | Electron microscopy | 2.64 | 2023-04-19 |
22 | 7F5S|1|L5+ 7F5S|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | human delta-METTL18 60S ribosome | Electron microscopy | 2.72 | 2022-06-22 |
23 | 8FL3|1|L3+ 8FL3|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nuclear pre-60S ribosomal subunit (State I2) | Electron microscopy | 2.53 | 2023-07-12 |
24 | 6Y6X|1|L5+ 6Y6X|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S ribosomal RNA, 5.8S ribosomal RNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Tetracenomycin X bound to the human ribosome | Electron microscopy | 2.8 | 2020-07-08 |
25 | 6Z6N|1|L5+ 6Z6N|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1) | Electron microscopy | 2.9 | 2020-07-29 |
26 | 8FLE|1|L3+ 8FLE|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nuclear pre-60S ribosomal subunit (State L2) | Electron microscopy | 2.48 | 2023-07-12 |
27 | 8FLB|1|L3+ 8FLB|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nuclear pre-60S ribosomal subunit (State K2) | Electron microscopy | 2.55 | 2023-07-12 |
28 | 8JDM|1|D | Large subunit ribosomal RNA | 28S ribosomal RNA | Homo sapiens | Eukarya | RF02543 | Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (rotated state) | Electron microscopy | 2.67 | 2023-12-06 |
29 | 8FL7|1|L3+ 8FL7|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nuclear pre-60S ribosomal subunit (State J2) | Electron microscopy | 2.55 | 2023-07-12 |
30 | 8G6J|1|L5+ 8G6J|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2) | Electron microscopy | 2.8 | 2023-04-19 |
31 | 9GMO|1|A | Large subunit ribosomal RNA | 28S rRNA | Homo sapiens | Eukarya | RF02543 | eIF6-bound pre-60S large ribosomal subunit incorporating mutant uL16 | Electron microscopy | 2.59 | 2024-10-02 |
32 | 6QZP|1|L5+ 6QZP|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA (3773-MER), 5.8S rRNA (156-MER) | Homo sapiens | Eukarya | RF02543 + RF00002 | High-resolution cryo-EM structure of the human 80S ribosome | Electron microscopy | 2.9 | 2019-04-24 |
33 | 6ZME|1|L5+ 6ZME|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S ribosomal RNA, 5.8S ribosomal RNA | Homo sapiens | Eukarya | RF02543 + RF00002 | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex | Electron microscopy | 3 | 2020-08-12 |
34 | 6Z6L|1|L5+ 6Z6L|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Cryo-EM structure of human CCDC124 bound to 80S ribosomes | Electron microscopy | 3 | 2020-07-29 |
35 | 8XSY|1|L5+ 8XSY|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head Swivelled) | Electron microscopy | 3 | 2024-07-10 |
36 | 7QVP|1|L5+ 7QVP|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S ribosomal RNA, 5.8S ribosomal RNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human collided disome (di-ribosome) stalled on XBP1 mRNA | Electron microscopy | 3 | 2022-10-12 |
37 | 8FLD|1|L3+ 8FLD|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nuclear pre-60S ribosomal subunit (State L1) | Electron microscopy | 2.58 | 2023-07-12 |
38 | 8FL6|1|L3+ 8FL6|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nuclear pre-60S ribosomal subunit (State J1) | Electron microscopy | 2.62 | 2023-07-12 |
39 | 8FLA|1|L3+ 8FLA|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nuclear pre-60S ribosomal subunit (State K1) | Electron microscopy | 2.63 | 2023-07-12 |
40 | 8FL2|1|L3+ 8FL2|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nuclear pre-60S ribosomal subunit (State I1) | Electron microscopy | 2.67 | 2023-07-12 |
41 | 7QVP|1|L6+ 7QVP|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S ribosomal RNA, 5.8S ribosomal RNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human collided disome (di-ribosome) stalled on XBP1 mRNA | Electron microscopy | 3 | 2022-10-12 |
42 | 8IDT|1|2+ 8IDT|1|8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | human nuclear pre-60S ribosomal particle - State G | Electron microscopy | 2.8 | 2023-08-09 |
43 | 6XA1|1|L5+ 6XA1|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Structure of a drug-like compound stalled human translation termination complex | Electron microscopy | 2.8 | 2020-10-07 |
44 | 8FLF|1|L3+ 8FLF|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nuclear pre-60S ribosomal subunit (State L3) | Electron microscopy | 2.65 | 2023-07-12 |
45 | 8G61|1|L5+ 8G61|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) | Electron microscopy | 2.94 | 2023-04-19 |
46 | 8OJ5|1|5+ 8OJ5|1|8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (in-vitro reconstitution) | Electron microscopy | 2.9 | 2024-02-21 |
47 | 8INF|1|2+ 8INF|1|8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | human nuclear pre-60S ribosomal particle - State F' | Electron microscopy | 3 | 2023-08-09 |
48 | 8IDY|1|2+ 8IDY|1|8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | human nuclear pre-60S ribosomal particle - State F | Electron microscopy | 3 | 2023-08-09 |
49 | 8FL9|1|L3+ 8FL9|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nuclear pre-60S ribosomal subunit (State J3) | Electron microscopy | 2.75 | 2023-07-12 |
50 | 8FLC|1|L3+ 8FLC|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nuclear pre-60S ribosomal subunit (State K3) | Electron microscopy | 2.76 | 2023-07-12 |
51 | 6Y2L|1|L5+ 6Y2L|1|L8 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S ribosomal RNA, 5.8S ribosomal RNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Structure of human ribosome in POST state | Electron microscopy | 3 | 2020-04-15 |
52 | 8FL4|1|L3+ 8FL4|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nuclear pre-60S ribosomal subunit (State I3) | Electron microscopy | 2.89 | 2023-07-12 |
53 | 8FKY|1|L3+ 8FKY|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nucleolar pre-60S ribosomal subunit (State F) | Electron microscopy | 2.67 | 2023-07-12 |
54 | 8FKW|1|L3+ 8FKW|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nucleolar pre-60S ribosomal subunit (State D2) | Electron microscopy | 2.5 | 2023-07-12 |
55 | 8FKV|1|L3+ 8FKV|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nucleolar pre-60S ribosomal subunit (State D1) | Electron microscopy | 2.47 | 2023-07-12 |
56 | 8FKX|1|L3+ 8FKX|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nucleolar pre-60S ribosomal subunit (State E) | Electron microscopy | 2.59 | 2023-07-12 |
57 | 8FKU|1|L3+ 8FKU|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nucleolar pre-60S ribosomal subunit (State C2) | Electron microscopy | 2.82 | 2023-07-12 |
58 | 8FKT|1|L3+ 8FKT|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nucleolar pre-60S ribosomal subunit (State C1) | Electron microscopy | 2.81 | 2023-07-12 |
59 | 8FKS|1|L3+ 8FKS|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nucleolar pre-60S ribosomal subunit (State B2) | Electron microscopy | 2.88 | 2023-07-12 |
60 | 8FKR|1|L3+ 8FKR|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nucleolar pre-60S ribosomal subunit (State B1) | Electron microscopy | 2.89 | 2023-07-12 |
61 | 8FKQ|1|L3+ 8FKQ|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nucleolar pre-60S ribosomal subunit (State A2) | Electron microscopy | 2.76 | 2023-07-12 |
62 | 8FKP|1|L3+ 8FKP|1|L1 | Large subunit ribosomal RNA + 5.8S ribosomal RNA | 28S rRNA, 5.8S rRNA | Homo sapiens | Eukarya | RF02543 + RF00002 | Human nucleolar pre-60S ribosomal subunit (State A1) | Electron microscopy | 2.85 | 2023-07-12 |
63 | 8FL0|1|L3 | Large subunit ribosomal RNA | 28S rRNA | Homo sapiens | Eukarya | RF02543 | Human nucleolar pre-60S ribosomal subunit (State H) | Electron microscopy | 2.91 | 2023-07-12 |
64 | 8ONY|1|5 | Large subunit ribosomal RNA | 28S rRNA | Homo sapiens | Eukarya | RF02543 | Human Methionine Aminopeptidase 2 at the 80S ribosome | Electron microscopy | 2.92 | 2024-02-21 |