Equivalence class NR_20.0_65061.11 Obsolete
| # | IFE | Compound(s) | RNA source organism | Title | Method | Resolution | Date |
|---|---|---|---|---|---|---|---|
| 1 | 6ZMI|1|L5+ 6ZMI|1|L8 (rep) | 28S ribosomal RNA, 5.8S ribosomal RNA | SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex | ELECTRON MICROSCOPY | 2.6 | 2020-08-19 | |
| 2 | 6ZM7|1|L5+ 6ZM7|1|L8 | 28S ribosomal RNA, 5.8S ribosomal RNA | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex | ELECTRON MICROSCOPY | 2.7 | 2020-07-29 | |
| 3 | 6Y6X|1|L5+ 6Y6X|1|L8 | 28S ribosomal RNA, 5.8S ribosomal RNA | Tetracenomycin X bound to the human ribosome | ELECTRON MICROSCOPY | 2.8 | 2020-07-08 | |
| 4 | 6Z6N|1|L5+ 6Z6N|1|L8 | 28S rRNA, 5.8S rRNA | Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1) | ELECTRON MICROSCOPY | 2.9 | 2020-07-29 | |
| 5 | 6QZP|1|L5+ 6QZP|1|L8 | 28S rRNA (3773-MER), 5.8S rRNA (156-MER) | High-resolution cryo-EM structure of the human 80S ribosome | ELECTRON MICROSCOPY | 2.9 | 2019-04-24 | |
| 6 | 6ZME|1|L5+ 6ZME|1|L8 | 28S ribosomal RNA, 5.8S ribosomal RNA | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex | ELECTRON MICROSCOPY | 3 | 2020-08-12 | |
| 7 | 6Z6L|1|L5+ 6Z6L|1|L8 | 28S rRNA, 5.8S rRNA | Cryo-EM structure of human CCDC124 bound to 80S ribosomes | ELECTRON MICROSCOPY | 3 | 2020-07-29 | |
| 8 | 6EK0|1|L5+ 6EK0|1|L8 | 28S ribosomal RNA, 5.8S ribosomal RNA | High-resolution cryo-EM structure of the human 80S ribosome | ELECTRON MICROSCOPY | 2.9 | 2018-01-24 | |
| 9 | 6XA1|1|L5+ 6XA1|1|L8 | 28S rRNA, 5.8S rRNA | Structure of a drug-like compound stalled human translation termination complex | ELECTRON MICROSCOPY | 2.8 | 2020-10-07 | |
| 10 | 6ZMO|1|L5+ 6ZMO|1|L8 | 28S ribosomal RNA, 5.8S ribosomal RNA | SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex | ELECTRON MICROSCOPY | 3.1 | 2020-08-19 | |
| 11 | 6Z6M|1|L5+ 6Z6M|1|L8 | 28S rRNA, 5.8S rRNA | Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1 | ELECTRON MICROSCOPY | 3.1 | 2020-07-29 | |
| 12 | 6OLE|1|t+ 6OLE|1|D | 28S ribosomal RNA, 5.8S ribosomal RNA | Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs | ELECTRON MICROSCOPY | 3.1 | 2019-06-19 | |
| 13 | 6OM0|1|t+ 6OM0|1|D | 28S ribosomal RNA, 5.8S ribosomal RNA | Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs | ELECTRON MICROSCOPY | 3.1 | 2019-06-19 | |
| 14 | 6Y2L|1|L5+ 6Y2L|1|L8 | 28S ribosomal RNA, 5.8S ribosomal RNA | Structure of human ribosome in POST state | ELECTRON MICROSCOPY | 3 | 2020-04-15 | |
| 15 | 6LQM|1|2+ 6LQM|1|8 | 28S rRNA, 5.8S rRNA | Cryo-EM structure of a pre-60S ribosomal subunit - state C | ELECTRON MICROSCOPY | 3.09 | 2020-08-26 | |
| 16 | 6Y0G|1|L5+ 6Y0G|1|L8 | 28S ribosomal RNA, 5.8S ribosomal RNA | Structure of human ribosome in classical-PRE state | ELECTRON MICROSCOPY | 3.2 | 2020-04-15 | |
| 17 | 7BHP|1|L5+ 7BHP|1|L8 | 28S ribosomal RNA, 5.8S ribosomal RNA | Cryo-EM structure of the human Ebp1 - 80S ribosome | ELECTRON MICROSCOPY | 3.3 | 2021-02-03 | |
| 18 | 6LU8|1|2+ 6LU8|1|8 | 28S rRNA, 5.8S rRNA | Cryo-EM structure of a human pre-60S ribosomal subunit - state A | ELECTRON MICROSCOPY | 3.13 | 2020-08-26 | |
| 19 | 6LSR|1|2+ 6LSR|1|8 | 28S rRNA, 5.8S rRNA | Cryo-EM structure of a pre-60S ribosomal subunit - state B | ELECTRON MICROSCOPY | 3.13 | 2020-08-26 | |
| 20 | 6LSS|1|2+ 6LSS|1|8 | 28S rRNA | Cryo-EM structure of a pre-60S ribosomal subunit - state preA | ELECTRON MICROSCOPY | 3.23 | 2020-08-26 | |
| 21 | 6OLI|1|t+ 6OLI|1|D | 28S ribosomal RNA, 5.8S ribosomal RNA | Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC) | ELECTRON MICROSCOPY | 3.5 | 2019-06-19 | |
| 22 | 6OLG|1|A2+ 6OLG|1|A3 | 28S ribosomal RNA, 5.8S ribosomal RNA | Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA) | ELECTRON MICROSCOPY | 3.4 | 2019-06-19 | |
| 23 | 6Y57|1|L5+ 6Y57|1|L8 | 28S ribosomal RNA, 5.8S ribosomal RNA | Structure of human ribosome in hybrid-PRE state | ELECTRON MICROSCOPY | 3.5 | 2020-04-15 | |
| 24 | 5T2C|1|A+ 5T2C|1|C | 28S rRNA, 5.8S rRNA | CryoEM structure of the human ribosome at 3.6 Angstrom resolution | ELECTRON MICROSCOPY | 3.6 | 2017-01-25 | |
| 25 | 6OM7|1|t+ 6OM7|1|D | 28S ribosomal RNA, 5.8S ribosomal RNA | Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs | ELECTRON MICROSCOPY | 3.7 | 2019-06-19 | |
| 26 | 4UG0|1|L5+ 4UG0|1|L8 | 28S ribosomal RNA, 5.8S ribosomal RNA | STRUCTURE OF THE HUMAN 80S RIBOSOME | ELECTRON MICROSCOPY | 3.6 | 2015-06-10 | |
| 27 | 6OLF|1|t+ 6OLF|1|D | 28S ribosomal RNA, 5.8S ribosomal RNA | Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs | ELECTRON MICROSCOPY | 3.9 | 2019-06-19 | |
| 28 | 6W6L|1|t+ 6W6L|1|D | 28S ribosomal RNA, 5.8S ribosomal RNA | Cryo-EM structure of the human ribosome-TMCO1 translocon | ELECTRON MICROSCOPY | 3.84 | 2020-09-02 | |
| 29 | 6IP5|1|1A+ 6IP5|1|1C | 28S ribosomal RNA, 5.8S ribosomal RNA | Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii) | ELECTRON MICROSCOPY | 3.9 | 2019-05-29 | |
| 30 | 6IP8|1|1A+ 6IP8|1|1C | 28S ribosomal RNA, 5.8S ribosomal RNA | Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv) | ELECTRON MICROSCOPY | 3.9 | 2019-05-29 | |
| 31 | 6OLZ|1|A2+ 6OLZ|1|A3 | 28S ribosomal RNA, 5.8S ribosomal RNA | Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA | ELECTRON MICROSCOPY | 3.9 | 2019-06-19 | |
| 32 | 5AJ0|1|A2+ 5AJ0|1|A3 | 28S ribosomal RNA, 5.8S ribosomal RNA | Cryo electron microscopy of actively translating human polysomes (POST state). | ELECTRON MICROSCOPY | 3.5 | 2015-05-20 | |
| 33 | 5LKS|1|L5+ 5LKS|1|L8 | 28S ribosomal RNA, 5.8S ribosomal RNA | Structure-function insights reveal the human ribosome as a cancer target for antibiotics | ELECTRON MICROSCOPY | 3.6 | 2017-04-26 | |
| 34 | 6IP6|1|1A+ 6IP6|1|1C | 28S ribosomal RNA, 5.8S ribosomal RNA | Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii) | ELECTRON MICROSCOPY | 4.5 | 2019-05-29 | |
| 35 | 4V6X|1|A5+ 4V6X|1|A8 | 28S ribosomal RNA, 5.8S ribosomal RNA | Structure of the human 80S ribosome | ELECTRON MICROSCOPY | 5 | 2014-07-09 | |
| 36 | 6SXO|1|L5 | 28S ribosomal RNA including ES27L-B (2839-3265) | Homo sapiens | Cryo-EM structure of the human Ebp1-ribosome complex | ELECTRON MICROSCOPY | 3.3 | 2020-02-19 |
| 37 | 5A8L|1|A | 28S RIBOSOMAL RNA | Homo sapiens | Human eRF1 and the hCMV nascent peptide in the translation termination complex | ELECTRON MICROSCOPY | 3.8 | 2015-12-02 |
Release history
| Release | 3.164 | 3.165 | 3.166 | 3.167 | 3.168 | 3.169 | 3.170 | 3.171 | 3.172 | 3.173 | 3.174 | 3.175 | 3.176 | 3.177 | 3.178 | 3.179 | 3.180 | 3.181 | 3.182 | 3.183 | 3.184 | 3.185 | 3.186 | 3.187 | 3.188 | 3.189 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Date | 2021-02-03 | 2021-02-10 | 2021-02-17 | 2021-02-24 | 2021-03-03 | 2021-03-10 | 2021-03-17 | 2021-03-24 | 2021-03-31 | 2021-04-07 | 2021-04-14 | 2021-04-21 | 2021-04-28 | 2021-05-05 | 2021-05-12 | 2021-05-19 | 2021-05-26 | 2021-06-02 | 2021-06-09 | 2021-06-16 | 2021-06-23 | 2021-06-30 | 2021-07-07 | 2021-07-14 | 2021-07-21 | 2021-07-28 |
Parents
| This class | Parent classes | Release id | Intersection | Added to this class | Only in parent |
|---|---|---|---|---|---|
| NR_20.0_65061.11 | NR_20.0_65061.10 | 3.164 | (36) 6ZM7|1|L5+6ZM7|1|L8, 4UG0|1|L5+4UG0|1|L8, 6Z6N|1|L5+6Z6N|1|L8, 6Z6M|1|L5+6Z6M|1|L8, 6Z6L|1|L5+6Z6L|1|L8, 6Y6X|1|L5+6Y6X|1|L8, 6Y57|1|L5+6Y57|1|L8, 6Y2L|1|L5+6Y2L|1|L8, 6Y0G|1|L5+6Y0G|1|L8, 6XA1|1|L5+6XA1|1|L8, 6W6L|1|t+6W6L|1|D, 6SXO|1|L5, 6QZP|1|L5+6QZP|1|L8, 6OM7|1|t+6OM7|1|D, 6OM0|1|t+6OM0|1|D, 6OLZ|1|A2+6OLZ|1|A3, 6OLI|1|t+6OLI|1|D, 6OLG|1|A2+6OLG|1|A3, 6OLF|1|t+6OLF|1|D, 6OLE|1|t+6OLE|1|D, 6LU8|1|2+6LU8|1|8, 6LSS|1|2+6LSS|1|8, 6LSR|1|2+6LSR|1|8, 6LQM|1|2+6LQM|1|8, 6IP8|1|1A+6IP8|1|1C, 6IP6|1|1A+6IP6|1|1C, 6IP5|1|1A+6IP5|1|1C, 6EK0|1|L5+6EK0|1|L8, 5T2C|1|A+5T2C|1|C, 5LKS|1|L5+5LKS|1|L8, 6ZMO|1|L5+6ZMO|1|L8, 5AJ0|1|A2+5AJ0|1|A3, 6ZMI|1|L5+6ZMI|1|L8, 5A8L|1|A, 6ZME|1|L5+6ZME|1|L8, 4V6X|1|A5+4V6X|1|A8 | (1) 7BHP|1|L5+7BHP|1|L8 | (0) |
Children
| This class | Descendant classes | Release id | Intersection | Only in this class | Added to child |
|---|---|---|---|---|---|
| NR_20.0_65061.11 | NR_20.0_65061.12 | 3.190 | (36) 6Y6X|1|L5+6Y6X|1|L8, 6LSS|1|2+6LSS|1|8, 6QZP|1|L5+6QZP|1|L8, 5LKS|1|L5+5LKS|1|L8, 6Z6M|1|L5+6Z6M|1|L8, 6OLE|1|t+6OLE|1|D, 6W6L|1|t+6W6L|1|D, 6IP5|1|1A+6IP5|1|1C, 6ZM7|1|L5+6ZM7|1|L8, 6OLG|1|A2+6OLG|1|A3, 6Y0G|1|L5+6Y0G|1|L8, 6IP8|1|1A+6IP8|1|1C, 6ZMI|1|L5+6ZMI|1|L8, 4V6X|1|A5+4V6X|1|A8, 6OLZ|1|A2+6OLZ|1|A3, 6Y57|1|L5+6Y57|1|L8, 6LSR|1|2+6LSR|1|8, 7BHP|1|L5+7BHP|1|L8, 5AJ0|1|A2+5AJ0|1|A3, 6OM7|1|t+6OM7|1|D, 6Z6L|1|L5+6Z6L|1|L8, 6LU8|1|2+6LU8|1|8, 6SXO|1|L5, 5T2C|1|A+5T2C|1|C, 6Z6N|1|L5+6Z6N|1|L8, 6OLF|1|t+6OLF|1|D, 6XA1|1|L5+6XA1|1|L8, 6IP6|1|1A+6IP6|1|1C, 6ZME|1|L5+6ZME|1|L8, 4UG0|1|L5+4UG0|1|L8, 6OLI|1|t+6OLI|1|D, 6Y2L|1|L5+6Y2L|1|L8, 6LQM|1|2+6LQM|1|8, 6ZMO|1|L5+6ZMO|1|L8, 5A8L|1|A, 6OM0|1|t+6OM0|1|D | (1) 6EK0|1|L5+6EK0|1|L8 | (0) |
Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. Instances are ordered to put similar structures near each other. The colorbar ranges from 0 to the maximum observed discrepancy, up to 0.5
#S - ordering by similarity (same as in the heat map).| #S | PDB | Title | Method | Resolution | Length |
|---|---|---|---|---|---|
| 1 | 5A8L|1|A | Human eRF1 and the hCMV nascent peptide in the translation termination complex | ELECTRON MICROSCOPY | 3.8 | 253 |
| 2 | 6LQM|1|2+6LQM|1|8 | Cryo-EM structure of a pre-60S ribosomal subunit - state C | ELECTRON MICROSCOPY | 3.09 | 3433 |
| 3 | 6ZME|1|L5+6ZME|1|L8 | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex | ELECTRON MICROSCOPY | 3 | 3773 |
| 4 | 6ZMO|1|L5+6ZMO|1|L8 | SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex | ELECTRON MICROSCOPY | 3.1 | 3773 |
| 5 | 6ZMI|1|L5+6ZMI|1|L8 | SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex | ELECTRON MICROSCOPY | 2.6 | 3773 |
| 6 | 6Z6M|1|L5+6Z6M|1|L8 | Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1 | ELECTRON MICROSCOPY | 3.1 | 3772 |
| 7 | 6ZM7|1|L5+6ZM7|1|L8 | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex | ELECTRON MICROSCOPY | 2.7 | 3773 |
| 8 | 6Z6L|1|L5+6Z6L|1|L8 | Cryo-EM structure of human CCDC124 bound to 80S ribosomes | ELECTRON MICROSCOPY | 3 | 3772 |
| 9 | 6Z6N|1|L5+6Z6N|1|L8 | Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1) | ELECTRON MICROSCOPY | 2.9 | 3772 |
| 10 | 6Y6X|1|L5+6Y6X|1|L8 | Tetracenomycin X bound to the human ribosome | ELECTRON MICROSCOPY | 2.8 | 3773 |
| 11 | 6EK0|1|L5+6EK0|1|L8 | High-resolution cryo-EM structure of the human 80S ribosome | ELECTRON MICROSCOPY | 2.9 | 3672 |
| 12 | 6QZP|1|L5+6QZP|1|L8 | High-resolution cryo-EM structure of the human 80S ribosome | ELECTRON MICROSCOPY | 2.9 | 3696 |
| 13 | 6Y57|1|L5+6Y57|1|L8 | Structure of human ribosome in hybrid-PRE state | ELECTRON MICROSCOPY | 3.5 | 3574 |
| 14 | 6Y0G|1|L5+6Y0G|1|L8 | Structure of human ribosome in classical-PRE state | ELECTRON MICROSCOPY | 3.2 | 3644 |
| 15 | 6Y2L|1|L5+6Y2L|1|L8 | Structure of human ribosome in POST state | ELECTRON MICROSCOPY | 3 | 3613 |
| 16 | 7BHP|1|L5+7BHP|1|L8 | Cryo-EM structure of the human Ebp1 - 80S ribosome | ELECTRON MICROSCOPY | 3.3 | 3644 |
| 17 | 6XA1|1|L5+6XA1|1|L8 | Structure of a drug-like compound stalled human translation termination complex | ELECTRON MICROSCOPY | 2.8 | 3390 |
| 18 | 6IP6|1|1A+6IP6|1|1C | Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii) | ELECTRON MICROSCOPY | 4.5 | 3667 |
| 19 | 6IP5|1|1A+6IP5|1|1C | Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii) | ELECTRON MICROSCOPY | 3.9 | 3717 |
| 20 | 6IP8|1|1A+6IP8|1|1C | Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv) | ELECTRON MICROSCOPY | 3.9 | 3667 |
| 21 | 5LKS|1|L5+5LKS|1|L8 | Structure-function insights reveal the human ribosome as a cancer target for antibiotics | ELECTRON MICROSCOPY | 3.6 | 3776 |
| 22 | 5T2C|1|A+5T2C|1|C | CryoEM structure of the human ribosome at 3.6 Angstrom resolution | ELECTRON MICROSCOPY | 3.6 | 3776 |
| 23 | 4UG0|1|L5+4UG0|1|L8 | STRUCTURE OF THE HUMAN 80S RIBOSOME | ELECTRON MICROSCOPY | 3.6 | 3776 |
| 24 | 4V6X|1|A5+4V6X|1|A8 | Structure of the human 80S ribosome | ELECTRON MICROSCOPY | 5 | 4298 |
| 25 | 5AJ0|1|A2+5AJ0|1|A3 | Cryo electron microscopy of actively translating human polysomes (POST state). | ELECTRON MICROSCOPY | 3.5 | 3612 |
| 26 | 6OLG|1|A2+6OLG|1|A3 | Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA) | ELECTRON MICROSCOPY | 3.4 | 3612 |
| 27 | 6OLZ|1|A2+6OLZ|1|A3 | Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA | ELECTRON MICROSCOPY | 3.9 | 3643 |
| 28 | 6OM7|1|t+6OM7|1|D | Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs | ELECTRON MICROSCOPY | 3.7 | 3607 |
| 29 | 6OLF|1|t+6OLF|1|D | Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs | ELECTRON MICROSCOPY | 3.9 | 3607 |
| 30 | 6OLE|1|t+6OLE|1|D | Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs | ELECTRON MICROSCOPY | 3.1 | 3607 |
| 31 | 6OLI|1|t+6OLI|1|D | Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC) | ELECTRON MICROSCOPY | 3.5 | 3607 |
| 32 | 6OM0|1|t+6OM0|1|D | Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs | ELECTRON MICROSCOPY | 3.1 | 3607 |
| 33 | 6W6L|1|t+6W6L|1|D | Cryo-EM structure of the human ribosome-TMCO1 translocon | ELECTRON MICROSCOPY | 3.84 | 3510 |
| 34 | 6LSS|1|2+6LSS|1|8 | Cryo-EM structure of a pre-60S ribosomal subunit - state preA | ELECTRON MICROSCOPY | 3.23 | 3383 |
| 35 | 6LU8|1|2+6LU8|1|8 | Cryo-EM structure of a human pre-60S ribosomal subunit - state A | ELECTRON MICROSCOPY | 3.13 | 3386 |
| 36 | 6LSR|1|2+6LSR|1|8 | Cryo-EM structure of a pre-60S ribosomal subunit - state B | ELECTRON MICROSCOPY | 3.13 | 3384 |
| 37 | 6SXO|1|L5 | Cryo-EM structure of the human Ebp1-ribosome complex | ELECTRON MICROSCOPY | 3.3 | 268 |