RNA 3D Hub //

Equivalence class NR_3.5_65061.17 Obsolete

#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. ÅDate
18A3D|1|A+ 8A3D|1|C (rep)Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human mature large subunit of the ribosome with eIF6 and homoharringtonine boundElectron microscopy1.672023-03-08
26ZMI|1|L5+ 6ZMI|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complexElectron microscopy2.62020-08-19
37OW7|1|A+ 7OW7|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002EIF6-bound large subunit of the human ribosomeElectron microscopy2.22022-10-05
46ZM7|1|L5+ 6ZM7|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complexElectron microscopy2.72020-07-29
57F5S|1|L5+ 7F5S|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human delta-METTL18 60S ribosomeElectron microscopy2.722022-06-22
66Y6X|1|L5+ 6Y6X|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Tetracenomycin X bound to the human ribosomeElectron microscopy2.82020-07-08
76Z6N|1|L5+ 6Z6N|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)Electron microscopy2.92020-07-29
86QZP|1|L5+ 6QZP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA (3773-MER), 5.8S rRNA (156-MER)Homo sapiensEukaryaRF02543 + RF00002High-resolution cryo-EM structure of the human 80S ribosomeElectron microscopy2.92019-04-24
96ZME|1|L5+ 6ZME|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complexElectron microscopy32020-08-12
106Z6L|1|L5+ 6Z6L|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human CCDC124 bound to 80S ribosomesElectron microscopy32020-07-29
117QVP|1|L5+ 7QVP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human collided disome (di-ribosome) stalled on XBP1 mRNAElectron microscopy32022-10-12
127QVP|1|L6+ 7QVP|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human collided disome (di-ribosome) stalled on XBP1 mRNAElectron microscopy32022-10-12
136XA1|1|L5+ 6XA1|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Structure of a drug-like compound stalled human translation termination complexElectron microscopy2.82020-10-07
146ZMO|1|L5+ 6ZMO|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complexElectron microscopy3.12020-08-19
156Z6M|1|L5+ 6Z6M|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1Electron microscopy3.12020-07-29
166OLE|1|t+ 6OLE|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAsElectron microscopy3.12019-06-19
176OM0|1|t+ 6OM0|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAsElectron microscopy3.12019-06-19
186Y2L|1|L5+ 6Y2L|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in POST stateElectron microscopy32020-04-15
196LQM|1|2+ 6LQM|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state CElectron microscopy3.092020-08-26
206Y0G|1|L5+ 6Y0G|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in classical-PRE stateElectron microscopy3.22020-04-15
217BHP|1|L5+ 7BHP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human Ebp1 - 80S ribosomeElectron microscopy3.32021-02-03
226LU8|1|2+ 6LU8|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a human pre-60S ribosomal subunit - state AElectron microscopy3.132020-08-26
236LSR|1|2+ 6LSR|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state BElectron microscopy3.132020-08-26
246LSS|1|2+ 6LSS|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state preAElectron microscopy3.232020-08-26
256OLI|1|t+ 6OLI|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)Electron microscopy3.52019-06-19
266OLG|1|A2+ 6OLG|1|A3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)Electron microscopy3.42019-06-19
276Y57|1|L5+ 6Y57|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in hybrid-PRE stateElectron microscopy3.52020-04-15
285AJ0|1|A2+ 5AJ0|1|A3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo electron microscopy of actively translating human polysomes (POST state).Electron microscopy3.52015-05-20
296SXO|1|L5Large subunit ribosomal RNA28S ribosomal RNA including ES27L-B (2839-3265)Homo sapiensEukaryaRF02543Cryo-EM structure of the human Ebp1-ribosome complexElectron microscopy3.32020-02-19

Release history

Release3.2733.2743.2753.276
Date2023-03-082023-03-152023-03-222023-03-29

Parents

This classParent classesRelease idIntersectionAdded to this classOnly in parent
NR_3.5_65061.17NR_3.5_65061.163.273(28) 7F5S|1|L5+7F5S|1|L8, 7BHP|1|L5+7BHP|1|L8, 6ZMO|1|L5+6ZMO|1|L8, 6ZMI|1|L5+6ZMI|1|L8, 6ZME|1|L5+6ZME|1|L8, 6ZM7|1|L5+6ZM7|1|L8, 6Z6N|1|L5+6Z6N|1|L8, 6Z6M|1|L5+6Z6M|1|L8, 6Z6L|1|L5+6Z6L|1|L8, 6Y6X|1|L5+6Y6X|1|L8, 6Y57|1|L5+6Y57|1|L8, 6Y2L|1|L5+6Y2L|1|L8, 6Y0G|1|L5+6Y0G|1|L8, 6XA1|1|L5+6XA1|1|L8, 6SXO|1|L5, 6QZP|1|L5+6QZP|1|L8, 6OM0|1|t+6OM0|1|D, 6OLI|1|t+6OLI|1|D, 6OLG|1|A2+6OLG|1|A3, 6OLE|1|t+6OLE|1|D, 6LU8|1|2+6LU8|1|8, 6LSS|1|2+6LSS|1|8, 6LSR|1|2+6LSR|1|8, 6LQM|1|2+6LQM|1|8, 5AJ0|1|A2+5AJ0|1|A3, 7QVP|1|L6+7QVP|1|L1, 7QVP|1|L5+7QVP|1|L8, 7OW7|1|A+7OW7|1|C(1) 8A3D|1|A+8A3D|1|C(0)

Children

This class Descendant classesRelease idIntersectionOnly in this classAdded to child
NR_3.5_65061.17NR_3.5_65061.183.277(29) 5AJ0|1|A2+5AJ0|1|A3, 6OM0|1|t+6OM0|1|D, 6Z6L|1|L5+6Z6L|1|L8, 7F5S|1|L5+7F5S|1|L8, 6OLI|1|t+6OLI|1|D, 6Y6X|1|L5+6Y6X|1|L8, 7BHP|1|L5+7BHP|1|L8, 6OLG|1|A2+6OLG|1|A3, 6Y57|1|L5+6Y57|1|L8, 6ZMO|1|L5+6ZMO|1|L8, 6OLE|1|t+6OLE|1|D, 6Y2L|1|L5+6Y2L|1|L8, 6ZMI|1|L5+6ZMI|1|L8, 8A3D|1|A+8A3D|1|C, 6LU8|1|2+6LU8|1|8, 6Y0G|1|L5+6Y0G|1|L8, 6ZME|1|L5+6ZME|1|L8, 7QVP|1|L6+7QVP|1|L1, 6LSS|1|2+6LSS|1|8, 6XA1|1|L5+6XA1|1|L8, 6ZM7|1|L5+6ZM7|1|L8, 6LSR|1|2+6LSR|1|8, 6SXO|1|L5, 6Z6N|1|L5+6Z6N|1|L8, 7QVP|1|L5+7QVP|1|L8, 6LQM|1|2+6LQM|1|8, 6QZP|1|L5+6QZP|1|L8, 6Z6M|1|L5+6Z6M|1|L8, 7OW7|1|A+7OW7|1|C(0) (2) 7XNX|1|L1+7XNX|1|L3, 7XNY|1|L1+7XNY|1|L3

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. Instances are ordered to put similar structures near each other. The colorbar ranges from 0 to the maximum observed discrepancy, up to 0.5

#S - ordering by similarity (same as in the heat map).
#SPDBTitleMethodResolutionLength
15AJ0|1|A2+5AJ0|1|A3Cryo electron microscopy of actively translating human polysomes (POST state).ELECTRON MICROSCOPY3.53612
26OLG|1|A2+6OLG|1|A3Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)ELECTRON MICROSCOPY3.43612
36OLI|1|t+6OLI|1|DStructure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)ELECTRON MICROSCOPY3.53607
46OLE|1|t+6OLE|1|DHuman ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAsELECTRON MICROSCOPY3.13607
56OM0|1|t+6OM0|1|DHuman ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAsELECTRON MICROSCOPY3.13607
66LSS|1|2+6LSS|1|8Cryo-EM structure of a pre-60S ribosomal subunit - state preAELECTRON MICROSCOPY3.233383
76LU8|1|2+6LU8|1|8Cryo-EM structure of a human pre-60S ribosomal subunit - state AELECTRON MICROSCOPY3.133386
86XA1|1|L5+6XA1|1|L8Structure of a drug-like compound stalled human translation termination complexELECTRON MICROSCOPY2.83390
97OW7|1|A+7OW7|1|CEIF6-bound large subunit of the human ribosomeELECTRON MICROSCOPY2.23190
108A3D|1|A+8A3D|1|CHuman mature large subunit of the ribosome with eIF6 and homoharringtonine boundELECTRON MICROSCOPY1.673190
117F5S|1|L5+7F5S|1|L8human delta-METTL18 60S ribosomeELECTRON MICROSCOPY2.723575
126QZP|1|L5+6QZP|1|L8High-resolution cryo-EM structure of the human 80S ribosomeELECTRON MICROSCOPY2.93696
137QVP|1|L5+7QVP|1|L8Human collided disome (di-ribosome) stalled on XBP1 mRNAELECTRON MICROSCOPY33611
146Y2L|1|L5+6Y2L|1|L8Structure of human ribosome in POST stateELECTRON MICROSCOPY33613
156Y0G|1|L5+6Y0G|1|L8Structure of human ribosome in classical-PRE stateELECTRON MICROSCOPY3.23644
166Y57|1|L5+6Y57|1|L8Structure of human ribosome in hybrid-PRE stateELECTRON MICROSCOPY3.53574
177QVP|1|L6+7QVP|1|L1Human collided disome (di-ribosome) stalled on XBP1 mRNAELECTRON MICROSCOPY33572
186Z6M|1|L5+6Z6M|1|L8Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1ELECTRON MICROSCOPY3.13772
196ZME|1|L5+6ZME|1|L8SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complexELECTRON MICROSCOPY33773
206ZMO|1|L5+6ZMO|1|L8SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complexELECTRON MICROSCOPY3.13773
216ZMI|1|L5+6ZMI|1|L8SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complexELECTRON MICROSCOPY2.63773
226ZM7|1|L5+6ZM7|1|L8SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complexELECTRON MICROSCOPY2.73773
236Z6L|1|L5+6Z6L|1|L8Cryo-EM structure of human CCDC124 bound to 80S ribosomesELECTRON MICROSCOPY33772
246Z6N|1|L5+6Z6N|1|L8Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)ELECTRON MICROSCOPY2.93772
256Y6X|1|L5+6Y6X|1|L8Tetracenomycin X bound to the human ribosomeELECTRON MICROSCOPY2.83773
267BHP|1|L5+7BHP|1|L8Cryo-EM structure of the human Ebp1 - 80S ribosomeELECTRON MICROSCOPY3.33644
276LQM|1|2+6LQM|1|8Cryo-EM structure of a pre-60S ribosomal subunit - state CELECTRON MICROSCOPY3.093433
286LSR|1|2+6LSR|1|8Cryo-EM structure of a pre-60S ribosomal subunit - state BELECTRON MICROSCOPY3.133384
296SXO|1|L5Cryo-EM structure of the human Ebp1-ribosome complexELECTRON MICROSCOPY3.3268
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