#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. ÅDate
18GLP|1|L5+ 8GLP|1|L8 (rep)Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)Electron microscopy1.672023-04-19
28A3D|1|A+ 8A3D|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human mature large subunit of the ribosome with eIF6 and homoharringtonine boundElectron microscopy1.672023-03-08
38G5Y|1|L5+ 8G5Y|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)Electron microscopy2.292023-04-19
47XNY|1|L1+ 7XNY|1|L3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsElectron microscopy2.52023-04-05
56ZMI|1|L5+ 6ZMI|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complexElectron microscopy2.62020-08-19
67OW7|1|A+ 7OW7|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002EIF6-bound large subunit of the human ribosomeElectron microscopy2.22022-10-05
76ZM7|1|L5+ 6ZM7|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complexElectron microscopy2.72020-07-29
88G60|1|L5+ 8G60|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)Electron microscopy2.542023-04-19
97XNX|1|L1+ 7XNX|1|L3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cellsElectron microscopy2.72023-04-05
108G5Z|1|L5+ 8G5Z|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)Electron microscopy2.642023-04-19
117F5S|1|L5+ 7F5S|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human delta-METTL18 60S ribosomeElectron microscopy2.722022-06-22
126Y6X|1|L5+ 6Y6X|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Tetracenomycin X bound to the human ribosomeElectron microscopy2.82020-07-08
136Z6N|1|L5+ 6Z6N|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)Electron microscopy2.92020-07-29
148G6J|1|L5+ 8G6J|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)Electron microscopy2.82023-04-19
156QZP|1|L5+ 6QZP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA (3773-MER), 5.8S rRNA (156-MER)Homo sapiensEukaryaRF02543 + RF00002High-resolution cryo-EM structure of the human 80S ribosomeElectron microscopy2.92019-04-24
166ZME|1|L5+ 6ZME|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complexElectron microscopy32020-08-12
176Z6L|1|L5+ 6Z6L|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human CCDC124 bound to 80S ribosomesElectron microscopy32020-07-29
187QVP|1|L5+ 7QVP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human collided disome (di-ribosome) stalled on XBP1 mRNAElectron microscopy32022-10-12
197QVP|1|L6+ 7QVP|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human collided disome (di-ribosome) stalled on XBP1 mRNAElectron microscopy32022-10-12
206XA1|1|L5+ 6XA1|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Structure of a drug-like compound stalled human translation termination complexElectron microscopy2.82020-10-07
216ZMO|1|L5+ 6ZMO|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complexElectron microscopy3.12020-08-19
226Z6M|1|L5+ 6Z6M|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1Electron microscopy3.12020-07-29
238G61|1|L5+ 8G61|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)Electron microscopy2.942023-04-19
246OLE|1|t+ 6OLE|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAsElectron microscopy3.12019-06-19
256OM0|1|t+ 6OM0|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAsElectron microscopy3.12019-06-19
266Y2L|1|L5+ 6Y2L|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in POST stateElectron microscopy32020-04-15
276LQM|1|2+ 6LQM|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state CElectron microscopy3.092020-08-26
286Y0G|1|L5+ 6Y0G|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in classical-PRE stateElectron microscopy3.22020-04-15
297BHP|1|L5+ 7BHP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human Ebp1 - 80S ribosomeElectron microscopy3.32021-02-03
306LU8|1|2+ 6LU8|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a human pre-60S ribosomal subunit - state AElectron microscopy3.132020-08-26
316LSR|1|2+ 6LSR|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state BElectron microscopy3.132020-08-26
326LSS|1|2+ 6LSS|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state preAElectron microscopy3.232020-08-26
336OLI|1|t+ 6OLI|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)Electron microscopy3.52019-06-19
346OLG|1|A2+ 6OLG|1|A3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)Electron microscopy3.42019-06-19
356Y57|1|L5+ 6Y57|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in hybrid-PRE stateElectron microscopy3.52020-04-15
365AJ0|1|A2+ 5AJ0|1|A3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo electron microscopy of actively translating human polysomes (POST state).Electron microscopy3.52015-05-20
376SXO|1|L5Large subunit ribosomal RNA28S ribosomal RNA including ES27L-B (2839-3265)Homo sapiensEukaryaRF02543Cryo-EM structure of the human Ebp1-ribosome complexElectron microscopy3.32020-02-19

Release history

Release3.2793.2803.2813.2823.2833.2843.2853.2863.2873.2883.2893.290
Date2023-04-192023-04-262023-05-032023-05-102023-05-172023-05-242023-05-312023-06-072023-06-142023-06-212023-06-282023-07-05

Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well.

#SPDBTitleMethodResolutionLength
1
6LSS|1|2+6LSS|1|8
Cryo-EM structure of a pre-60S ribosomal subunit - state preAELECTRON MICROSCOPY3.233383
2
6LU8|1|2+6LU8|1|8
Cryo-EM structure of a human pre-60S ribosomal subunit - state AELECTRON MICROSCOPY3.133386
3
5AJ0|1|A2+5AJ0|1|A3
Cryo electron microscopy of actively translating human polysomes (POST state).ELECTRON MICROSCOPY3.53612
4
6OLG|1|A2+6OLG|1|A3
Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)ELECTRON MICROSCOPY3.43612
5
6OLI|1|t+6OLI|1|D
Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)ELECTRON MICROSCOPY3.53607
6
6OLE|1|t+6OLE|1|D
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAsELECTRON MICROSCOPY3.13607
7
6OM0|1|t+6OM0|1|D
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAsELECTRON MICROSCOPY3.13607
8
8G6J|1|L5+8G6J|1|L8
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)ELECTRON MICROSCOPY2.83559
9
8G5Z|1|L5+8G5Z|1|L8
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)ELECTRON MICROSCOPY2.643560
10
8G61|1|L5+8G61|1|L8
mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)ELECTRON MICROSCOPY2.943528
11
8G5Y|1|L5+8G5Y|1|L8
mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)ELECTRON MICROSCOPY2.293594
12
8GLP|1|L5+8GLP|1|L8
mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)ELECTRON MICROSCOPY1.673418
13
8G60|1|L5+8G60|1|L8
mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)ELECTRON MICROSCOPY2.543509
14
8A3D|1|A+8A3D|1|C
Human mature large subunit of the ribosome with eIF6 and homoharringtonine boundELECTRON MICROSCOPY1.673190
15
7OW7|1|A+7OW7|1|C
EIF6-bound large subunit of the human ribosomeELECTRON MICROSCOPY2.23190
16
7F5S|1|L5+7F5S|1|L8
human delta-METTL18 60S ribosomeELECTRON MICROSCOPY2.723575
17
6QZP|1|L5+6QZP|1|L8
High-resolution cryo-EM structure of the human 80S ribosomeELECTRON MICROSCOPY2.93696
18
6Y0G|1|L5+6Y0G|1|L8
Structure of human ribosome in classical-PRE stateELECTRON MICROSCOPY3.23644
19
6Y2L|1|L5+6Y2L|1|L8
Structure of human ribosome in POST stateELECTRON MICROSCOPY33613
20
7QVP|1|L5+7QVP|1|L8
Human collided disome (di-ribosome) stalled on XBP1 mRNAELECTRON MICROSCOPY33611
21
7QVP|1|L6+7QVP|1|L1
Human collided disome (di-ribosome) stalled on XBP1 mRNAELECTRON MICROSCOPY33572
22
6Y57|1|L5+6Y57|1|L8
Structure of human ribosome in hybrid-PRE stateELECTRON MICROSCOPY3.53574
23
6Y6X|1|L5+6Y6X|1|L8
Tetracenomycin X bound to the human ribosomeELECTRON MICROSCOPY2.83773
24
6Z6N|1|L5+6Z6N|1|L8
Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)ELECTRON MICROSCOPY2.93772
25
6Z6L|1|L5+6Z6L|1|L8
Cryo-EM structure of human CCDC124 bound to 80S ribosomesELECTRON MICROSCOPY33772
26
6ZM7|1|L5+6ZM7|1|L8
SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complexELECTRON MICROSCOPY2.73773
27
6ZMI|1|L5+6ZMI|1|L8
SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complexELECTRON MICROSCOPY2.63773
28
6ZMO|1|L5+6ZMO|1|L8
SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complexELECTRON MICROSCOPY3.13773
29
6ZME|1|L5+6ZME|1|L8
SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complexELECTRON MICROSCOPY33773
30
6Z6M|1|L5+6Z6M|1|L8
Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1ELECTRON MICROSCOPY3.13772
31
7XNX|1|L1+7XNX|1|L3
High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cellsELECTRON MICROSCOPY2.73686
32
7XNY|1|L1+7XNY|1|L3
High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsELECTRON MICROSCOPY2.53686
33
7BHP|1|L5+7BHP|1|L8
Cryo-EM structure of the human Ebp1 - 80S ribosomeELECTRON MICROSCOPY3.33644
34
6XA1|1|L5+6XA1|1|L8
Structure of a drug-like compound stalled human translation termination complexELECTRON MICROSCOPY2.83390
35
6LQM|1|2+6LQM|1|8
Cryo-EM structure of a pre-60S ribosomal subunit - state CELECTRON MICROSCOPY3.093433
36
6LSR|1|2+6LSR|1|8
Cryo-EM structure of a pre-60S ribosomal subunit - state BELECTRON MICROSCOPY3.133384
37
6SXO|1|L5
Cryo-EM structure of the human Ebp1-ribosome complexELECTRON MICROSCOPY3.3268

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


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