#IFECompound(s)RNA source organismTitleMethodResolutionDate
15TBW|1|AS (rep)5S ribosomal RNASaccharomyces cerevisiaeCrystal structure of chlorolissoclimide bound to the yeast 80S ribosomeX-RAY DIFFRACTION32017-07-26
25TBW|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of chlorolissoclimide bound to the yeast 80S ribosomeX-RAY DIFFRACTION32017-07-26
34V88|1|A35S rRNASaccharomyces cerevisiaeThe structure of the eukaryotic ribosome at 3.0 A resolution.X-RAY DIFFRACTION32014-07-09
44V88|1|A75S rRNASaccharomyces cerevisiaeThe structure of the eukaryotic ribosome at 3.0 A resolution.X-RAY DIFFRACTION32014-07-09
57OSA|1|AB5SSaccharomyces cerevisiaePre-translocation complex of 80 S.cerevisiae ribosome with eEF2 and ligandsX-RAY DIFFRACTION32021-12-08
65I4L|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Amicoumacin A bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.12016-06-22
76HHQ|1|AS5S ribosomal RNASaccharomyces cerevisiaeCrystal structure of compound C45 bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.12019-02-20
85MEI|1|AS5S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Agelastatin A bound to the 80S ribosomeX-RAY DIFFRACTION3.52017-06-28
95MEI|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Agelastatin A bound to the 80S ribosomeX-RAY DIFFRACTION3.52017-06-28
105OBM|1|75S Ribosomal RNASaccharomyces cerevisiaeCrystal structure of Gentamicin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.42017-12-13
116HHQ|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of compound C45 bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.12019-02-20
125LYB|1|75S rRNASaccharomyces cerevisiaeCrystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCPmnX-RAY DIFFRACTION3.252016-11-23
135ON6|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of haemanthamine bound to the 80S ribosomeX-RAY DIFFRACTION3.12018-02-28
145I4L|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Amicoumacin A bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.12016-06-22
155ON6|1|AS5S ribosomal RNASaccharomyces cerevisiaeCrystal structure of haemanthamine bound to the 80S ribosomeX-RAY DIFFRACTION3.12018-02-28
165LYB|1|35S rRNASaccharomyces cerevisiaeCrystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCPmnX-RAY DIFFRACTION3.252016-11-23
175OBM|1|35S Ribosomal RNASaccharomyces cerevisiaeCrystal structure of Gentamicin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.42017-12-13
185NDW|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of aminoglycoside TC007 bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.72017-12-13
197OSM|1|AB5S rRNASaccharomyces cerevisiaeIntermediate translocation complex of 80 S.cerevisiae ribosome with eEF2 and ligandsX-RAY DIFFRACTION32021-12-08
205NDW|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of aminoglycoside TC007 bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.72017-12-13
215NDV|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Paromomycin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.32017-12-13
225NDV|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Paromomycin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.32017-12-13
235NDG|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of geneticin (G418) bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.72017-12-13
245NDG|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of geneticin (G418) bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.72017-12-13
255TGM|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-ProX-RAY DIFFRACTION3.52017-01-18
265TGM|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-ProX-RAY DIFFRACTION3.52017-01-18
274V7R|1|B25S ribosomal RNASaccharomyces cerevisiaeYeast 80S ribosome.X-RAY DIFFRACTION42014-07-09
284V7R|1|D25S ribosomal RNASaccharomyces cerevisiaeYeast 80S ribosome.X-RAY DIFFRACTION42014-07-09
295DAT|1|75S ribosomal RNASaccharomyces cerevisiaeComplex of yeast 80S ribosome with hypusine-containing eIF5AX-RAY DIFFRACTION3.152016-08-31
305DGV|1|75S ribosomal RNASaccharomyces cerevisiaeComplex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analogX-RAY DIFFRACTION3.12016-12-14
315DGF|1|75S ribosomal RNASaccharomyces cerevisiaeComplex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analogX-RAY DIFFRACTION3.32016-12-14
325DAT|1|35S ribosomal RNASaccharomyces cerevisiaeComplex of yeast 80S ribosome with hypusine-containing eIF5AX-RAY DIFFRACTION3.152016-08-31
335DGE|1|75S ribosomal RNASaccharomyces cerevisiaeCoping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosomeX-RAY DIFFRACTION3.452017-01-25
345DGV|1|35S ribosomal RNASaccharomyces cerevisiaeComplex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analogX-RAY DIFFRACTION3.12016-12-14
355TGA|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-ProX-RAY DIFFRACTION3.32016-11-23
365DC3|1|75S ribosomal RNASaccharomyces cerevisiaeComplex of yeast 80S ribosome with non-modified eIF5AX-RAY DIFFRACTION3.252016-06-01
375DGE|1|35S ribosomal RNASaccharomyces cerevisiaeCoping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosomeX-RAY DIFFRACTION3.452017-01-25
385DC3|1|35S ribosomal RNASaccharomyces cerevisiaeComplex of yeast 80S ribosome with non-modified eIF5AX-RAY DIFFRACTION3.252016-06-01
395TGA|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-ProX-RAY DIFFRACTION3.32016-11-23
405DGF|1|35S ribosomal RNASaccharomyces cerevisiaeComplex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analogX-RAY DIFFRACTION3.32016-12-14
416T4Q|1|C45S rRNASaccharomyces cerevisiaeStructure of yeast 80S ribosome stalled on the CGA-CCG inhibitory codon combination.ELECTRON MICROSCOPY2.62019-12-25
427MPJ|1|A35S rRNASaccharomyces cerevisiaeStm1 bound vacant 80S structure isolated from nop1-D243AELECTRON MICROSCOPY2.72022-05-11
436TB3|1|BR5S rRNASaccharomyces cerevisiaeyeast 80S ribosome in complex with the Not5 subunit of the CCR4-NOT complexELECTRON MICROSCOPY2.82020-04-22
446SNT|1|45S rRNASaccharomyces cerevisiaeYeast 80S ribosome stalled on SDD1 mRNA.ELECTRON MICROSCOPY2.82020-03-04
457AZY|1|F5S ribosomal RNASaccharomyces cerevisiae S288CContext-specific inhibition of eukaryotic translation by macrolide antibioticsELECTRON MICROSCOPY2.8772021-05-19
464U4R|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Lactimidomycin bound to the yeast 80S ribosomeX-RAY DIFFRACTION2.82014-10-22
474U3U|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Cycloheximide bound to the yeast 80S ribosomeX-RAY DIFFRACTION2.92014-10-22
486WOO|1|75S ribosomal RNASaccharomyces cerevisiaeCryoEM structure of yeast 80S ribosome with Met-tRNAiMet, eIF5B, and GDPELECTRON MICROSCOPY2.92020-09-23
494U4R|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Lactimidomycin bound to the yeast 80S ribosomeX-RAY DIFFRACTION2.82014-10-22
504U3U|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Cycloheximide bound to the yeast 80S ribosomeX-RAY DIFFRACTION2.92014-10-22
517N8B|1|A35SSaccharomyces cerevisiaeCycloheximide bound vacant 80S structure isolated from cbf5-D95AELECTRON MICROSCOPY3.052022-05-11
527MPI|1|A35s rRNASaccharomyces cerevisiaeStm1 bound vacant 80S structure isolated from cbf5-D95AELECTRON MICROSCOPY3.052022-05-11
534U4Q|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Homoharringtonine bound to the yeast 80S ribosomeX-RAY DIFFRACTION32014-10-22
544U4Q|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Homoharringtonine bound to the yeast 80S ribosomeX-RAY DIFFRACTION32014-10-22
554U3M|1|75.8s rRNASaccharomyces cerevisiaeCrystal structure of Anisomycin bound to the yeast 80S ribosomeX-RAY DIFFRACTION32014-10-22
564U52|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Nagilactone C bound to the yeast 80S ribosomeX-RAY DIFFRACTION32014-10-22
574U3M|1|35.8s rRNASaccharomyces cerevisiaeCrystal structure of Anisomycin bound to the yeast 80S ribosomeX-RAY DIFFRACTION32014-10-22
586QIK|1|x5S ribosomal RNASaccharomyces cerevisiaeCryo-EM structures of Lsg1-TAP pre-60S ribosomal particlesELECTRON MICROSCOPY3.12019-06-26
597OHQ|1|35S rRNASaccharomyces cerevisiae S288CNog1-TAP associated immature ribosomal particle population C from S. cerevisiaeELECTRON MICROSCOPY3.12021-11-03
604U4U|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Lycorine bound to the yeast 80S ribosomeX-RAY DIFFRACTION32014-10-22
617BT6|1|3RDN5-2 rRNASaccharomyces cerevisiaeCryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.12 Angstroms resolution(state R1)ELECTRON MICROSCOPY3.122020-10-28
626Q8Y|1|BR5S ribosomal RNASaccharomyces cerevisiaeCryo-EM structure of the mRNA translating and degrading yeast 80S ribosome-Xrn1 nuclease complexELECTRON MICROSCOPY3.12019-03-13
636YLG|1|35S rRNASaccharomyces cerevisiaeRix1-Rea1 pre-60S particle - 60S core, body 1 (rigid body refinement)ELECTRON MICROSCOPY32020-07-29
644U6F|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of T-2 toxin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.12014-10-22
655T62|1|B5S Ribosomal RNASaccharomyces cerevisiaeNmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis: 60S-Nmd3-Tif6-Lsg1 ComplexELECTRON MICROSCOPY3.12017-02-08
664U52|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Nagilactone C bound to the yeast 80S ribosomeX-RAY DIFFRACTION32014-10-22
674U4U|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Lycorine bound to the yeast 80S ribosomeX-RAY DIFFRACTION32014-10-22
686T7T|1|C45S rRNASaccharomyces cerevisiaeStructure of yeast 80S ribosome stalled on poly(A) tract.ELECTRON MICROSCOPY3.12019-12-25
696XIR|1|35S ribosomal RNASaccharomyces cerevisiaeCryo-EM Structure of K63 Ubiquitinated Yeast Translocating Ribosome under Oxidative StressELECTRON MICROSCOPY3.22020-08-26
706RZZ|1|x5S ribosomal RNASaccharomyces cerevisiaeCryo-EM structures of Lsg1-TAP pre-60S ribosomal particlesELECTRON MICROSCOPY3.22019-06-26
716M62|1|3RDN5-2 rRNASaccharomyces cerevisiaeCryo-Em structure of eukaryotic pre-60S ribosome subunit from Saccharomyces cerevisiae rpf2 delta 255-344 strain, C4 state.ELECTRON MICROSCOPY3.22020-08-26
727BTB|1|3RDN5-2 rRNASaccharomyces cerevisiaeCryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.22 Angstroms resolution(state R2)ELECTRON MICROSCOPY3.222020-10-28
737RR5|1|C45S rRNASaccharomyces cerevisiaeStructure of ribosomal complex bound with Rbg1/Tma46ELECTRON MICROSCOPY3.232021-11-10
746YLH|1|35S rRNASaccharomyces cerevisiaeRix1-Rea1 pre-60S particle - full composite structureELECTRON MICROSCOPY3.12020-07-29
754U4N|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Edeine bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.12014-10-22
764U6F|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of T-2 toxin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.12014-10-22
776TNU|1|BR5S rRNASaccharomyces cerevisiaeYeast 80S ribosome in complex with eIF5A and decoding A-site and P-site tRNAs.ELECTRON MICROSCOPY3.12020-04-22
783JCT|1|3RDN5-2 rRNASaccharomyces cerevisiaeCryo-em structure of eukaryotic pre-60S ribosomal subunitsELECTRON MICROSCOPY3.082016-06-01
794U3N|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of CCA trinucleotide bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.22014-10-22
804U4Z|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Phyllanthoside bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.12014-10-22
814U4N|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Edeine bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.12014-10-22
826T7I|1|C45S ribosomal RNASaccharomyces cerevisiaeStructure of yeast 80S ribosome stalled on the CGA-CGA inhibitory codon combination.ELECTRON MICROSCOPY3.22019-12-25
837B7D|1|LB5S rRNASaccharomyces cerevisiae S288CYeast 80S ribosome bound to eEF3 and A/A- and P/P-tRNAsELECTRON MICROSCOPY3.32021-03-10
846RI5|1|x5S rRNASaccharomyces cerevisiaeCryo-EM structures of Lsg1-TAP pre-60S ribosomal particlesELECTRON MICROSCOPY3.32019-06-26
856S47|1|AB5S ribosomal RNASaccharomyces cerevisiaeSaccharomyces cerevisiae 80S ribosome bound with ABCF protein New1ELECTRON MICROSCOPY3.282019-07-24
864U4Z|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Phyllanthoside bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.12014-10-22
874U55|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Cryptopleurine bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.22014-10-22
884U50|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Verrucarin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.22014-10-22
895M1J|1|345S ribosomal RNASaccharomyces cerevisiaeNonstop ribosomal complex bound with Dom34 and Hbs1ELECTRON MICROSCOPY3.32017-01-18
904U50|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Verrucarin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.22014-10-22
914U3N|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of CCA trinucleotide bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.22014-10-22
924U4Y|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Pactamycin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.22014-10-22
934U4Y|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Pactamycin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.22014-10-22
944U51|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Narciclasine bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.22014-10-22
956Z6K|1|C45S rRNASaccharomyces cerevisiaeCryo-EM structure of yeast reconstituted Lso2 bound to 80S ribosomesELECTRON MICROSCOPY3.42020-07-29
966Z6J|1|C45S rRNASaccharomyces cerevisiaeCryo-EM structure of yeast Lso2 bound to 80S ribosomes under native conditionELECTRON MICROSCOPY3.42020-07-29
976QT0|1|x5S rRNASaccharomyces cerevisiaeCryo-EM structures of Lsg1-TAP pre-60S ribosomal particlesELECTRON MICROSCOPY3.42019-06-26
987OH3|1|35S rRNASaccharomyces cerevisiae S288CNog1-TAP associated immature ribosomal particle population B from S. cerevisiaeELECTRON MICROSCOPY3.42021-11-03
994U55|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Cryptopleurine bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.22014-10-22
1005H4P|1|35S ribosomal RNASaccharomyces cerevisiaeStructural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1, Tif6 and Reh1ELECTRON MICROSCOPY3.072017-01-25
1016SV4|1|YR5S rRNASaccharomyces cerevisiaeThe cryo-EM structure of SDD1-stalled collided trisome.ELECTRON MICROSCOPY3.32020-03-04
1026SV4|1|ZR5S rRNASaccharomyces cerevisiaeThe cryo-EM structure of SDD1-stalled collided trisome.ELECTRON MICROSCOPY3.32020-03-04
1034U53|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Deoxynivalenol bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.32014-10-22
1045APO|1|75S ribosomal RNASaccharomyces cerevisiaeStructure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and C-terminally tagged Rei1ELECTRON MICROSCOPY3.412015-12-16
1056QTZ|1|x5S rRNASaccharomyces cerevisiaeCryo-EM structures of Lsg1-TAP pre-60S ribosomal particlesELECTRON MICROSCOPY3.52019-06-26
1066R86|1|35S ribosomal RNASaccharomyces cerevisiaeYeast Vms1-60S ribosomal subunit complex (post-state)ELECTRON MICROSCOPY3.42019-07-31
1076N8M|1|B5S rRNASaccharomyces cerevisiaeCryo-EM structure of pre-Lsg1 (PL) pre-60S ribosomal subunitELECTRON MICROSCOPY3.52019-03-13
1084U51|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Narciclasine bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.22014-10-22
1094U53|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Deoxynivalenol bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.32014-10-22
1106SV4|1|BR5S rRNASaccharomyces cerevisiaeThe cryo-EM structure of SDD1-stalled collided trisome.ELECTRON MICROSCOPY3.32020-03-04
1116N8O|1|B5S rRNASaccharomyces cerevisiaeCryo-EM structure of Rpl10-inserted (RI) pre-60S ribosomal subunitELECTRON MICROSCOPY3.52019-03-13
1126N8J|1|25S rRNASaccharomyces cerevisiaeCryo-EM structure of late nuclear (LN) pre-60S ribosomal subunitELECTRON MICROSCOPY3.52019-03-13
1136R87|1|35S rRNASaccharomyces cerevisiaeYeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state without Arb1)ELECTRON MICROSCOPY3.42019-06-26
1146HD7|1|35S rRNASaccharomyces cerevisiaeCryo-EM structure of the ribosome-NatA complexELECTRON MICROSCOPY3.42018-12-19
1155JUP|1|D5S ribosomal RNASaccharomyces cerevisiaeSaccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure II (mid-rotated 40S subunit)ELECTRON MICROSCOPY3.52016-10-05
1166N8K|1|25S rRNASaccharomyces cerevisiaeCryo-EM structure of early cytoplasmic-immediate (ECI) pre-60S ribosomal subunitELECTRON MICROSCOPY3.62019-03-13
1176N8L|1|25S rRNASaccharomyces cerevisiaeCryo-EM structure of early cytoplasmic-late (ECL) pre-60S ribosomal subunitELECTRON MICROSCOPY3.62019-03-13
1184U56|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Blasticidin S bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.452014-10-22
1196R84|1|35S rRNASaccharomyces cerevisiaeYeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state with Arb1)ELECTRON MICROSCOPY3.62019-06-26
1204U56|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Blasticidin S bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.452014-10-22
1216OIG|1|75S ribosomal RNASaccharomyces cerevisiaeSubunit joining exposes nascent pre-40S rRNA for processing and quality controlELECTRON MICROSCOPY3.82020-09-30
1226N8N|1|B5S rRNASaccharomyces cerevisiaeCryo-EM structure of Lsg1-engaged (LE) pre-60S ribosomal subunitELECTRON MICROSCOPY3.82019-03-13
1236S05|1|x5S ribosomal RNASaccharomyces cerevisiaeCryo-EM structures of Lsg1-TAP pre-60S ribosomal particlesELECTRON MICROSCOPY3.92019-06-26
1247NRC|1|LB5S rRNA (121-MER)Saccharomyces cerevisiae S288CStructure of the yeast Gcn1 bound to a leading stalled 80S ribosome with Rbg2, Gir2, A- and P-tRNA and eIF5AELECTRON MICROSCOPY3.92021-05-05
1256GQB|1|35S ribosomal RNASaccharomyces cerevisiaeCryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GDP+AlF4/sordarin)ELECTRON MICROSCOPY3.92018-07-11
1265MC6|1|BR5S ribosomal RNASaccharomyces cerevisiaeCryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiaeELECTRON MICROSCOPY3.82017-01-18
1276T83|1|Bb5S rRNASaccharomyces cerevisiaeStructure of yeast disome (di-ribosome) stalled on poly(A) tract.ELECTRON MICROSCOPY42019-12-25
1286T83|1|4b5S rRNASaccharomyces cerevisiaeStructure of yeast disome (di-ribosome) stalled on poly(A) tract.ELECTRON MICROSCOPY42019-12-25
1295JUT|1|D5S ribosomal RNASaccharomyces cerevisiaeSaccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure IV (almost non-rotated 40S subunit)ELECTRON MICROSCOPY42016-10-05
1306FT6|1|35S ribosomal RNASaccharomyces cerevisiaeStructure of the Nop53 pre-60S particle bound to the exosome nuclear cofactorsELECTRON MICROSCOPY3.92018-03-28
1315JUO|1|D5S ribosomal RNASaccharomyces cerevisiaeSaccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure I (fully rotated 40S subunit)ELECTRON MICROSCOPY42016-10-05
1325JUU|1|D5S ribosomal RNASaccharomyces cerevisiaeSaccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure V (least rotated 40S subunit)ELECTRON MICROSCOPY42016-10-05
1336GQV|1|35S ribosomal RNASaccharomyces cerevisiaeCryo-EM recosntruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP)ELECTRON MICROSCOPY42018-07-11
1345APN|1|75S rRNASaccharomyces cerevisiaeStructure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and N-terminally tagged Rei1ELECTRON MICROSCOPY3.912015-12-16
1354U4O|1|75S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Geneticin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.62014-10-22
1364U4O|1|35S ribosomal RNASaccharomyces cerevisiaeCrystal structure of Geneticin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.62014-10-22
1375GAK|1|35S rRNASaccharomyces cerevisiaeYeast 60S ribosomal subunit with A-site tRNA, P-site tRNA and eIF-5AELECTRON MICROSCOPY3.882016-02-24
1387OF1|1|35S rRNASaccharomyces cerevisiae S288CNog1-TAP associated immature ribosomal particle population A from S. cerevisiaeELECTRON MICROSCOPY3.12021-11-03

Release history

Release3.2303.231
Date2022-05-112022-05-18

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. Instances are ordered to put similar structures near each other. The colorbar ranges from 0 to the maximum observed discrepancy, up to 0.5

#S - ordering by similarity (same as in the heat map).
#SPDBTitleMethodResolutionLength
17OF1|1|3Nog1-TAP associated immature ribosomal particle population A from S. cerevisiaeELECTRON MICROSCOPY3.143
26N8J|1|2Cryo-EM structure of late nuclear (LN) pre-60S ribosomal subunitELECTRON MICROSCOPY3.5121
35H4P|1|3Structural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1, Tif6 and Reh1ELECTRON MICROSCOPY3.07121
46GQV|1|3Cryo-EM recosntruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP)ELECTRON MICROSCOPY4121
56GQB|1|3Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GDP+AlF4/sordarin)ELECTRON MICROSCOPY3.9121
66N8O|1|BCryo-EM structure of Rpl10-inserted (RI) pre-60S ribosomal subunitELECTRON MICROSCOPY3.5121
76N8M|1|BCryo-EM structure of pre-Lsg1 (PL) pre-60S ribosomal subunitELECTRON MICROSCOPY3.5121
86N8N|1|BCryo-EM structure of Lsg1-engaged (LE) pre-60S ribosomal subunitELECTRON MICROSCOPY3.8121
96N8L|1|2Cryo-EM structure of early cytoplasmic-late (ECL) pre-60S ribosomal subunitELECTRON MICROSCOPY3.6121
106N8K|1|2Cryo-EM structure of early cytoplasmic-immediate (ECI) pre-60S ribosomal subunitELECTRON MICROSCOPY3.6121
115T62|1|BNmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis: 60S-Nmd3-Tif6-Lsg1 ComplexELECTRON MICROSCOPY3.1121
126S05|1|xCryo-EM structures of Lsg1-TAP pre-60S ribosomal particlesELECTRON MICROSCOPY3.9121
136QIK|1|xCryo-EM structures of Lsg1-TAP pre-60S ribosomal particlesELECTRON MICROSCOPY3.1121
146RZZ|1|xCryo-EM structures of Lsg1-TAP pre-60S ribosomal particlesELECTRON MICROSCOPY3.2121
155OBM|1|3Crystal structure of Gentamicin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.4121
165OBM|1|7Crystal structure of Gentamicin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.4121
176QT0|1|xCryo-EM structures of Lsg1-TAP pre-60S ribosomal particlesELECTRON MICROSCOPY3.4121
185M1J|1|34Nonstop ribosomal complex bound with Dom34 and Hbs1ELECTRON MICROSCOPY3.3121
196XIR|1|3Cryo-EM Structure of K63 Ubiquitinated Yeast Translocating Ribosome under Oxidative StressELECTRON MICROSCOPY3.2121
206QTZ|1|xCryo-EM structures of Lsg1-TAP pre-60S ribosomal particlesELECTRON MICROSCOPY3.5121
216RI5|1|xCryo-EM structures of Lsg1-TAP pre-60S ribosomal particlesELECTRON MICROSCOPY3.3121
227RR5|1|C4Structure of ribosomal complex bound with Rbg1/Tma46ELECTRON MICROSCOPY3.23121
237NRC|1|LBStructure of the yeast Gcn1 bound to a leading stalled 80S ribosome with Rbg2, Gir2, A- and P-tRNA and eIF5AELECTRON MICROSCOPY3.9121
246TNU|1|BRYeast 80S ribosome in complex with eIF5A and decoding A-site and P-site tRNAs.ELECTRON MICROSCOPY3.1121
257B7D|1|LBYeast 80S ribosome bound to eEF3 and A/A- and P/P-tRNAsELECTRON MICROSCOPY3.3121
265MC6|1|BRCryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiaeELECTRON MICROSCOPY3.8121
275APN|1|7Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and N-terminally tagged Rei1ELECTRON MICROSCOPY3.91121
285APO|1|7Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and C-terminally tagged Rei1ELECTRON MICROSCOPY3.41121
295TGM|1|3Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-ProX-RAY DIFFRACTION3.5121
305DGF|1|3Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analogX-RAY DIFFRACTION3.3121
315DGE|1|3Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosomeX-RAY DIFFRACTION3.45121
325DC3|1|3Complex of yeast 80S ribosome with non-modified eIF5AX-RAY DIFFRACTION3.25121
335DGV|1|3Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analogX-RAY DIFFRACTION3.1121
345LYB|1|3Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCPmnX-RAY DIFFRACTION3.25121
355TGA|1|3Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-ProX-RAY DIFFRACTION3.3121
365I4L|1|3Crystal structure of Amicoumacin A bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.1121
374U53|1|3Crystal structure of Deoxynivalenol bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.3121
384U50|1|3Crystal structure of Verrucarin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.2121
394U6F|1|3Crystal structure of T-2 toxin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.1121
404U3N|1|3Crystal structure of CCA trinucleotide bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.2121
414U4Y|1|3Crystal structure of Pactamycin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.2121
424U51|1|3Crystal structure of Narciclasine bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.2121
434U55|1|3Crystal structure of Cryptopleurine bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.2121
444U4N|1|3Crystal structure of Edeine bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.1121
454U4Z|1|3Crystal structure of Phyllanthoside bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.1121
464U4R|1|3Crystal structure of Lactimidomycin bound to the yeast 80S ribosomeX-RAY DIFFRACTION2.8121
474V88|1|A3The structure of the eukaryotic ribosome at 3.0 A resolution.X-RAY DIFFRACTION3121
484U3U|1|3Crystal structure of Cycloheximide bound to the yeast 80S ribosomeX-RAY DIFFRACTION2.9121
494U3M|1|3Crystal structure of Anisomycin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3121
504U4U|1|3Crystal structure of Lycorine bound to the yeast 80S ribosomeX-RAY DIFFRACTION3121
514U4Q|1|3Crystal structure of Homoharringtonine bound to the yeast 80S ribosomeX-RAY DIFFRACTION3121
526HHQ|1|3Crystal structure of compound C45 bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.1121
535TBW|1|3Crystal structure of chlorolissoclimide bound to the yeast 80S ribosomeX-RAY DIFFRACTION3121
545ON6|1|3Crystal structure of haemanthamine bound to the 80S ribosomeX-RAY DIFFRACTION3.1121
554U52|1|3Crystal structure of Nagilactone C bound to the yeast 80S ribosomeX-RAY DIFFRACTION3121
564U56|1|3Crystal structure of Blasticidin S bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.45121
575DAT|1|3Complex of yeast 80S ribosome with hypusine-containing eIF5AX-RAY DIFFRACTION3.15121
585MEI|1|3Crystal structure of Agelastatin A bound to the 80S ribosomeX-RAY DIFFRACTION3.5121
595NDG|1|3Crystal structure of geneticin (G418) bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.7121
605NDW|1|3Crystal structure of aminoglycoside TC007 bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.7121
614U4O|1|3Crystal structure of Geneticin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.6121
625NDV|1|3Crystal structure of Paromomycin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.3121
635NDV|1|7Crystal structure of Paromomycin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.3121
645TBW|1|ASCrystal structure of chlorolissoclimide bound to the yeast 80S ribosomeX-RAY DIFFRACTION3121
656HHQ|1|ASCrystal structure of compound C45 bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.1121
665ON6|1|ASCrystal structure of haemanthamine bound to the 80S ribosomeX-RAY DIFFRACTION3.1121
675MEI|1|ASCrystal structure of Agelastatin A bound to the 80S ribosomeX-RAY DIFFRACTION3.5121
684U4O|1|7Crystal structure of Geneticin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.6121
695TGM|1|7Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-ProX-RAY DIFFRACTION3.5121
705DGE|1|7Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosomeX-RAY DIFFRACTION3.45121
715DC3|1|7Complex of yeast 80S ribosome with non-modified eIF5AX-RAY DIFFRACTION3.25121
725DGV|1|7Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analogX-RAY DIFFRACTION3.1121
734U6F|1|7Crystal structure of T-2 toxin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.1121
745DGF|1|7Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analogX-RAY DIFFRACTION3.3121
755DAT|1|7Complex of yeast 80S ribosome with hypusine-containing eIF5AX-RAY DIFFRACTION3.15121
764U52|1|7Crystal structure of Nagilactone C bound to the yeast 80S ribosomeX-RAY DIFFRACTION3121
774U50|1|7Crystal structure of Verrucarin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.2121
784U51|1|7Crystal structure of Narciclasine bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.2121
794U53|1|7Crystal structure of Deoxynivalenol bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.3121
804U4U|1|7Crystal structure of Lycorine bound to the yeast 80S ribosomeX-RAY DIFFRACTION3121
814U4Q|1|7Crystal structure of Homoharringtonine bound to the yeast 80S ribosomeX-RAY DIFFRACTION3121
824U4N|1|7Crystal structure of Edeine bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.1121
834U4Z|1|7Crystal structure of Phyllanthoside bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.1121
844U3N|1|7Crystal structure of CCA trinucleotide bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.2121
854U55|1|7Crystal structure of Cryptopleurine bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.2121
864U4Y|1|7Crystal structure of Pactamycin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.2121
874U3M|1|7Crystal structure of Anisomycin bound to the yeast 80S ribosomeX-RAY DIFFRACTION3121
884U4R|1|7Crystal structure of Lactimidomycin bound to the yeast 80S ribosomeX-RAY DIFFRACTION2.8121
894U3U|1|7Crystal structure of Cycloheximide bound to the yeast 80S ribosomeX-RAY DIFFRACTION2.9121
904V88|1|A7The structure of the eukaryotic ribosome at 3.0 A resolution.X-RAY DIFFRACTION3121
915I4L|1|7Crystal structure of Amicoumacin A bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.1121
925LYB|1|7Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCPmnX-RAY DIFFRACTION3.25121
935TGA|1|7Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-ProX-RAY DIFFRACTION3.3121
944U56|1|7Crystal structure of Blasticidin S bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.45121
955NDG|1|7Crystal structure of geneticin (G418) bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.7121
965NDW|1|7Crystal structure of aminoglycoside TC007 bound to the yeast 80S ribosomeX-RAY DIFFRACTION3.7121
976WOO|1|7CryoEM structure of yeast 80S ribosome with Met-tRNAiMet, eIF5B, and GDPELECTRON MICROSCOPY2.9121
987MPI|1|A3Stm1 bound vacant 80S structure isolated from cbf5-D95AELECTRON MICROSCOPY3.05121
997N8B|1|A3Cycloheximide bound vacant 80S structure isolated from cbf5-D95AELECTRON MICROSCOPY3.05121
1007MPJ|1|A3Stm1 bound vacant 80S structure isolated from nop1-D243AELECTRON MICROSCOPY2.7120
1017AZY|1|FContext-specific inhibition of eukaryotic translation by macrolide antibioticsELECTRON MICROSCOPY2.877121
1026Q8Y|1|BRCryo-EM structure of the mRNA translating and degrading yeast 80S ribosome-Xrn1 nuclease complexELECTRON MICROSCOPY3.1121
1036Z6J|1|C4Cryo-EM structure of yeast Lso2 bound to 80S ribosomes under native conditionELECTRON MICROSCOPY3.4121
1046Z6K|1|C4Cryo-EM structure of yeast reconstituted Lso2 bound to 80S ribosomesELECTRON MICROSCOPY3.4121
1056S47|1|ABSaccharomyces cerevisiae 80S ribosome bound with ABCF protein New1ELECTRON MICROSCOPY3.28121
1066TB3|1|BRyeast 80S ribosome in complex with the Not5 subunit of the CCR4-NOT complexELECTRON MICROSCOPY2.8121
1076T4Q|1|C4Structure of yeast 80S ribosome stalled on the CGA-CCG inhibitory codon combination.ELECTRON MICROSCOPY2.6121
1086SNT|1|4Yeast 80S ribosome stalled on SDD1 mRNA.ELECTRON MICROSCOPY2.8121
1096T7T|1|C4Structure of yeast 80S ribosome stalled on poly(A) tract.ELECTRON MICROSCOPY3.1121
1106T7I|1|C4Structure of yeast 80S ribosome stalled on the CGA-CGA inhibitory codon combination.ELECTRON MICROSCOPY3.2121
1116T83|1|4bStructure of yeast disome (di-ribosome) stalled on poly(A) tract.ELECTRON MICROSCOPY4121
1126T83|1|BbStructure of yeast disome (di-ribosome) stalled on poly(A) tract.ELECTRON MICROSCOPY4121
1136SV4|1|BRThe cryo-EM structure of SDD1-stalled collided trisome.ELECTRON MICROSCOPY3.3121
1146SV4|1|ZRThe cryo-EM structure of SDD1-stalled collided trisome.ELECTRON MICROSCOPY3.3121
1156SV4|1|YRThe cryo-EM structure of SDD1-stalled collided trisome.ELECTRON MICROSCOPY3.3121
1166R87|1|3Yeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state without Arb1)ELECTRON MICROSCOPY3.4121
1176R84|1|3Yeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state with Arb1)ELECTRON MICROSCOPY3.6121
1186R86|1|3Yeast Vms1-60S ribosomal subunit complex (post-state)ELECTRON MICROSCOPY3.4121
1197OSA|1|ABPre-translocation complex of 80 S.cerevisiae ribosome with eEF2 and ligandsX-RAY DIFFRACTION3121
1207OSM|1|ABIntermediate translocation complex of 80 S.cerevisiae ribosome with eEF2 and ligandsX-RAY DIFFRACTION3121
1215JUP|1|DSaccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure II (mid-rotated 40S subunit)ELECTRON MICROSCOPY3.5121
1225JUU|1|DSaccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure V (least rotated 40S subunit)ELECTRON MICROSCOPY4121
1235JUT|1|DSaccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure IV (almost non-rotated 40S subunit)ELECTRON MICROSCOPY4121
1245JUO|1|DSaccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure I (fully rotated 40S subunit)ELECTRON MICROSCOPY4121
1255GAK|1|3Yeast 60S ribosomal subunit with A-site tRNA, P-site tRNA and eIF-5AELECTRON MICROSCOPY3.88121
1266HD7|1|3Cryo-EM structure of the ribosome-NatA complexELECTRON MICROSCOPY3.4121
1273JCT|1|3Cryo-em structure of eukaryotic pre-60S ribosomal subunitsELECTRON MICROSCOPY3.08121
1287BTB|1|3Cryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.22 Angstroms resolution(state R2)ELECTRON MICROSCOPY3.22121
1296FT6|1|3Structure of the Nop53 pre-60S particle bound to the exosome nuclear cofactorsELECTRON MICROSCOPY3.9121
1306OIG|1|7Subunit joining exposes nascent pre-40S rRNA for processing and quality controlELECTRON MICROSCOPY3.8121
1316YLG|1|3Rix1-Rea1 pre-60S particle - 60S core, body 1 (rigid body refinement)ELECTRON MICROSCOPY3117
1326YLH|1|3Rix1-Rea1 pre-60S particle - full composite structureELECTRON MICROSCOPY3.1117
1337BT6|1|3Cryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.12 Angstroms resolution(state R1)ELECTRON MICROSCOPY3.12121
1347OH3|1|3Nog1-TAP associated immature ribosomal particle population B from S. cerevisiaeELECTRON MICROSCOPY3.4121
1357OHQ|1|3Nog1-TAP associated immature ribosomal particle population C from S. cerevisiaeELECTRON MICROSCOPY3.1121
1366M62|1|3Cryo-Em structure of eukaryotic pre-60S ribosome subunit from Saccharomyces cerevisiae rpf2 delta 255-344 strain, C4 state.ELECTRON MICROSCOPY3.2121
1374V7R|1|B2Yeast 80S ribosome.X-RAY DIFFRACTION4121
1384V7R|1|D2Yeast 80S ribosome.X-RAY DIFFRACTION4121