NR_4.0_46995.12

Members (36)
History
Heat map

#	IFE	Standardized name	Molecule	Organism	Source	Rfam	Title	Method	Res. Å	Date
1	6ZM7\|1\|S2 (rep)	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex	Electron microscopy	2.7	2020-07-29
2	6ZLW\|1\|2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	SARS-CoV-2 Nsp1 bound to the human 40S ribosomal subunit	Electron microscopy	2.6	2020-07-29
3	6Z6N\|1\|S2	Small subunit ribosomal RNA	18S rRNA	Homo sapiens	Eukarya	RF01960	Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)	Electron microscopy	2.9	2020-07-29
4	6ZOJ\|1\|2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	SARS-CoV-2-Nsp1-40S complex, composite map	Electron microscopy	2.8	2020-07-22
5	6ZP4\|1\|2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2	Electron microscopy	2.9	2020-07-29
6	6QZP\|1\|S2	Small subunit ribosomal RNA	18S rRNA (1740-MER)	Homo sapiens	Eukarya	RF01960	High-resolution cryo-EM structure of the human 80S ribosome	Electron microscopy	2.9	2019-04-24
7	6ZME\|1\|S2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex	Electron microscopy	3	2020-08-12
8	6Z6L\|1\|S2	Small subunit ribosomal RNA	18S rRNA	Homo sapiens	Eukarya	RF01960	Cryo-EM structure of human CCDC124 bound to 80S ribosomes	Electron microscopy	3	2020-07-29
9	6EK0\|1\|S2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	High-resolution cryo-EM structure of the human 80S ribosome	Electron microscopy	2.9	2018-01-24
10	6ZON\|1\|2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 1	Electron microscopy	3	2020-07-29
11	6Z6M\|1\|S2	Small subunit ribosomal RNA	18S rRNA	Homo sapiens	Eukarya	RF01960	Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1	Electron microscopy	3.1	2020-07-29
12	6Y2L\|1\|S2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Structure of human ribosome in POST state	Electron microscopy	3	2020-04-15
13	6OM0\|1\|S2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs	Electron microscopy	3.1	2019-06-19
14	6OLE\|1\|S2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs	Electron microscopy	3.1	2019-06-19
15	6ZN5\|1\|2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex - state 2	Electron microscopy	3.2	2020-07-29
16	6Y0G\|1\|S2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Structure of human ribosome in classical-PRE state	Electron microscopy	3.2	2020-04-15
17	6OLG\|1\|B1	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)	Electron microscopy	3.4	2019-06-19
18	6OLI\|1\|S2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)	Electron microscopy	3.5	2019-06-19
19	6Y57\|1\|S2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Structure of human ribosome in hybrid-PRE state	Electron microscopy	3.5	2020-04-15
20	6G18\|1\|2	Small subunit ribosomal RNA	pre-18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Cryo-EM structure of a late human pre-40S ribosomal subunit - State C	Electron microscopy	3.6	2018-06-06
21	6G5I\|1\|2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Cryo-EM structure of a late human pre-40S ribosomal subunit - State R	Electron microscopy	3.5	2018-06-06
22	4UG0\|1\|S2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	STRUCTURE OF THE HUMAN 80S RIBOSOME	Electron microscopy	3.6	2015-06-10
23	6IP8\|1\|2m	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)	Electron microscopy	3.9	2019-05-29
24	6IP5\|1\|2m	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)	Electron microscopy	3.9	2019-05-29
25	6G5H\|1\|2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Cryo-EM structure of a late human pre-40S ribosomal subunit - Mature	Electron microscopy	3.6	2018-06-06
26	6ZOK\|1\|2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	SARS-CoV-2-Nsp1-40S complex, focused on body	Electron microscopy	2.8	2020-07-29
27	6OM7\|1\|S2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs	Electron microscopy	3.7	2019-06-19
28	6OLZ\|1\|B1	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA	Electron microscopy	3.9	2019-06-19
29	5AJ0\|1\|B1	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Cryo electron microscopy of actively translating human polysomes (POST state).	Electron microscopy	3.5	2015-05-20
30	6OLF\|1\|S2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs	Electron microscopy	3.9	2019-06-19
31	5A2Q\|1\|2	Small subunit ribosomal RNA	18S RRNA	Homo sapiens	Eukarya	RF01960	Structure of the HCV IRES bound to the human ribosome	Electron microscopy	3.9	2015-07-15
32	6G4S\|1\|2	Small subunit ribosomal RNA	pre-18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Cryo-EM structure of a late human pre-40S ribosomal subunit - State B	Electron microscopy	4	2018-06-06
33	5LKS\|1\|S2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	Structure-function insights reveal the human ribosome as a cancer target for antibiotics	Electron microscopy	3.6	2017-04-26
34	6ZOL\|1\|2	Small subunit ribosomal RNA	18S ribosomal RNA	Homo sapiens	Eukarya	RF01960	SARS-CoV-2-Nsp1-40S complex, focused on head	Electron microscopy	2.8	2020-07-22
35	5T2C\|1\|AA	Small subunit ribosomal RNA	18S rRNA	Homo sapiens	Eukarya	RF01960	CryoEM structure of the human ribosome at 3.6 Angstrom resolution	Electron microscopy	3.6	2017-01-25
36	5A8L\|1\|B	Small subunit ribosomal RNA	HUMAN 18S RIBOSOMAL RNA	Homo sapiens	Eukarya	RF01960	Human eRF1 and the hCMV nascent peptide in the translation termination complex	Electron microscopy	3.8	2015-12-02

Release history

Release	3.139
Date	2020-08-12

Parents

This class	Parent classes	Release id	Intersection	Added to this class	Only in parent
NR_4.0_46995.12	NR_4.0_46995.11	3.139	(35) 6QZP\|1\|S2, 6OM7\|1\|S2, 6OM0\|1\|S2, 6OLZ\|1\|B1, 6OLI\|1\|S2, 6OLG\|1\|B1, 6OLF\|1\|S2, 6OLE\|1\|S2, 6IP8\|1\|2m, 6IP5\|1\|2m, 6G5I\|1\|2, 6G5H\|1\|2, 6G4S\|1\|2, 6G18\|1\|2, 6EK0\|1\|S2, 5T2C\|1\|AA, 5LKS\|1\|S2, 5AJ0\|1\|B1, 5A8L\|1\|B, 6ZP4\|1\|2, 5A2Q\|1\|2, 6ZON\|1\|2, 4UG0\|1\|S2, 6ZOL\|1\|2, 6ZOK\|1\|2, 6ZOJ\|1\|2, 6ZN5\|1\|2, 6ZM7\|1\|S2, 6ZLW\|1\|2, 6Z6N\|1\|S2, 6Z6M\|1\|S2, 6Z6L\|1\|S2, 6Y57\|1\|S2, 6Y2L\|1\|S2, 6Y0G\|1\|S2	(1) 6ZME\|1\|S2	(0)

Children

This class	Descendant classes	Release id	Intersection	Only in this class	Added to child
NR_4.0_46995.12	NR_4.0_46995.13	3.140	(36) 6IP8\|1\|2m, 6ZON\|1\|2, 5A8L\|1\|B, 6Z6L\|1\|S2, 6OLF\|1\|S2, 5LKS\|1\|S2, 6Z6N\|1\|S2, 6OLI\|1\|S2, 6EK0\|1\|S2, 6ZM7\|1\|S2, 6OM0\|1\|S2, 6G4S\|1\|2, 6ZN5\|1\|2, 6QZP\|1\|S2, 6G5I\|1\|2, 6ZOK\|1\|2, 4UG0\|1\|S2, 6Y2L\|1\|S2, 5A2Q\|1\|2, 6OLE\|1\|S2, 5AJ0\|1\|B1, 6OLG\|1\|B1, 5T2C\|1\|AA, 6OLZ\|1\|B1, 6G18\|1\|2, 6OM7\|1\|S2, 6G5H\|1\|2, 6IP5\|1\|2m, 6Y57\|1\|S2, 6ZP4\|1\|2, 6Z6M\|1\|S2, 6ZLW\|1\|2, 6ZME\|1\|S2, 6ZOJ\|1\|2, 6Y0G\|1\|S2, 6ZOL\|1\|2	(0)	(8) 6ZMT\|1\|2, 6ZVH\|1\|2, 6ZMO\|1\|S2, 6ZMI\|1\|S2, 3J74\|1\|S2, 3J73\|1\|S2, 1VX5\|1\|2, 1VX2\|1\|2

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. Instances are ordered to put similar structures near each other. The colorbar ranges from 0 to the maximum observed discrepancy, up to 0.5

#S - ordering by similarity (same as in the heat map).

#S	PDB	Title	Method	Resolution	Length
1	5A8L\|1\|B	Human eRF1 and the hCMV nascent peptide in the translation termination complex	ELECTRON MICROSCOPY	3.8	67
2	6IP8\|1\|2m	Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)	ELECTRON MICROSCOPY	3.9	1742
3	6IP5\|1\|2m	Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)	ELECTRON MICROSCOPY	3.9	1742
4	5LKS\|1\|S2	Structure-function insights reveal the human ribosome as a cancer target for antibiotics	ELECTRON MICROSCOPY	3.6	1742
5	4UG0\|1\|S2	STRUCTURE OF THE HUMAN 80S RIBOSOME	ELECTRON MICROSCOPY	3.6	1742
6	5T2C\|1\|AA	CryoEM structure of the human ribosome at 3.6 Angstrom resolution	ELECTRON MICROSCOPY	3.6	1742
7	6OLZ\|1\|B1	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA	ELECTRON MICROSCOPY	3.9	1708
8	6OLG\|1\|B1	Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)	ELECTRON MICROSCOPY	3.4	1708
9	5AJ0\|1\|B1	Cryo electron microscopy of actively translating human polysomes (POST state).	ELECTRON MICROSCOPY	3.5	1708
10	6Y2L\|1\|S2	Structure of human ribosome in POST state	ELECTRON MICROSCOPY	3	1713
11	6Y57\|1\|S2	Structure of human ribosome in hybrid-PRE state	ELECTRON MICROSCOPY	3.5	1658
12	6Y0G\|1\|S2	Structure of human ribosome in classical-PRE state	ELECTRON MICROSCOPY	3.2	1697
13	6OLF\|1\|S2	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs	ELECTRON MICROSCOPY	3.9	1680
14	6OLE\|1\|S2	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs	ELECTRON MICROSCOPY	3.1	1680
15	6OLI\|1\|S2	Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)	ELECTRON MICROSCOPY	3.5	1680
16	6QZP\|1\|S2	High-resolution cryo-EM structure of the human 80S ribosome	ELECTRON MICROSCOPY	2.9	1707
17	6EK0\|1\|S2	High-resolution cryo-EM structure of the human 80S ribosome	ELECTRON MICROSCOPY	2.9	1706
18	6Z6L\|1\|S2	Cryo-EM structure of human CCDC124 bound to 80S ribosomes	ELECTRON MICROSCOPY	3	1740
19	6Z6N\|1\|S2	Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)	ELECTRON MICROSCOPY	2.9	1740
20	6ZM7\|1\|S2	SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex	ELECTRON MICROSCOPY	2.7	1740
21	6ZME\|1\|S2	SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex	ELECTRON MICROSCOPY	3	1740
22	6ZN5\|1\|2	SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex - state 2	ELECTRON MICROSCOPY	3.2	1671
23	6ZLW\|1\|2	SARS-CoV-2 Nsp1 bound to the human 40S ribosomal subunit	ELECTRON MICROSCOPY	2.6	1665
24	6ZOL\|1\|2	SARS-CoV-2-Nsp1-40S complex, focused on head	ELECTRON MICROSCOPY	2.8	472
25	6ZP4\|1\|2	SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2	ELECTRON MICROSCOPY	2.9	1721
26	6ZOK\|1\|2	SARS-CoV-2-Nsp1-40S complex, focused on body	ELECTRON MICROSCOPY	2.8	1232
27	6ZOJ\|1\|2	SARS-CoV-2-Nsp1-40S complex, composite map	ELECTRON MICROSCOPY	2.8	1704
28	6ZON\|1\|2	SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 1	ELECTRON MICROSCOPY	3	1721
29	5A2Q\|1\|2	Structure of the HCV IRES bound to the human ribosome	ELECTRON MICROSCOPY	3.9	1665
30	6Z6M\|1\|S2	Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1	ELECTRON MICROSCOPY	3.1	1740
31	6G5H\|1\|2	Cryo-EM structure of a late human pre-40S ribosomal subunit - Mature	ELECTRON MICROSCOPY	3.6	1665
32	6G5I\|1\|2	Cryo-EM structure of a late human pre-40S ribosomal subunit - State R	ELECTRON MICROSCOPY	3.5	1657
33	6G18\|1\|2	Cryo-EM structure of a late human pre-40S ribosomal subunit - State C	ELECTRON MICROSCOPY	3.6	1658
34	6OM7\|1\|S2	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs	ELECTRON MICROSCOPY	3.7	1680
35	6OM0\|1\|S2	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs	ELECTRON MICROSCOPY	3.1	1680
36	6G4S\|1\|2	Cryo-EM structure of a late human pre-40S ribosomal subunit - State B	ELECTRON MICROSCOPY	4	1613

Equivalence class NR_4.0_46995.12 Obsolete

Release history

Parents

Children