NR_4.0_65061.23

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#	IFE	Standardized name	Molecule	Organism	Source	Rfam	Title	Method	Res. Å	Date
1	8GLP\|1\|L5+ 8GLP\|1\|L8 (rep)	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)	Electron microscopy	1.67	2023-04-19
2	8A3D\|1\|A+ 8A3D\|1\|C	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human mature large subunit of the ribosome with eIF6 and homoharringtonine bound	Electron microscopy	1.67	2023-03-08
3	8G5Y\|1\|L5+ 8G5Y\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)	Electron microscopy	2.29	2023-04-19
4	8JDK\|1\|D	Large subunit ribosomal RNA	28S ribosomal RNA	Homo sapiens	Eukarya	RF02543	Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)	Electron microscopy	2.26	2023-12-06
5	7XNY\|1\|L1+ 7XNY\|1\|L3	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells	Electron microscopy	2.5	2023-04-05
6	6ZMI\|1\|L5+ 6ZMI\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex	Electron microscopy	2.6	2020-08-19
7	7OW7\|1\|A+ 7OW7\|1\|C	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	EIF6-bound large subunit of the human ribosome	Electron microscopy	2.2	2022-10-05
8	8JDL\|1\|D	Large subunit ribosomal RNA	28S ribosomal RNA	Homo sapiens	Eukarya	RF02543	Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state)	Electron microscopy	2.42	2023-12-06
9	6ZM7\|1\|L5+ 6ZM7\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex	Electron microscopy	2.7	2020-07-29
10	8G60\|1\|L5+ 8G60\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)	Electron microscopy	2.54	2023-04-19
11	7XNX\|1\|L1+ 7XNX\|1\|L3	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells	Electron microscopy	2.7	2023-04-05
12	8JDJ\|1\|D	Large subunit ribosomal RNA	28S ribosomal RNA	Homo sapiens	Eukarya	RF02543	Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU)	Electron microscopy	2.5	2023-12-06
13	8G5Z\|1\|L5+ 8G5Z\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)	Electron microscopy	2.64	2023-04-19
14	7F5S\|1\|L5+ 7F5S\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	human delta-METTL18 60S ribosome	Electron microscopy	2.72	2022-06-22
15	8FL3\|1\|L3+ 8FL3\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nuclear pre-60S ribosomal subunit (State I2)	Electron microscopy	2.53	2023-07-12
16	6Y6X\|1\|L5+ 6Y6X\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Tetracenomycin X bound to the human ribosome	Electron microscopy	2.8	2020-07-08
17	6Z6N\|1\|L5+ 6Z6N\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)	Electron microscopy	2.9	2020-07-29
18	8FLE\|1\|L3+ 8FLE\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nuclear pre-60S ribosomal subunit (State L2)	Electron microscopy	2.48	2023-07-12
19	8FLB\|1\|L3+ 8FLB\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nuclear pre-60S ribosomal subunit (State K2)	Electron microscopy	2.55	2023-07-12
20	8JDM\|1\|D	Large subunit ribosomal RNA	28S ribosomal RNA	Homo sapiens	Eukarya	RF02543	Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (rotated state)	Electron microscopy	2.67	2023-12-06
21	8FL7\|1\|L3+ 8FL7\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nuclear pre-60S ribosomal subunit (State J2)	Electron microscopy	2.55	2023-07-12
22	8G6J\|1\|L5+ 8G6J\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)	Electron microscopy	2.8	2023-04-19
23	6QZP\|1\|L5+ 6QZP\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA (3773-MER), 5.8S rRNA (156-MER)	Homo sapiens	Eukarya	RF02543 + RF00002	High-resolution cryo-EM structure of the human 80S ribosome	Electron microscopy	2.9	2019-04-24
24	6ZME\|1\|L5+ 6ZME\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex	Electron microscopy	3	2020-08-12
25	6Z6L\|1\|L5+ 6Z6L\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Cryo-EM structure of human CCDC124 bound to 80S ribosomes	Electron microscopy	3	2020-07-29
26	7QVP\|1\|L5+ 7QVP\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human collided disome (di-ribosome) stalled on XBP1 mRNA	Electron microscopy	3	2022-10-12
27	8FLD\|1\|L3+ 8FLD\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nuclear pre-60S ribosomal subunit (State L1)	Electron microscopy	2.58	2023-07-12
28	8FL6\|1\|L3+ 8FL6\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nuclear pre-60S ribosomal subunit (State J1)	Electron microscopy	2.62	2023-07-12
29	8FLA\|1\|L3+ 8FLA\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nuclear pre-60S ribosomal subunit (State K1)	Electron microscopy	2.63	2023-07-12
30	8FL2\|1\|L3+ 8FL2\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nuclear pre-60S ribosomal subunit (State I1)	Electron microscopy	2.67	2023-07-12
31	7QVP\|1\|L6+ 7QVP\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human collided disome (di-ribosome) stalled on XBP1 mRNA	Electron microscopy	3	2022-10-12
32	8IDT\|1\|2+ 8IDT\|1\|8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	human nuclear pre-60S ribosomal particle - State G	Electron microscopy	2.8	2023-08-09
33	6XA1\|1\|L5+ 6XA1\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Structure of a drug-like compound stalled human translation termination complex	Electron microscopy	2.8	2020-10-07
34	6ZMO\|1\|L5+ 6ZMO\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex	Electron microscopy	3.1	2020-08-19
35	6Z6M\|1\|L5+ 6Z6M\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1	Electron microscopy	3.1	2020-07-29
36	8FLF\|1\|L3+ 8FLF\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nuclear pre-60S ribosomal subunit (State L3)	Electron microscopy	2.65	2023-07-12
37	8G61\|1\|L5+ 8G61\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)	Electron microscopy	2.94	2023-04-19
38	8INF\|1\|2+ 8INF\|1\|8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	human nuclear pre-60S ribosomal particle - State F'	Electron microscopy	3	2023-08-09
39	8IDY\|1\|2+ 8IDY\|1\|8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	human nuclear pre-60S ribosomal particle - State F	Electron microscopy	3	2023-08-09
40	8FL9\|1\|L3+ 8FL9\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nuclear pre-60S ribosomal subunit (State J3)	Electron microscopy	2.75	2023-07-12
41	8FLC\|1\|L3+ 8FLC\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nuclear pre-60S ribosomal subunit (State K3)	Electron microscopy	2.76	2023-07-12
42	6OLE\|1\|t+ 6OLE\|1\|D	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs	Electron microscopy	3.1	2019-06-19
43	6OM0\|1\|t+ 6OM0\|1\|D	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs	Electron microscopy	3.1	2019-06-19
44	6Y2L\|1\|L5+ 6Y2L\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Structure of human ribosome in POST state	Electron microscopy	3	2020-04-15
45	8FL4\|1\|L3+ 8FL4\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nuclear pre-60S ribosomal subunit (State I3)	Electron microscopy	2.89	2023-07-12
46	6LQM\|1\|2+ 6LQM\|1\|8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Cryo-EM structure of a pre-60S ribosomal subunit - state C	Electron microscopy	3.09	2020-08-26
47	6Y0G\|1\|L5+ 6Y0G\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Structure of human ribosome in classical-PRE state	Electron microscopy	3.2	2020-04-15
48	7BHP\|1\|L5+ 7BHP\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Cryo-EM structure of the human Ebp1 - 80S ribosome	Electron microscopy	3.3	2021-02-03
49	6LU8\|1\|2+ 6LU8\|1\|8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Cryo-EM structure of a human pre-60S ribosomal subunit - state A	Electron microscopy	3.13	2020-08-26
50	6LSR\|1\|2+ 6LSR\|1\|8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Cryo-EM structure of a pre-60S ribosomal subunit - state B	Electron microscopy	3.13	2020-08-26
51	8INE\|1\|2+ 8INE\|1\|8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	human nuclear pre-60S ribosomal particle - State G'	Electron microscopy	3.2	2023-08-09
52	8INK\|1\|2+ 8INK\|1\|8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	human nuclear pre-60S ribosomal particle - State D	Electron microscopy	3.2	2023-08-09
53	8IPY\|1\|2+ 8IPY\|1\|8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	human nuclear pre-60S ribosomal particle - State D'	Electron microscopy	3.2	2023-08-09
54	8IPD\|1\|2+ 8IPD\|1\|8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	human nuclear pre-60S ribosomal particle - State C	Electron microscopy	3.2	2023-08-09
55	6LSS\|1\|2+ 6LSS\|1\|8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Cryo-EM structure of a pre-60S ribosomal subunit - state preA	Electron microscopy	3.23	2020-08-26
56	8IE3\|1\|2+ 8IE3\|1\|8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	human nuclear pre-60S ribosomal particle - State E	Electron microscopy	3.3	2023-08-09
57	8FKY\|1\|L3+ 8FKY\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nucleolar pre-60S ribosomal subunit (State F)	Electron microscopy	2.67	2023-07-12
58	6OLI\|1\|t+ 6OLI\|1\|D	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)	Electron microscopy	3.5	2019-06-19
59	6OLG\|1\|A2+ 6OLG\|1\|A3	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)	Electron microscopy	3.4	2019-06-19
60	8FKW\|1\|L3+ 8FKW\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nucleolar pre-60S ribosomal subunit (State D2)	Electron microscopy	2.5	2023-07-12
61	8IR1\|1\|2+ 8IR1\|1\|8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRMA	Homo sapiens	Eukarya	RF02543 + RF00002	human nuclear pre-60S ribosomal particle - State A	Electron microscopy	3.3	2023-08-09
62	8FKV\|1\|L3+ 8FKV\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nucleolar pre-60S ribosomal subunit (State D1)	Electron microscopy	2.47	2023-07-12
63	8IR3\|1\|2+ 8IR3\|1\|8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	human nuclear pre-60S ribosomal particle - State B'	Electron microscopy	3.5	2023-08-09
64	6Y57\|1\|L5+ 6Y57\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Structure of human ribosome in hybrid-PRE state	Electron microscopy	3.5	2020-04-15
65	8FKX\|1\|L3+ 8FKX\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nucleolar pre-60S ribosomal subunit (State E)	Electron microscopy	2.59	2023-07-12
66	5T2C\|1\|A+ 5T2C\|1\|C	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	CryoEM structure of the human ribosome at 3.6 Angstrom resolution	Electron microscopy	3.6	2017-01-25
67	8FKZ\|1\|L3+ 8FKZ\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nucleolar pre-60S ribosomal subunit (State G)	Electron microscopy	3.04	2023-07-12
68	6OM7\|1\|t+ 6OM7\|1\|D	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs	Electron microscopy	3.7	2019-06-19
69	4UG0\|1\|L5+ 4UG0\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	STRUCTURE OF THE HUMAN 80S RIBOSOME	Electron microscopy	3.6	2015-06-10
70	6OLF\|1\|t+ 6OLF\|1\|D	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs	Electron microscopy	3.9	2019-06-19
71	6W6L\|1\|t+ 6W6L\|1\|D	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Cryo-EM structure of the human ribosome-TMCO1 translocon	Electron microscopy	3.84	2020-09-02
72	8FKU\|1\|L3+ 8FKU\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nucleolar pre-60S ribosomal subunit (State C2)	Electron microscopy	2.82	2023-07-12
73	8FKT\|1\|L3+ 8FKT\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nucleolar pre-60S ribosomal subunit (State C1)	Electron microscopy	2.81	2023-07-12
74	6IP5\|1\|1A+ 6IP5\|1\|1C	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)	Electron microscopy	3.9	2019-05-29
75	6IP8\|1\|1A+ 6IP8\|1\|1C	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)	Electron microscopy	3.9	2019-05-29
76	6OLZ\|1\|A2+ 6OLZ\|1\|A3	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA	Electron microscopy	3.9	2019-06-19
77	8BF9\|1\|5	Large subunit ribosomal RNA	RNA (1766)	Ovis aries	Eukarya	RF02543	Molecular view of ER membrane remodeling by the Sec61/TRAP translocon.	Electron microscopy	2.69	2023-11-01
78	5AJ0\|1\|A2+ 5AJ0\|1\|A3	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Cryo electron microscopy of actively translating human polysomes (POST state).	Electron microscopy	3.5	2015-05-20
79	8FKS\|1\|L3+ 8FKS\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nucleolar pre-60S ribosomal subunit (State B2)	Electron microscopy	2.88	2023-07-12
80	8FKR\|1\|L3+ 8FKR\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nucleolar pre-60S ribosomal subunit (State B1)	Electron microscopy	2.89	2023-07-12
81	8FKQ\|1\|L3+ 8FKQ\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nucleolar pre-60S ribosomal subunit (State A2)	Electron microscopy	2.76	2023-07-12
82	8FKP\|1\|L3+ 8FKP\|1\|L1	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S rRNA, 5.8S rRNA	Homo sapiens	Eukarya	RF02543 + RF00002	Human nucleolar pre-60S ribosomal subunit (State A1)	Electron microscopy	2.85	2023-07-12
83	8FL0\|1\|L3	Large subunit ribosomal RNA	28S rRNA	Homo sapiens	Eukarya	RF02543	Human nucleolar pre-60S ribosomal subunit (State H)	Electron microscopy	2.91	2023-07-12
84	5LKS\|1\|L5+ 5LKS\|1\|L8	Large subunit ribosomal RNA + 5.8S ribosomal RNA	28S ribosomal RNA, 5.8S ribosomal RNA	Homo sapiens	Eukarya	RF02543 + RF00002	Structure-function insights reveal the human ribosome as a cancer target for antibiotics	Electron microscopy	3.6	2017-04-26
85	6SXO\|1\|L5	Large subunit ribosomal RNA	28S ribosomal RNA including ES27L-B (2839-3265)	Homo sapiens	Eukarya	RF02543	Cryo-EM structure of the human Ebp1-ribosome complex	Electron microscopy	3.3	2020-02-19
86	7ZFW\|1\|L5	Large subunit ribosomal RNA	RNA (615-MER)	Homo sapiens	Eukarya	RF02543	Structure of human 80S ribosome obtained from ssDNA coated grid	Electron microscopy	3.8	2022-11-23
87	5A8L\|1\|A	Large subunit ribosomal RNA	28S RIBOSOMAL RNA	Homo sapiens	Eukarya	RF02543	Human eRF1 and the hCMV nascent peptide in the translation termination complex	Electron microscopy	3.8	2015-12-02

Release history

Release	3.312	3.313	3.314	3.315	3.316	3.317	3.318	3.319	3.320
Date	2023-12-06	2023-12-13	2023-12-20	2023-12-27	2024-01-03	2024-01-10	2024-01-17	2024-01-24	2024-01-31

Parents

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This class	Descendant classes	Release id	Intersection	Only in this class	Added to child

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. Instances are ordered to put similar structures near each other. The colorbar ranges from 0 to the maximum observed discrepancy, up to 0.5

#S - ordering by similarity (same as in the heat map).

#S	PDB	Title	Method	Resolution	Length
1	5A8L\|1\|A	Human eRF1 and the hCMV nascent peptide in the translation termination complex	ELECTRON MICROSCOPY	3.8	253
2	6LQM\|1\|2+6LQM\|1\|8	Cryo-EM structure of a pre-60S ribosomal subunit - state C	ELECTRON MICROSCOPY	3.09	3433
3	6Z6L\|1\|L5+6Z6L\|1\|L8	Cryo-EM structure of human CCDC124 bound to 80S ribosomes	ELECTRON MICROSCOPY	3	3772
4	7XNX\|1\|L1+7XNX\|1\|L3	High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells	ELECTRON MICROSCOPY	2.7	3686
5	7XNY\|1\|L1+7XNY\|1\|L3	High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells	ELECTRON MICROSCOPY	2.5	3686
6	8IR3\|1\|2+8IR3\|1\|8	human nuclear pre-60S ribosomal particle - State B'	ELECTRON MICROSCOPY	3.5	3477
7	8IR1\|1\|2+8IR1\|1\|8	human nuclear pre-60S ribosomal particle - State A	ELECTRON MICROSCOPY	3.3	3308
8	8FKZ\|1\|L3+8FKZ\|1\|L1	Human nucleolar pre-60S ribosomal subunit (State G)	ELECTRON MICROSCOPY	3.04	2833
9	8FL2\|1\|L3+8FL2\|1\|L1	Human nuclear pre-60S ribosomal subunit (State I1)	ELECTRON MICROSCOPY	2.67	3370
10	8FL3\|1\|L3+8FL3\|1\|L1	Human nuclear pre-60S ribosomal subunit (State I2)	ELECTRON MICROSCOPY	2.53	3369
11	8FL4\|1\|L3+8FL4\|1\|L1	Human nuclear pre-60S ribosomal subunit (State I3)	ELECTRON MICROSCOPY	2.89	3361
12	8IPY\|1\|2+8IPY\|1\|8	human nuclear pre-60S ribosomal particle - State D'	ELECTRON MICROSCOPY	3.2	3419
13	8INK\|1\|2+8INK\|1\|8	human nuclear pre-60S ribosomal particle - State D	ELECTRON MICROSCOPY	3.2	3428
14	8IPD\|1\|2+8IPD\|1\|8	human nuclear pre-60S ribosomal particle - State C	ELECTRON MICROSCOPY	3.2	3418
15	8IE3\|1\|2+8IE3\|1\|8	human nuclear pre-60S ribosomal particle - State E	ELECTRON MICROSCOPY	3.3	3449
16	6LU8\|1\|2+6LU8\|1\|8	Cryo-EM structure of a human pre-60S ribosomal subunit - state A	ELECTRON MICROSCOPY	3.13	3386
17	6LSS\|1\|2+6LSS\|1\|8	Cryo-EM structure of a pre-60S ribosomal subunit - state preA	ELECTRON MICROSCOPY	3.23	3383
18	8IDT\|1\|2+8IDT\|1\|8	human nuclear pre-60S ribosomal particle - State G	ELECTRON MICROSCOPY	2.8	3445
19	8IDY\|1\|2+8IDY\|1\|8	human nuclear pre-60S ribosomal particle - State F	ELECTRON MICROSCOPY	3	3564
20	8INF\|1\|2+8INF\|1\|8	human nuclear pre-60S ribosomal particle - State F'	ELECTRON MICROSCOPY	3	3579
21	8INE\|1\|2+8INE\|1\|8	human nuclear pre-60S ribosomal particle - State G'	ELECTRON MICROSCOPY	3.2	3461
22	8FLB\|1\|L3+8FLB\|1\|L1	Human nuclear pre-60S ribosomal subunit (State K2)	ELECTRON MICROSCOPY	2.55	3316
23	8FLA\|1\|L3+8FLA\|1\|L1	Human nuclear pre-60S ribosomal subunit (State K1)	ELECTRON MICROSCOPY	2.63	3316
24	8FL6\|1\|L3+8FL6\|1\|L1	Human nuclear pre-60S ribosomal subunit (State J1)	ELECTRON MICROSCOPY	2.62	3302
25	8FL7\|1\|L3+8FL7\|1\|L1	Human nuclear pre-60S ribosomal subunit (State J2)	ELECTRON MICROSCOPY	2.55	3306
26	8FLD\|1\|L3+8FLD\|1\|L1	Human nuclear pre-60S ribosomal subunit (State L1)	ELECTRON MICROSCOPY	2.58	3266
27	8FLE\|1\|L3+8FLE\|1\|L1	Human nuclear pre-60S ribosomal subunit (State L2)	ELECTRON MICROSCOPY	2.48	3266
28	8FLF\|1\|L3+8FLF\|1\|L1	Human nuclear pre-60S ribosomal subunit (State L3)	ELECTRON MICROSCOPY	2.65	3219
29	8FL9\|1\|L3+8FL9\|1\|L1	Human nuclear pre-60S ribosomal subunit (State J3)	ELECTRON MICROSCOPY	2.75	3258
30	8FLC\|1\|L3+8FLC\|1\|L1	Human nuclear pre-60S ribosomal subunit (State K3)	ELECTRON MICROSCOPY	2.76	3269
31	8G61\|1\|L5+8G61\|1\|L8	mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)	ELECTRON MICROSCOPY	2.94	3528
32	8G5Y\|1\|L5+8G5Y\|1\|L8	mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)	ELECTRON MICROSCOPY	2.29	3594
33	8GLP\|1\|L5+8GLP\|1\|L8	mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)	ELECTRON MICROSCOPY	1.67	3418
34	8G6J\|1\|L5+8G6J\|1\|L8	mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)	ELECTRON MICROSCOPY	2.8	3559
35	8G5Z\|1\|L5+8G5Z\|1\|L8	mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)	ELECTRON MICROSCOPY	2.64	3560
36	7OW7\|1\|A+7OW7\|1\|C	EIF6-bound large subunit of the human ribosome	ELECTRON MICROSCOPY	2.2	3190
37	8A3D\|1\|A+8A3D\|1\|C	Human mature large subunit of the ribosome with eIF6 and homoharringtonine bound	ELECTRON MICROSCOPY	1.67	3190
38	8G60\|1\|L5+8G60\|1\|L8	mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)	ELECTRON MICROSCOPY	2.54	3509
39	8JDM\|1\|D	Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (rotated state)	ELECTRON MICROSCOPY	2.67	3399
40	8JDK\|1\|D	Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)	ELECTRON MICROSCOPY	2.26	3399
41	8JDJ\|1\|D	Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU)	ELECTRON MICROSCOPY	2.5	3399
42	8JDL\|1\|D	Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state)	ELECTRON MICROSCOPY	2.42	3399
43	7BHP\|1\|L5+7BHP\|1\|L8	Cryo-EM structure of the human Ebp1 - 80S ribosome	ELECTRON MICROSCOPY	3.3	3644
44	7QVP\|1\|L5+7QVP\|1\|L8	Human collided disome (di-ribosome) stalled on XBP1 mRNA	ELECTRON MICROSCOPY	3	3611
45	6Y2L\|1\|L5+6Y2L\|1\|L8	Structure of human ribosome in POST state	ELECTRON MICROSCOPY	3	3613
46	6Y0G\|1\|L5+6Y0G\|1\|L8	Structure of human ribosome in classical-PRE state	ELECTRON MICROSCOPY	3.2	3644
47	6QZP\|1\|L5+6QZP\|1\|L8	High-resolution cryo-EM structure of the human 80S ribosome	ELECTRON MICROSCOPY	2.9	3696
48	6Y6X\|1\|L5+6Y6X\|1\|L8	Tetracenomycin X bound to the human ribosome	ELECTRON MICROSCOPY	2.8	3773
49	6Z6N\|1\|L5+6Z6N\|1\|L8	Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)	ELECTRON MICROSCOPY	2.9	3772
50	6ZM7\|1\|L5+6ZM7\|1\|L8	SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex	ELECTRON MICROSCOPY	2.7	3773
51	6ZMI\|1\|L5+6ZMI\|1\|L8	SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex	ELECTRON MICROSCOPY	2.6	3773
52	6ZMO\|1\|L5+6ZMO\|1\|L8	SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex	ELECTRON MICROSCOPY	3.1	3773
53	6ZME\|1\|L5+6ZME\|1\|L8	SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex	ELECTRON MICROSCOPY	3	3773
54	6Z6M\|1\|L5+6Z6M\|1\|L8	Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1	ELECTRON MICROSCOPY	3.1	3772
55	7QVP\|1\|L6+7QVP\|1\|L1	Human collided disome (di-ribosome) stalled on XBP1 mRNA	ELECTRON MICROSCOPY	3	3572
56	6Y57\|1\|L5+6Y57\|1\|L8	Structure of human ribosome in hybrid-PRE state	ELECTRON MICROSCOPY	3.5	3574
57	7F5S\|1\|L5+7F5S\|1\|L8	human delta-METTL18 60S ribosome	ELECTRON MICROSCOPY	2.72	3575
58	6XA1\|1\|L5+6XA1\|1\|L8	Structure of a drug-like compound stalled human translation termination complex	ELECTRON MICROSCOPY	2.8	3390
59	6IP8\|1\|1A+6IP8\|1\|1C	Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)	ELECTRON MICROSCOPY	3.9	3667
60	6IP5\|1\|1A+6IP5\|1\|1C	Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)	ELECTRON MICROSCOPY	3.9	3717
61	6W6L\|1\|t+6W6L\|1\|D	Cryo-EM structure of the human ribosome-TMCO1 translocon	ELECTRON MICROSCOPY	3.84	3510
62	6OM7\|1\|t+6OM7\|1\|D	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs	ELECTRON MICROSCOPY	3.7	3607
63	6OLF\|1\|t+6OLF\|1\|D	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs	ELECTRON MICROSCOPY	3.9	3607
64	6OLI\|1\|t+6OLI\|1\|D	Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)	ELECTRON MICROSCOPY	3.5	3607
65	6OLE\|1\|t+6OLE\|1\|D	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs	ELECTRON MICROSCOPY	3.1	3607
66	6OM0\|1\|t+6OM0\|1\|D	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs	ELECTRON MICROSCOPY	3.1	3607
67	6OLZ\|1\|A2+6OLZ\|1\|A3	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA	ELECTRON MICROSCOPY	3.9	3643
68	6OLG\|1\|A2+6OLG\|1\|A3	Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)	ELECTRON MICROSCOPY	3.4	3612
69	5AJ0\|1\|A2+5AJ0\|1\|A3	Cryo electron microscopy of actively translating human polysomes (POST state).	ELECTRON MICROSCOPY	3.5	3612
70	4UG0\|1\|L5+4UG0\|1\|L8	STRUCTURE OF THE HUMAN 80S RIBOSOME	ELECTRON MICROSCOPY	3.6	3776
71	5T2C\|1\|A+5T2C\|1\|C	CryoEM structure of the human ribosome at 3.6 Angstrom resolution	ELECTRON MICROSCOPY	3.6	3776
72	5LKS\|1\|L5+5LKS\|1\|L8	Structure-function insights reveal the human ribosome as a cancer target for antibiotics	ELECTRON MICROSCOPY	3.6	3776
73	6LSR\|1\|2+6LSR\|1\|8	Cryo-EM structure of a pre-60S ribosomal subunit - state B	ELECTRON MICROSCOPY	3.13	3384
74	6SXO\|1\|L5	Cryo-EM structure of the human Ebp1-ribosome complex	ELECTRON MICROSCOPY	3.3	268
75	7ZFW\|1\|L5	Structure of human 80S ribosome obtained from ssDNA coated grid	ELECTRON MICROSCOPY	3.8	612
76	8FL0\|1\|L3	Human nucleolar pre-60S ribosomal subunit (State H)	ELECTRON MICROSCOPY	2.91	1558
77	8FKW\|1\|L3+8FKW\|1\|L1	Human nucleolar pre-60S ribosomal subunit (State D2)	ELECTRON MICROSCOPY	2.5	2277
78	8FKU\|1\|L3+8FKU\|1\|L1	Human nucleolar pre-60S ribosomal subunit (State C2)	ELECTRON MICROSCOPY	2.82	2185
79	8FKX\|1\|L3+8FKX\|1\|L1	Human nucleolar pre-60S ribosomal subunit (State E)	ELECTRON MICROSCOPY	2.59	2250
80	8FKY\|1\|L3+8FKY\|1\|L1	Human nucleolar pre-60S ribosomal subunit (State F)	ELECTRON MICROSCOPY	2.67	2585
81	8FKT\|1\|L3+8FKT\|1\|L1	Human nucleolar pre-60S ribosomal subunit (State C1)	ELECTRON MICROSCOPY	2.81	2125
82	8FKV\|1\|L3+8FKV\|1\|L1	Human nucleolar pre-60S ribosomal subunit (State D1)	ELECTRON MICROSCOPY	2.47	2213
83	8FKS\|1\|L3+8FKS\|1\|L1	Human nucleolar pre-60S ribosomal subunit (State B2)	ELECTRON MICROSCOPY	2.88	1824
84	8FKQ\|1\|L3+8FKQ\|1\|L1	Human nucleolar pre-60S ribosomal subunit (State A2)	ELECTRON MICROSCOPY	2.76	1565
85	8FKR\|1\|L3+8FKR\|1\|L1	Human nucleolar pre-60S ribosomal subunit (State B1)	ELECTRON MICROSCOPY	2.89	1767
86	8FKP\|1\|L3+8FKP\|1\|L1	Human nucleolar pre-60S ribosomal subunit (State A1)	ELECTRON MICROSCOPY	2.85	1507
87	8BF9\|1\|5	Molecular view of ER membrane remodeling by the Sec61/TRAP translocon.	ELECTRON MICROSCOPY	2.69	1766

Equivalence class NR_4.0_65061.23 Obsolete

Release history

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