Equivalence class NR_all_10255.8 Obsolete
| # | IFE | Standardized name | Molecule | Organism | Source | Rfam | Title | Method | Res. Å | Date |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 6D9J|1|7 (rep) | 5S ribosomal RNA | 5S rRNA | Oryctolagus cuniculus | Eukarya | RF00001 | Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1. | Electron microscopy | 3.2 | 2018-06-06 |
| 2 | 5LZS|1|7 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B | Electron microscopy | 3.31 | 2016-11-30 |
| 3 | 5LZV|1|7 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of the mammalian ribosomal termination complex with accommodated eRF1(AAQ) and ABCE1. | Electron microscopy | 3.35 | 2016-11-30 |
| 4 | 6MTD|1|7 | 5S ribosomal RNA | 5S rRNA | Oryctolagus cuniculus | Eukarya | RF00001 | Rabbit 80S ribosome with eEF2 and SERBP1 (unrotated state with 40S head swivel) | Electron microscopy | 3.3 | 2018-11-21 |
| 5 | 1VWY|1|7 | 5S ribosomal RNA | Structure of the idle mammalian ribosome-Sec61 complex. This entry contains the large subunit ribosomal RNA. | Electron microscopy | 3.4 | 2014-06-18 | ||||
| 6 | 1VWW|1|7 | 5S ribosomal RNA | Structure of the mammalian 60S ribosomal subunit. This entry contains the large subunit ribosomal RNA. | Electron microscopy | 3.4 | 2014-06-18 | ||||
| 7 | 3J71|1|7 | 5S ribosomal RNA | Structure of the mammalian 60S ribosomal subunit | Electron microscopy | 3.4 | 2014-06-18 | ||||
| 8 | 3J72|1|7 | 5S ribosomal RNA | Structure of the idle mammalian ribosome-Sec61 complex | Electron microscopy | 3.4 | 2014-06-18 | ||||
| 9 | 6MTE|1|7 | 5S ribosomal RNA | 5S rRNA | Oryctolagus cuniculus | Eukarya | RF00001 | Rabbit 80S ribosome with eEF2 and SERBP1 (rotated state) | Electron microscopy | 3.4 | 2018-11-21 |
| 10 | 1VX3|1|7 | 5S ribosomal RNA | Structure of the 80S mammalian ribosome bound to eEF2. This entry contains the large subunit ribosomal RNA. | Electron microscopy | 3.5 | 2014-06-18 | ||||
| 11 | 3J74|1|7 | 5S ribosomal RNA | Structure of the 80S mammalian ribosome bound to eEF2 | Electron microscopy | 3.5 | 2014-06-18 | ||||
| 12 | 5LZZ|1|7 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of the mammalian rescue complex with Pelota and Hbs1l (combined) | Electron microscopy | 3.47 | 2016-11-30 |
| 13 | 6MTC|1|7 | 5S ribosomal RNA | 5S rRNA | Oryctolagus cuniculus | Eukarya | RF00001 | Rabbit 80S ribosome with Z-site tRNA and IFRD2 (unrotated state) | Electron microscopy | 3.4 | 2018-11-21 |
| 14 | 5LZW|1|7 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA. | Electron microscopy | 3.53 | 2016-11-30 |
| 15 | 6D90|1|7 | 5S ribosomal RNA | 5S rRNA | Oryctolagus cuniculus | Eukarya | RF00001 | Mammalian 80S ribosome with a double translocated CrPV-IRES, P-site tRNA and eRF1. | Electron microscopy | 3.2 | 2018-06-06 |
| 16 | 5LZT|1|7 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of the mammalian ribosomal termination complex with eRF1 and eRF3. | Electron microscopy | 3.65 | 2016-11-30 |
| 17 | 5LZX|1|7 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon. | Electron microscopy | 3.67 | 2016-11-30 |
| 18 | 6GZ5|1|A4 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-3 (TI-POST-3) | Electron microscopy | 3.5 | 2018-12-05 |
| 19 | 6MTB|1|7 | 5S ribosomal RNA | 5S rRNA | Oryctolagus cuniculus | Eukarya | RF00001 | Rabbit 80S ribosome with P- and Z-site tRNAs (unrotated state) | Electron microscopy | 3.6 | 2018-11-21 |
| 20 | 6GZ3|1|A4 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-1 (TI-POST-1) | Electron microscopy | 3.6 | 2018-12-05 |
| 21 | 6FRK|1|7 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of a prehandover mammalian ribosomal SRP and SRP receptor targeting complex | Electron microscopy | 3.7 | 2018-03-28 |
| 22 | 5LZU|1|7 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of the mammalian ribosomal termination complex with accommodated eRF1 | Electron microscopy | 3.75 | 2016-11-30 |
| 23 | 6GZ4|1|A4 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-2 (TI-POST-2) | Electron microscopy | 3.6 | 2018-12-05 |
| 24 | 6HCJ|1|71 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs | Electron microscopy | 3.8 | 2018-10-17 |
| 25 | 3JAH|1|7 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAG stop codon | Electron microscopy | 3.45 | 2015-08-12 |
| 26 | 1VX0|1|7 | 5S ribosomal RNA | Structure of the translating mammalian ribosome-Sec61 complex. This entry contains the large subunit ribosomal RNA. | Electron microscopy | 3.9 | 2014-06-18 | ||||
| 27 | 3J73|1|7 | 5S ribosomal RNA | Structure of the translating mammalian ribosome-Sec61 complex | Electron microscopy | 3.9 | 2014-06-18 | ||||
| 28 | 3J92|1|7 | 5S ribosomal RNA | 5S rRNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure and assembly pathway of the ribosome quality control complex | Electron microscopy | 3.6 | 2015-01-21 |
| 29 | 5LZY|1|7 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a polyadenylated mRNA. | Electron microscopy | 3.99 | 2016-11-30 |
| 30 | 3JAG|1|7 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon | Electron microscopy | 3.65 | 2015-08-12 |
| 31 | 3JAI|1|7 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UGA stop codon | Electron microscopy | 3.65 | 2015-08-12 |
| 32 | 6HCF|1|72 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of the rabbit 80S ribosome stalled on globin mRNA at the stop codon | Electron microscopy | 3.9 | 2018-10-17 |
| 33 | 6FTI|1|v | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Programmed 80S Ribosome | Electron microscopy | 4.2 | 2018-03-21 |
| 34 | 6FTJ|1|v | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Non-programmed 80S Ribosome | Electron microscopy | 4.7 | 2018-03-21 |
| 35 | 6HCQ|1|71 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of the rabbit collided di-ribosome (collided monosome) | Electron microscopy | 6.5 | 2018-10-17 |
| 36 | 6HCM|1|72 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of the rabbit collided di-ribosome (stalled monosome) | Electron microscopy | 6.8 | 2018-10-17 |
| 37 | 4UJE|1|A4 | 5S ribosomal RNA | 5S Ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Regulation of the mammalian elongation cycle by 40S subunit rolling: a eukaryotic-specific ribosome rearrangement | Electron microscopy | 6.9 | 2014-07-16 |
| 38 | 3JAN|1|7 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of the scanning state of the mammalian SRP-ribosome complex | Electron microscopy | 3.75 | 2015-08-05 |
| 39 | 3JAJ|1|7 | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Structure of the engaged state of the mammalian SRP-ribosome complex | Electron microscopy | 3.75 | 2015-08-05 |
| 40 | 6FTG|1|v | 5S ribosomal RNA | 5S ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Subtomogram average of OST-containing ribosome-translocon complexes from canine rough microsomal membranes | Electron microscopy | 9.1 | 2018-03-21 |
| 41 | 4UJD|1|A4 | 5S ribosomal RNA | 5S Ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | mammalian 80S HCV-IRES initiation complex with eIF5B PRE-like state | Electron microscopy | 8.9 | 2014-07-30 |
| 42 | 4D5Y|1|4 | 5S ribosomal RNA | 5S Ribosomal RNA | Oryctolagus cuniculus | Eukarya | RF00001 | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | Electron microscopy | 9 | 2015-03-04 |
| 43 | 4D67|1|4 | 5S ribosomal RNA | 5S RRNA | Oryctolagus cuniculus | Eukarya | RF00001 | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | Electron microscopy | 9 | 2015-03-04 |
| 44 | 4UJC|1|A4 | 5S ribosomal RNA | 5S RIBOSOMAL RNA | Oryctolagus cuniculus | Eukarya | RF00001 | mammalian 80S HCV-IRES initiation complex with eIF5B POST-like state | Electron microscopy | 9.5 | 2014-07-30 |
Release history
| Release | 3.51 | 3.52 | 3.53 | 3.54 | 3.55 | 3.56 | 3.57 | 3.58 | 3.59 | 3.60 | 3.61 | 3.62 | 3.63 | 3.64 | 3.65 | 3.66 | 3.67 | 3.68 | 3.69 | 3.70 | 3.71 | 3.72 | 3.73 | 3.74 | 3.75 | 3.76 | 3.77 | 3.78 | 3.79 | 3.80 | 3.81 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Date | 2018-12-07 | 2018-12-14 | 2018-12-21 | 2018-12-28 | 2019-01-04 | 2019-01-11 | 2019-01-18 | 2019-01-25 | 2019-02-01 | 2019-02-08 | 2019-02-15 | 2019-02-22 | 2019-03-01 | 2019-03-08 | 2019-03-15 | 2019-03-22 | 2019-03-29 | 2019-04-05 | 2019-04-12 | 2019-04-19 | 2019-04-26 | 2019-05-03 | 2019-05-10 | 2019-05-17 | 2019-05-24 | 2019-05-31 | 2019-06-07 | 2019-06-14 | 2019-06-21 | 2019-06-28 | 2019-07-05 |
Parents
| This class | Parent classes | Release id | Intersection | Added to this class | Only in parent |
|---|---|---|---|---|---|
| NR_all_10255.8 | NR_all_10255.7 | 3.51 | (41) 3J72|1|7, 6MTB|1|7, 4UJC|1|A4, 5LZZ|1|7, 4D67|1|4, 3J71|1|7, 6HCQ|1|71, 5LZY|1|7, 4D5Y|1|4, 6HCM|1|72, 1VX3|1|7, 5LZX|1|7, 3JAN|1|7, 6HCJ|1|71, 1VX0|1|7, 5LZW|1|7, 3JAJ|1|7, 6HCF|1|72, 1VWY|1|7, 5LZV|1|7, 3JAI|1|7, 6FTJ|1|v, 1VWW|1|7, 5LZU|1|7, 3JAH|1|7, 6FTI|1|v, 5LZT|1|7, 3JAG|1|7, 6FTG|1|v, 5LZS|1|7, 3J92|1|7, 6MTE|1|7, 6FRK|1|7, 4UJE|1|A4, 3J74|1|7, 6MTD|1|7, 6D9J|1|7, 4UJD|1|A4, 3J73|1|7, 6MTC|1|7, 6D90|1|7 | (3) 6GZ4|1|A4, 6GZ3|1|A4, 6GZ5|1|A4 | (0) |
Children
| This class | Descendant classes | Release id | Intersection | Only in this class | Added to child |
|---|
Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. Instances are ordered to put similar structures near each other. The colorbar ranges from 0 to the maximum observed discrepancy, up to 0.5
#S - ordering by similarity (same as in the heat map).| #S | PDB | Title | Method | Resolution | Length |
|---|---|---|---|---|---|
| 1 | 4D5Y|1|4 | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | ELECTRON MICROSCOPY | 9 | 119 |
| 2 | 4D67|1|4 | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | ELECTRON MICROSCOPY | 9 | 119 |
| 3 | 4UJC|1|A4 | mammalian 80S HCV-IRES initiation complex with eIF5B POST-like state | ELECTRON MICROSCOPY | 9.5 | 119 |
| 4 | 4UJD|1|A4 | mammalian 80S HCV-IRES initiation complex with eIF5B PRE-like state | ELECTRON MICROSCOPY | 8.9 | 119 |
| 5 | 4UJE|1|A4 | Regulation of the mammalian elongation cycle by 40S subunit rolling: a eukaryotic-specific ribosome rearrangement | ELECTRON MICROSCOPY | 6.9 | 119 |
| 6 | 3JAN|1|7 | Structure of the scanning state of the mammalian SRP-ribosome complex | ELECTRON MICROSCOPY | 3.75 | 120 |
| 7 | 3JAJ|1|7 | Structure of the engaged state of the mammalian SRP-ribosome complex | ELECTRON MICROSCOPY | 3.75 | 120 |
| 8 | 6FRK|1|7 | Structure of a prehandover mammalian ribosomal SRP and SRP receptor targeting complex | ELECTRON MICROSCOPY | 3.7 | 120 |
| 9 | 3J92|1|7 | Structure and assembly pathway of the ribosome quality control complex | ELECTRON MICROSCOPY | 3.6 | 120 |
| 10 | 3JAG|1|7 | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon | ELECTRON MICROSCOPY | 3.65 | 120 |
| 11 | 6FTG|1|v | Subtomogram average of OST-containing ribosome-translocon complexes from canine rough microsomal membranes | ELECTRON MICROSCOPY | 9.1 | 120 |
| 12 | 6FTI|1|v | Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Programmed 80S Ribosome | ELECTRON MICROSCOPY | 4.2 | 120 |
| 13 | 6FTJ|1|v | Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Non-programmed 80S Ribosome | ELECTRON MICROSCOPY | 4.7 | 120 |
| 14 | 3JAH|1|7 | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAG stop codon | ELECTRON MICROSCOPY | 3.45 | 120 |
| 15 | 3JAI|1|7 | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UGA stop codon | ELECTRON MICROSCOPY | 3.65 | 120 |
| 16 | 5LZY|1|7 | Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a polyadenylated mRNA. | ELECTRON MICROSCOPY | 3.99 | 120 |
| 17 | 5LZZ|1|7 | Structure of the mammalian rescue complex with Pelota and Hbs1l (combined) | ELECTRON MICROSCOPY | 3.47 | 120 |
| 18 | 5LZX|1|7 | Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon. | ELECTRON MICROSCOPY | 3.67 | 120 |
| 19 | 5LZW|1|7 | Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA. | ELECTRON MICROSCOPY | 3.53 | 120 |
| 20 | 5LZT|1|7 | Structure of the mammalian ribosomal termination complex with eRF1 and eRF3. | ELECTRON MICROSCOPY | 3.65 | 120 |
| 21 | 5LZV|1|7 | Structure of the mammalian ribosomal termination complex with accommodated eRF1(AAQ) and ABCE1. | ELECTRON MICROSCOPY | 3.35 | 120 |
| 22 | 5LZU|1|7 | Structure of the mammalian ribosomal termination complex with accommodated eRF1 | ELECTRON MICROSCOPY | 3.75 | 120 |
| 23 | 5LZS|1|7 | Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B | ELECTRON MICROSCOPY | 3.31 | 119 |
| 24 | 6MTC|1|7 | Rabbit 80S ribosome with Z-site tRNA and IFRD2 (unrotated state) | ELECTRON MICROSCOPY | 3.4 | 120 |
| 25 | 6MTB|1|7 | Rabbit 80S ribosome with P- and Z-site tRNAs (unrotated state) | ELECTRON MICROSCOPY | 3.6 | 120 |
| 26 | 6MTD|1|7 | Rabbit 80S ribosome with eEF2 and SERBP1 (unrotated state with 40S head swivel) | ELECTRON MICROSCOPY | 3.3 | 120 |
| 27 | 6MTE|1|7 | Rabbit 80S ribosome with eEF2 and SERBP1 (rotated state) | ELECTRON MICROSCOPY | 3.4 | 120 |
| 28 | 6GZ3|1|A4 | tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-1 (TI-POST-1) | ELECTRON MICROSCOPY | 3.6 | 119 |
| 29 | 6GZ5|1|A4 | tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-3 (TI-POST-3) | ELECTRON MICROSCOPY | 3.5 | 119 |
| 30 | 6GZ4|1|A4 | tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-2 (TI-POST-2) | ELECTRON MICROSCOPY | 3.6 | 119 |
| 31 | 6D90|1|7 | Mammalian 80S ribosome with a double translocated CrPV-IRES, P-site tRNA and eRF1. | ELECTRON MICROSCOPY | 3.2 | 119 |
| 32 | 1VWY|1|7 | Structure of the idle mammalian ribosome-Sec61 complex. This entry contains the large subunit ribosomal RNA. | ELECTRON MICROSCOPY | 3.4 | 120 |
| 33 | 3J72|1|7 | Structure of the idle mammalian ribosome-Sec61 complex | ELECTRON MICROSCOPY | 3.4 | 120 |
| 34 | 3J71|1|7 | Structure of the mammalian 60S ribosomal subunit | ELECTRON MICROSCOPY | 3.4 | 120 |
| 35 | 1VWW|1|7 | Structure of the mammalian 60S ribosomal subunit. This entry contains the large subunit ribosomal RNA. | ELECTRON MICROSCOPY | 3.4 | 120 |
| 36 | 1VX3|1|7 | Structure of the 80S mammalian ribosome bound to eEF2. This entry contains the large subunit ribosomal RNA. | ELECTRON MICROSCOPY | 3.5 | 120 |
| 37 | 3J74|1|7 | Structure of the 80S mammalian ribosome bound to eEF2 | ELECTRON MICROSCOPY | 3.5 | 120 |
| 38 | 3J73|1|7 | Structure of the translating mammalian ribosome-Sec61 complex | ELECTRON MICROSCOPY | 3.9 | 120 |
| 39 | 1VX0|1|7 | Structure of the translating mammalian ribosome-Sec61 complex. This entry contains the large subunit ribosomal RNA. | ELECTRON MICROSCOPY | 3.9 | 120 |
| 40 | 6D9J|1|7 | Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1. | ELECTRON MICROSCOPY | 3.2 | 119 |
| 41 | 6HCF|1|72 | Structure of the rabbit 80S ribosome stalled on globin mRNA at the stop codon | ELECTRON MICROSCOPY | 3.9 | 120 |
| 42 | 6HCM|1|72 | Structure of the rabbit collided di-ribosome (stalled monosome) | ELECTRON MICROSCOPY | 6.8 | 120 |
| 43 | 6HCQ|1|71 | Structure of the rabbit collided di-ribosome (collided monosome) | ELECTRON MICROSCOPY | 6.5 | 120 |
| 44 | 6HCJ|1|71 | Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs | ELECTRON MICROSCOPY | 3.8 | 120 |