#IFECompound(s)RNA source organismTitleMethodResolutionDate
14ZT0|1|D (rep)single-guide RNAStreptococcus pyogenesCrystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolutionX-RAY DIFFRACTION2.92015-07-08
24ZT0|1|Bsingle-guide RNAStreptococcus pyogenesCrystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolutionX-RAY DIFFRACTION2.92015-07-08
34ZT9|1|Dsingle-guide RNAStreptococcus pyogenesNuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolutionX-RAY DIFFRACTION3.12015-07-08
44ZT9|1|Bsingle-guide RNAStreptococcus pyogenesNuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolutionX-RAY DIFFRACTION3.12015-07-08
57S4X|1|BgRNAsynthetic constructCas9:gRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformationELECTRON MICROSCOPY2.762022-03-02
66O0X|1|Bsingle guide RNAsynthetic constructConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.282019-07-10
77S4V|1|BgRNAsynthetic constructCas9 bound to 12-14MM DNA, 60 min time-point, kinked conformationELECTRON MICROSCOPY3.282022-03-02
86O0Y|1|Bsingle guide RNAsynthetic constructConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.372019-07-10
96O0Z|1|Bsingle guide RNAsynthetic constructConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.32019-07-10
107S4U|1|BgRNAsynthetic constructCryo-EM structure of Cas9 in complex with 12-14MM DNA substrate, 5 minute time-pointELECTRON MICROSCOPY3.562022-03-02

Release history

Release3.2203.2213.2223.2233.2243.2253.2263.2273.2283.2293.2303.2313.2323.2333.2343.2353.2363.2373.2383.2393.2403.2413.2423.2433.2443.245
Date2022-03-022022-03-092022-03-162022-03-232022-03-302022-04-062022-04-132022-04-202022-04-272022-05-042022-05-112022-05-182022-05-252022-06-012022-06-082022-06-152022-06-222022-06-292022-07-062022-07-132022-07-202022-07-272022-08-032022-08-102022-08-172022-08-24

Parents

This classParent classesRelease idIntersectionAdded to this classOnly in parent
NR_all_30925.2NR_all_30925.13.220(7) 4ZT0|1|B, 6O0Z|1|B, 6O0Y|1|B, 6O0X|1|B, 4ZT9|1|D, 4ZT9|1|B, 4ZT0|1|D(3) 7S4X|1|B, 7S4V|1|B, 7S4U|1|B(0)

Children

This class Descendant classesRelease idIntersectionOnly in this classAdded to child
NR_all_30925.2NR_all_20965.13.246(10) 7S4V|1|B, 4ZT0|1|B, 4ZT9|1|B, 4ZT9|1|D, 6O0Y|1|B, 6O0Z|1|B, 7S4X|1|B, 4ZT0|1|D, 6O0X|1|B, 7S4U|1|B(0) (10) 7Z4H|1|A, 7Z4D|1|A, 7Z4J|1|A, 7Z4E|1|A, 7Z4L|1|A, 7Z4G|1|A, 7Z4C|1|A, 7Z4I|1|A, 7Z4D|1|F, 7Z4K|1|A

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. Instances are ordered to put similar structures near each other. The colorbar ranges from 0 to the maximum observed discrepancy, up to 0.5

#S - ordering by similarity (same as in the heat map).
#SPDBTitleMethodResolutionLength
14ZT9|1|DNuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolutionX-RAY DIFFRACTION3.172
24ZT0|1|DCrystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolutionX-RAY DIFFRACTION2.972
34ZT0|1|BCrystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolutionX-RAY DIFFRACTION2.972
44ZT9|1|BNuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolutionX-RAY DIFFRACTION3.172
56O0Y|1|BConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.3798
66O0X|1|BConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.2898
77S4V|1|BCas9 bound to 12-14MM DNA, 60 min time-point, kinked conformationELECTRON MICROSCOPY3.2898
87S4X|1|BCas9:gRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformationELECTRON MICROSCOPY2.7698
96O0Z|1|BConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.396
107S4U|1|BCryo-EM structure of Cas9 in complex with 12-14MM DNA substrate, 5 minute time-pointELECTRON MICROSCOPY3.5697