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Equivalence class NR_all_73426.6 Current

#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodÅDate
17EVO|1|H (rep)U2 splicesomal small nuclear RNAU2 snRNAHomo sapiensEukaryaRF00004The cryo-EM structure of the human 17S U2 snRNPElectron microscopy2.52022-08-03
28HK1|1|HU2 snRNAHomo sapiensEukaryaThe cryo-EM structure of human pre-17S U2 snRNPElectron microscopy2.72023-03-08
37Q4O|1|2+ 7Q4O|1|hU2 splicesomal small nuclear RNAU2 snRNA, BPS oligoHomo sapiensEukarya + SyntheticRF00004Substrate-bound A-like U2 snRNPElectron microscopy2.22022-03-30
47Q4P|1|2U2 splicesomal small nuclear RNAU2 snRNAHomo sapiensEukaryaRF00004U2 snRNP after ATP-dependent remodelling snRNPElectron microscopy2.22022-03-30
57Q3L|1|2U2 splicesomal small nuclear RNAU2 snRNAHomo sapiensEukaryaRF00004Human 17S U2 snRNP 5' domainElectron microscopy2.32022-03-30
67VPX|1|HU2 snRNA, pre-mRNAHomo sapiensThe cryo-EM structure of the human pre-A complexElectron microscopy32023-05-03
76QX9|1|2U2 splicesomal small nuclear RNAU2 snRNA, U6 snRNA, AdML pre-mRNAHomo sapiensEukaryaRF00004Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).Electron microscopy3.282019-04-17
87ONB|1|HU2 splicesomal small nuclear RNARNU2, MINXHomo sapiensEukaryaRF00004Structure of the U2 5' module of the A3'-SSA complexElectron microscopy3.12021-08-04
96Y50|1|2U2 splicesomal small nuclear RNAU2 snRNAHomo sapiensEukaryaRF000045'domain of human 17S U2 snRNPElectron microscopy4.12020-07-01
107ABH|1|2U2 splicesomal small nuclear RNAU2 snRNA, MINX M3 pre-mRNAHomo sapiensEukaryaRF00004Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion)Electron microscopy4.52020-12-09
118CH6|1|f+ 8CH6|1|dRNU2-1, RNU6-1, MINX-M3Homo sapiensStructure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).Electron microscopy5.92023-05-10
125Z58|1|H+ 5Z58|1|FU2 splicesomal small nuclear RNA + U6 spliceosomal RNAU2 snRNA, U6 snRNA, pre-mRNAHomo sapiensEukaryaRF00004 + RF00026Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom.Electron microscopy4.92018-09-19
135MQF|1|2+ 5MQF|1|6U2 splicesomal small nuclear RNA + U6 spliceosomal RNAHuman gene for small nuclear RNA U2 (snRNA U2), Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), small nuclear RNA, MINX pre-mRNA (intron)Homo sapiensEukaryaRF00004 + RF00026Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex)Electron microscopy5.92017-03-22
145Z56|1|H+ 5Z56|1|FU2 splicesomal small nuclear RNA + U6 spliceosomal RNAU2 snRNA, U6 snRNA, pre-mRNAHomo sapiensEukaryaRF00004 + RF00026cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom.Electron microscopy5.12018-09-19
156Y5Q|1|2U2 splicesomal small nuclear RNAU2snRNAHomo sapiensEukaryaRF00004human 17S U2 snRNPElectron microscopy7.12020-06-17
166Y53|1|2U2 splicesomal small nuclear RNAU2 snRNAHomo sapiensEukaryaRF00004human 17S U2 snRNP low resolution partElectron microscopy7.12020-06-17
175Z57|1|H+ 5Z57|1|FU2 splicesomal small nuclear RNA + U6 spliceosomal RNAU2 snRNA, U6 snRNA, pre-mRNAHomo sapiensEukaryaRF00004 + RF00026Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstromElectron microscopy6.52018-09-19
187ABI|1|2+ 7ABI|1|6U2 splicesomal small nuclear RNA + U6 spliceosomal RNAU2 snRNA, U6 snRNA, MINX M3 pre-mRNAHomo sapiensEukaryaRF00004 + RF00026Human pre-Bact-2 spliceosomeElectron microscopy82021-02-10

Release history

Release3.282
Date2023-05-10

Parents

This classParent classesRelease idIntersectionAdded to this classOnly in parent
NR_all_73426.6NR_all_73426.53.282(17) 8HK1|1|H, 7VPX|1|H, 7Q4P|1|2, 7Q4O|1|2+7Q4O|1|h, 7Q3L|1|2, 7ONB|1|H, 7EVO|1|H, 7ABI|1|2+7ABI|1|6, 7ABH|1|2, 6Y5Q|1|2, 6Y53|1|2, 6Y50|1|2, 6QX9|1|2, 5Z58|1|H+5Z58|1|F, 5Z57|1|H+5Z57|1|F, 5Z56|1|H+5Z56|1|F, 5MQF|1|2+5MQF|1|6(1) 8CH6|1|f+8CH6|1|d(0)

Children

This class Descendant classesRelease idIntersectionOnly in this classAdded to child

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. Instances are ordered to put similar structures near each other. The colorbar ranges from 0 to the maximum observed discrepancy, up to 0.5

#S - ordering by similarity (same as in the heat map).
#SPDBTitleMethodResolutionLength
17Q4P|1|2U2 snRNP after ATP-dependent remodelling snRNPELECTRON MICROSCOPY2.231
27Q4O|1|2+7Q4O|1|hSubstrate-bound A-like U2 snRNPELECTRON MICROSCOPY2.224
37ONB|1|HStructure of the U2 5' module of the A3'-SSA complexELECTRON MICROSCOPY3.132
47VPX|1|HThe cryo-EM structure of the human pre-A complexELECTRON MICROSCOPY3130
57ABI|1|2+7ABI|1|6Human pre-Bact-2 spliceosomeELECTRON MICROSCOPY8164
68CH6|1|f+8CH6|1|dStructure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).ELECTRON MICROSCOPY5.9137
75Z58|1|H+5Z58|1|FCryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom.ELECTRON MICROSCOPY4.9136
85Z56|1|H+5Z56|1|Fcryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom.ELECTRON MICROSCOPY5.1136
95Z57|1|H+5Z57|1|FCryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstromELECTRON MICROSCOPY6.5136
107ABH|1|2Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion)ELECTRON MICROSCOPY4.537
116QX9|1|2Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).ELECTRON MICROSCOPY3.2894
127Q3L|1|2Human 17S U2 snRNP 5' domainELECTRON MICROSCOPY2.341
136Y50|1|25'domain of human 17S U2 snRNPELECTRON MICROSCOPY4.150
146Y5Q|1|2human 17S U2 snRNPELECTRON MICROSCOPY7.1148
158HK1|1|HThe cryo-EM structure of human pre-17S U2 snRNPELECTRON MICROSCOPY2.7148
167EVO|1|HThe cryo-EM structure of the human 17S U2 snRNPELECTRON MICROSCOPY2.5148
176Y53|1|2human 17S U2 snRNP low resolution partELECTRON MICROSCOPY7.198
185MQF|1|2+5MQF|1|6Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex)ELECTRON MICROSCOPY5.9140
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