HL_7QR8_003

3D structure

PDB id

7QR8 (explore in PDB, NAKB, or RNA 3D Hub)

Description

SpCas9 bound to PTPRC off-target1 DNA substrate

Experimental method

X-RAY DIFFRACTION

Resolution

2.75 Å

Loop

Sequence

UUGAAAAA

Length

8 nucleotides

Bulged bases

None detected

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

Detailed Annotation

GNRA with extra tWH

Broad Annotation

GNRA with extra tWH

Motif group

HL_04259.3

Basepair signature

cWW-F-F-F-F-F-F

Number of instances in this motif group

7

Unit IDs

7QR8|1|A|U|71
7QR8|1|A|U|72
7QR8|1|A|G|73
7QR8|1|A|A|74
7QR8|1|A|A|75
7QR8|1|A|A|76
7QR8|1|A|A|77
7QR8|1|A|A|78

Current chains

Chain A

PTPRC sgRNA

Nearby chains

Chain B

CRISPR-associated endonuclease Cas9/Csn1