3D structure

PDB id
8K2C (explore in PDB, NAKB, or RNA 3D Hub)
Description
Cryo-EM structure of the human 80S ribosome with Tigecycline
Experimental method
ELECTRON MICROSCOPY
Resolution
2.4 Å

Loop

Sequence
UGAGAGGUGUAGAAUAAGUGGGAGGCCCGGGCCGCCGGUGAAAUACCACUACUCUGAGCCCGGGGCGGGGUCCGCCGGCCCUGCGGGCCGCCGGUGAAAUACCACUACUCUG*A
Length
113 nucleotides
Bulged bases
8K2C|1|L5|G|3958, 8K2C|1|L5|A|3962, 8K2C|1|L5|G|4035, 8K2C|1|L5|C|4038, 8K2C|1|L5|U|4044, 8K2C|1|L5|C|4054, 8K2C|1|L5|G|4007, 8K2C|1|L5|C|4008, 8K2C|1|L5|C|4009, 8K2C|1|L5|C|4010, 8K2C|1|L5|G|4011, 8K2C|1|L5|G|4012, 8K2C|1|L5|G|4013, 8K2C|1|L5|G|4014, 8K2C|1|L5|C|4015, 8K2C|1|L5|G|4016, 8K2C|1|L5|G|4017, 8K2C|1|L5|G|4018, 8K2C|1|L5|G|4019, 8K2C|1|L5|U|4020, 8K2C|1|L5|C|4021, 8K2C|1|L5|C|4022, 8K2C|1|L5|G|4023, 8K2C|1|L5|C|4024, 8K2C|1|L5|C|4025, 8K2C|1|L5|G|4026, 8K2C|1|L5|G|4027, 8K2C|1|L5|C|4028, 8K2C|1|L5|C|4029, 8K2C|1|L5|C|4030, 8K2C|1|L5|U|4031, 8K2C|1|L5|G|4032, 8K2C|1|L5|C|4033, 8K2C|1|L5|G|4034, 8K2C|1|L5|G|4035, 8K2C|1|L5|C|4038, 8K2C|1|L5|G|4039, 8K2C|1|L5|G|4042, 8K2C|1|L5|U|4044, 8K2C|1|L5|G|4045, 8K2C|1|L5|C|4051, 8K2C|1|L5|C|4052, 8K2C|1|L5|A|4053, 8K2C|1|L5|C|4054
QA status
Missing nucleotides

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.
R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.
R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.
R3DMCS Rfam
Detailed Annotation
No text annotation
Broad Annotation
No text annotation
Motif group
Not in a motif group
Basepair signature
Not available
Number of instances in this motif group
0

Unit IDs

8K2C|1|L5|U|3950
8K2C|1|L5|G|3951
8K2C|1|L5|A|3952
8K2C|1|L5|G|3953
8K2C|1|L5|A|3954
8K2C|1|L5|G|3955
8K2C|1|L5|G|3956
8K2C|1|L5|U|3957
8K2C|1|L5|G|3958
8K2C|1|L5|U|3959
8K2C|1|L5|A|3960
8K2C|1|L5|G|3961
8K2C|1|L5|A|3962
8K2C|1|L5|A|3963
8K2C|1|L5|U|3964
8K2C|1|L5|A|3965
8K2C|1|L5|A|3966
8K2C|1|L5|G|3967
8K2C|1|L5|U|3968
8K2C|1|L5|G|3969
8K2C|1|L5|G|3970
8K2C|1|L5|G|3971
8K2C|1|L5|A|3972
8K2C|1|L5|G|3973
8K2C|1|L5|G|3974
8K2C|1|L5|C|3975
8K2C|1|L5|C|3976
8K2C|1|L5|C|3977
8K2C|1|L5|G|4034
8K2C|1|L5|G|4035
8K2C|1|L5|G|4036
8K2C|1|L5|C|4037
8K2C|1|L5|C|4038
8K2C|1|L5|G|4039
8K2C|1|L5|C|4040
8K2C|1|L5|C|4041
8K2C|1|L5|G|4042
8K2C|1|L5|G|4043
8K2C|1|L5|U|4044
8K2C|1|L5|G|4045
8K2C|1|L5|A|4046
8K2C|1|L5|A|4047
8K2C|1|L5|A|4048
8K2C|1|L5|U|4049
8K2C|1|L5|A|4050
8K2C|1|L5|C|4051
8K2C|1|L5|C|4052
8K2C|1|L5|A|4053
8K2C|1|L5|C|4054
8K2C|1|L5|U|4055
8K2C|1|L5|A|4056
8K2C|1|L5|C|4057
8K2C|1|L5|U|4058
8K2C|1|L5|C|4059
8K2C|1|L5|U|4060
8K2C|1|L5|G|4061
8K2C|1|L5|A|4062
8K2C|1|L5|G|4007
8K2C|1|L5|C|4008
8K2C|1|L5|C|4009
8K2C|1|L5|C|4010
8K2C|1|L5|G|4011
8K2C|1|L5|G|4012
8K2C|1|L5|G|4013
8K2C|1|L5|G|4014
8K2C|1|L5|C|4015
8K2C|1|L5|G|4016
8K2C|1|L5|G|4017
8K2C|1|L5|G|4018
8K2C|1|L5|G|4019
8K2C|1|L5|U|4020
8K2C|1|L5|C|4021
8K2C|1|L5|C|4022
8K2C|1|L5|G|4023
8K2C|1|L5|C|4024
8K2C|1|L5|C|4025
8K2C|1|L5|G|4026
8K2C|1|L5|G|4027
8K2C|1|L5|C|4028
8K2C|1|L5|C|4029
8K2C|1|L5|C|4030
8K2C|1|L5|U|4031
8K2C|1|L5|G|4032
8K2C|1|L5|C|4033
8K2C|1|L5|G|4034
8K2C|1|L5|G|4035
8K2C|1|L5|G|4036
8K2C|1|L5|C|4037
8K2C|1|L5|C|4038
8K2C|1|L5|G|4039
8K2C|1|L5|C|4040
8K2C|1|L5|C|4041
8K2C|1|L5|G|4042
8K2C|1|L5|G|4043
8K2C|1|L5|U|4044
8K2C|1|L5|G|4045
8K2C|1|L5|A|4046
8K2C|1|L5|A|4047
8K2C|1|L5|A|4048
8K2C|1|L5|U|4049
8K2C|1|L5|A|4050
8K2C|1|L5|C|4051
8K2C|1|L5|C|4052
8K2C|1|L5|A|4053
8K2C|1|L5|C|4054
8K2C|1|L5|U|4055
8K2C|1|L5|A|4056
8K2C|1|L5|C|4057
8K2C|1|L5|U|4058
8K2C|1|L5|C|4059
8K2C|1|L5|U|4060
8K2C|1|L5|G|4061
*
8K2C|1|L5|A|4062

Current chains

Chain L5
28S rRNA

Nearby chains

Chain CC
Transfer RNA; tRNA
Chain Li
60S ribosomal protein L36
Chain Lz
60S ribosomal protein L10a
Chain SB
40S ribosomal protein S3a

Coloring options:

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