HL_8XSX_060

3D structure

PDB id

8XSX (explore in PDB, NAKB, or RNA 3D Hub)

Description

Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2

Experimental method

ELECTRON MICROSCOPY

Resolution

2.4 Å

Loop

Sequence

UGAGAGGUGUAGAAUAAGUGGGAGGCCCGGGCCGCCGGUGAAAUACCACUACUCUGAGCCCGGGGCGGGGUCCGCCGGCCCUGCGGGCCGCCGGUGAAAUACCACUACUCUG*A

Length

113 nucleotides

Bulged bases

8XSX|1|L5|G|3958, 8XSX|1|L5|A|3962, 8XSX|1|L5|G|4035, 8XSX|1|L5|C|4038, 8XSX|1|L5|U|4044, 8XSX|1|L5|C|4054, 8XSX|1|L5|G|4007, 8XSX|1|L5|C|4008, 8XSX|1|L5|C|4009, 8XSX|1|L5|C|4010, 8XSX|1|L5|G|4011, 8XSX|1|L5|G|4012, 8XSX|1|L5|G|4013, 8XSX|1|L5|G|4014, 8XSX|1|L5|C|4015, 8XSX|1|L5|G|4016, 8XSX|1|L5|G|4017, 8XSX|1|L5|G|4018, 8XSX|1|L5|G|4019, 8XSX|1|L5|U|4020, 8XSX|1|L5|C|4021, 8XSX|1|L5|C|4022, 8XSX|1|L5|G|4023, 8XSX|1|L5|C|4024, 8XSX|1|L5|C|4025, 8XSX|1|L5|G|4026, 8XSX|1|L5|G|4027, 8XSX|1|L5|C|4028, 8XSX|1|L5|C|4029, 8XSX|1|L5|C|4030, 8XSX|1|L5|U|4031, 8XSX|1|L5|G|4032, 8XSX|1|L5|C|4033, 8XSX|1|L5|G|4034, 8XSX|1|L5|G|4035, 8XSX|1|L5|C|4038, 8XSX|1|L5|G|4039, 8XSX|1|L5|G|4042, 8XSX|1|L5|U|4044, 8XSX|1|L5|G|4045, 8XSX|1|L5|C|4051, 8XSX|1|L5|C|4052, 8XSX|1|L5|A|4053, 8XSX|1|L5|C|4054

QA status

Missing nucleotides

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

Detailed Annotation

No text annotation

Broad Annotation

No text annotation

Motif group

Not in a motif group

Basepair signature

Not available

Number of instances in this motif group

0

Unit IDs

8XSX|1|L5|U|3950
8XSX|1|L5|G|3951
8XSX|1|L5|A|3952
8XSX|1|L5|G|3953
8XSX|1|L5|A|3954
8XSX|1|L5|G|3955
8XSX|1|L5|G|3956
8XSX|1|L5|U|3957
8XSX|1|L5|G|3958
8XSX|1|L5|U|3959
8XSX|1|L5|A|3960
8XSX|1|L5|G|3961
8XSX|1|L5|A|3962
8XSX|1|L5|A|3963
8XSX|1|L5|U|3964
8XSX|1|L5|A|3965
8XSX|1|L5|A|3966
8XSX|1|L5|G|3967
8XSX|1|L5|U|3968
8XSX|1|L5|G|3969
8XSX|1|L5|G|3970
8XSX|1|L5|G|3971
8XSX|1|L5|A|3972
8XSX|1|L5|G|3973
8XSX|1|L5|G|3974
8XSX|1|L5|C|3975
8XSX|1|L5|C|3976
8XSX|1|L5|C|3977
8XSX|1|L5|G|4034
8XSX|1|L5|G|4035
8XSX|1|L5|G|4036
8XSX|1|L5|C|4037
8XSX|1|L5|C|4038
8XSX|1|L5|G|4039
8XSX|1|L5|C|4040
8XSX|1|L5|C|4041
8XSX|1|L5|G|4042
8XSX|1|L5|G|4043
8XSX|1|L5|U|4044
8XSX|1|L5|G|4045
8XSX|1|L5|A|4046
8XSX|1|L5|A|4047
8XSX|1|L5|A|4048
8XSX|1|L5|U|4049
8XSX|1|L5|A|4050
8XSX|1|L5|C|4051
8XSX|1|L5|C|4052
8XSX|1|L5|A|4053
8XSX|1|L5|C|4054
8XSX|1|L5|U|4055
8XSX|1|L5|A|4056
8XSX|1|L5|C|4057
8XSX|1|L5|U|4058
8XSX|1|L5|C|4059
8XSX|1|L5|U|4060
8XSX|1|L5|G|4061
8XSX|1|L5|A|4062
8XSX|1|L5|G|4007
8XSX|1|L5|C|4008
8XSX|1|L5|C|4009
8XSX|1|L5|C|4010
8XSX|1|L5|G|4011
8XSX|1|L5|G|4012
8XSX|1|L5|G|4013
8XSX|1|L5|G|4014
8XSX|1|L5|C|4015
8XSX|1|L5|G|4016
8XSX|1|L5|G|4017
8XSX|1|L5|G|4018
8XSX|1|L5|G|4019
8XSX|1|L5|U|4020
8XSX|1|L5|C|4021
8XSX|1|L5|C|4022
8XSX|1|L5|G|4023
8XSX|1|L5|C|4024
8XSX|1|L5|C|4025
8XSX|1|L5|G|4026
8XSX|1|L5|G|4027
8XSX|1|L5|C|4028
8XSX|1|L5|C|4029
8XSX|1|L5|C|4030
8XSX|1|L5|U|4031
8XSX|1|L5|G|4032
8XSX|1|L5|C|4033
8XSX|1|L5|G|4034
8XSX|1|L5|G|4035
8XSX|1|L5|G|4036
8XSX|1|L5|C|4037
8XSX|1|L5|C|4038
8XSX|1|L5|G|4039
8XSX|1|L5|C|4040
8XSX|1|L5|C|4041
8XSX|1|L5|G|4042
8XSX|1|L5|G|4043
8XSX|1|L5|U|4044
8XSX|1|L5|G|4045
8XSX|1|L5|A|4046
8XSX|1|L5|A|4047
8XSX|1|L5|A|4048
8XSX|1|L5|U|4049
8XSX|1|L5|A|4050
8XSX|1|L5|C|4051
8XSX|1|L5|C|4052
8XSX|1|L5|A|4053
8XSX|1|L5|C|4054
8XSX|1|L5|U|4055
8XSX|1|L5|A|4056
8XSX|1|L5|C|4057
8XSX|1|L5|U|4058
8XSX|1|L5|C|4059
8XSX|1|L5|U|4060
8XSX|1|L5|G|4061
*
8XSX|1|L5|A|4062

Current chains

Chain L5

28S rRNA

Nearby chains

Chain CC

Transfer RNA; tRNA

Chain Lz

60S ribosomal protein L10a