IL_10PX_245

3D structure

PDB id

10PX (explore in PDB, NAKB, or RNA 3D Hub)

Description

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with benzoxaborole derivative of azithromycin (AZI-BB2), mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution

Experimental method

X-RAY DIFFRACTION

Resolution

2.45 Å

Loop

Sequence

CGAAA(5MU)UC(5MC)UUG*C(5MC)UG

Length

16 nucleotides

Bulged bases

10PX|1|2A|A|1938, 10PX|1|2A|U|1944, 10PX|1|2A|U|1963

QA status

Modified nucleotides: 5MU, 5MC

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

IL_10PX_245 not in the Motif Atlas

Homologous match to IL_7A0S_072

Geometric discrepancy: 0.2531

The information below is about IL_7A0S_072

Detailed Annotation

No text annotation

Broad Annotation

No text annotation

Motif group

IL_04332.3

Basepair signature

cWW-L-R-L-cWW-L-L-R-L-R-L

Number of instances in this motif group

2

Unit IDs

10PX|1|2A|C|1934
10PX|1|2A|G|1935
10PX|1|2A|A|1936
10PX|1|2A|A|1937
10PX|1|2A|A|1938
10PX|1|2A|5MU|1939
10PX|1|2A|U|1940
10PX|1|2A|C|1941
10PX|1|2A|5MC|1942
10PX|1|2A|U|1943
10PX|1|2A|U|1944
10PX|1|2A|G|1945
*
10PX|1|2A|C|1961
10PX|1|2A|5MC|1962
10PX|1|2A|U|1963
10PX|1|2A|G|1964

Current chains

Chain 2A

23S Ribosomal RNA

Nearby chains

Chain 2D

50S ribosomal protein L2

Chain 2a

Small subunit ribosomal RNA; SSU rRNA

Chain 2w

Transfer RNA; tRNA

Chain 2x

Transfer RNA; tRNA