IL_2L8C_001

3D structure

PDB id

2L8C (explore in PDB, NAKB, or RNA 3D Hub)

Description

NMR Spectroscopy and Molecular Dynamics Simulation of r(CCGCUGCGG)2 Reveal a Dynamic UU Internal Loop Found in Myotonic Dystrophy Type 1 - UU pair with zero hydrogen bond pairs

Experimental method

SOLUTION NMR

Resolution

Loop

Sequence

CUG*CUG

Length

6 nucleotides

Bulged bases

None detected

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

IL_2L8C_001 not in the Motif Atlas

Geometric match to IL_5MWI_003

Geometric discrepancy: 0.1232

The information below is about IL_5MWI_003

Detailed Annotation

Isolated non-canonical cWW pair

Broad Annotation

No text annotation

Motif group

IL_87907.2

Basepair signature

cWW-cWW-cWW

Number of instances in this motif group

179

Unit IDs

2L8C|1|A|C|4
2L8C|1|A|U|5
2L8C|1|A|G|6
*
2L8C|1|B|C|13
2L8C|1|B|U|14
2L8C|1|B|G|15

Current chains

Chain A

RNA (5'-R(*CP*CP*GP*CP*UP*GP*CP*GP*G)-3')

Chain B

RNA (5'-R(*CP*CP*GP*CP*UP*GP*CP*GP*G)-3')

Nearby chains