IL_4PCJ_002

3D structure

PDB id

4PCJ (explore in PDB, NAKB, or RNA 3D Hub)

Description

Modifications to toxic CUG RNAs induce structural stability and rescue mis-splicing in Myotonic Dystrophy

Experimental method

X-RAY DIFFRACTION

Resolution

1.9 Å

Loop

Sequence

C(PSU)G*CUG

Length

6 nucleotides

Bulged bases

None detected

QA status

Modified nucleotides: PSU

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

Detailed Annotation

Isolated non-canonical cWW pair

Broad Annotation

No text annotation

Motif group

IL_42997.3

Basepair signature

cWW-L-R-cWW

Number of instances in this motif group

20

Unit IDs

4PCJ|1|A|C|4
4PCJ|1|A|PSU|5
4PCJ|1|A|G|6
*
4PCJ|1|A|C|30
4PCJ|1|A|U|31
4PCJ|1|A|G|32

Current chains

Chain A

trCUG-3('5)

Nearby chains