IL_5NFV_002

3D structure

PDB id

5NFV (explore in PDB, NAKB, or RNA 3D Hub)

Description

Crystal structure of catalytically inactive FnCas12 mutant bound to an R-loop structure containing a pre-crRNA mimic and full-length DNA target

Experimental method

X-RAY DIFFRACTION

Resolution

2.5 Å

Loop

Sequence

UAAAAG*CTTTTA

Length

12 nucleotides

Bulged bases

None detected

QA status

Self-complementary:

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

Detailed Annotation

No text annotation

Broad Annotation

No text annotation

Motif group

Not in a motif group

Basepair signature

Not available

Number of instances in this motif group

0

Unit IDs

5NFV|1|B|U|5
5NFV|1|B|A|6
5NFV|1|B|A|7
5NFV|1|B|A|8
5NFV|1|B|A|9
5NFV|1|B|G|10
*
5NFV|1|C|DC|-10
5NFV|1|C|DT|-9
5NFV|1|C|DT|-8
5NFV|1|C|DT|-7
5NFV|1|C|DT|-6
5NFV|1|C|DA|-5

Current chains

Chain B

pre-crRNA

Chain C

DNA target strand

Nearby chains

Chain A

CRISPR-associated endonuclease Cpf1