IL_7QQQ_002

3D structure

PDB id

7QQQ (explore in PDB, NAKB, or RNA 3D Hub)

Description

SpCas9 bound to AAVS1 off-target4 DNA substrate

Experimental method

X-RAY DIFFRACTION

Resolution

2.65 Å

Loop

Sequence

GC*GUC

Length

5 nucleotides

Bulged bases

7QQQ|1|A|U|59

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

IL_7QQQ_002 not in the Motif Atlas

Geometric match to IL_7ZO1_002

Geometric discrepancy: 0.0337

The information below is about IL_7ZO1_002

Detailed Annotation

Single bulged U

Broad Annotation

No text annotation

Motif group

IL_89505.4

Basepair signature

cWW-L-cWW

Number of instances in this motif group

117

Unit IDs

7QQQ|1|A|G|54
7QQQ|1|A|C|55
*
7QQQ|1|A|G|58
7QQQ|1|A|U|59
7QQQ|1|A|C|60

Current chains

Chain A

AAVS1 sgRNA

Nearby chains

Chain B

CRISPR-associated endonuclease Cas9/Csn1