J4_6CAE_033

3D structure

PDB id

6CAE (explore in PDB, NAKB, or RNA 3D Hub)

Description

Crystal structure of the Thermus thermophilus 70S ribosome in complex with NOSO-95179 antibiotic and bound to mRNA and A-, P- and E-site tRNAs at 2.6A resolution

Experimental method

X-RAY DIFFRACTION

Resolution

2.6 Å

Loop

Sequence

U(4SU)AG*CAC*GGG(7MG)UCG*CA

Length

16 nucleotides

Bulged bases

6CAE|1|2w|4SU|8, 6CAE|1|2w|U|47, 6CAE|1|2w|C|48

QA status

Modified nucleotides: 4SU, 7MG

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

J4_6CAE_033 not in the Motif Atlas

Homologous match to J4_6UGG_002

Geometric discrepancy: 0.2577

The information below is about J4_6UGG_002

Detailed Annotation

No text annotation

Broad Annotation

No text annotation

Motif group

J4_70449.29

Basepair signature

cWW-F-cWW-cWW-cHS-F-cWW-cWW

Number of instances in this motif group

54

Unit IDs

6CAE|1|2w|U|7
6CAE|1|2w|4SU|8
6CAE|1|2w|A|9
6CAE|1|2w|G|10
*
6CAE|1|2w|C|25
6CAE|1|2w|A|26
6CAE|1|2w|C|27
*
6CAE|1|2w|G|43
6CAE|1|2w|G|44
6CAE|1|2w|G|45
6CAE|1|2w|7MG|46
6CAE|1|2w|U|47
6CAE|1|2w|C|48
6CAE|1|2w|G|49
*
6CAE|1|2w|C|65
6CAE|1|2w|A|66

Current chains

Chain 2w

A-site and E-site tRNAs

Nearby chains

Chain 2A

Large subunit ribosomal RNA; LSU rRNA