J5_10PX_011

3D structure

PDB id

10PX (explore in PDB, NAKB, or RNA 3D Hub)

Description

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with benzoxaborole derivative of azithromycin (AZI-BB2), mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution

Experimental method

X-RAY DIFFRACTION

Resolution

2.45 Å

Loop

Sequence

CUAAAC*GGGUCGUG*CGAGUAC*GGAAUCUG*UAAG

Length

33 nucleotides

Bulged bases

10PX|1|2A|C|271|||Z, 10PX|1|2A|U|272|||A, 10PX|1|2A|U|405

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

Detailed Annotation

No text annotation

Broad Annotation

No text annotation

Motif group

Not in a motif group

Basepair signature

Not available

Number of instances in this motif group

0

Unit IDs

10PX|1|2A|C|268
10PX|1|2A|U|269
10PX|1|2A|A|270
10PX|1|2A|A|271
10PX|1|2A|A|271|||A
10PX|1|2A|C|271|||B
*
10PX|1|2A|G|271|||V
10PX|1|2A|G|271|||W
10PX|1|2A|G|271|||X
10PX|1|2A|U|271|||Y
10PX|1|2A|C|271|||Z
10PX|1|2A|G|272
10PX|1|2A|U|272|||A
10PX|1|2A|G|272|||B
*
10PX|1|2A|C|366
10PX|1|2A|G|370
10PX|1|2A|A|371
10PX|1|2A|G|372
10PX|1|2A|U|373
10PX|1|2A|A|374
10PX|1|2A|C|375
*
10PX|1|2A|G|399
10PX|1|2A|G|400
10PX|1|2A|A|401
10PX|1|2A|A|402
10PX|1|2A|U|403
10PX|1|2A|C|404
10PX|1|2A|U|405
10PX|1|2A|G|406
*
10PX|1|2A|U|421
10PX|1|2A|A|422
10PX|1|2A|A|423
10PX|1|2A|G|424

Current chains

Chain 2A

23S Ribosomal RNA

Nearby chains

Chain 21

50S ribosomal protein L28

Chain 2I

50S ribosomal protein L9