3D structure

PDB id
10PX (explore in PDB, NAKB, or RNA 3D Hub)
Description
Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with benzoxaborole derivative of azithromycin (AZI-BB2), mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution
Experimental method
X-RAY DIFFRACTION
Resolution
2.45 Å

Loop

Sequence
AAAAGACC*GGAUAACA*UCG(2MA)UGUC*GGUUCAG*CGGUCU
Length
37 nucleotides
Bulged bases
10PX|1|2A|A|2448, 10PX|1|2A|U|2449, 10PX|1|2A|U|2609
QA status
Modified nucleotides: 2MA

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.
R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.
R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.
R3DMCS Rfam
Detailed Annotation
No text annotation
Broad Annotation
No text annotation
Motif group
Not in a motif group
Basepair signature
Not available
Number of instances in this motif group
0

Unit IDs

10PX|1|2A|A|2057
10PX|1|2A|A|2058
10PX|1|2A|A|2059
10PX|1|2A|A|2060
10PX|1|2A|G|2061
10PX|1|2A|A|2062
10PX|1|2A|C|2063
10PX|1|2A|C|2064
*
10PX|1|2A|G|2446
10PX|1|2A|G|2447
10PX|1|2A|A|2448
10PX|1|2A|U|2449
10PX|1|2A|A|2450
10PX|1|2A|A|2451
10PX|1|2A|C|2452
10PX|1|2A|A|2453
*
10PX|1|2A|U|2500
10PX|1|2A|C|2501
10PX|1|2A|G|2502
10PX|1|2A|2MA|2503
10PX|1|2A|U|2504
10PX|1|2A|G|2505
10PX|1|2A|U|2506
10PX|1|2A|C|2507
*
10PX|1|2A|G|2582
10PX|1|2A|G|2583
10PX|1|2A|U|2584
10PX|1|2A|U|2585
10PX|1|2A|C|2586
10PX|1|2A|A|2587
10PX|1|2A|G|2588
*
10PX|1|2A|C|2606
10PX|1|2A|G|2607
10PX|1|2A|G|2608
10PX|1|2A|U|2609
10PX|1|2A|C|2610
10PX|1|2A|U|2611

Current chains

Chain 2A
23S Ribosomal RNA

Nearby chains

Chain 20
50S ribosomal protein L27
Chain 25
50S ribosomal protein L32
Chain 2D
50S ribosomal protein L2
Chain 2E
50S ribosomal protein L3
Chain 2F
50S ribosomal protein L4
Chain 2P
50S ribosomal protein L15
Chain 2Q
50S ribosomal protein L16
Chain 2w
Transfer RNA; tRNA
Chain 2x
Transfer RNA; tRNA

Coloring options:

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