J5_4U4Q_009

3D structure

PDB id

4U4Q (explore in PDB, NAKB, or RNA 3D Hub)

Description

Crystal structure of Homoharringtonine bound to the yeast 80S ribosome

Experimental method

X-RAY DIFFRACTION

Resolution

3 Å

Loop

Sequence

AUAGUUCCUUUACUACAUGG*CAUGCUUAAAA*UG*CGA*UGGUU

Length

41 nucleotides

Bulged bases

4U4Q|1|2|U|128, 4U4Q|1|2|U|132, 4U4Q|1|2|C|136, 4U4Q|1|2|U|137, 4U4Q|1|2|A|140, 4U4Q|1|2|U|141, 4U4Q|1|2|U|178

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

Detailed Annotation

No text annotation

Broad Annotation

No text annotation

Motif group

Not in a motif group

Basepair signature

Not available

Number of instances in this motif group

0

Unit IDs

4U4Q|1|2|A|124
4U4Q|1|2|U|125
4U4Q|1|2|A|126
4U4Q|1|2|G|127
4U4Q|1|2|U|128
4U4Q|1|2|U|129
4U4Q|1|2|C|130
4U4Q|1|2|C|131
4U4Q|1|2|U|132
4U4Q|1|2|U|133
4U4Q|1|2|U|134
4U4Q|1|2|A|135
4U4Q|1|2|C|136
4U4Q|1|2|U|137
4U4Q|1|2|A|138
4U4Q|1|2|C|139
4U4Q|1|2|A|140
4U4Q|1|2|U|141
4U4Q|1|2|G|142
4U4Q|1|2|G|143
*
4U4Q|1|2|C|172
4U4Q|1|2|A|173
4U4Q|1|2|U|174
4U4Q|1|2|G|175
4U4Q|1|2|C|176
4U4Q|1|2|U|177
4U4Q|1|2|U|178
4U4Q|1|2|A|179
4U4Q|1|2|A|180
4U4Q|1|2|A|181
4U4Q|1|2|A|182
*
4U4Q|1|2|U|203
4U4Q|1|2|G|204
*
4U4Q|1|2|C|263
4U4Q|1|2|G|264
4U4Q|1|2|A|265
*
4U4Q|1|2|U|289
4U4Q|1|2|G|290
4U4Q|1|2|G|291
4U4Q|1|2|U|292
4U4Q|1|2|U|293

Current chains

Chain 2

18S ribosomal RNA

Nearby chains

Chain S4

40S ribosomal protein S4-A

Chain S6

40S ribosomal protein S6-A

Chain S8

40S ribosomal protein S8-A