J5_7TOP_004

3D structure

PDB id

7TOP (explore in PDB, NAKB, or RNA 3D Hub)

Description

Yeast 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein PR20

Experimental method

ELECTRON MICROSCOPY

Resolution

2.4 Å

Loop

Sequence

GCAAAAUAG*UG*UG*CGGACAAGG*CAC

Length

25 nucleotides

Bulged bases

7TOP|1|A25S|G|2116, 7TOP|1|A25S|G|2121

QA status

Valid loop

Sequence variability

If this chain is mapped to an Rfam alignment, the link below will give its sequence variability.

R3DSVS

Structural variability across Equivalence Class

The link below will give the loop's structural variability across the equivalence class for this chain.

R3DMCS EC

Structural variability across Rfam

If this chain is mapped to an Rfam alignment, the link below will give the loop's structural variability between chains mapped to the same Rfam family.

R3DMCS Rfam

J5_7TOP_004 not in the Motif Atlas

Homologous match to J5_8P9A_013

Geometric discrepancy: 0.0747

The information below is about J5_8P9A_013

Detailed Annotation

No text annotation

Broad Annotation

No text annotation

Motif group

J5_62523.6

Basepair signature

cWW-F-F-F-cWW-F-F-F-F-F-F-F-F-F-cWW-F-cWW-cWW

Number of instances in this motif group

7

Unit IDs

7TOP|1|A25S|G|1906
7TOP|1|A25S|C|1907
7TOP|1|A25S|A|1908
7TOP|1|A25S|A|1909
7TOP|1|A25S|A|1910
7TOP|1|A25S|A|1911
7TOP|1|A25S|U|1912
7TOP|1|A25S|A|1913
7TOP|1|A25S|G|1914
*
7TOP|1|A25S|U|1938
7TOP|1|A25S|G|1939
*
7TOP|1|A25S|U|2109
7TOP|1|A25S|G|2110
*
7TOP|1|A25S|C|2114
7TOP|1|A25S|G|2115
7TOP|1|A25S|G|2116
7TOP|1|A25S|A|2117
7TOP|1|A25S|C|2118
7TOP|1|A25S|A|2119
7TOP|1|A25S|A|2120
7TOP|1|A25S|G|2121
7TOP|1|A25S|G|2122
*
7TOP|1|A25S|C|2331
7TOP|1|A25S|A|2332
7TOP|1|A25S|C|2333

Current chains

Chain A25S

25S rRNA

Nearby chains

Chain AL03

RPL3 isoform 1

Chain AL19

60S ribosomal protein L19-A

Chain AL23

60S ribosomal protein L23-A

Chain AL24

RPL24A isoform 1