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Equivalence class NR_2.5_65061.40 Obsolete

#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. Å#NTsDate
18QYX|1|A2+ 8QYX|1|C2 (rep)Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human 60S ribosomal subunitElectron microscopy1.7838622024-12-11
28GLP|1|L5+ 8GLP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)Electron microscopy1.6737022023-04-19
38QOI|1|L5+ 8QOI|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA (3773-MER), 5.8S rRNA (156-MER)Homo sapiensEukaryaRF02543 + RF00002Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNAElectron microscopy1.939292024-06-12
48YOO|1|L5+ 8YOO|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human 80S ribosome with 100 um TigecyclineElectron microscopy238262024-07-10
58A3D|1|A+ 8A3D|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human mature large subunit of the ribosome with eIF6 and homoharringtonine boundElectron microscopy1.6734512023-03-08
68YOP|1|L5+ 8YOP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human 80S ribosome with 4 um TigecyclineElectron microscopy2.239272024-07-10
79AZC|1|L5+ 9AZC|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human 80S ribosome (Consensus map)Electron microscopy2.1938962025-04-30
89C3H|1|L5+ 9C3H|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Structure of the CNOT3-bound human 80S ribosome with tRNA-ARG in the P-site.Electron microscopy236792024-12-04
98G5Y|1|L5+ 8G5Y|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)Electron microscopy2.2938772023-04-19
108XSX|1|L5+ 8XSX|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2Electron microscopy2.439272024-07-10
118K2C|1|L5+ 8K2C|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human 80S ribosome with TigecyclineElectron microscopy2.439272024-07-10
128JDK|1|D+ 8JDK|1|FLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)Electron microscopy2.2636682023-12-06
137XNY|1|L1+ 7XNY|1|L3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsElectron microscopy2.539292023-04-05
147OW7|1|A+ 7OW7|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002EIF6-bound large subunit of the human ribosomeElectron microscopy2.234512022-10-05
158JDL|1|D+ 8JDL|1|FLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state)Electron microscopy2.4236682023-12-06
168JDJ|1|D+ 8JDJ|1|FLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU)Electron microscopy2.536682023-12-06
178QFD|1|5+ 8QFD|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002UFL1 E3 ligase bound 60S ribosomeElectron microscopy2.232742024-02-21
188FLE|1|L3+ 8FLE|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State L2)Electron microscopy2.4835262023-07-12
198FKW|1|L3+ 8FKW|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State D2)Electron microscopy2.524292023-07-12
208FKV|1|L3+ 8FKV|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State D1)Electron microscopy2.4723652023-07-12

Release history

Release3.3853.386
Date2025-04-302025-05-07

Parents

This classParent classesRelease idIntersectionAdded to this classOnly in parent

Children

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Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.

#SViewPDBTitleMethodResolution#NTs
18QYX|1|A2+ 8QYX|1|C2Human 60S ribosomal subunitELECTRON MICROSCOPY1.783862
27OW7|1|A+ 7OW7|1|CEIF6-bound large subunit of the human ribosomeELECTRON MICROSCOPY2.23451
38A3D|1|A+ 8A3D|1|CHuman mature large subunit of the ribosome with eIF6 and homoharringtonine boundELECTRON MICROSCOPY1.673451
48G5Y|1|L5+ 8G5Y|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)ELECTRON MICROSCOPY2.293877
58GLP|1|L5+ 8GLP|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)ELECTRON MICROSCOPY1.673702
68QOI|1|L5+ 8QOI|1|L8Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNAELECTRON MICROSCOPY1.93929
79AZC|1|L5+ 9AZC|1|L8In situ human 80S ribosome (Consensus map)ELECTRON MICROSCOPY2.193896
88XSX|1|L5+ 8XSX|1|L8Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2ELECTRON MICROSCOPY2.43927
99C3H|1|L5+ 9C3H|1|L1Structure of the CNOT3-bound human 80S ribosome with tRNA-ARG in the P-site.ELECTRON MICROSCOPY23679
108YOO|1|L5+ 8YOO|1|L8Cryo-EM structure of the human 80S ribosome with 100 um TigecyclineELECTRON MICROSCOPY23826
118K2C|1|L5+ 8K2C|1|L8Cryo-EM structure of the human 80S ribosome with TigecyclineELECTRON MICROSCOPY2.43927
128YOP|1|L5+ 8YOP|1|L8Cryo-EM structure of the human 80S ribosome with 4 um TigecyclineELECTRON MICROSCOPY2.23927
137XNY|1|L1+ 7XNY|1|L3High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsELECTRON MICROSCOPY2.53929
148JDJ|1|D+ 8JDJ|1|FStructure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU)ELECTRON MICROSCOPY2.53668
158JDK|1|D+ 8JDK|1|FStructure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)ELECTRON MICROSCOPY2.263668
168JDL|1|D+ 8JDL|1|FStructure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state)ELECTRON MICROSCOPY2.423668
178QFD|1|5+ 8QFD|1|8UFL1 E3 ligase bound 60S ribosomeELECTRON MICROSCOPY2.23274
188FLE|1|L3+ 8FLE|1|L1Human nuclear pre-60S ribosomal subunit (State L2)ELECTRON MICROSCOPY2.483526
198FKW|1|L3+ 8FKW|1|L1Human nucleolar pre-60S ribosomal subunit (State D2)ELECTRON MICROSCOPY2.52429
208FKV|1|L3+ 8FKV|1|L1Human nucleolar pre-60S ribosomal subunit (State D1)ELECTRON MICROSCOPY2.472365

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


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