#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. Å#NTsDate
18GLP|1|L5+ 8GLP|1|L8 (rep)Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)Electron microscopy1.6737022023-04-19
29TV2|1|L5+ 9TV2|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF0000280S ribosomes from primary B-cells infected with delta v-snoRNA1 EBVElectron microscopy2.132122026-07-01
39TT7|1|L5+ 9TT7|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF0000280S ribosome of WT EBV infected human B-cellsElectron microscopy2.232112026-07-22
49O3W|1|L5+ 9O3W|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human 80S ribosome bound to IDB-001 stalled on MYC nascent chainElectron microscopy1.937022026-03-04
58QYX|1|A2+ 8QYX|1|C2Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human 60S ribosomal subunitElectron microscopy1.7838622024-12-11
68YOO|1|L5+ 8YOO|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human 80S ribosome with 100 um TigecyclineElectron microscopy238262024-07-10
78QFD|1|5+ 8QFD|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002UFL1 E3 ligase bound 60S ribosomeElectron microscopy2.232742024-02-21
89SPI|1|L5+ 9SPI|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING URIDINEElectron microscopy2.435622026-01-21
99C3H|1|L5+ 9C3H|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Structure of the CNOT3-bound human 80S ribosome with tRNA-ARG in the P-site.Electron microscopy236792024-12-04
108A3D|1|A+ 8A3D|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human mature large subunit of the ribosome with eIF6 and homoharringtonine boundElectron microscopy1.6734512023-03-08
119SPF|1|L5+ 9SPF|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING N1-METHYLPSEUDOURIDINEElectron microscopy2.436222026-01-21
129O3V|1|L5+ 9O3V|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human 80S ribosome stalled on MYC nascent chainElectron microscopy2.237022026-03-04
139S3D|1|L5+ 9S3D|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002NAC bound human RNC with 58 amino acid ARF1-linkerElectron microscopy2.3238042026-02-18
149I2D|1|L5+ 9I2D|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002NMT1-NAC bound human RNC with 10 amino acid ARF1-linkerElectron microscopy2.1938042026-02-04
159S3B|1|L5+ 9S3B|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002NMT1-NAC bound human RNC with 58 amino acid ARF1-linker - State 1Electron microscopy2.3838042026-02-18
169S3C|1|L5+ 9S3C|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002NMT1-NAC bound human RNC with 58 amino acid ARF1-linker - State 2Electron microscopy2.4238042026-02-18
179QLO|1|L5+ 9QLO|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002NMT1-NAC bound human RNC with full length ARF1 - State 1Electron microscopy2.4738042026-02-18
189PBE|1|L5+ 9PBE|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNA [Homo sapiens]Homo sapiensEukaryaRF02543 + RF00002In situ human 80S ribosome (composite map)Electron microscopy2.1938112025-12-24
198G5Y|1|L5+ 8G5Y|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)Electron microscopy2.2938772023-04-19
209RUC|1|L5+ 9RUC|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002WT-HEK 80S ribosome bound to H2B mRNA (WT-H2B)Electron microscopy2.533422026-05-13
219PKD|1|L5+ 9PKD|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ CHX and HHT treated 80S consensus ribosomeElectron microscopy2.4238112026-07-15
228YOP|1|L5+ 8YOP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human 80S ribosome with 4 um TigecyclineElectron microscopy2.239272024-07-10
239O3Y|1|L5+ 9O3Y|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human 80S ribosome bound to IDB-002 stalled on FPAK-containing nascent chainElectron microscopy2.237022026-03-04
248QOI|1|L5+ 8QOI|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA (3773-MER), 5.8S rRNA (156-MER)Homo sapiensEukaryaRF02543 + RF00002Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNAElectron microscopy1.939292024-06-12
259P8B|1|L5+ 9P8B|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human eEF1A-A/T-P-E state 80S ribosomeElectron microscopy2.4838112025-12-24
268JDK|1|D+ 8JDK|1|FLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)Electron microscopy2.2636682023-12-06
279RPV|1|M5+ 9RPV|1|M8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA of the stalled 80S, 5.8S rRNA of the stalled 80SHomo sapiensEukaryaRF02543 + RF00002Structure of the ZAK-bound human disomeElectron microscopy2.3537022025-12-10
289GUL|1|L5+ 9GUL|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Structure of FLuc-XBP1u+ stalled human 60S ribosome nascent chain complexElectron microscopy2.238232025-09-24
2929IW|1|DA+ 29IW|1|DCLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human monosomes with bound toxin NT-2, focus on 60S subunit. Cells treated with NT-2.Electron microscopy1.7736392026-09-30
308XSX|1|L5+ 8XSX|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2Electron microscopy2.439272024-07-10
318JDL|1|D+ 8JDL|1|FLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state)Electron microscopy2.4236682023-12-06
328JDJ|1|D+ 8JDJ|1|FLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU)Electron microscopy2.536682023-12-06
338K2C|1|L5+ 8K2C|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human 80S ribosome with TigecyclineElectron microscopy2.439272024-07-10
349RPV|1|L5+ 9RPV|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA of the collided 80S, 5.8S rRNA of the collided 80SHomo sapiensEukaryaRF02543 + RF00002Structure of the ZAK-bound human disomeElectron microscopy2.3537392025-12-10
3529IX|1|DA+ 29IX|1|DCLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human monosomes with bound toxin NT-2, focus on 60S subunit. NT-2 added to purified ribosomes as control.Electron microscopy2.236392026-09-30
367XNY|1|L1+ 7XNY|1|L3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsElectron microscopy2.539292023-04-05
378FLE|1|L3+ 8FLE|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State L2)Electron microscopy2.4835262023-07-12
389MNC|1|L5+ 9MNC|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human 80S ribosome bound to small molecule SW393071Electron microscopy2.3336562026-06-24
397OW7|1|A+ 7OW7|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002EIF6-bound large subunit of the human ribosomeElectron microscopy2.234512022-10-05
4029IZ|1|BA+ 29IZ|1|BCLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Dormant 80S:eEF2:SERBP1:tRNA complex from human cells treated with toxin NT-2Electron microscopy2.0835892026-09-30
419WW4|1|AA+ 9WW4|1|ACLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA (3773-MER), 5.8S rRNA (156-MER)Homo sapiensEukaryaRF02543 + RF00002human 80S ribosome non-rotated stateElectron microscopy2.4839292026-09-16
428FKV|1|L3+ 8FKV|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State D1)Electron microscopy2.4723652023-07-12
438FKW|1|L3+ 8FKW|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State D2)Electron microscopy2.524292023-07-12
4429IY|1|CA+ 29IY|1|CCLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human monosomes, focus on 60S subunit; control.Electron microscopy2.3636392026-09-30

Release history

Release4.59
Date2026-09-30

Parents

This classParent classesRelease idIntersectionAdded to this classOnly in parent

Children

This class Descendant classesRelease idIntersectionOnly in this classAdded to child

Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.

#SViewPDBTitleMethodResolution#NTs
19TT7|1|L5+ 9TT7|1|L880S ribosome of WT EBV infected human B-cellsELECTRON MICROSCOPY2.23211
29TV2|1|L5+ 9TV2|1|L880S ribosomes from primary B-cells infected with delta v-snoRNA1 EBVELECTRON MICROSCOPY2.13212
39RUC|1|L5+ 9RUC|1|L8WT-HEK 80S ribosome bound to H2B mRNA (WT-H2B)ELECTRON MICROSCOPY2.53342
48G5Y|1|L5+ 8G5Y|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)ELECTRON MICROSCOPY2.293877
58GLP|1|L5+ 8GLP|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)ELECTRON MICROSCOPY1.673702
69O3W|1|L5+ 9O3W|1|L8Human 80S ribosome bound to IDB-001 stalled on MYC nascent chainELECTRON MICROSCOPY1.93702
79O3Y|1|L5+ 9O3Y|1|L8Human 80S ribosome bound to IDB-002 stalled on FPAK-containing nascent chainELECTRON MICROSCOPY2.23702
89O3V|1|L5+ 9O3V|1|L8Human 80S ribosome stalled on MYC nascent chainELECTRON MICROSCOPY2.23702
99SPF|1|L5+ 9SPF|1|L8CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING N1-METHYLPSEUDOURIDINEELECTRON MICROSCOPY2.43622
109SPI|1|L5+ 9SPI|1|L8CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING URIDINEELECTRON MICROSCOPY2.43562
119RPV|1|M5+ 9RPV|1|M8Structure of the ZAK-bound human disomeELECTRON MICROSCOPY2.353702
127OW7|1|A+ 7OW7|1|CEIF6-bound large subunit of the human ribosomeELECTRON MICROSCOPY2.23451
138A3D|1|A+ 8A3D|1|CHuman mature large subunit of the ribosome with eIF6 and homoharringtonine boundELECTRON MICROSCOPY1.673451
148XSX|1|L5+ 8XSX|1|L8Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2ELECTRON MICROSCOPY2.43927
159PBE|1|L5+ 9PBE|1|L8In situ human 80S ribosome (composite map)ELECTRON MICROSCOPY2.193811
169P8B|1|L5+ 9P8B|1|L8In situ human eEF1A-A/T-P-E state 80S ribosomeELECTRON MICROSCOPY2.483811
179PKD|1|L5+ 9PKD|1|L8In situ CHX and HHT treated 80S consensus ribosomeELECTRON MICROSCOPY2.423811
189I2D|1|L5+ 9I2D|1|L8NMT1-NAC bound human RNC with 10 amino acid ARF1-linkerELECTRON MICROSCOPY2.193804
199S3B|1|L5+ 9S3B|1|L8NMT1-NAC bound human RNC with 58 amino acid ARF1-linker - State 1ELECTRON MICROSCOPY2.383804
209S3C|1|L5+ 9S3C|1|L8NMT1-NAC bound human RNC with 58 amino acid ARF1-linker - State 2ELECTRON MICROSCOPY2.423804
219S3D|1|L5+ 9S3D|1|L8NAC bound human RNC with 58 amino acid ARF1-linkerELECTRON MICROSCOPY2.323804
229QLO|1|L5+ 9QLO|1|L8NMT1-NAC bound human RNC with full length ARF1 - State 1ELECTRON MICROSCOPY2.473804
239C3H|1|L5+ 9C3H|1|L1Structure of the CNOT3-bound human 80S ribosome with tRNA-ARG in the P-site.ELECTRON MICROSCOPY23679
249MNC|1|L5+ 9MNC|1|L1Human 80S ribosome bound to small molecule SW393071ELECTRON MICROSCOPY2.333656
257XNY|1|L1+ 7XNY|1|L3High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsELECTRON MICROSCOPY2.53929
268YOP|1|L5+ 8YOP|1|L8Cryo-EM structure of the human 80S ribosome with 4 um TigecyclineELECTRON MICROSCOPY2.23927
278K2C|1|L5+ 8K2C|1|L8Cryo-EM structure of the human 80S ribosome with TigecyclineELECTRON MICROSCOPY2.43927
288YOO|1|L5+ 8YOO|1|L8Cryo-EM structure of the human 80S ribosome with 100 um TigecyclineELECTRON MICROSCOPY23826
299WW4|1|AA+ 9WW4|1|AChuman 80S ribosome non-rotated stateELECTRON MICROSCOPY2.483929
308QOI|1|L5+ 8QOI|1|L8Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNAELECTRON MICROSCOPY1.93929
319RPV|1|L5+ 9RPV|1|L8Structure of the ZAK-bound human disomeELECTRON MICROSCOPY2.353739
3229IZ|1|BA+ 29IZ|1|BCDormant 80S:eEF2:SERBP1:tRNA complex from human cells treated with toxin NT-2ELECTRON MICROSCOPY2.083589
338QYX|1|A2+ 8QYX|1|C2Human 60S ribosomal subunitELECTRON MICROSCOPY1.783862
3429IY|1|CA+ 29IY|1|CCHuman monosomes, focus on 60S subunit; control.ELECTRON MICROSCOPY2.363639
3529IX|1|DA+ 29IX|1|DCHuman monosomes with bound toxin NT-2, focus on 60S subunit. NT-2 added to purified ribosomes as control.ELECTRON MICROSCOPY2.23639
3629IW|1|DA+ 29IW|1|DCHuman monosomes with bound toxin NT-2, focus on 60S subunit. Cells treated with NT-2.ELECTRON MICROSCOPY1.773639
378JDK|1|D+ 8JDK|1|FStructure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)ELECTRON MICROSCOPY2.263668
388JDJ|1|D+ 8JDJ|1|FStructure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU)ELECTRON MICROSCOPY2.53668
398JDL|1|D+ 8JDL|1|FStructure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state)ELECTRON MICROSCOPY2.423668
408QFD|1|5+ 8QFD|1|8UFL1 E3 ligase bound 60S ribosomeELECTRON MICROSCOPY2.23274
419GUL|1|L5+ 9GUL|1|L8Structure of FLuc-XBP1u+ stalled human 60S ribosome nascent chain complexELECTRON MICROSCOPY2.23823
428FLE|1|L3+ 8FLE|1|L1Human nuclear pre-60S ribosomal subunit (State L2)ELECTRON MICROSCOPY2.483526
438FKW|1|L3+ 8FKW|1|L1Human nucleolar pre-60S ribosomal subunit (State D2)ELECTRON MICROSCOPY2.52429
448FKV|1|L3+ 8FKV|1|L1Human nucleolar pre-60S ribosomal subunit (State D1)ELECTRON MICROSCOPY2.472365

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


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