Equivalence class NR_20.0_01487.2 Current
| # | IFE | Standardized name | Molecule | Organism | Source | Rfam | Title | Method | Res. Å | #NTs | Date |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 6GKH|1|X+ 6GKH|1|Y (rep) | RNA (5'-R(P*GP*UP*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*A)-3'), RNA (5'-R(P*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*GP*AP*C)-3') | Pseudomonas virus phi6 | CryoEM structure of the MDA5-dsRNA filament in complex with ADP-AlF4 | Electron microscopy | 4.06 | 30 | 2018-11-21 | |||
| 2 | 7NIC|1|X+ 7NIC|1|Y | RNA (5'-R(P*GP*UP*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*A)-3'), RNA (5'-R(P*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*GP*AP*C)-3') | synthetic construct | CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ADP-AlF4(minor class) | Electron microscopy | 4.3 | 30 | 2021-11-17 | |||
| 3 | 9F3P|1|X+ 9F3P|1|Y | RNA (5'-R(P*GP*UP*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*A)-3'), RNA (5'-R(P*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*GP*AP*C)-3') | Mus musculus | Cryo-EM structure of the A946T MDA5-dsRNA filament | Electron microscopy | 3.97 | 30 | 2025-02-26 | |||
| 4 | 9F20|1|X+ 9F20|1|Y | RNA (5'-R(P*GP*UP*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*A)-3'), RNA (5'-R(P*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*GP*AP*C)-3') | Mus musculus | Cryo-EM structure of the I923V MDA5-dsRNA filament with ADP-AlF4 bound and 88-degree helical twist | Electron microscopy | 4.13 | 30 | 2025-02-26 |
Release history
| Release | 4.0 |
|---|---|
| Date | 2025-08-13 |
Parents
| This class | Parent classes | Release id | Intersection | Added to this class | Only in parent |
|---|
Children
| This class | Descendant classes | Release id | Intersection | Only in this class | Added to child |
|---|
Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.
| #S | View | PDB | Title | Method | Resolution | #NTs |
|---|---|---|---|---|---|---|
| 1 | 9F3P|1|X+ 9F3P|1|Y | Cryo-EM structure of the A946T MDA5-dsRNA filament | ELECTRON MICROSCOPY | 3.97 | 30 | |
| 2 | 9F20|1|X+ 9F20|1|Y | Cryo-EM structure of the I923V MDA5-dsRNA filament with ADP-AlF4 bound and 88-degree helical twist | ELECTRON MICROSCOPY | 4.13 | 30 | |
| 3 | 7NIC|1|X+ 7NIC|1|Y | CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ADP-AlF4(minor class) | ELECTRON MICROSCOPY | 4.3 | 30 | |
| 4 | 6GKH|1|X+ 6GKH|1|Y | CryoEM structure of the MDA5-dsRNA filament in complex with ADP-AlF4 | ELECTRON MICROSCOPY | 4.06 | 30 |
Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.
Coloring options: