#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. ÅDate
18H6L|1|4A (rep)U4 spliceosomal RNApre-mRNA, U4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM structure of human exon-defined spliceosome in the early B state.Electron microscopy2.62024-05-01
28H6K|1|4AU4 spliceosomal RNApre-mRNA, U4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM structure of human exon-defined spliceosome in the mature B state.Electron microscopy2.72024-05-01
36QW6|1|4U4 spliceosomal RNAU4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution.Electron microscopy2.922019-04-17
48H6E|1|4AU4 spliceosomal RNApre-mRNA, U4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM structure of human exon-defined spliceosome in the late pre-B state.Electron microscopy3.22024-05-01
58H6J|1|4AU4 spliceosomal RNAU4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state.Electron microscopy3.252024-05-01
68QOZ|1|4U4 spliceosomal RNA5'ss RNA oligo, U4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM Structure of Pre-B+5'ss+ATPgammaS Complex (core part)Electron microscopy3.12024-05-22
78Q7N|1|4U4 spliceosomal RNAU4 snRNAHomo sapiensEukaryaRF00015cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)Electron microscopy3.12024-01-24
86QX9|1|4U4 spliceosomal RNAU4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).Electron microscopy3.282019-04-17
98QPE|1|4U4 spliceosomal RNAoligo1, oligo2, U4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM Structure of Pre-B-like Complex (core part)Electron microscopy3.12024-05-22
108QP8|1|4U4 spliceosomal RNAU4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM Structure of Pre-B Complex (core part)Electron microscopy3.52024-05-22
118QPB|1|4U4 spliceosomal RNA5'ss oligo, U4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM Structure of Pre-B+ATP Complex (core part)Electron microscopy3.72024-05-22
126AHD|1|I+ 6AHD|1|H+ 6AHD|1|FU4 spliceosomal RNA + U2 splicesomal small nuclear RNA + U6 spliceosomal RNApre-mRNA, U2snRNA, U4snRNA, U6snRNAHomo sapiensEukaryaRF00015 + RF00004 + RF00026The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolutionElectron microscopy3.82018-11-14
138QZS|1|4U4 spliceosomal RNAOligo 1, Oligo 2, U4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM structure of the cross-exon B-like complexElectron microscopy4.12024-05-22
148QPA|1|4U4 spliceosomal RNA5'ss oligo, U4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM Structure of Pre-B+5'ssLNG Complex (core part)Electron microscopy3.72024-05-22
158R09|1|4U4 spliceosomal RNA5'ss oligo, U4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complexElectron microscopy4.32024-05-22
168R0B|1|4U4 spliceosomal RNA5'ss oligo, U4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM structure of the cross-exon pre-B+ATP complexElectron microscopy4.42024-05-22
178QP9|1|4U4 spliceosomal RNAU4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM Structure of Pre-B+AMPPNP Complex (core part)Electron microscopy4.12024-05-22
188QPK|1|4U4 spliceosomal RNA5'ss oligo, U4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM Structure of Pre-B+5'ss Complex (core part)Electron microscopy4.22024-05-22
195O9Z|1|4+ 5O9Z|1|2+ 5O9Z|1|6U4 spliceosomal RNA + U2 splicesomal small nuclear RNA + U6 spliceosomal RNAHomo sapiens RNA, U6 small nuclear 1 (RNU6-1), small nuclear RNA, Homo sapiens U4A snRNA, Human gene for small nuclear RNA U2 (snRNA U2), MINX pre-mRNAHomo sapiensEukaryaRF00015 + RF00004 + RF00026Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex)Electron microscopy4.52017-08-16
208QO9|1|4U4 spliceosomal RNAU4 snRNAHomo sapiensEukaryaRF00015Cryo-EM structure of a human spliceosomal B complex protomerElectron microscopy5.292024-01-24
218R0A|1|4U4 spliceosomal RNA5'ss oligo, U4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM structure of the cross-exon pre-B+5'ss complexElectron microscopy5.82024-05-22
226AH0|1|I+ 6AH0|1|H+ 6AH0|1|FU4 spliceosomal RNA + U2 splicesomal small nuclear RNA + U6 spliceosomal RNApre-mRNA, U2snRNA, U4snRNA, U6snRNAHomo sapiensEukaryaRF00015 + RF00004 + RF00026The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex)Electron microscopy5.72018-11-14
238R08|1|4U4 spliceosomal RNAU4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM structure of the cross-exon pre-B+AMPPNP complexElectron microscopy6.12024-05-22
248RM5|1|4U4 spliceosomal RNA5'SS oligo, U4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complexElectron microscopy6.92024-05-22
253JCR|1|MU4 spliceosomal RNAU4 snRNAHomo sapiensEukaryaRF000153D structure determination of the human*U4/U6.U5* tri-snRNP complexElectron microscopy72016-03-09
268QXD|1|4U4 spliceosomal RNAU4 snRNA, U6 snRNAHomo sapiensEukaryaRF00015Cryo-EM structure of the cross-exon pre-B complexElectron microscopy9.62024-05-22

Release history

Release3.3363.3373.3383.3393.3403.3413.3423.3433.3443.3453.3463.3473.3483.3493.3503.3513.3523.3533.3543.3553.3563.3573.3583.3593.3603.3613.362
Date2024-05-222024-05-292024-06-052024-06-122024-06-192024-06-262024-07-032024-07-102024-07-172024-07-252024-07-312024-08-072024-08-142024-08-212024-08-282024-09-042024-09-112024-09-182024-09-252024-10-022024-10-092024-10-162024-10-232024-10-302024-11-062024-11-132024-11-20

Parents

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Children

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Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.

#SViewPDBTitleMethodResolutionLength
18H6L|1|4ACryo-EM structure of human exon-defined spliceosome in the early B state.ELECTRON MICROSCOPY2.6128
28H6K|1|4ACryo-EM structure of human exon-defined spliceosome in the mature B state.ELECTRON MICROSCOPY2.7128
35O9Z|1|4+ 5O9Z|1|2+ 5O9Z|1|6Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex)ELECTRON MICROSCOPY4.5137
46AHD|1|I+ 6AHD|1|H+ 6AHD|1|FThe Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolutionELECTRON MICROSCOPY3.8136
58Q7N|1|4cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)ELECTRON MICROSCOPY3.176
68QO9|1|4Cryo-EM structure of a human spliceosomal B complex protomerELECTRON MICROSCOPY5.29127
78QPE|1|4Cryo-EM Structure of Pre-B-like Complex (core part)ELECTRON MICROSCOPY3.163
88QZS|1|4Cryo-EM structure of the cross-exon B-like complexELECTRON MICROSCOPY4.1136
98QPA|1|4Cryo-EM Structure of Pre-B+5'ssLNG Complex (core part)ELECTRON MICROSCOPY3.762
108RM5|1|4Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complexELECTRON MICROSCOPY6.9110
118QPB|1|4Cryo-EM Structure of Pre-B+ATP Complex (core part)ELECTRON MICROSCOPY3.780
128R0B|1|4Cryo-EM structure of the cross-exon pre-B+ATP complexELECTRON MICROSCOPY4.4128
138R09|1|4Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complexELECTRON MICROSCOPY4.3128
148QOZ|1|4Cryo-EM Structure of Pre-B+5'ss+ATPgammaS Complex (core part)ELECTRON MICROSCOPY3.180
156AH0|1|I+ 6AH0|1|H+ 6AH0|1|FThe Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex)ELECTRON MICROSCOPY5.7117
168H6E|1|4ACryo-EM structure of human exon-defined spliceosome in the late pre-B state.ELECTRON MICROSCOPY3.2125
178H6J|1|4ACryo-EM structure of human exon-defined spliceosome in the mature pre-B state.ELECTRON MICROSCOPY3.25125
186QX9|1|4Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).ELECTRON MICROSCOPY3.28125
196QW6|1|4Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution.ELECTRON MICROSCOPY2.92125
208QP8|1|4Cryo-EM Structure of Pre-B Complex (core part)ELECTRON MICROSCOPY3.576
218QXD|1|4Cryo-EM structure of the cross-exon pre-B complexELECTRON MICROSCOPY9.6124
228R08|1|4Cryo-EM structure of the cross-exon pre-B+AMPPNP complexELECTRON MICROSCOPY6.1124
238QP9|1|4Cryo-EM Structure of Pre-B+AMPPNP Complex (core part)ELECTRON MICROSCOPY4.176
248QPK|1|4Cryo-EM Structure of Pre-B+5'ss Complex (core part)ELECTRON MICROSCOPY4.276
258R0A|1|4Cryo-EM structure of the cross-exon pre-B+5'ss complexELECTRON MICROSCOPY5.8124
263JCR|1|M3D structure determination of the human*U4/U6.U5* tri-snRNP complexELECTRON MICROSCOPY7103

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


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