Equivalence class NR_3.0_16055.1 Current
| # | IFE | Standardized name | Molecule | Organism | Source | Rfam | Title | Method | Res. Å | #NTs | Date |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 7QQP|1|A+ 7QQP|1|C+ 7QQP|1|D (rep) | Trans-activating crRNA | AAVS1 off-target3 non-target strand, AAVS1 off-target3 target strand, AAVS1 sgRNA | synthetic construct | Synthetic | RF02348 | SpCas9 bound to AAVS1 off-target3 DNA substrate | X-ray diffraction | 2.6 | 123 | 2022-10-26 |
| 2 | 7QQR|1|A+ 7QQR|1|C+ 7QQR|1|D | Trans-activating crRNA | AAVS1 off-target5 non-target strand, AAVS1 off-target5 target strand, AAVS1 sgRNA | synthetic construct | Synthetic | RF02348 | SpCas9 bound to AAVS1 off-target5 DNA substrate | X-ray diffraction | 2.75 | 122 | 2022-10-26 |
| 3 | 7QR7|1|A+ 7QR7|1|C+ 7QR7|1|D | Trans-activating crRNA | AAVS1 off-target2 non-target strand, AAVS1 off-target2 target strand, AAVS1 sgRNA | synthetic construct | Synthetic | RF02348 | SpCas9 bound to AAVS1 off-target2 DNA substrate | X-ray diffraction | 3 | 123 | 2022-10-26 |
| 4 | 7QQO|1|A+ 7QQO|1|C+ 7QQO|1|D | Trans-activating crRNA | AAVS1 off-target1 non-target strand, AAVS1 off-target1 target strand, AAVS1 sgRNA | synthetic construct | Synthetic | RF02348 | SpCas9 bound to AAVS1 off-target1 DNA substrate | X-ray diffraction | 3 | 122 | 2022-10-26 |
| 5 | 7QQQ|1|A+ 7QQQ|1|C+ 7QQQ|1|D | Trans-activating crRNA | AAVS1 off-target4 non-target strand, AAVS1 off-target4 target strand, AAVS1 sgRNA | synthetic construct | Synthetic | RF02348 | SpCas9 bound to AAVS1 off-target4 DNA substrate | X-ray diffraction | 2.65 | 121 | 2022-10-26 |
| 6 | 7OX9|1|A+ 7OX9|1|C+ 7OX9|1|D | Trans-activating crRNA | AAVS1 non-target DNA strand, AAVS1 target DNA strand, sgRNA | synthetic construct | Synthetic | RF02348 | Target-bound SpCas9 complex with AAVS1 all-RNA guide | X-ray diffraction | 2.45 | 123 | 2021-09-15 |
Release history
Parents
| This class | Parent classes | Release id | Intersection | Added to this class | Only in parent |
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Children
| This class | Descendant classes | Release id | Intersection | Only in this class | Added to child |
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Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.
| #S | View | PDB | Title | Method | Resolution | #NTs |
|---|---|---|---|---|---|---|
| 1 | 7QQR|1|A+ 7QQR|1|C+ 7QQR|1|D | SpCas9 bound to AAVS1 off-target5 DNA substrate | X-RAY DIFFRACTION | 2.75 | 122 | |
| 2 | 7OX9|1|A+ 7OX9|1|C+ 7OX9|1|D | Target-bound SpCas9 complex with AAVS1 all-RNA guide | X-RAY DIFFRACTION | 2.45 | 123 | |
| 3 | 7QQO|1|A+ 7QQO|1|C+ 7QQO|1|D | SpCas9 bound to AAVS1 off-target1 DNA substrate | X-RAY DIFFRACTION | 3 | 122 | |
| 4 | 7QQP|1|A+ 7QQP|1|C+ 7QQP|1|D | SpCas9 bound to AAVS1 off-target3 DNA substrate | X-RAY DIFFRACTION | 2.6 | 123 | |
| 5 | 7QQQ|1|A+ 7QQQ|1|C+ 7QQQ|1|D | SpCas9 bound to AAVS1 off-target4 DNA substrate | X-RAY DIFFRACTION | 2.65 | 121 | |
| 6 | 7QR7|1|A+ 7QR7|1|C+ 7QR7|1|D | SpCas9 bound to AAVS1 off-target2 DNA substrate | X-RAY DIFFRACTION | 3 | 123 |
Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.
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