#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. Å#NTsDate
18GLP|1|L5+ 8GLP|1|L8 (rep)Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)Electron microscopy1.6737022023-04-19
28A3D|1|A+ 8A3D|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human mature large subunit of the ribosome with eIF6 and homoharringtonine boundElectron microscopy1.6734512023-03-08
38G5Y|1|L5+ 8G5Y|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)Electron microscopy2.2938772023-04-19
47XNY|1|L1+ 7XNY|1|L3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsElectron microscopy2.539292023-04-05
56ZMI|1|L5+ 6ZMI|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complexElectron microscopy2.639292020-08-19
67OW7|1|A+ 7OW7|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002EIF6-bound large subunit of the human ribosomeElectron microscopy2.234512022-10-05
76ZM7|1|L5+ 6ZM7|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complexElectron microscopy2.739292020-07-29
88G60|1|L5+ 8G60|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)Electron microscopy2.5437932023-04-19
97XNX|1|L1+ 7XNX|1|L3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cellsElectron microscopy2.739292023-04-05
108G5Z|1|L5+ 8G5Z|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)Electron microscopy2.6438432023-04-19
117F5S|1|L5+ 7F5S|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human delta-METTL18 60S ribosomeElectron microscopy2.7238712022-06-22
128FL3|1|L3+ 8FL3|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State I2)Electron microscopy2.5336482023-07-12
136Y6X|1|L5+ 6Y6X|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Tetracenomycin X bound to the human ribosomeElectron microscopy2.839292020-07-08
146Z6N|1|L5+ 6Z6N|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)Electron microscopy2.939282020-07-29
158FLE|1|L3+ 8FLE|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State L2)Electron microscopy2.4835262023-07-12
168FLB|1|L3+ 8FLB|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State K2)Electron microscopy2.5535742023-07-12
178FL7|1|L3+ 8FL7|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State J2)Electron microscopy2.5535632023-07-12
188G6J|1|L5+ 8G6J|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)Electron microscopy2.838432023-04-19
196QZP|1|L5+ 6QZP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA (3773-MER), 5.8S rRNA (156-MER)Homo sapiensEukaryaRF02543 + RF00002High-resolution cryo-EM structure of the human 80S ribosomeElectron microscopy2.939292019-04-24
206ZME|1|L5+ 6ZME|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complexElectron microscopy339292020-08-12
216Z6L|1|L5+ 6Z6L|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human CCDC124 bound to 80S ribosomesElectron microscopy339282020-07-29
227QVP|1|L5+ 7QVP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human collided disome (di-ribosome) stalled on XBP1 mRNAElectron microscopy337672022-10-12
238FLD|1|L3+ 8FLD|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State L1)Electron microscopy2.5835262023-07-12
248FL6|1|L3+ 8FL6|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State J1)Electron microscopy2.6235592023-07-12
258FLA|1|L3+ 8FLA|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State K1)Electron microscopy2.6335742023-07-12
268FL2|1|L3+ 8FL2|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State I1)Electron microscopy2.6736492023-07-12
277QVP|1|L6+ 7QVP|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human collided disome (di-ribosome) stalled on XBP1 mRNAElectron microscopy337282022-10-12
286XA1|1|L5+ 6XA1|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Structure of a drug-like compound stalled human translation termination complexElectron microscopy2.836652020-10-07
298FLF|1|L3+ 8FLF|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State L3)Electron microscopy2.6534792023-07-12
308G61|1|L5+ 8G61|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)Electron microscopy2.9438132023-04-19
318FL9|1|L3+ 8FL9|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State J3)Electron microscopy2.7535152023-07-12
328FLC|1|L3+ 8FLC|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State K3)Electron microscopy2.7635272023-07-12
336Y2L|1|L5+ 6Y2L|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in POST stateElectron microscopy337692020-04-15
348FL4|1|L3+ 8FL4|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State I3)Electron microscopy2.8936402023-07-12
358FKY|1|L3+ 8FKY|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State F)Electron microscopy2.6727402023-07-12
368FKW|1|L3+ 8FKW|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State D2)Electron microscopy2.524292023-07-12
378FKV|1|L3+ 8FKV|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State D1)Electron microscopy2.4723652023-07-12
388FKX|1|L3+ 8FKX|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State E)Electron microscopy2.5924022023-07-12
398FKU|1|L3+ 8FKU|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State C2)Electron microscopy2.8223372023-07-12
408FKT|1|L3+ 8FKT|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State C1)Electron microscopy2.8122772023-07-12
418FKS|1|L3+ 8FKS|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State B2)Electron microscopy2.8819762023-07-12
428FKR|1|L3+ 8FKR|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State B1)Electron microscopy2.8919212023-07-12
438FKQ|1|L3+ 8FKQ|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State A2)Electron microscopy2.7617152023-07-12
448FKP|1|L3+ 8FKP|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State A1)Electron microscopy2.8516592023-07-12
458FL0|1|L3Large subunit ribosomal RNA28S rRNAHomo sapiensEukaryaRF02543Human nucleolar pre-60S ribosomal subunit (State H)Electron microscopy2.9115582023-07-12

Release history

Release3.2913.2923.2933.294
Date2023-07-122023-07-192023-07-262023-08-02

Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.

#SViewPDBTitleMethodResolution#NTs
18FL2|1|L3+ 8FL2|1|L1Human nuclear pre-60S ribosomal subunit (State I1)ELECTRON MICROSCOPY2.673649
28FL3|1|L3+ 8FL3|1|L1Human nuclear pre-60S ribosomal subunit (State I2)ELECTRON MICROSCOPY2.533648
38FL4|1|L3+ 8FL4|1|L1Human nuclear pre-60S ribosomal subunit (State I3)ELECTRON MICROSCOPY2.893640
48FLC|1|L3+ 8FLC|1|L1Human nuclear pre-60S ribosomal subunit (State K3)ELECTRON MICROSCOPY2.763527
58FL9|1|L3+ 8FL9|1|L1Human nuclear pre-60S ribosomal subunit (State J3)ELECTRON MICROSCOPY2.753515
68FLB|1|L3+ 8FLB|1|L1Human nuclear pre-60S ribosomal subunit (State K2)ELECTRON MICROSCOPY2.553574
78FLA|1|L3+ 8FLA|1|L1Human nuclear pre-60S ribosomal subunit (State K1)ELECTRON MICROSCOPY2.633574
88FL7|1|L3+ 8FL7|1|L1Human nuclear pre-60S ribosomal subunit (State J2)ELECTRON MICROSCOPY2.553563
98FL6|1|L3+ 8FL6|1|L1Human nuclear pre-60S ribosomal subunit (State J1)ELECTRON MICROSCOPY2.623559
108FLD|1|L3+ 8FLD|1|L1Human nuclear pre-60S ribosomal subunit (State L1)ELECTRON MICROSCOPY2.583526
118FLE|1|L3+ 8FLE|1|L1Human nuclear pre-60S ribosomal subunit (State L2)ELECTRON MICROSCOPY2.483526
128FLF|1|L3+ 8FLF|1|L1Human nuclear pre-60S ribosomal subunit (State L3)ELECTRON MICROSCOPY2.653479
138G61|1|L5+ 8G61|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)ELECTRON MICROSCOPY2.943813
148G5Y|1|L5+ 8G5Y|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)ELECTRON MICROSCOPY2.293877
158GLP|1|L5+ 8GLP|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)ELECTRON MICROSCOPY1.673702
168G5Z|1|L5+ 8G5Z|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)ELECTRON MICROSCOPY2.643843
178G6J|1|L5+ 8G6J|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)ELECTRON MICROSCOPY2.83843
188A3D|1|A+ 8A3D|1|CHuman mature large subunit of the ribosome with eIF6 and homoharringtonine boundELECTRON MICROSCOPY1.673451
197OW7|1|A+ 7OW7|1|CEIF6-bound large subunit of the human ribosomeELECTRON MICROSCOPY2.23451
208G60|1|L5+ 8G60|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)ELECTRON MICROSCOPY2.543793
216XA1|1|L5+ 6XA1|1|L8Structure of a drug-like compound stalled human translation termination complexELECTRON MICROSCOPY2.83665
227F5S|1|L5+ 7F5S|1|L8human delta-METTL18 60S ribosomeELECTRON MICROSCOPY2.723871
236QZP|1|L5+ 6QZP|1|L8High-resolution cryo-EM structure of the human 80S ribosomeELECTRON MICROSCOPY2.93929
246Y2L|1|L5+ 6Y2L|1|L8Structure of human ribosome in POST stateELECTRON MICROSCOPY33769
257QVP|1|L5+ 7QVP|1|L8Human collided disome (di-ribosome) stalled on XBP1 mRNAELECTRON MICROSCOPY33767
267XNY|1|L1+ 7XNY|1|L3High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsELECTRON MICROSCOPY2.53929
277XNX|1|L1+ 7XNX|1|L3High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cellsELECTRON MICROSCOPY2.73929
286Y6X|1|L5+ 6Y6X|1|L8Tetracenomycin X bound to the human ribosomeELECTRON MICROSCOPY2.83929
296Z6N|1|L5+ 6Z6N|1|L8Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)ELECTRON MICROSCOPY2.93928
306Z6L|1|L5+ 6Z6L|1|L8Cryo-EM structure of human CCDC124 bound to 80S ribosomesELECTRON MICROSCOPY33928
316ZM7|1|L5+ 6ZM7|1|L8SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complexELECTRON MICROSCOPY2.73929
326ZMI|1|L5+ 6ZMI|1|L8SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complexELECTRON MICROSCOPY2.63929
336ZME|1|L5+ 6ZME|1|L8SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complexELECTRON MICROSCOPY33929
347QVP|1|L6+ 7QVP|1|L1Human collided disome (di-ribosome) stalled on XBP1 mRNAELECTRON MICROSCOPY33728
358FKY|1|L3+ 8FKY|1|L1Human nucleolar pre-60S ribosomal subunit (State F)ELECTRON MICROSCOPY2.672740
368FKX|1|L3+ 8FKX|1|L1Human nucleolar pre-60S ribosomal subunit (State E)ELECTRON MICROSCOPY2.592402
378FKU|1|L3+ 8FKU|1|L1Human nucleolar pre-60S ribosomal subunit (State C2)ELECTRON MICROSCOPY2.822337
388FKW|1|L3+ 8FKW|1|L1Human nucleolar pre-60S ribosomal subunit (State D2)ELECTRON MICROSCOPY2.52429
398FKV|1|L3+ 8FKV|1|L1Human nucleolar pre-60S ribosomal subunit (State D1)ELECTRON MICROSCOPY2.472365
408FKT|1|L3+ 8FKT|1|L1Human nucleolar pre-60S ribosomal subunit (State C1)ELECTRON MICROSCOPY2.812277
418FKR|1|L3+ 8FKR|1|L1Human nucleolar pre-60S ribosomal subunit (State B1)ELECTRON MICROSCOPY2.891921
428FKP|1|L3+ 8FKP|1|L1Human nucleolar pre-60S ribosomal subunit (State A1)ELECTRON MICROSCOPY2.851659
438FKQ|1|L3+ 8FKQ|1|L1Human nucleolar pre-60S ribosomal subunit (State A2)ELECTRON MICROSCOPY2.761715
448FKS|1|L3+ 8FKS|1|L1Human nucleolar pre-60S ribosomal subunit (State B2)ELECTRON MICROSCOPY2.881976
458FL0|1|L3Human nucleolar pre-60S ribosomal subunit (State H)ELECTRON MICROSCOPY2.911558

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


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