Equivalence class NR_3.0_83835.1 Obsolete
| # | IFE | Standardized name | Molecule | Organism | Source | Rfam | Title | Method | Res. Å | #NTs | Date |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 5B2T|1|A+ 5B2T|1|C+ 5B2T|1|D (rep) | Trans-activating crRNA | Guide RNA, Non-target DNA, DNA (5'-D(*TP*GP*CP*GP*AP*TP*TP*G)-3'), Target DNA | Streptococcus pyogenes | Bacteria | RF02348 | Crystal structure of the Streptococcus pyogenes Cas9 VRER variant in complex with sgRNA and target DNA (TGCG PAM) | X-ray diffraction | 2.2 | 117 | 2016-03-23 |
| 2 | 5B2R|1|A+ 5B2R|1|C+ 5B2R|1|D | Trans-activating crRNA | Guide RNA, Non-target DNA, DNA (5'-D(*TP*GP*AP*GP*AP*TP*TP*G)-3'), Target DNA | Streptococcus pyogenes | Bacteria | RF02348 | Crystal structure of the Streptococcus pyogenes Cas9 VQR variant in complex with sgRNA and target DNA (TGA PAM) | X-ray diffraction | 2 | 117 | 2016-03-23 |
| 3 | 5B2S|1|A+ 5B2S|1|C+ 5B2S|1|D | Trans-activating crRNA | Guide RNA, Non-target DNA, DNA (5'-D(*TP*GP*AP*GP*AP*TP*TP*G)-3'), Target DNA | Streptococcus pyogenes | Bacteria | RF02348 | Crystal structure of the Streptococcus pyogenes Cas9 EQR variant in complex with sgRNA and target DNA (TGAG PAM) | X-ray diffraction | 2.2 | 117 | 2016-03-23 |
| 4 | 6AI6|1|B+ 6AI6|1|C+ 6AI6|1|D | Trans-activating crRNA | DNA (28-MER), DNA (8-MER), RNA (81-MER) | Streptococcus pyogenes | Bacteria | RF02348 | Crystal structure of SpCas9-NG | X-ray diffraction | 2.7 | 117 | 2018-10-31 |
| 5 | 4OO8|1|B+ 4OO8|1|C | DNA (5'-D(*CP*CP*AP*GP*CP*CP*AP*AP*GP*CP*GP*CP*AP*CP*CP*TP*AP*AP*TP*TP*TP*CP*C)-3'), RNA (97-MER) | RF02348 | Crystal structure of Streptococcus pyogenes Cas9 in complex with guide RNA and target DNA | X-ray diffraction | 2.5 | 118 | 2014-02-26 | |||
| 6 | 4OO8|1|E+ 4OO8|1|F | DNA (5'-D(*CP*CP*AP*GP*CP*CP*AP*AP*GP*CP*GP*CP*AP*CP*CP*TP*AP*AP*TP*TP*TP*CP*C)-3'), RNA (97-MER) | RF02348 | Crystal structure of Streptococcus pyogenes Cas9 in complex with guide RNA and target DNA | X-ray diffraction | 2.5 | 120 | 2014-02-26 | |||
| 7 | 8SRS|1|B+ 8SRS|1|D+ 8SRS|1|c+ 8SRS|1|C | Trans-activating crRNA | gRNA, NTS, TS | Streptococcus pyogenes | Bacteria | RF02348 | SpRY-Cas9:gRNA complex targeting TAC PAM DNA | Electron microscopy | 2.79 | 149 | 2024-05-01 |
| 8 | 8T6Y|1|B | Trans-activating crRNA | gRNA | Streptococcus pyogenes | Bacteria | RF02348 | SpRY-Cas9:gRNA complex bound to non-target DNA with 1 bp R-loop | Electron microscopy | 2.88 | 88 | 2024-05-01 |
Parents
| This class | Parent classes | Release id | Intersection | Added to this class | Only in parent |
|---|
Children
| This class | Descendant classes | Release id | Intersection | Only in this class | Added to child |
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Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.
| #S | View | PDB | Title | Method | Resolution | #NTs |
|---|---|---|---|---|---|---|
| 1 | 4OO8|1|E+ 4OO8|1|F | Crystal structure of Streptococcus pyogenes Cas9 in complex with guide RNA and target DNA | X-RAY DIFFRACTION | 2.5 | 120 | |
| 2 | 5B2S|1|A+ 5B2S|1|C+ 5B2S|1|D | Crystal structure of the Streptococcus pyogenes Cas9 EQR variant in complex with sgRNA and target DNA (TGAG PAM) | X-RAY DIFFRACTION | 2.2 | 117 | |
| 3 | 5B2R|1|A+ 5B2R|1|C+ 5B2R|1|D | Crystal structure of the Streptococcus pyogenes Cas9 VQR variant in complex with sgRNA and target DNA (TGA PAM) | X-RAY DIFFRACTION | 2 | 117 | |
| 4 | 5B2T|1|A+ 5B2T|1|C+ 5B2T|1|D | Crystal structure of the Streptococcus pyogenes Cas9 VRER variant in complex with sgRNA and target DNA (TGCG PAM) | X-RAY DIFFRACTION | 2.2 | 117 | |
| 5 | 6AI6|1|B+ 6AI6|1|C+ 6AI6|1|D | Crystal structure of SpCas9-NG | X-RAY DIFFRACTION | 2.7 | 117 | |
| 6 | 4OO8|1|B+ 4OO8|1|C | Crystal structure of Streptococcus pyogenes Cas9 in complex with guide RNA and target DNA | X-RAY DIFFRACTION | 2.5 | 118 | |
| 7 | 8T6Y|1|B | SpRY-Cas9:gRNA complex bound to non-target DNA with 1 bp R-loop | ELECTRON MICROSCOPY | 2.88 | 88 | |
| 8 | 8SRS|1|B+ 8SRS|1|D+ 8SRS|1|c+ 8SRS|1|C | SpRY-Cas9:gRNA complex targeting TAC PAM DNA | ELECTRON MICROSCOPY | 2.79 | 149 |
Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.
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