| 1 | 3BBM|1|B+ 3BBM|1|C+ 3BBM|1|A (rep) | | Loop A and Loop B Ribozyme strand, Loop A Substrate strand, Loop B S-turn strand | | | | Minimally Junctioned Hairpin Ribozyme Incorporates A38C and 2'O-Me Modification at Active Site | X-ray diffraction | 2.65 | 61 | 2008-08-12 |
| 2 | 3B5S|1|B+ 3B5S|1|C+ 3B5S|1|A | | 29-mer Loop A and Loop B Ribozyme strand, Loop A Substrate strand, Loop B S-turn strand | | | | Minimally Hinged Hairpin Ribozyme Incorporates A38DAP Mutation and 2'-O-methyl Modification at the Active Site | X-ray diffraction | 2.25 | 61 | 2008-08-12 |
| 3 | 3B5A|1|B+ 3B5A|1|C+ 3B5A|1|A | | 29-mer Loop A and Loop B Ribozyme strand, Loop A Substrate strand, Loop B S-turn strand | | | | Crystal Structure of a Minimally Hinged Hairpin Ribozyme Incorporating A38G mutation with a 2'OMe modification at the active site | X-ray diffraction | 2.35 | 61 | 2008-08-12 |
| 4 | 3BBI|1|B+ 3BBI|1|C+ 3BBI|1|A | | Loop A and Loop B Ribozyme strand, Loop A Substrate strand, Loop B S-turn strand | | | | Minimally Junctioned Hairpin Ribozyme Incorporating A38(2AP) and A-1 2'-O-Me Modifications near Active Site | X-ray diffraction | 2.35 | 61 | 2008-08-12 |
| 5 | 3BBK|1|B+ 3BBK|1|C+ 3BBK|1|A | | Loop A and Loop B Ribozyme strand, Loop A Substrate strand, Loop B S-turn strand | | | | Miminally Junctioned Hairpin Ribozyme Incorporates A38C and 2'5'-phosphodiester Linkage within Active Site | X-ray diffraction | 2.75 | 61 | 2008-08-12 |
| 6 | 3B91|1|B+ 3B91|1|C+ 3B91|1|A | | 29-mer Loop A and Loop B Ribozyme strand, Loop A Substrate strand, Loop B S-turn strand | | | | Minimally Hinged Hairpin Ribozyme Incorporates Ade38(2AP) and 2',5'-Phosphodiester Linkage Mutations at the Active Site | X-ray diffraction | 2.75 | 61 | 2008-08-12 |
| 7 | 3B5F|1|B+ 3B5F|1|C+ 3B5F|1|A | | 29-mer Loop A and Loop B Ribozyme strand, Loop A Substrate strand, Loop B S-turn strand | | | | Crystal Structure of a Minimally Hinged Hairpin Ribozyme Incorporating the Ade38Dap Mutation and a 2',5' Phosphodiester Linkage at the Active Site | X-ray diffraction | 2.7 | 61 | 2008-08-12 |
| 8 | 3B58|1|B+ 3B58|1|C+ 3B58|1|A | | 29-mer Loop A and Loop B Ribozyme strand, Loop A Substrate strand, Loop B S-turn strand | | | | Minimally Junctioned Hairpin Ribozyme Incorporates A38G Mutation and a 2',5'-Phosphodiester Linkage at the Active Site | X-ray diffraction | 2.65 | 61 | 2008-08-12 |
| 9 | 4G6P|1|B+ 4G6P|1|C+ 4G6P|1|A | | Loop A and Loop B Ribozyme strand, Loop A Substrate strand, Loop B of the Ribozyme Strand | | | | Minimal Hairpin Ribozyme in the Precatalytic State with A38P Variation | X-ray diffraction | 2.64 | 61 | 2012-08-15 |
| 10 | 4G6S|1|B+ 4G6S|1|C+ 4G6S|1|A | | Loop A and Loop B Ribozyme strand, Loop A Substrate strand, Loop B of the Ribozyme Strand | | | | Minimal Hairpin Ribozyme in the Transition State with A38P Variation | X-ray diffraction | 2.84 | 61 | 2012-08-08 |
| 11 | 3CR1|1|B+ 3CR1|1|C+ 3CR1|1|A | | loop A and B ribozyme strand, RNA (5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3'), RNA (5'-R(*UP*CP*GP*UP*GP*GP*UP*CP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3') | | | | crystal structure of a minimal, mutant, all-RNA hairpin ribozyme (A38C, A-1OMA) grown from MgCl2 | X-ray diffraction | 2.25 | 61 | 2008-08-26 |
| 12 | 3I2Q|1|B+ 3I2Q|1|C+ 3I2Q|1|A | | 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', DNA/RNA (30-MER) | | | | Crystal structure of the hairpin ribozyme with 2'OMe substrate strand and N1-deazaadenosine at position A9 | X-ray diffraction | 2.9 | 61 | 2009-11-03 |
| 13 | 3I2S|1|B+ 3I2S|1|C+ 3I2S|1|A | | 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', DNA/RNA (30-MER) | | | | Crystal structure of the hairpin ribozyme with a 2'OMe substrate and N1-deazaadenosine at position A10 | X-ray diffraction | 2.75 | 61 | 2009-11-03 |
| 14 | 3CQS|1|B+ 3CQS|1|C+ 3CQS|1|A | | 13-mer substrate strand with 3'-OH, 2',5'-phosphodiester covalently linking 5th and 6th nucleotides, 19-mer ribozyme strand, 29-mer ribozyme strand with S9L synthetic linker at 13th position | | | | A 3'-OH, 2',5'-phosphodiester substitution in the hairpin ribozyme active site reveals similarities with protein ribonucleases | X-ray diffraction | 2.8 | 61 | 2008-05-20 |
| 15 | 3I2R|1|B+ 3I2R|1|C+ 3I2R|1|A | | 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', DNA/RNA (30-MER) | | | | Crystal structure of the hairpin ribozyme with a 2',5'-linked substrate with N1-deazaadenosine at position A9 | X-ray diffraction | 2.8 | 61 | 2009-11-03 |
| 16 | 3I2U|1|B+ 3I2U|1|C+ 3I2U|1|A | | 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', DNA/RNA (30-MER) | | | | Crystal structure of the haiprin ribozyme with a 2',5'-linked substrate and N1-deazaadenosine at position A10 | X-ray diffraction | 2.8 | 61 | 2009-11-03 |