#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. ÅDate
17Z4D|1|A (rep)sgRNAsynthetic constructCrystal structure of SpCas9 bound to a 10 nucleotide complementary DNA substrateX-ray diffraction3.12022-08-31
27Z4D|1|FsgRNAsynthetic constructCrystal structure of SpCas9 bound to a 10 nucleotide complementary DNA substrateX-ray diffraction3.12022-08-31
37Z4L|1|AsgRNAsynthetic constructSpCas9 bound to 18-nucleotide complementary DNA substrate in the checkpoint stateElectron microscopy2.542022-08-31
47S4X|1|BgRNAsynthetic constructCas9:gRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformationElectron microscopy2.762022-03-02
57Z4J|1|AsgRNAsynthetic constructSpCas9 bound to 18-nucleotide complementary DNA substrate in the catalytic stateElectron microscopy2.992022-08-31
68U3Y|1|BRNA (98-MER)synthetic constructSpG Cas9 with NGG PAM DNA targetElectron microscopy3.12024-05-01
76O0X|1|Bsingle guide RNAsynthetic constructConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumElectron microscopy3.282019-07-10
87Z4I|1|AsgRNAsynthetic constructSpCas9 bound to 16-nucleotide complementary DNA substrateElectron microscopy3.122022-08-31
97S4V|1|BgRNAsynthetic constructCas9 bound to 12-14MM DNA, 60 min time-point, kinked conformationElectron microscopy3.282022-03-02
106O0Y|1|Bsingle guide RNAsynthetic constructConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumElectron microscopy3.372019-07-10
116O0Z|1|Bsingle guide RNAsynthetic constructConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumElectron microscopy3.32019-07-10
128TZZ|1|BRNA (98-MER)synthetic constructSpG Cas9 with NGC PAM DNA targetElectron microscopy3.562024-05-01
137S4U|1|BgRNAsynthetic constructCryo-EM structure of Cas9 in complex with 12-14MM DNA substrate, 5 minute time-pointElectron microscopy3.562022-03-02
147Z4H|1|AsgRNAsynthetic constructSpCas9 bound to 14-nucleotide complementary DNA substrateElectron microscopy3.492022-08-31
157Z4G|1|AsgRNAsynthetic constructSpCas9 bound to 12-nucleotide complementary DNA substrateElectron microscopy3.642022-08-31
167Z4C|1|AsgRNAsynthetic constructSpCas9 bound to 6 nucleotide complementary DNA substrateElectron microscopy3.872022-08-31
177Z4K|1|AsgRNAsynthetic constructSpCas9 bound to 10-nucleotide complementary DNA substrateElectron microscopy3.812022-08-31

Release history

Release3.3333.3343.3353.3363.3373.3383.3393.3403.3413.3423.3433.3443.3453.3463.3473.3483.3493.3503.3513.3523.3533.3543.3553.3563.357
Date2024-05-012024-05-082024-05-152024-05-222024-05-292024-06-052024-06-122024-06-192024-06-262024-07-032024-07-102024-07-172024-07-252024-07-312024-08-072024-08-142024-08-212024-08-282024-09-042024-09-112024-09-182024-09-252024-10-022024-10-092024-10-16

Parents

This classParent classesRelease idIntersectionAdded to this classOnly in parent

Children

This class Descendant classesRelease idIntersectionOnly in this classAdded to child

Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.

#SViewPDBTitleMethodResolutionLength
17S4V|1|BCas9 bound to 12-14MM DNA, 60 min time-point, kinked conformationELECTRON MICROSCOPY3.2898
26O0Z|1|BConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.396
36O0X|1|BConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.2898
46O0Y|1|BConformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesiumELECTRON MICROSCOPY3.3798
58TZZ|1|BSpG Cas9 with NGC PAM DNA targetELECTRON MICROSCOPY3.5698
68U3Y|1|BSpG Cas9 with NGG PAM DNA targetELECTRON MICROSCOPY3.198
77Z4J|1|ASpCas9 bound to 18-nucleotide complementary DNA substrate in the catalytic stateELECTRON MICROSCOPY2.9998
87S4X|1|BCas9:gRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformationELECTRON MICROSCOPY2.7698
97Z4C|1|ASpCas9 bound to 6 nucleotide complementary DNA substrateELECTRON MICROSCOPY3.8790
107Z4K|1|ASpCas9 bound to 10-nucleotide complementary DNA substrateELECTRON MICROSCOPY3.8188
117Z4H|1|ASpCas9 bound to 14-nucleotide complementary DNA substrateELECTRON MICROSCOPY3.4992
127Z4G|1|ASpCas9 bound to 12-nucleotide complementary DNA substrateELECTRON MICROSCOPY3.6491
137Z4I|1|ASpCas9 bound to 16-nucleotide complementary DNA substrateELECTRON MICROSCOPY3.1296
147Z4L|1|ASpCas9 bound to 18-nucleotide complementary DNA substrate in the checkpoint stateELECTRON MICROSCOPY2.5496
157Z4D|1|ACrystal structure of SpCas9 bound to a 10 nucleotide complementary DNA substrateX-RAY DIFFRACTION3.175
167Z4D|1|FCrystal structure of SpCas9 bound to a 10 nucleotide complementary DNA substrateX-RAY DIFFRACTION3.177
177S4U|1|BCryo-EM structure of Cas9 in complex with 12-14MM DNA substrate, 5 minute time-pointELECTRON MICROSCOPY3.5697

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


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