#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. Å#NTsDate
16WBR|1|B+ 6WBR|1|C+ 6WBR|1|D (rep)DNA (30-MER), DNA (5'-D(*AP*TP*AP*CP*CP*TP*GP*GP*CP*G)-3'), RNA (94-MER)Acidothermus cellulolyticus 11BCrystal structure of AceCas9 bound with guide RNA and DNA with 5'-NNNCC-3' PAMX-ray diffraction2.911312020-11-18
26WC0|1|B+ 6WC0|1|C+ 6WC0|1|DDNA (30-MER), DNA (5'-D(*AP*TP*AP*CP*TP*TP*GP*GP*CP*G)-3'), sgRNA (95-MER)Acidothermus cellulolyticus 11BCrystal structure of AceCas9 bound with guide RNA and DNA with 5'-NNNTC-3' PAMX-ray diffraction3.611312020-11-18
38D2L|1|B+ 8D2L|1|T+ 8D2L|1|D+ 8D2L|1|XDNA non-target strand (5'-D(P*AP*GP*A)-3'), DNA non-target strand (5'-D(P*TP*AP*TP*AP*CP*AP*CP*CP*AP*AP*GP*CP*T)-3'), DNA target strand (5'-D(*AP*GP*CP*TP*TP*GP*GP*TP*GP*TP*AP*TP*A)-3'), DNA target strand (5'-D(P*CP*CP*AP*GP*GP*AP*TP*CP*TP*TP*GP*CP*CP*AP*TP*CP*CP*TP*AP*CP*CP*TP*CP*T)-3'), Single guide RNA (106-MER)Acidothermus cellulolyticus 11BStructure of Acidothermus cellulolyticus Cas9 ternary complex (Cleavage Intermediate 1)Electron microscopy2.211472023-12-20
48D2K|1|B+ 8D2K|1|T+ 8D2K|1|D+ 8D2K|1|XDNA non-target strand (5'-D(P*AP*GP*A)-3'), DNA non-target strand (5'-D(P*TP*AP*TP*AP*CP*AP*CP*CP*AP*AP*GP*CP*T)-3'), DNA target strand (5'-D(*AP*GP*CP*TP*TP*GP*GP*TP*GP*TP*AP*TP*A)-3'), DNA target strand (5'-D(P*CP*CP*AP*GP*GP*AP*TP*CP*TP*TP*GP*CP*CP*AP*TP*CP*CP*TP*AP*CP*CP*TP*CP*T)-3'), Single Guide RNA (102-MER)Acidothermus cellulolyticusStructure of Acidothermus cellulolyticus Cas9 ternary complex (Cleavage Intermediate 2)Electron microscopy2.431522023-12-20
58D2O|1|B+ 8D2O|1|X+ 8D2O|1|D+ 8D2O|1|TDNA non-target strand (5'-D(P*AP*TP*AP*CP*AP*CP*CP*AP*AP*GP*CP*T)-3'), DNA target strand (5'-D(*AP*GP*CP*TP*TP*GP*GP*TP*GP*TP*AP*TP*A)-3'), DNA target strand (5'-D(P*CP*CP*AP*GP*GP*AP*TP*CP*TP*TP*G)-3'), Single guide RNA (106-MER)Acidothermus cellulolyticus 11BStructure of Acidothermus cellulolyticus Cas9 ternary complex (Post-cleavage 2)Electron microscopy2.661232023-12-20
68D2Q|1|B+ 8D2Q|1|X+ 8D2Q|1|D+ 8D2Q|1|TDNA non-target strand (5'-D(P*AP*TP*AP*CP*AP*CP*CP*AP*AP*GP*CP*T)-3'), DNA target strand (5'-D(*AP*GP*CP*TP*TP*GP*GP*TP*GP*TP*AP*TP*A)-3'), DNA target strand (5'-D(P*CP*CP*AP*GP*GP*AP*TP*CP*TP*TP*G)-3'), Single Guide RNA (86-MER)Acidothermus cellulolyticus 11BStructure of Acidothermus cellulolyticus Cas9 ternary complex (Post-cleavage 1)Electron microscopy2.581222023-12-20
78D2P|1|B+ 8D2P|1|TDNA target strand (5'-D(P*CP*CP*AP*GP*GP*AP*TP*CP*TP*TP*GP*CP*CP*AP*TP*CP*CP*TP*AP*CP*CP*TP*CP*T)-3'), Single guide RNA (102-MER)Acidothermus cellulolyticus 11BStructure of Acidothermus cellulolyticus Cas9 ternary complex (Target bound)Electron microscopy2.781262023-12-20
88D2N|1|B+ 8D2N|1|X+ 8D2N|1|DDNA non-target strand (5'-D(P*TP*AP*CP*AP*CP*CP*AP*AP*GP*CP*T)-3'), DNA target strand (25-MER), Single guide RNA (106-MER)Acidothermus cellulolyticus 11BStructure of Acidothermus cellulolyticus Cas9 ternary complex (Pre-cleavage)Electron microscopy2.881282023-12-20
99AR5|1|B+ 9AR5|1|X+ 9AR5|1|DDNA (25-MER), DNA/RNA (5'-D(P*TP*AP*CP*A)-R(P*(5MC))-D(P*CP*AP*AP*GP*CP*T)-3'), RNA (92-MER)Acidothermus cellulolyticusStructure of Acidothermus cellulolyticus Cas9 bound with methylated DNAElectron microscopy2.881282025-02-26

Release history

Release3.3783.3793.3803.3813.382
Date2025-03-132025-03-192025-03-262025-04-022025-04-09

Parents

This classParent classesRelease idIntersectionAdded to this classOnly in parent

Children

This class Descendant classesRelease idIntersectionOnly in this classAdded to child

Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.

#SViewPDBTitleMethodResolution#NTs
18D2P|1|B+ 8D2P|1|TStructure of Acidothermus cellulolyticus Cas9 ternary complex (Target bound)ELECTRON MICROSCOPY2.78126
28D2L|1|B+ 8D2L|1|T+ 8D2L|1|D+ 8D2L|1|XStructure of Acidothermus cellulolyticus Cas9 ternary complex (Cleavage Intermediate 1)ELECTRON MICROSCOPY2.21147
38D2K|1|B+ 8D2K|1|T+ 8D2K|1|D+ 8D2K|1|XStructure of Acidothermus cellulolyticus Cas9 ternary complex (Cleavage Intermediate 2)ELECTRON MICROSCOPY2.43152
48D2N|1|B+ 8D2N|1|X+ 8D2N|1|DStructure of Acidothermus cellulolyticus Cas9 ternary complex (Pre-cleavage)ELECTRON MICROSCOPY2.88128
58D2Q|1|B+ 8D2Q|1|X+ 8D2Q|1|D+ 8D2Q|1|TStructure of Acidothermus cellulolyticus Cas9 ternary complex (Post-cleavage 1)ELECTRON MICROSCOPY2.58122
68D2O|1|B+ 8D2O|1|X+ 8D2O|1|D+ 8D2O|1|TStructure of Acidothermus cellulolyticus Cas9 ternary complex (Post-cleavage 2)ELECTRON MICROSCOPY2.66123
76WBR|1|B+ 6WBR|1|C+ 6WBR|1|DCrystal structure of AceCas9 bound with guide RNA and DNA with 5'-NNNCC-3' PAMX-RAY DIFFRACTION2.91131
86WC0|1|B+ 6WC0|1|C+ 6WC0|1|DCrystal structure of AceCas9 bound with guide RNA and DNA with 5'-NNNTC-3' PAMX-RAY DIFFRACTION3.61131
99AR5|1|B+ 9AR5|1|X+ 9AR5|1|DStructure of Acidothermus cellulolyticus Cas9 bound with methylated DNAELECTRON MICROSCOPY2.88128

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


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