1 | 6QCW|1|V+ 6QCW|1|R+ 6QCW|1|M (rep) | | RNA (5'-D(*(GDM))-R(P*GP*AP*AP*UP*GP*CP*CP*AP*UP*AP*AP*UP*AP*G)-3'), RNA (5'-R(*UP*AP*UP*AP*CP*CP*UP*CP*UP*GP*CP*UP*UP*CP*UP*GP*CP*UP*AP*UP*U)-3'), RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*GP*AP*G)-3') | synthetic construct | | | Crystal structure of influenza B polymerase initiation state with capped 14-mer RNA primer | X-ray diffraction | 2.88 | 49 | 2019-06-05 |
2 | 6QCX|1|V+ 6QCX|1|R+ 6QCX|1|M | | RNA (5'-D(*(GDM))-R(P*GP*AP*AP*UP*GP*CP*UP*AP*UP*AP*AP*UP*AP*GP*C)-3'), RNA (5'-R(*UP*AP*UP*AP*CP*CP*UP*CP*UP*GP*CP*UP*UP*CP*UP*GP*CP*UP*AP*UP*U)-3'), RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*GP*AP*G)-3') | synthetic construct | | | Crystal structure of influenza B polymerase initiation state with capped 15-mer RNA primer | X-ray diffraction | 3.08 | 50 | 2019-06-05 |
3 | 4WRT|1|V+ 4WRT|1|R | | Influenza virus polymerase vRNA promoter 3' end, Influenza virus polymerase vRNA promoter 5' end | Influenza B virus | | | Crystal structure of Influenza B polymerase with bound vRNA promoter (form FluB2) | X-ray diffraction | 2.7 | 29 | 2014-11-19 |
4 | 6QCV|1|V+ 6QCV|1|R+ 6QCV|1|M | | RNA (5'-D(*(GDM))-R(P*GP*AP*AP*UP*GP*CP*UP*AP*UP*AP*AP*UP*AP*G)-3'), RNA (5'-R(*UP*AP*UP*AP*CP*CP*UP*CP*UP*GP*CP*UP*UP*CP*UP*GP*CP*UP*AP*UP*U)-3'), RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*GP*AP*G)-3') | synthetic construct | | | Crystal structure of influenza B polymerase initiation state with capped 14-mer RNA primer and CTP | X-ray diffraction | 3.24 | 49 | 2019-06-05 |
5 | 7Z43|1|VVV+ 7Z43|1|RRR | | RNA (5'-R(*UP*AP*UP*AP*CP*CP*UP*CP*UP*GP*CP*UP*CP*CP*UP*GP*CP*U)-3'), RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*GP*AP*G)-3') | Influenza B virus | | | Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 1B and 2B | X-ray diffraction | 3.123 | 32 | 2022-05-11 |
6 | 4WSA|1|V+ 4WSA|1|R | | Influenza B vRNA promoter 3' end, Influenza B vRNA promoter 5' end | Influenza B virus | | | Crystal structure of Influenza B polymerase bound to the vRNA promoter (FluB1 form) | X-ray diffraction | 3.4 | 28 | 2014-11-19 |
7 | 5M3J|1|V+ 5M3J|1|R | | RNA (5'-R(*UP*AP*UP*AP*CP*CP*UP*CP*UP*GP*CP*UP*UP*C)-3'), RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*GP*AP*G)-3') | Influenza B virus | | | Influenza B polymerase bound to four heptad repeats of serine 5 phosphorylated Pol II CTD | X-ray diffraction | 3.5 | 28 | 2016-12-21 |
8 | 5MSG|1|V+ 5MSG|1|R | | RNA (5'-R(*UP*AP*UP*AP*CP*CP*UP*CP*UP*GP*CP*UP*UP*CP*UP*GP*CP*U)-3'), RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*GP*AP*G)-3') | Influenza B virus | | | Influenza B polymerase bound to vRNA promoter and capped RNA primer | X-ray diffraction | 3.8 | 32 | 2017-02-08 |
9 | 7R0E|1|V+ 7R0E|1|M+ 7R0E|1|R | | 3' vRNA, 5' vRNA, mRNA | Influenza A virus | | | Early transcription elongation state of influenza A/H7N9 polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the +1 position | Electron microscopy | 2.51 | 51 | 2022-12-28 |
10 | 8BEK|1|V+ 8BEK|1|R+ 8BEK|1|M | | 3' vRNA, 5' vRNA, mRNA | Influenza A virus | | | Early transcription elongation state of influenza A/H7N9 backtracked polymerase with singly incoporated T1106 at the U +1 position | Electron microscopy | 2.86 | 49 | 2022-12-28 |
11 | 6T0N|1|V+ 6T0N|1|R | | 3' vRNA, 5' vRNA | Influenza B virus | | | Bat Influenza A polymerase pre-initiation complex | Electron microscopy | 2.54 | 29 | 2020-04-15 |
12 | 6QCS|1|V+ 6QCS|1|R | | 3 end, 5 end | Influenza B virus | | | Influenza B polymerase pre-initiation complex | Electron microscopy | 3.1 | 29 | 2019-06-05 |
13 | 6SZV|1|V | | 5' vRNA | Influenza B virus | | | Bat Influenza A polymerase elongation complex with incoming UTP analogue (core + endonuclease only) | Electron microscopy | 2.5 | 14 | 2020-04-15 |
14 | 7QTL|1|V | | 5' vRNA | Influenza A virus | | | Influenza A/H7N9 polymerase elongation complex | Electron microscopy | 2.48 | 13 | 2022-12-28 |
15 | 7R1F|1|V | | 5' vRNA | Influenza B virus | | | Early transcription elongation state of influenza B polymerase backtracked due to double incoproation of nucleotide analogue T1106 | Electron microscopy | 2.58 | 12 | 2022-12-28 |
16 | 6T0V|1|V | | 5' vRNA | Influenza A virus | | | Bat Influenza A polymerase elongation complex with incoming UTP analogue (complete polymerase) | Electron microscopy | 3.02 | 14 | 2020-04-15 |
17 | 6QCT|1|V | | 5 end | Influenza B virus | | | Influenza B polymerase elongation complex | Electron microscopy | 3.2 | 13 | 2019-06-05 |
18 | 7ZPL|1|U | | 5' vRNA | Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)) | | | Symmetric dimer of influenza A/H7N9 polymerase bound to 5' vRNA hook | Electron microscopy | 3.12 | 12 | 2022-12-28 |
19 | 7ZPL|1|V | | 5' vRNA | Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)) | | | Symmetric dimer of influenza A/H7N9 polymerase bound to 5' vRNA hook | Electron microscopy | 3.12 | 12 | 2022-12-28 |