#IFEStandardized nameMoleculeOrganismSourceRfamTitleMethodRes. Å#NTsDate
18GLP|1|L5+ 8GLP|1|L8 (rep)Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)Electron microscopy1.6737022023-04-19
29TV2|1|L5+ 9TV2|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF0000280S ribosomes from primary B-cells infected with delta v-snoRNA1 EBVElectron microscopy2.132122026-07-01
39TT7|1|L5+ 9TT7|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF0000280S ribosome of WT EBV infected human B-cellsElectron microscopy2.232112026-07-22
49O3W|1|L5+ 9O3W|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human 80S ribosome bound to IDB-001 stalled on MYC nascent chainElectron microscopy1.937022026-03-04
58QYX|1|A2+ 8QYX|1|C2Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human 60S ribosomal subunitElectron microscopy1.7838622024-12-11
68YOO|1|L5+ 8YOO|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human 80S ribosome with 100 um TigecyclineElectron microscopy238262024-07-10
78QFD|1|5+ 8QFD|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002UFL1 E3 ligase bound 60S ribosomeElectron microscopy2.232742024-02-21
89SPI|1|L5+ 9SPI|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING URIDINEElectron microscopy2.435622026-01-21
99C3H|1|L5+ 9C3H|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Structure of the CNOT3-bound human 80S ribosome with tRNA-ARG in the P-site.Electron microscopy236792024-12-04
108A3D|1|A+ 8A3D|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human mature large subunit of the ribosome with eIF6 and homoharringtonine boundElectron microscopy1.6734512023-03-08
119SPF|1|L5+ 9SPF|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING N1-METHYLPSEUDOURIDINEElectron microscopy2.436222026-01-21
129O3V|1|L5+ 9O3V|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human 80S ribosome stalled on MYC nascent chainElectron microscopy2.237022026-03-04
139S3D|1|L5+ 9S3D|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002NAC bound human RNC with 58 amino acid ARF1-linkerElectron microscopy2.3238042026-02-18
149I2D|1|L5+ 9I2D|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002NMT1-NAC bound human RNC with 10 amino acid ARF1-linkerElectron microscopy2.1938042026-02-04
159S3B|1|L5+ 9S3B|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002NMT1-NAC bound human RNC with 58 amino acid ARF1-linker - State 1Electron microscopy2.3838042026-02-18
169S3C|1|L5+ 9S3C|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002NMT1-NAC bound human RNC with 58 amino acid ARF1-linker - State 2Electron microscopy2.4238042026-02-18
179QLO|1|L5+ 9QLO|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002NMT1-NAC bound human RNC with full length ARF1 - State 1Electron microscopy2.4738042026-02-18
189PBE|1|L5+ 9PBE|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNA [Homo sapiens]Homo sapiensEukaryaRF02543 + RF00002In situ human 80S ribosome (composite map)Electron microscopy2.1938112025-12-24
198G5Y|1|L5+ 8G5Y|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)Electron microscopy2.2938772023-04-19
209RUC|1|L5+ 9RUC|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002WT-HEK 80S ribosome bound to H2B mRNA (WT-H2B)Electron microscopy2.533422026-05-13
219PKD|1|L5+ 9PKD|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ CHX and HHT treated 80S consensus ribosomeElectron microscopy2.4238112026-07-15
229QLQ|1|L5+ 9QLQ|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002NMT1-NAC bound human RNC with full length ARF1 - alternative StateElectron microscopy2.5738042026-02-18
238YOP|1|L5+ 8YOP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human 80S ribosome with 4 um TigecyclineElectron microscopy2.239272024-07-10
249O3Y|1|L5+ 9O3Y|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human 80S ribosome bound to IDB-002 stalled on FPAK-containing nascent chainElectron microscopy2.237022026-03-04
259P7D|1|L5+ 9P7D|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human Hibernating class4 80S ribosomeElectron microscopy2.5738112025-12-24
268QOI|1|L5+ 8QOI|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA (3773-MER), 5.8S rRNA (156-MER)Homo sapiensEukaryaRF02543 + RF00002Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNAElectron microscopy1.939292024-06-12
279P8B|1|L5+ 9P8B|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human eEF1A-A/T-P-E state 80S ribosomeElectron microscopy2.4838112025-12-24
288G5Z|1|L5+ 8G5Z|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)Electron microscopy2.6438432023-04-19
298JDK|1|D+ 8JDK|1|FLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)Electron microscopy2.2636682023-12-06
309P7E|1|L5+ 9P7E|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human Hibernating class5 80S ribosomeElectron microscopy2.5938112025-12-24
318G60|1|L5+ 8G60|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)Electron microscopy2.5437932023-04-19
329RPV|1|M5+ 9RPV|1|M8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA of the stalled 80S, 5.8S rRNA of the stalled 80SHomo sapiensEukaryaRF02543 + RF00002Structure of the ZAK-bound human disomeElectron microscopy2.3537022025-12-10
339GUL|1|L5+ 9GUL|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Structure of FLuc-XBP1u+ stalled human 60S ribosome nascent chain complexElectron microscopy2.238232025-09-24
346ZMI|1|L5+ 6ZMI|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complexElectron microscopy2.639292020-08-19
359FQZ|1|L5+ 9FQZ|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA5.8S rRNA, LSU rRNAHomo sapiensEukaryaRF02543 + RF00002CRYO-EM STRUCTURE OF HCT15 POLYSOMES BOUND TO EEF2, EBP1, AND SERBP1Electron microscopy2.8536302026-01-14
368XSX|1|L5+ 8XSX|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2Electron microscopy2.439272024-07-10
379QLP|1|L5+ 9QLP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, RNA (156-MER)Homo sapiensEukaryaRF02543 + RF00002NMT1-NAC bound human RNC with full length ARF1 - State 2Electron microscopy2.7538042026-02-18
388JDL|1|D+ 8JDL|1|FLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state)Electron microscopy2.4236682023-12-06
399P73|1|L5+ 9P73|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human eEF2-A/P-P/E state 80S ribosomeElectron microscopy2.6638112025-12-24
408JDJ|1|D+ 8JDJ|1|FLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU)Electron microscopy2.536682023-12-06
417F5S|1|L5+ 7F5S|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human delta-METTL18 60S ribosomeElectron microscopy2.7238712022-06-22
428OJ5|1|5+ 8OJ5|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF0000260S ribosomal subunit bound to the E3-UFM1 complex - state 3 (in-vitro reconstitution)Electron microscopy2.936222024-02-21
438K2C|1|L5+ 8K2C|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human 80S ribosome with TigecyclineElectron microscopy2.439272024-07-10
449P7O|1|L5+ 9P7O|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human AT-P-Z state ribosomeElectron microscopy2.6538112025-12-24
459RPV|1|L5+ 9RPV|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA of the collided 80S, 5.8S rRNA of the collided 80SHomo sapiensEukaryaRF02543 + RF00002Structure of the ZAK-bound human disomeElectron microscopy2.3537392025-12-10
469RUA|1|L5+ 9RUA|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002RPS26dC HEK mutant 80S ribosome bound to TISU mRNA (RPS26dC-TISU)Electron microscopy2.936062026-06-03
479P7Y|1|L5+ 9P7Y|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNA [Homo sapiens]Homo sapiensEukaryaRF02543 + RF00002In situ human A-P-E state 80S ribosomeElectron microscopy2.7538112025-12-24
487XNY|1|L1+ 7XNY|1|L3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsElectron microscopy2.539292023-04-05
499P7C|1|L5+ 9P7C|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human Hibernating class3 80S ribosomeElectron microscopy2.7838112025-12-24
508FLE|1|L3+ 8FLE|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State L2)Electron microscopy2.4835262023-07-12
519PA7|1|L5+ 9PA7|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human 80S consensus ribosome with EBP1Electron microscopy2.6738112025-12-24
526ZM7|1|L5+ 6ZM7|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complexElectron microscopy2.739292020-07-29
539P9J|1|L5+ 9P9J|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human 60S ribosomeElectron microscopy2.8738112025-12-24
549MNC|1|L5+ 9MNC|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human 80S ribosome bound to small molecule SW393071Electron microscopy2.3336562026-06-24
559P7A|1|L5+ 9P7A|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human hibernating class2 80S ribosomeElectron microscopy2.8138112025-12-24
569VXN|1|L5+ 9VXN|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human cytosolic ribosome in a rotated state, with multiple neomycin molecules bound, featuring A/P-site and P/E-site tRNAsElectron microscopy2.5138072026-07-22
579P7X|1|L5+ 9P7X|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human A-P-Z state 80S ribosomeElectron microscopy2.8338112025-12-24
589P9I|1|L5+ 9P9I|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human unrotated hibernating without CCDC124 state 80S ribosomeElectron microscopy2.7738112025-12-24
598JDM|1|D+ 8JDM|1|FLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (rotated state)Electron microscopy2.6736682023-12-06
607OW7|1|A+ 7OW7|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002EIF6-bound large subunit of the human ribosomeElectron microscopy2.234512022-10-05
617XNX|1|L1+ 7XNX|1|L3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cellsElectron microscopy2.739292023-04-05
626QZP|1|L5+ 6QZP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA (3773-MER), 5.8S rRNA (156-MER)Homo sapiensEukaryaRF02543 + RF00002High-resolution cryo-EM structure of the human 80S ribosomeElectron microscopy2.939292019-04-24
638IFD|1|1A+ 8IFD|1|1CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Dibekacin-added human 80S ribosomeElectron microscopy2.5938732024-02-14
648FLB|1|L3+ 8FLB|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State K2)Electron microscopy2.5535742023-07-12
658FLD|1|L3+ 8FLD|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State L1)Electron microscopy2.5835262023-07-12
668FL7|1|L3+ 8FL7|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State J2)Electron microscopy2.5535632023-07-12
679P72|1|L5+ 9P72|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNA [Homo sapiens]Homo sapiensEukaryaRF02543 + RF00002In situ human P-E state 80S ribosomeElectron microscopy2.838112025-12-24
689P7K|1|L5+ 9P7K|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human post eEF1A-A/T-P-E state 80S ribosomeElectron microscopy2.838112025-12-24
699P76|1|L5+ 9P76|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human eEF1A-A/T-P state 80S ribosomeElectron microscopy2.8338112025-12-24
709P9H|1|L5+ 9P9H|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human unrotated hibernating with CCDC124 state 80S ribosomeElectron microscopy2.8438112025-12-24
718OHD|1|5+ 8OHD|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF0000260S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native)Electron microscopy3.136222024-02-21
729P78|1|L5+ 9P78|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human Hibernating rotate 3 with E-site tRNA state 80S ribosomeElectron microscopy2.938112025-12-24
736Y2L|1|L5+ 6Y2L|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in POST stateElectron microscopy337692020-04-15
748G61|1|L5+ 8G61|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)Electron microscopy2.9438132023-04-19
759P7N|1|L5+ 9P7N|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human Post-eEF1A-A/T-P-Z state 80S ribosomeElectron microscopy2.8338112025-12-24
768IFE|1|1A+ 8IFE|1|1CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Arbekacin-added human 80S ribosomeElectron microscopy2.5738732024-02-14
779RU9|1|L5+ 9RU9|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA23S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002RPS26dC HEK mutant 80S ribosome bound to Kozak mRNA (RPS26dC-Kozak)Electron microscopy2.9736792026-06-03
786Y6X|1|L5+ 6Y6X|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Tetracenomycin X bound to the human ribosomeElectron microscopy2.839292020-07-08
799GMO|1|A+ 9GMO|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002eIF6-bound pre-60S large ribosomal subunit incorporating mutant uL16Electron microscopy2.5935422024-10-02
809P7W|1|L5+ 9P7W|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human A-P state 80S ribosomeElectron microscopy2.9338112025-12-24
816Z6M|1|L5+ 6Z6M|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1Electron microscopy3.139282020-07-29
826ZME|1|L5+ 6ZME|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complexElectron microscopy339292020-08-12
839P6Z|1|L5+ 9P6Z|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human P-Z state 80S ribosomeElectron microscopy2.9738112025-12-24
849I2E|1|L5+ 9I2E|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002NMT1-NAC bound human ribosome (combined translational states)Electron microscopy2.9539282026-02-04
857QVP|1|L5+ 7QVP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human collided disome (di-ribosome) stalled on XBP1 mRNAElectron microscopy337672022-10-12
869RU8|1|L5+ 9RU8|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002WT-HEK 80S ribosome bound to TISU mRNA (WT-TISU)Electron microscopy335992026-06-03
878FL2|1|L3+ 8FL2|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State I1)Electron microscopy2.6736492023-07-12
886ZMO|1|L5+ 6ZMO|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complexElectron microscopy3.139292020-08-19
899P7L|1|L5+ 9P7L|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human Post-eEF1A-AT-P state 80S ribosomeElectron microscopy2.9238112025-12-24
908FLA|1|L3+ 8FLA|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State K1)Electron microscopy2.6335742023-07-12
919RU7|1|L5+ 9RU7|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002WT-HEK 80S ribosome bound to Kozak mRNA (WT-Kozak)Electron microscopy335272026-05-13
9222TU|1|L5+ 22TU|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human 80S ribosome in complex with DHX29Electron microscopy337752026-04-01
938FL6|1|L3+ 8FL6|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State J1)Electron microscopy2.6235592023-07-12
949KZU|1|L5+ 9KZU|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S_ribosomal_RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the HCV IRES-dependently initiated CMV-stalled 80S ribosome (non-rotated state) in complexed with eIF3Electron microscopy338192025-12-03
958FL3|1|L3+ 8FL3|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State I2)Electron microscopy2.5336482023-07-12
968Y0X|1|L5+ 8Y0X|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Dormant ribosome with SERBP1Electron microscopy3.338142024-02-07
978Y0W|1|L5+ 8Y0W|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002dormant ribosome with eIF5A, eEF2 and SERBP1Electron microscopy3.438222024-02-07
989B0P|1|L5+ 9B0P|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA [Homo sapiens], 5.8S rRNA [Homo sapiens]Homo sapiensEukaryaRF02543 + RF00002In situ human Hibernating class1 80S ribosomeElectron microscopy2.8238962025-03-19
996LQM|1|2+ 6LQM|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state CElectron microscopy3.0936882020-08-26
1009GY4|1|5+ 9GY4|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF0000260S ribosomal subunit in complex with E3-UFM1 ligase and RQC machinery components NEMF and LTN1 (Composite map)Electron microscopy336762025-05-14
1018IDT|1|2+ 8IDT|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State GElectron microscopy2.836802023-08-09
1029WW4|1|AA+ 9WW4|1|ACLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA (3773-MER), 5.8S rRNA (156-MER)Homo sapiensEukaryaRF02543 + RF00002human 80S ribosome non-rotated stateElectron microscopy2.4839292026-09-16
1039PKB|1|L5+ 9PKB|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ HHT and CHX treated human hibernating state 80S ribosomeElectron microscopy3.0538112026-07-15
1049P9K|1|L5+ 9P9K|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human 60S ribosome with EIF6Electron microscopy2.9638112025-12-24
1058G6J|1|L5+ 8G6J|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)Electron microscopy2.838432023-04-19
1066Y0G|1|L5+ 6Y0G|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in classical-PRE stateElectron microscopy3.238002020-04-15
1079P8H|1|L5+ 9P8H|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human A/P-P/E state 80S ribosomeElectron microscopy2.9838112025-12-24
1088INF|1|2+ 8INF|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State F'Electron microscopy338082023-08-09
1098FLF|1|L3+ 8FLF|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State L3)Electron microscopy2.6534792023-07-12
1109N9J|1|L5+ 9N9J|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of a GRP94 folding intermediate engaged with a CCDC134- and FKBP11-bound secretory transloconElectron microscopy3.238742025-11-19
1117QVP|1|L6+ 7QVP|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human collided disome (di-ribosome) stalled on XBP1 mRNAElectron microscopy337282022-10-12
1129I14|1|L5+ 9I14|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA5.8S rRNA, LSU 28S rRNAHomo sapiensEukaryaRF02543 + RF00002CRYO-EM STRUCTURE OF HCT15 POLYSOMES IN HYBRID-PRE STATEElectron microscopy3.3436122026-01-28
1136OM0|1|t+ 6OM0|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAsElectron microscopy3.137642019-06-19
1148XSY|1|L5+ 8XSY|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head Swivelled)Electron microscopy339272024-07-10
1158OJ8|1|5+ 8OJ8|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF0000260S ribosomal subunit bound to the E3-UFM1 complex - state 1 (native)Electron microscopy3.336632024-02-21
1169G8M|1|L5+ 9G8M|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002human 80S ribosome bound by a SKI2-exosome complexElectron microscopy3.338102024-10-23
1178OJ0|1|5+ 8OJ0|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF0000260S ribosomal subunit bound to the E3-UFM1 complex - state 2 (native)Electron microscopy3.336222024-02-21
1186LSR|1|2+ 6LSR|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state BElectron microscopy3.1336372020-08-26
1196OLE|1|t+ 6OLE|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAsElectron microscopy3.137642019-06-19
12028LN|1|B5+ 28LN|1|B8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002XBP1u-stalled RPL4 RNC in complex with NACElectron microscopy2.737942026-06-10
1216XA1|1|L5+ 6XA1|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Structure of a drug-like compound stalled human translation termination complexElectron microscopy2.836652020-10-07
1226LU8|1|2+ 6LU8|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a human pre-60S ribosomal subunit - state AElectron microscopy3.1336332020-08-26
1238FKV|1|L3+ 8FKV|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State D1)Electron microscopy2.4723652023-07-12
1248FL9|1|L3+ 8FL9|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State J3)Electron microscopy2.7535152023-07-12
1258RL2|1|L5+ 8RL2|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human pre-60S - State 5Electron microscopy2.8435382025-01-15
1269P8C|1|L5+ 9P8C|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human Hibernating class1 (rotate3) without E tRNA state 80S ribosomeElectron microscopy3.1138112025-12-24
1279P79|1|L5+ 9P79|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human Hibernating rotate3 with Z site tRNA state 80S ribosomeElectron microscopy3.138112025-12-24
1288FKW|1|L3+ 8FKW|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State D2)Electron microscopy2.524292023-07-12
1298XSZ|1|L5+ 8XSZ|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNAElectron microscopy3.238242024-07-10
1309KZX|1|L5+ 9KZX|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S_ribosomal_RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the HCV IRES-dependently initiated CMV-stalled 80S ribosome (rotated state) in complexed with eIF3Electron microscopy3.337452025-12-03
1319QIW|1|L5+ 9QIW|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human pre-60S - State 3Electron microscopy3.0432932025-04-30
1328IDY|1|2+ 8IDY|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State FElectron microscopy337972023-08-09
1337BHP|1|L5+ 7BHP|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human Ebp1 - 80S ribosomeElectron microscopy3.338002021-02-03
1348FLC|1|L3+ 8FLC|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State K3)Electron microscopy2.7635272023-07-12
1359M0P|1|L5+ 9M0P|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA|HOMO SAPIENS, 5.8S ribosomal RNA|HOMO SAPIENSHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human 80S ribosome in complex with montanineElectron microscopy2.7834432026-01-14
1366Y57|1|L5+ 6Y57|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome in hybrid-PRE stateElectron microscopy3.537302020-04-15
1378INE|1|2+ 8INE|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State G'Electron microscopy3.236922023-08-09
1389WW5|1|AA+ 9WW5|1|ACLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA (3773-MER), 5.8S rRNA (156-MER)Homo sapiensEukaryaRF02543 + RF00002human 80S ribosome rotated stateElectron microscopy2.6939292026-09-16
1396LSS|1|2+ 6LSS|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of a pre-60S ribosomal subunit - state preAElectron microscopy3.2336302020-08-26
1408FKY|1|L3+ 8FKY|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State F)Electron microscopy2.6727402023-07-12
1418FKX|1|L3+ 8FKX|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State E)Electron microscopy2.5924022023-07-12
1429B0Q|1|l5+ 9B0Q|1|l8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA [Homo sapiens], RNA (156-MER)5.8S rRNA [Homo sapiens]Homo sapiensEukaryaRF02543 + RF00002In situ human top-back di-ribosome structure (Composite map)Electron microscopy3.238642025-03-19
1439PKG|1|L5+ 9PKG|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In situ human P state 80S ribosomeElectron microscopy3.2638112025-12-24
1448IPY|1|2+ 8IPY|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State D'Electron microscopy3.236412023-08-09
1458INK|1|2+ 8INK|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State DElectron microscopy3.236512023-08-09
1469B0S|1|l5+ 9B0S|1|l8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA [Homo sapiens], 5.8S rRNA [Homo sapiens]Homo sapiensEukaryaRF02543 + RF00002In situ human top-top di-ribosome structure (Composite map)Electron microscopy3.838962025-03-19
1479Y4G|1|A6+ 9Y4G|1|A5+ 9Y4G|1|A8Large subunit ribosomal RNA + Large subunit ribosomal RNA + 5.8S ribosomal RNA5.8S rRNA (157-MER), LSU-alpha rRNA, LSU-beta rRNA (2108-MER)CtenomyidaeEukaryotaRF02543 + RF02543 + RF00002Structure of tuco-tuco ribosome (rotated, tRNAs, and mRNA)Electron microscopy3.339922026-02-18
1489SYR|1|L1+ 9SYR|1|L3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatDElectron microscopy3.5535512025-12-17
1498FL4|1|L3+ 8FL4|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nuclear pre-60S ribosomal subunit (State I3)Electron microscopy2.8936402023-07-12
1509B0Q|1|L5+ 9B0Q|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA [Homo sapiens], RNA (156-MER)5.8S rRNA [Homo sapiens]Homo sapiensEukaryaRF02543 + RF00002In situ human top-back di-ribosome structure (Composite map)Electron microscopy3.238642025-03-19
1514UG0|1|L5+ 4UG0|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002STRUCTURE OF THE HUMAN 80S RIBOSOMEElectron microscopy3.639322015-06-10
1528IPD|1|2+ 8IPD|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State CElectron microscopy3.236412023-08-09
1539P7G|1|L5+ 9P7G|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA [Homo sapiens], 5.8S rRNA [Homo sapiens]Homo sapiensEukaryaRF02543 + RF00002In situ HHT and CHX treated A-P-Z state 80S ribosomeElectron microscopy3.5438112025-12-24
1549P7F|1|L5+ 9P7F|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA [Homo sapiens], 5.8S rRNA [Homo sapiens]Homo sapiensEukaryaRF02543 + RF00002In situ HHT and CHX treated A-P state 80S ribosomeElectron microscopy3.5638112025-12-24
1558FKQ|1|L3+ 8FKQ|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State A2)Electron microscopy2.7617152023-07-12
1568FKU|1|L3+ 8FKU|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State C2)Electron microscopy2.8223372023-07-12
1578FKS|1|L3+ 8FKS|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State B2)Electron microscopy2.8819762023-07-12
1588FKT|1|L3+ 8FKT|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State C1)Electron microscopy2.8122772023-07-12
1596OLI|1|t+ 6OLI|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)Electron microscopy3.537642019-06-19
1608FKR|1|L3+ 8FKR|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State B1)Electron microscopy2.8919212023-07-12
1619B0S|1|L5+ 9B0S|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA [Homo sapiens], 5.8S rRNA [Homo sapiens]Homo sapiensEukaryaRF02543 + RF00002In situ human top-top di-ribosome structure (Composite map)Electron microscopy3.838962025-03-19
1628IE3|1|2+ 8IE3|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State EElectron microscopy3.336752023-08-09
1639P7I|1|L5+ 9P7I|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA [Homo sapiens], 5.8S rRNA [Homo sapiens]Homo sapiensEukaryaRF02543 + RF00002In situ HHT and CHX treated human eEF1A-A/T-P-Z state 80S ribosomeElectron microscopy3.6938112025-12-24
1649Y49|1|A6+ 9Y49|1|A5+ 9Y49|1|A8Large subunit ribosomal RNA + Large subunit ribosomal RNA + 5.8S ribosomal RNA5.8S rRNA (157-MER), LSU-alpha rRNA (1722-MER), LSU-beta rRNA (2069-MER)CtenomyidaeEukaryotaRF02543 + RF02543 + RF00002Structure of tuco-tuco ribosome with P/E tRNA and eEF2 (rotated)Electron microscopy3.439412026-02-18
1658ONY|1|5Large subunit ribosomal RNA28S rRNAHomo sapiensEukaryaRF02543Human Methionine Aminopeptidase 2 at the 80S ribosomeElectron microscopy2.921562024-02-21
1669P7H|1|L5+ 9P7H|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA [Homo sapiens], 5.8S rRNA [Homo sapiens]Homo sapiensEukaryaRF02543 + RF00002In situ HHT and CHX treated human eEF1A-A/T-P state 80S ribosomeElectron microscopy3.6838112025-12-24
1678FKP|1|L3+ 8FKP|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State A1)Electron microscopy2.8516592023-07-12
1688IR1|1|2+ 8IR1|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRMAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State AElectron microscopy3.335242023-08-09
1698IR3|1|2+ 8IR3|1|8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002human nuclear pre-60S ribosomal particle - State B'Electron microscopy3.536962023-08-09
1706IP5|1|1A+ 6IP5|1|1CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)Electron microscopy3.938732019-05-29
1719P8I|1|L5+ 9P8I|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA [Homo sapiens], 5.8S rRNA [Homo sapiens]Homo sapiensEukaryaRF02543 + RF00002In situ HHT and CHX treated human P-Z state 80S ribosomeElectron microscopy3.8938112025-12-24
1729P7J|1|L5+ 9P7J|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA [Homo sapiens], 5.8S rRNA [Homo sapiens]Homo sapiensEukaryaRF02543 + RF00002In situ HHT and CHX treated human P state 80S ribosomeElectron microscopy3.9138112025-12-24
1735T2C|1|A+ 5T2C|1|CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002CryoEM structure of the human ribosome at 3.6 Angstrom resolutionElectron microscopy3.639322017-01-25
1746W6L|1|t+ 6W6L|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the human ribosome-TMCO1 transloconElectron microscopy3.8436672020-09-02
1756OLG|1|A2+ 6OLG|1|A3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)Electron microscopy3.437692019-06-19
1768FKZ|1|L3+ 8FKZ|1|L1Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Human nucleolar pre-60S ribosomal subunit (State G)Electron microscopy3.0429872023-07-12
1776IP8|1|1A+ 6IP8|1|1CLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)Electron microscopy3.938232019-05-29
1786OLF|1|t+ 6OLF|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAsElectron microscopy3.937642019-06-19
1795LKS|1|L5+ 5LKS|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Structure-function insights reveal the human ribosome as a cancer target for antibioticsElectron microscopy3.639322017-04-26
1806OLZ|1|A2+ 6OLZ|1|A3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNAElectron microscopy3.938002019-06-19
1818FL0|1|L3Large subunit ribosomal RNA28S rRNAHomo sapiensEukaryaRF02543Human nucleolar pre-60S ribosomal subunit (State H)Electron microscopy2.9115582023-07-12
1827ZFW|1|L5Large subunit ribosomal RNARNA (615-MER)Homo sapiensEukaryaRF02543Structure of human 80S ribosome obtained from ssDNA coated gridElectron microscopy3.86152022-11-23
1836OM7|1|t+ 6OM7|1|DLarge subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAsElectron microscopy3.737642019-06-19
1849GJ6|1|1Large subunit ribosomal RNA28S rRNAHomo sapiensEukaryaRF02543Human 80S ribosome in complex with NatA in proximal and distal positionElectron microscopy3.915522026-02-18
1855A8L|1|ALarge subunit ribosomal RNA28S RIBOSOMAL RNAHomo sapiensEukaryaRF02543Human eRF1 and the hCMV nascent peptide in the translation termination complexElectron microscopy3.82532015-12-02
1866SXO|1|L5Large subunit ribosomal RNA28S ribosomal RNA including ES27L-B (2839-3265)Homo sapiensEukaryaRF02543Cryo-EM structure of the human Ebp1-ribosome complexElectron microscopy3.32682020-02-19
1876Z6N|1|L5+ 6Z6N|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)Electron microscopy2.939282020-07-29
1886Z6L|1|L5+ 6Z6L|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002Cryo-EM structure of human CCDC124 bound to 80S ribosomesElectron microscopy339282020-07-29
1895AJ0|1|A2+ 5AJ0|1|A3Large subunit ribosomal RNA + 5.8S ribosomal RNA28S ribosomal RNA, 5.8S ribosomal RNAHomo sapiensEukaryaRF02543 + RF00002Cryo electron microscopy of actively translating human polysomes (POST state).Electron microscopy3.537692015-05-20
1909RG7|1|L5+ 9RG7|1|L8Large subunit ribosomal RNA + 5.8S ribosomal RNA28S rRNA, 5.8S rRNAHomo sapiensEukaryaRF02543 + RF00002In vitro reconstituted NAA40-NAC bound 80SElectron microscopy2.7238252026-06-17

Release history

Release4.57
Date2026-09-16

Parents

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Instances are ordered to put similar structures near each other. Select one instance to see its 3D structure. Selecting two or more instances will show their superposition, but only chains with identical numbers of observed nucleotides will superpose well. Large structures are slow to display; this tool is not designed for that.

#SViewPDBTitleMethodResolution#NTs
19Y49|1|A6+ 9Y49|1|A5+ 9Y49|1|A8Structure of tuco-tuco ribosome with P/E tRNA and eEF2 (rotated)ELECTRON MICROSCOPY3.43941
29Y4G|1|A6+ 9Y4G|1|A5+ 9Y4G|1|A8Structure of tuco-tuco ribosome (rotated, tRNAs, and mRNA)ELECTRON MICROSCOPY3.33992
39B0Q|1|L5+ 9B0Q|1|L8In situ human top-back di-ribosome structure (Composite map)ELECTRON MICROSCOPY3.23864
46Y6X|1|L5+ 6Y6X|1|L8Tetracenomycin X bound to the human ribosomeELECTRON MICROSCOPY2.83929
56Z6N|1|L5+ 6Z6N|1|L8Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)ELECTRON MICROSCOPY2.93928
66Z6L|1|L5+ 6Z6L|1|L8Cryo-EM structure of human CCDC124 bound to 80S ribosomesELECTRON MICROSCOPY33928
76QZP|1|L5+ 6QZP|1|L8High-resolution cryo-EM structure of the human 80S ribosomeELECTRON MICROSCOPY2.93929
87ZFW|1|L5Structure of human 80S ribosome obtained from ssDNA coated gridELECTRON MICROSCOPY3.8615
96Y0G|1|L5+ 6Y0G|1|L8Structure of human ribosome in classical-PRE stateELECTRON MICROSCOPY3.23800
107BHP|1|L5+ 7BHP|1|L8Cryo-EM structure of the human Ebp1 - 80S ribosomeELECTRON MICROSCOPY3.33800
118JDK|1|D+ 8JDK|1|FStructure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)ELECTRON MICROSCOPY2.263668
128JDJ|1|D+ 8JDJ|1|FStructure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU)ELECTRON MICROSCOPY2.53668
138JDL|1|D+ 8JDL|1|FStructure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state)ELECTRON MICROSCOPY2.423668
148JDM|1|D+ 8JDM|1|FStructure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (rotated state)ELECTRON MICROSCOPY2.673668
158QFD|1|5+ 8QFD|1|8UFL1 E3 ligase bound 60S ribosomeELECTRON MICROSCOPY2.23274
169RU7|1|L5+ 9RU7|1|L8WT-HEK 80S ribosome bound to Kozak mRNA (WT-Kozak)ELECTRON MICROSCOPY33527
179RU8|1|L5+ 9RU8|1|L8WT-HEK 80S ribosome bound to TISU mRNA (WT-TISU)ELECTRON MICROSCOPY33599
189RUA|1|L5+ 9RUA|1|L8RPS26dC HEK mutant 80S ribosome bound to TISU mRNA (RPS26dC-TISU)ELECTRON MICROSCOPY2.93606
196XA1|1|L5+ 6XA1|1|L8Structure of a drug-like compound stalled human translation termination complexELECTRON MICROSCOPY2.83665
208G60|1|L5+ 8G60|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)ELECTRON MICROSCOPY2.543793
219RUC|1|L5+ 9RUC|1|L8WT-HEK 80S ribosome bound to H2B mRNA (WT-H2B)ELECTRON MICROSCOPY2.53342
228G5Z|1|L5+ 8G5Z|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)ELECTRON MICROSCOPY2.643843
238G6J|1|L5+ 8G6J|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)ELECTRON MICROSCOPY2.83843
248G61|1|L5+ 8G61|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)ELECTRON MICROSCOPY2.943813
258G5Y|1|L5+ 8G5Y|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)ELECTRON MICROSCOPY2.293877
268GLP|1|L5+ 8GLP|1|L8mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)ELECTRON MICROSCOPY1.673702
279RU9|1|L5+ 9RU9|1|L8RPS26dC HEK mutant 80S ribosome bound to Kozak mRNA (RPS26dC-Kozak)ELECTRON MICROSCOPY2.973679
289O3W|1|L5+ 9O3W|1|L8Human 80S ribosome bound to IDB-001 stalled on MYC nascent chainELECTRON MICROSCOPY1.93702
299O3Y|1|L5+ 9O3Y|1|L8Human 80S ribosome bound to IDB-002 stalled on FPAK-containing nascent chainELECTRON MICROSCOPY2.23702
309O3V|1|L5+ 9O3V|1|L8Human 80S ribosome stalled on MYC nascent chainELECTRON MICROSCOPY2.23702
319SPF|1|L5+ 9SPF|1|L8CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING N1-METHYLPSEUDOURIDINEELECTRON MICROSCOPY2.43622
329SPI|1|L5+ 9SPI|1|L8CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING URIDINEELECTRON MICROSCOPY2.43562
339RPV|1|M5+ 9RPV|1|M8Structure of the ZAK-bound human disomeELECTRON MICROSCOPY2.353702
348OJ5|1|5+ 8OJ5|1|860S ribosomal subunit bound to the E3-UFM1 complex - state 3 (in-vitro reconstitution)ELECTRON MICROSCOPY2.93622
358OJ8|1|5+ 8OJ8|1|860S ribosomal subunit bound to the E3-UFM1 complex - state 1 (native)ELECTRON MICROSCOPY3.33663
368OJ0|1|5+ 8OJ0|1|860S ribosomal subunit bound to the E3-UFM1 complex - state 2 (native)ELECTRON MICROSCOPY3.33622
378OHD|1|5+ 8OHD|1|860S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native)ELECTRON MICROSCOPY3.13622
389GY4|1|5+ 9GY4|1|860S ribosomal subunit in complex with E3-UFM1 ligase and RQC machinery components NEMF and LTN1 (Composite map)ELECTRON MICROSCOPY33676
399GMO|1|A+ 9GMO|1|CeIF6-bound pre-60S large ribosomal subunit incorporating mutant uL16ELECTRON MICROSCOPY2.593542
408A3D|1|A+ 8A3D|1|CHuman mature large subunit of the ribosome with eIF6 and homoharringtonine boundELECTRON MICROSCOPY1.673451
417OW7|1|A+ 7OW7|1|CEIF6-bound large subunit of the human ribosomeELECTRON MICROSCOPY2.23451
429VXN|1|L5+ 9VXN|1|L8Human cytosolic ribosome in a rotated state, with multiple neomycin molecules bound, featuring A/P-site and P/E-site tRNAsELECTRON MICROSCOPY2.513807
438QOI|1|L5+ 8QOI|1|L8Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNAELECTRON MICROSCOPY1.93929
449WW4|1|AA+ 9WW4|1|AChuman 80S ribosome non-rotated stateELECTRON MICROSCOPY2.483929
459WW5|1|AA+ 9WW5|1|AChuman 80S ribosome rotated stateELECTRON MICROSCOPY2.693929
467F5S|1|L5+ 7F5S|1|L8human delta-METTL18 60S ribosomeELECTRON MICROSCOPY2.723871
479RG7|1|L5+ 9RG7|1|L8In vitro reconstituted NAA40-NAC bound 80SELECTRON MICROSCOPY2.723825
488YOO|1|L5+ 8YOO|1|L8Cryo-EM structure of the human 80S ribosome with 100 um TigecyclineELECTRON MICROSCOPY23826
498YOP|1|L5+ 8YOP|1|L8Cryo-EM structure of the human 80S ribosome with 4 um TigecyclineELECTRON MICROSCOPY2.23927
508K2C|1|L5+ 8K2C|1|L8Cryo-EM structure of the human 80S ribosome with TigecyclineELECTRON MICROSCOPY2.43927
518XSY|1|L5+ 8XSY|1|L8Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head Swivelled)ELECTRON MICROSCOPY33927
528XSZ|1|L5+ 8XSZ|1|L8Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNAELECTRON MICROSCOPY3.23824
538XSX|1|L5+ 8XSX|1|L8Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2ELECTRON MICROSCOPY2.43927
549FQZ|1|L5+ 9FQZ|1|L8CRYO-EM STRUCTURE OF HCT15 POLYSOMES BOUND TO EEF2, EBP1, AND SERBP1ELECTRON MICROSCOPY2.853630
559I2E|1|L5+ 9I2E|1|L8NMT1-NAC bound human ribosome (combined translational states)ELECTRON MICROSCOPY2.953928
569B0P|1|L5+ 9B0P|1|L8In situ human Hibernating class1 80S ribosomeELECTRON MICROSCOPY2.823896
579B0Q|1|l5+ 9B0Q|1|l8In situ human top-back di-ribosome structure (Composite map)ELECTRON MICROSCOPY3.23864
589B0S|1|l5+ 9B0S|1|l8In situ human top-top di-ribosome structure (Composite map)ELECTRON MICROSCOPY3.83896
599P8H|1|L5+ 9P8H|1|L8In situ human A/P-P/E state 80S ribosomeELECTRON MICROSCOPY2.983811
609P73|1|L5+ 9P73|1|L8In situ human eEF2-A/P-P/E state 80S ribosomeELECTRON MICROSCOPY2.663811
619P78|1|L5+ 9P78|1|L8In situ human Hibernating rotate 3 with E-site tRNA state 80S ribosomeELECTRON MICROSCOPY2.93811
629P7A|1|L5+ 9P7A|1|L8In situ human hibernating class2 80S ribosomeELECTRON MICROSCOPY2.813811
639P7C|1|L5+ 9P7C|1|L8In situ human Hibernating class3 80S ribosomeELECTRON MICROSCOPY2.783811
649PKB|1|L5+ 9PKB|1|L8In situ HHT and CHX treated human hibernating state 80S ribosomeELECTRON MICROSCOPY3.053811
659P7D|1|L5+ 9P7D|1|L8In situ human Hibernating class4 80S ribosomeELECTRON MICROSCOPY2.573811
669P7E|1|L5+ 9P7E|1|L8In situ human Hibernating class5 80S ribosomeELECTRON MICROSCOPY2.593811
679B0S|1|L5+ 9B0S|1|L8In situ human top-top di-ribosome structure (Composite map)ELECTRON MICROSCOPY3.83896
689P9J|1|L5+ 9P9J|1|L8In situ human 60S ribosomeELECTRON MICROSCOPY2.873811
699P9K|1|L5+ 9P9K|1|L8In situ human 60S ribosome with EIF6ELECTRON MICROSCOPY2.963811
709P9I|1|L5+ 9P9I|1|L8In situ human unrotated hibernating without CCDC124 state 80S ribosomeELECTRON MICROSCOPY2.773811
719P9H|1|L5+ 9P9H|1|L8In situ human unrotated hibernating with CCDC124 state 80S ribosomeELECTRON MICROSCOPY2.843811
729P8B|1|L5+ 9P8B|1|L8In situ human eEF1A-A/T-P-E state 80S ribosomeELECTRON MICROSCOPY2.483811
739P7K|1|L5+ 9P7K|1|L8In situ human post eEF1A-A/T-P-E state 80S ribosomeELECTRON MICROSCOPY2.83811
749P76|1|L5+ 9P76|1|L8In situ human eEF1A-A/T-P state 80S ribosomeELECTRON MICROSCOPY2.833811
759P72|1|L5+ 9P72|1|L8In situ human P-E state 80S ribosomeELECTRON MICROSCOPY2.83811
769P7L|1|L5+ 9P7L|1|L8In situ human Post-eEF1A-AT-P state 80S ribosomeELECTRON MICROSCOPY2.923811
779PKG|1|L5+ 9PKG|1|L8In situ human P state 80S ribosomeELECTRON MICROSCOPY3.263811
789P7H|1|L5+ 9P7H|1|L8In situ HHT and CHX treated human eEF1A-A/T-P state 80S ribosomeELECTRON MICROSCOPY3.683811
799P7J|1|L5+ 9P7J|1|L8In situ HHT and CHX treated human P state 80S ribosomeELECTRON MICROSCOPY3.913811
809PA7|1|L5+ 9PA7|1|L8In situ human 80S consensus ribosome with EBP1ELECTRON MICROSCOPY2.673811
819PBE|1|L5+ 9PBE|1|L8In situ human 80S ribosome (composite map)ELECTRON MICROSCOPY2.193811
829P7Y|1|L5+ 9P7Y|1|L8In situ human A-P-E state 80S ribosomeELECTRON MICROSCOPY2.753811
839P7W|1|L5+ 9P7W|1|L8In situ human A-P state 80S ribosomeELECTRON MICROSCOPY2.933811
849P7G|1|L5+ 9P7G|1|L8In situ HHT and CHX treated A-P-Z state 80S ribosomeELECTRON MICROSCOPY3.543811
859P8C|1|L5+ 9P8C|1|L8In situ human Hibernating class1 (rotate3) without E tRNA state 80S ribosomeELECTRON MICROSCOPY3.113811
869P6Z|1|L5+ 9P6Z|1|L8In situ human P-Z state 80S ribosomeELECTRON MICROSCOPY2.973811
879PKD|1|L5+ 9PKD|1|L8In situ CHX and HHT treated 80S consensus ribosomeELECTRON MICROSCOPY2.423811
889P7O|1|L5+ 9P7O|1|L8In situ human AT-P-Z state ribosomeELECTRON MICROSCOPY2.653811
899P7N|1|L5+ 9P7N|1|L8In situ human Post-eEF1A-A/T-P-Z state 80S ribosomeELECTRON MICROSCOPY2.833811
909P7I|1|L5+ 9P7I|1|L8In situ HHT and CHX treated human eEF1A-A/T-P-Z state 80S ribosomeELECTRON MICROSCOPY3.693811
919P8I|1|L5+ 9P8I|1|L8In situ HHT and CHX treated human P-Z state 80S ribosomeELECTRON MICROSCOPY3.893811
929P7X|1|L5+ 9P7X|1|L8In situ human A-P-Z state 80S ribosomeELECTRON MICROSCOPY2.833811
939P7F|1|L5+ 9P7F|1|L8In situ HHT and CHX treated A-P state 80S ribosomeELECTRON MICROSCOPY3.563811
949P79|1|L5+ 9P79|1|L8In situ human Hibernating rotate3 with Z site tRNA state 80S ribosomeELECTRON MICROSCOPY3.13811
959I2D|1|L5+ 9I2D|1|L8NMT1-NAC bound human RNC with 10 amino acid ARF1-linkerELECTRON MICROSCOPY2.193804
969S3B|1|L5+ 9S3B|1|L8NMT1-NAC bound human RNC with 58 amino acid ARF1-linker - State 1ELECTRON MICROSCOPY2.383804
979S3C|1|L5+ 9S3C|1|L8NMT1-NAC bound human RNC with 58 amino acid ARF1-linker - State 2ELECTRON MICROSCOPY2.423804
989S3D|1|L5+ 9S3D|1|L8NAC bound human RNC with 58 amino acid ARF1-linkerELECTRON MICROSCOPY2.323804
999QLP|1|L5+ 9QLP|1|L8NMT1-NAC bound human RNC with full length ARF1 - State 2ELECTRON MICROSCOPY2.753804
1009QLO|1|L5+ 9QLO|1|L8NMT1-NAC bound human RNC with full length ARF1 - State 1ELECTRON MICROSCOPY2.473804
1019QLQ|1|L5+ 9QLQ|1|L8NMT1-NAC bound human RNC with full length ARF1 - alternative StateELECTRON MICROSCOPY2.573804
1026Y2L|1|L5+ 6Y2L|1|L8Structure of human ribosome in POST stateELECTRON MICROSCOPY33769
1037QVP|1|L5+ 7QVP|1|L8Human collided disome (di-ribosome) stalled on XBP1 mRNAELECTRON MICROSCOPY33767
10422TU|1|L5+ 22TU|1|L8Human 80S ribosome in complex with DHX29ELECTRON MICROSCOPY33775
1059I14|1|L5+ 9I14|1|L8CRYO-EM STRUCTURE OF HCT15 POLYSOMES IN HYBRID-PRE STATEELECTRON MICROSCOPY3.343612
1069RPV|1|L5+ 9RPV|1|L8Structure of the ZAK-bound human disomeELECTRON MICROSCOPY2.353739
1076Y57|1|L5+ 6Y57|1|L8Structure of human ribosome in hybrid-PRE stateELECTRON MICROSCOPY3.53730
1087QVP|1|L6+ 7QVP|1|L1Human collided disome (di-ribosome) stalled on XBP1 mRNAELECTRON MICROSCOPY33728
1099KZX|1|L5+ 9KZX|1|L8Cryo-EM structure of the HCV IRES-dependently initiated CMV-stalled 80S ribosome (rotated state) in complexed with eIF3ELECTRON MICROSCOPY3.33745
1108Y0W|1|L5+ 8Y0W|1|L8dormant ribosome with eIF5A, eEF2 and SERBP1ELECTRON MICROSCOPY3.43822
1118Y0X|1|L5+ 8Y0X|1|L8Dormant ribosome with SERBP1ELECTRON MICROSCOPY3.33814
1126Z6M|1|L5+ 6Z6M|1|L8Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1ELECTRON MICROSCOPY3.13928
1136ZME|1|L5+ 6ZME|1|L8SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complexELECTRON MICROSCOPY33929
1145A8L|1|AHuman eRF1 and the hCMV nascent peptide in the translation termination complexELECTRON MICROSCOPY3.8253
1156ZMO|1|L5+ 6ZMO|1|L8SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complexELECTRON MICROSCOPY3.13929
1166ZMI|1|L5+ 6ZMI|1|L8SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complexELECTRON MICROSCOPY2.63929
1176ZM7|1|L5+ 6ZM7|1|L8SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complexELECTRON MICROSCOPY2.73929
1187XNX|1|L1+ 7XNX|1|L3High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cellsELECTRON MICROSCOPY2.73929
1197XNY|1|L1+ 7XNY|1|L3High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cellsELECTRON MICROSCOPY2.53929
1209MNC|1|L5+ 9MNC|1|L1Human 80S ribosome bound to small molecule SW393071ELECTRON MICROSCOPY2.333656
1219C3H|1|L5+ 9C3H|1|L1Structure of the CNOT3-bound human 80S ribosome with tRNA-ARG in the P-site.ELECTRON MICROSCOPY23679
1228IFD|1|1A+ 8IFD|1|1CDibekacin-added human 80S ribosomeELECTRON MICROSCOPY2.593873
1238IFE|1|1A+ 8IFE|1|1CArbekacin-added human 80S ribosomeELECTRON MICROSCOPY2.573873
1246IP5|1|1A+ 6IP5|1|1CCryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)ELECTRON MICROSCOPY3.93873
1256IP8|1|1A+ 6IP8|1|1CCryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)ELECTRON MICROSCOPY3.93823
1269KZU|1|L5+ 9KZU|1|L8Cryo-EM structure of the HCV IRES-dependently initiated CMV-stalled 80S ribosome (non-rotated state) in complexed with eIF3ELECTRON MICROSCOPY33819
1276LQM|1|2+ 6LQM|1|8Cryo-EM structure of a pre-60S ribosomal subunit - state CELECTRON MICROSCOPY3.093688
1286LSR|1|2+ 6LSR|1|8Cryo-EM structure of a pre-60S ribosomal subunit - state BELECTRON MICROSCOPY3.133637
1299SYR|1|L1+ 9SYR|1|L3Human quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatDELECTRON MICROSCOPY3.553551
1309N9J|1|L5+ 9N9J|1|L8Structure of a GRP94 folding intermediate engaged with a CCDC134- and FKBP11-bound secretory transloconELECTRON MICROSCOPY3.23874
1319GUL|1|L5+ 9GUL|1|L8Structure of FLuc-XBP1u+ stalled human 60S ribosome nascent chain complexELECTRON MICROSCOPY2.23823
1328QYX|1|A2+ 8QYX|1|C2Human 60S ribosomal subunitELECTRON MICROSCOPY1.783862
13328LN|1|B5+ 28LN|1|B8XBP1u-stalled RPL4 RNC in complex with NACELECTRON MICROSCOPY2.73794
1349M0P|1|L5+ 9M0P|1|L8Cryo-EM structure of human 80S ribosome in complex with montanineELECTRON MICROSCOPY2.783443
1354UG0|1|L5+ 4UG0|1|L8STRUCTURE OF THE HUMAN 80S RIBOSOMEELECTRON MICROSCOPY3.63932
1365T2C|1|A+ 5T2C|1|CCryoEM structure of the human ribosome at 3.6 Angstrom resolutionELECTRON MICROSCOPY3.63932
1379G8M|1|L5+ 9G8M|1|L8human 80S ribosome bound by a SKI2-exosome complexELECTRON MICROSCOPY3.33810
1385LKS|1|L5+ 5LKS|1|L8Structure-function insights reveal the human ribosome as a cancer target for antibioticsELECTRON MICROSCOPY3.63932
1395AJ0|1|A2+ 5AJ0|1|A3Cryo electron microscopy of actively translating human polysomes (POST state).ELECTRON MICROSCOPY3.53769
1406OLG|1|A2+ 6OLG|1|A3Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)ELECTRON MICROSCOPY3.43769
1416OLZ|1|A2+ 6OLZ|1|A3Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNAELECTRON MICROSCOPY3.93800
1426OM0|1|t+ 6OM0|1|DHuman ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAsELECTRON MICROSCOPY3.13764
1436OLE|1|t+ 6OLE|1|DHuman ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAsELECTRON MICROSCOPY3.13764
1446OLI|1|t+ 6OLI|1|DStructure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)ELECTRON MICROSCOPY3.53764
1456OLF|1|t+ 6OLF|1|DHuman ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAsELECTRON MICROSCOPY3.93764
1466OM7|1|t+ 6OM7|1|DHuman ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAsELECTRON MICROSCOPY3.73764
1476W6L|1|t+ 6W6L|1|DCryo-EM structure of the human ribosome-TMCO1 transloconELECTRON MICROSCOPY3.843667
1488FLF|1|L3+ 8FLF|1|L1Human nuclear pre-60S ribosomal subunit (State L3)ELECTRON MICROSCOPY2.653479
1498FLE|1|L3+ 8FLE|1|L1Human nuclear pre-60S ribosomal subunit (State L2)ELECTRON MICROSCOPY2.483526
1508FLD|1|L3+ 8FLD|1|L1Human nuclear pre-60S ribosomal subunit (State L1)ELECTRON MICROSCOPY2.583526
1518FL6|1|L3+ 8FL6|1|L1Human nuclear pre-60S ribosomal subunit (State J1)ELECTRON MICROSCOPY2.623559
1528FL7|1|L3+ 8FL7|1|L1Human nuclear pre-60S ribosomal subunit (State J2)ELECTRON MICROSCOPY2.553563
1538FLB|1|L3+ 8FLB|1|L1Human nuclear pre-60S ribosomal subunit (State K2)ELECTRON MICROSCOPY2.553574
1548FLA|1|L3+ 8FLA|1|L1Human nuclear pre-60S ribosomal subunit (State K1)ELECTRON MICROSCOPY2.633574
1558FLC|1|L3+ 8FLC|1|L1Human nuclear pre-60S ribosomal subunit (State K3)ELECTRON MICROSCOPY2.763527
1568FL9|1|L3+ 8FL9|1|L1Human nuclear pre-60S ribosomal subunit (State J3)ELECTRON MICROSCOPY2.753515
1578INE|1|2+ 8INE|1|8human nuclear pre-60S ribosomal particle - State G'ELECTRON MICROSCOPY3.23692
1588INF|1|2+ 8INF|1|8human nuclear pre-60S ribosomal particle - State F'ELECTRON MICROSCOPY33808
1598IDY|1|2+ 8IDY|1|8human nuclear pre-60S ribosomal particle - State FELECTRON MICROSCOPY33797
1608IDT|1|2+ 8IDT|1|8human nuclear pre-60S ribosomal particle - State GELECTRON MICROSCOPY2.83680
1616LSS|1|2+ 6LSS|1|8Cryo-EM structure of a pre-60S ribosomal subunit - state preAELECTRON MICROSCOPY3.233630
1626LU8|1|2+ 6LU8|1|8Cryo-EM structure of a human pre-60S ribosomal subunit - state AELECTRON MICROSCOPY3.133633
1638IE3|1|2+ 8IE3|1|8human nuclear pre-60S ribosomal particle - State EELECTRON MICROSCOPY3.33675
1648IPD|1|2+ 8IPD|1|8human nuclear pre-60S ribosomal particle - State CELECTRON MICROSCOPY3.23641
1658INK|1|2+ 8INK|1|8human nuclear pre-60S ribosomal particle - State DELECTRON MICROSCOPY3.23651
1668IPY|1|2+ 8IPY|1|8human nuclear pre-60S ribosomal particle - State D'ELECTRON MICROSCOPY3.23641
1678FL4|1|L3+ 8FL4|1|L1Human nuclear pre-60S ribosomal subunit (State I3)ELECTRON MICROSCOPY2.893640
1688FL3|1|L3+ 8FL3|1|L1Human nuclear pre-60S ribosomal subunit (State I2)ELECTRON MICROSCOPY2.533648
1698FL2|1|L3+ 8FL2|1|L1Human nuclear pre-60S ribosomal subunit (State I1)ELECTRON MICROSCOPY2.673649
1708FKZ|1|L3+ 8FKZ|1|L1Human nucleolar pre-60S ribosomal subunit (State G)ELECTRON MICROSCOPY3.042987
1718FL0|1|L3Human nucleolar pre-60S ribosomal subunit (State H)ELECTRON MICROSCOPY2.911558
1728IR3|1|2+ 8IR3|1|8human nuclear pre-60S ribosomal particle - State B'ELECTRON MICROSCOPY3.53696
1738IR1|1|2+ 8IR1|1|8human nuclear pre-60S ribosomal particle - State AELECTRON MICROSCOPY3.33524
1748RL2|1|L5+ 8RL2|1|L8Human pre-60S - State 5ELECTRON MICROSCOPY2.843538
1759QIW|1|L5+ 9QIW|1|L8Human pre-60S - State 3ELECTRON MICROSCOPY3.043293
1769GJ6|1|1Human 80S ribosome in complex with NatA in proximal and distal positionELECTRON MICROSCOPY3.91552
1779TV2|1|L5+ 9TV2|1|L880S ribosomes from primary B-cells infected with delta v-snoRNA1 EBVELECTRON MICROSCOPY2.13212
1789TT7|1|L5+ 9TT7|1|L880S ribosome of WT EBV infected human B-cellsELECTRON MICROSCOPY2.23211
1798FKR|1|L3+ 8FKR|1|L1Human nucleolar pre-60S ribosomal subunit (State B1)ELECTRON MICROSCOPY2.891921
1808FKP|1|L3+ 8FKP|1|L1Human nucleolar pre-60S ribosomal subunit (State A1)ELECTRON MICROSCOPY2.851659
1818FKQ|1|L3+ 8FKQ|1|L1Human nucleolar pre-60S ribosomal subunit (State A2)ELECTRON MICROSCOPY2.761715
1828FKS|1|L3+ 8FKS|1|L1Human nucleolar pre-60S ribosomal subunit (State B2)ELECTRON MICROSCOPY2.881976
1838FKW|1|L3+ 8FKW|1|L1Human nucleolar pre-60S ribosomal subunit (State D2)ELECTRON MICROSCOPY2.52429
1848FKU|1|L3+ 8FKU|1|L1Human nucleolar pre-60S ribosomal subunit (State C2)ELECTRON MICROSCOPY2.822337
1858FKX|1|L3+ 8FKX|1|L1Human nucleolar pre-60S ribosomal subunit (State E)ELECTRON MICROSCOPY2.592402
1868FKY|1|L3+ 8FKY|1|L1Human nucleolar pre-60S ribosomal subunit (State F)ELECTRON MICROSCOPY2.672740
1878FKV|1|L3+ 8FKV|1|L1Human nucleolar pre-60S ribosomal subunit (State D1)ELECTRON MICROSCOPY2.472365
1888FKT|1|L3+ 8FKT|1|L1Human nucleolar pre-60S ribosomal subunit (State C1)ELECTRON MICROSCOPY2.812277
1896SXO|1|L5Cryo-EM structure of the human Ebp1-ribosome complexELECTRON MICROSCOPY3.3268
1908ONY|1|5Human Methionine Aminopeptidase 2 at the 80S ribosomeELECTRON MICROSCOPY2.92156

Heat map of mutual geometric discrepancy, in Angstroms per nucleotide. The ordering in the heat map is the same as in the table. The colorbar ranges from 0 to the maximum observed discrepancy. Click above the diagonal to select a range of structures, below the diagonal to select two structures.


Coloring options:

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